Nucleic Acid Heteroduplexes
"Nucleic Acid Heteroduplexes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Double-stranded nucleic acid molecules (DNA-DNA or DNA-RNA) which contain regions of nucleotide mismatches (non-complementary). In vivo, these heteroduplexes can result from mutation or genetic recombination; in vitro, they are formed by nucleic acid hybridization. Electron microscopic analysis of the resulting heteroduplexes facilitates the mapping of regions of base sequence homology of nucleic acids.
| Descriptor ID |
D009692
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| MeSH Number(s) |
D13.444.500
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Nucleic Acid Heteroduplexes".
Below are MeSH descriptors whose meaning is more specific than "Nucleic Acid Heteroduplexes".
This graph shows the total number of publications written about "Nucleic Acid Heteroduplexes" by people in this website by year, and whether "Nucleic Acid Heteroduplexes" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1998 | 1 | 1 | 2 |
| 1999 | 0 | 1 | 1 |
| 2003 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Nucleic Acid Heteroduplexes" by people in Profiles.
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Li C, Zamore PD. Preparation of siRNA Duplexes. Cold Spring Harb Protoc. 2019 04 01; 2019(4).
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Samanta S, Martin CT. Insights into the mechanism of initial transcription in Escherichia coli RNA polymerase. J Biol Chem. 2013 Nov 01; 288(44):31993-2003.
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Liu X, Martin CT. Transcription elongation complex stability: the topological lock. J Biol Chem. 2009 Dec 25; 284(52):36262-36270.
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Liu X, Nakamura K, Wang Y, Zhang S, He J, Liu G, Dou S, Kubo A, Rusckowski M, Hnatowich D. Improved delivery in cell culture of radiolabeled antisense DNAs by duplex formation. Mol Imaging Biol. 2006 Sep-Oct; 8(5):278-83.
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Ping YH, Rana TM. Mechanism of site-specific psoralen photoadducts formation in triplex DNA directed by psoralen-conjugated oligonucleotides. Biochemistry. 2005 Feb 22; 44(7):2501-9.
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Cecchini S, Girouard S, Huels MA, Sanche L, Hunting DJ. Interstrand cross-links: a new type of gamma-ray damage in bromodeoxyuridine-substituted DNA. Biochemistry. 2005 Feb 15; 44(6):1932-40.
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Vernille JP, Kovell LC, Schneider JW. Peptide nucleic acid (PNA) amphiphiles: synthesis, self-assembly, and duplex stability. Bioconjug Chem. 2004 Nov-Dec; 15(6):1314-21.
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Jaskelioff M, Van Komen S, Krebs JE, Sung P, Peterson CL. Rad54p is a chromatin remodeling enzyme required for heteroduplex DNA joint formation with chromatin. J Biol Chem. 2003 Mar 14; 278(11):9212-8.
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Wu TH, Marinus MG. Deletion mutation analysis of the mutS gene in Escherichia coli. J Biol Chem. 1999 Feb 26; 274(9):5948-52.
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Cannon W, Gallegos MT, Casaz P, Buck M. Amino-terminal sequences of sigmaN (sigma54) inhibit RNA polymerase isomerization. Genes Dev. 1999 Feb 01; 13(3):357-70.