An autophagy related protein which functions as a core subunit of PHOSPHATIDYLINOSITOL 3-KINASE MULTIPROTEIN COMPLEXES. It mediates the formation of phosphatidylinositol 3-phosphate and functions in AUTOPHAGY, where it is required for maturation of the AUTOPHAGOSOME. It also functions in ENDOCYTOSIS and CYTOKINESIS as part of a separate complex. Beclin-1 associates with INTRACELLULAR MEMBRANES and interacts with the PROTO-ONCOGENE PROTEINS C-BCL-2 and BCL-X PROTEIN.

Descriptor ID	D000071186
MeSH Number(s)	D12.644.360.075.335 D12.776.094.500 D12.776.476.075.335
Concept/Terms	Beclin-1 Beclin-1 Beclin 1 Beclin-1 Protein Beclin 1 Protein GT197 Protein ATG-6 Protein ATG 6 Protein Coiled-coil Myosin-like Bcl2-interacting Protein Coiled coil Myosin like Bcl2 interacting Protein Beclin1 ATG6 Protein

Below are MeSH descriptors whose meaning is more general than "Beclin-1".

Below are MeSH descriptors whose meaning is related to "Beclin-1".

Below are MeSH descriptors whose meaning is more specific than "Beclin-1".