DNA

"DNA" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A deoxyribonucleotide polymer that is the primary genetic material of all cells. Eukaryotic and prokaryotic organisms normally contain DNA in a double-stranded state, yet several important biological processes transiently involve single-stranded regions. DNA, which consists of a polysugar-phosphate backbone possessing projections of purines (adenine and guanine) and pyrimidines (thymine and cytosine), forms a double helix that is held together by hydrogen bonds between these purines and pyrimidines (adenine to thymine and guanine to cytosine).

Descriptor ID	D004247
MeSH Number(s)	D13.444.308
Concept/Terms	DNA DNA Deoxyribonucleic Acid DNA, Double-Stranded DNA, Double-Stranded DNA, Double Stranded Double-Stranded DNA ds-DNA ds DNA

Below are MeSH descriptors whose meaning is more general than "DNA".

Chemicals and Drugs [D]
Nucleic Acids, Nucleotides, and Nucleosides [D13]
Nucleic Acids [D13.444]
DNA [D13.444.308]

Below are MeSH descriptors whose meaning is related to "DNA".

Below are MeSH descriptors whose meaning is more specific than "DNA".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "DNA" by people in this website by year, and whether "DNA" was a major or minor topic of these publications.

Bar chart showing 589 publications over 31 distinct years, with a maximum of 33 publications in 2012

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	3	13	16
1996	1	6	7
1997	3	4	7
1998	5	5	10
1999	6	3	9
2000	6	5	11
2001	6	11	17
2002	11	17	28
2003	11	14	25
2004	12	15	27
2005	11	15	26
2006	12	13	25
2007	7	12	19
2008	8	15	23
2009	10	13	23
2010	9	13	22
2011	8	11	19
2012	25	8	33
2013	16	13	29
2014	13	9	22
2015	12	8	20
2016	12	13	25
2017	11	5	16
2018	11	11	22
2019	12	5	17
2020	5	5	10
2021	4	10	14
2022	0	18	18
2023	4	24	28
2024	2	15	17
2025	4	0	4

Below are the most recent publications written about "DNA" by people in Profiles.

David SS, Pacheco BA, Kishimoto K, Vantine S, Hu K, Liu H, Davis DL, Tran H, Sallis BF, Ali L, Haynes CM, McCormick BA, Zhu LJ, Flavahan WA. Multidimensional third-generation sequencing of modified DNA bases allows interrogation of complex biological systems. Nat Commun. 2025 Jul 01; 16(1):5676.

View in: PubMed
Li J, Zhai R, Xiao H, Chen Y, Cheng W, Yang X, Wang K, Yang Y, Huang J. Ultrahigh-Capacity Vertical Encoded Micro-Spherical Nucleic Acids for Multiplexed Detection. Anal Chem. 2025 Jul 15; 97(27):14792-14799.

View in: PubMed
Oikemus S, Hu K, Shin M, Idrizi F, Goodman-Khan A, Kolb A, Ghanta KS, Lee J, Wagh A, Wolfe SA, Zhu LJ, Watts JK, Lawson ND. Identifying optimal conditions for precise knock-in of exogenous DNA into the zebrafish genome. Development. 2025 Jun 15; 152(12).

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Mishra N, Mohs M, Wittmann N, Gross S, Thompson PR, Bossaller L. PLC and PAD2 Regulate Extracellular Calcium-Triggered Release of Macrophage Extracellular DNA Traps. Eur J Immunol. 2025 Apr; 55(4):e202350942.

View in: PubMed
Seddon JM, De D, Grunenkovaite L, Ferrara D. Clinical and Imaging Characteristics of PRPH2 Retinopathies in a Longitudinal Cohort and Diagnostic Implications. Invest Ophthalmol Vis Sci. 2024 Dec 02; 65(14):31.

View in: PubMed
Greiner-Tollersrud OK, Krausz M, Boehler V, Polyzou A, Seidl M, Spahiu A, Abdullah Z, Andryka-Cegielski K, Dominick FI, Huebscher K, Goschin A, Smulski CR, Trompouki E, Link R, Ebersbach H, Srinivas H, Marchant M, Sogkas G, Staab D, V?gb? C, Guerini D, Baasch S, Latz E, Hartmann G, Henneke P, Geiger R, Peng XP, Grimbacher B, Bartok E, Alseth I, Warncke M, Proietti M. ADA2 is a lysosomal deoxyadenosine deaminase acting on DNA involved in regulating TLR9-mediated immune sensing of DNA. Cell Rep. 2024 11 26; 43(11):114899.

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Dong M, Fitzgerald KA. DNA-sensing pathways in health, autoinflammatory and autoimmune diseases. Nat Immunol. 2024 Nov; 25(11):2001-2014.

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MalagodaPathiranage K, Banerjee R, Martin CT. A new approach to RNA synthesis: immobilization of stably and functionally co-tethered promoter DNA and T7 RNA polymerase. Nucleic Acids Res. 2024 Sep 23; 52(17):10607-10618.

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Bonnell VA, Zhang Y, Brown AS, Horton J, Josling GA, Chiu TP, Rohs R, Mahony S, Gord?n R, Llin?s M. DNA sequence and chromatin differentiate sequence-specific transcription factor binding in the human malaria parasite Plasmodium falciparum. Nucleic Acids Res. 2024 Sep 23; 52(17):10161-10179.

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Conte M, Abraham A, Esposito A, Yang L, Gibcus JH, Parsi KM, Vercellone F, Fontana A, Di Pierno F, Dekker J, Nicodemi M. Polymer Physics Models Reveal Structural Folding Features of Single-Molecule Gene Chromatin Conformations. Int J Mol Sci. 2024 Sep 23; 25(18).

View in: PubMed

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