"Nucleic Acids" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
High molecular weight polymers containing a mixture of purine and pyrimidine nucleotides chained together by ribose or deoxyribose linkages.
| Descriptor ID |
D009696
|
| MeSH Number(s) |
D13.444
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Nucleic Acids".
Below are MeSH descriptors whose meaning is more specific than "Nucleic Acids".
This graph shows the total number of publications written about "Nucleic Acids" by people in this website by year, and whether "Nucleic Acids" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 |
| 2001 | 0 | 1 | 1 |
| 2003 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2011 | 2 | 0 | 2 |
| 2013 | 1 | 1 | 2 |
| 2014 | 1 | 0 | 1 |
| 2015 | 1 | 2 | 3 |
| 2016 | 1 | 1 | 2 |
| 2017 | 0 | 1 | 1 |
| 2018 | 1 | 1 | 2 |
| 2019 | 8 | 1 | 9 |
| 2020 | 1 | 1 | 2 |
| 2022 | 4 | 0 | 4 |
| 2023 | 1 | 0 | 1 |
| 2024 | 7 | 1 | 8 |
| 2025 | 1 | 0 | 1 |
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Below are the most recent publications written about "Nucleic Acids" by people in Profiles.
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Hao K, Marshak-Rothstein A. Nucleic acid triggers of autoimmunity and autoinflammation. Curr Opin Immunol. 2025 Apr; 93:102535.
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Stillman JM, Kiniwa T, Schafer DP. Nucleic acid sensing in the central nervous system: Implications for neural circuit development, function, and degeneration. Immunol Rev. 2024 10; 327(1):71-82.
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Yamada K, Hariharan VN, Caiazzi J, Miller R, Ferguson CM, Sapp E, Fakih HH, Tang Q, Yamada N, Furgal RC, Paquette JD, Biscans A, Bramato BM, McHugh N, Summers A, Lochmann C, Godinho BMDC, Hildebrand S, Jackson SO, Echeverria D, Hassler MR, Alterman JF, DiFiglia M, Aronin N, Khvorova A. Enhancing siRNA efficacy in vivo with extended nucleic acid backbones. Nat Biotechnol. 2025 Jun; 43(6):904-913.
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Agrawal S. Considerations for Creating the Next Generation of RNA Therapeutics: Oligonucleotide Chemistry and Innate Immune Responses to Nucleic Acids. Nucleic Acid Ther. 2024 04; 34(2):37-51.
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Belgrad J, Fakih HH, Khvorova A. Nucleic Acid Therapeutics: Successes, Milestones, and Upcoming Innovation. Nucleic Acid Ther. 2024 04; 34(2):52-72.
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Belgrad J, Fakih HH, Johnson KC, Corey DR. Editorial: Nucleic Acids Research virtual issue dedicated to nucleic acid therapeutics, 2018-2023. Nucleic Acids Res. 2024 01 25; 52(2):511-512.
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Asohan J, Fakih HH, Das T, Sleiman HF. Control of the Assembly and Disassembly of Spherical Nucleic Acids Is Critical for Enhanced Gene Silencing. ACS Nano. 2024 02 06; 18(5):3996-4007.
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Roderick-Richardson JE, Lim SE, Suzuki S, Ahmad MH, Selway J, Suleiman R, Karna K, Lehman J, O'Donnell J, Castilla LH, Maelfait J, Rehwinkel J, Kelliher MA. ZBP1 activation triggers hematopoietic stem and progenitor cell death resulting in bone marrow failure in mice. Proc Natl Acad Sci U S A. 2024 Jan 23; 121(4):e2309628121.
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Sharma VK, Mangla P, Singh SK, Prasad AK. Triazole-linked Nucleic Acids: Synthesis, Therapeutics and Synthetic Biology Applications. Curr Org Synth. 2024; 21(4):436-455.
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Kaviani S, Fakih HH, Asohan J, Katolik A, Damha MJ, Sleiman HF. Sequence-Controlled Spherical Nucleic Acids: Gene Silencing, Encapsulation, and Cellular Uptake. Nucleic Acid Ther. 2023 08; 33(4):265-276.