Autophagy-Related Protein 7
"Autophagy-Related Protein 7" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An autophagy related protein that is similar to UBIQUITIN-ACTIVATING ENZYME E1. It functions in CYTOPLASM to VACUOLE transport (Cvt) and AUTOPHAGY by activating ATG12 PROTEIN for its conjugation with ATG5 PROTEIN, as well as the conjugation of ATG8 FAMILY PROTEINS with phosphatidylethanolamine for ATG8 association to Cvt vesicles and AUTOPHAGOSOME membranes. It is also required for the nitrogen starvation response in yeast, MITOPHAGY; and autophagic cell death induced by CASPASE 8 inhibition.
Descriptor ID |
D000071193
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MeSH Number(s) |
D12.776.094.399
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Concept/Terms |
Autophagy-Related Protein 7- Autophagy-Related Protein 7
- Autophagy Related Protein 7
- ATG7 Protein
- Ubiquitin-Activating Enzyme E1-like Protein
- Ubiquitin Activating Enzyme E1 like Protein
- Ubiquitin-Like Modifier-Activating Enzyme ATG7
- Ubiquitin Like Modifier Activating Enzyme ATG7
- ATG12-Activating Enzyme E1 ATG7
- ATG12 Activating Enzyme E1 ATG7
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Below are MeSH descriptors whose meaning is more general than "Autophagy-Related Protein 7".
Below are MeSH descriptors whose meaning is more specific than "Autophagy-Related Protein 7".
This graph shows the total number of publications written about "Autophagy-Related Protein 7" by people in this website by year, and whether "Autophagy-Related Protein 7" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2004 | 0 | 1 | 1 |
2011 | 0 | 1 | 1 |
2013 | 0 | 1 | 1 |
2016 | 1 | 0 | 1 |
2020 | 0 | 1 | 1 |
2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Autophagy-Related Protein 7" by people in Profiles.
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Mittal E, Prasad GVRK, Upadhyay S, Sadadiwala J, Olive AJ, Yang G, Sassetti CM, Philips JA. Mycobacterium tuberculosis virulence lipid PDIM inhibits autophagy in mice. Nat Microbiol. 2024 Nov; 9(11):2970-2984.
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Ligon C, Seong E, Schroeder EJ, DeKorver NW, Yuan L, Chaudoin TR, Cai Y, Buch S, Bonasera SJ, Arikkath J. d-Catenin engages the autophagy pathway to sculpt the developing dendritic arbor. J Biol Chem. 2020 08 07; 295(32):10988-11001.
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Park SM, Ou J, Chamberlain L, Simone TM, Yang H, Virbasius CM, Ali AM, Zhu LJ, Mukherjee S, Raza A, Green MR. U2AF35(S34F) Promotes Transformation by Directing Aberrant ATG7 Pre-mRNA 3' End Formation. Mol Cell. 2016 05 19; 62(4):479-90.
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Chang TK, Shravage BV, Hayes SD, Powers CM, Simin RT, Wade Harper J, Baehrecke EH. Uba1 functions in Atg7- and Atg3-independent autophagy. Nat Cell Biol. 2013 Sep; 15(9):1067-78.
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Florey O, Kim SE, Sandoval CP, Haynes CM, Overholtzer M. Autophagy machinery mediates macroendocytic processing and entotic cell death by targeting single membranes. Nat Cell Biol. 2011 Oct 16; 13(11):1335-43.
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Yu L, Lenardo MJ, Baehrecke EH. Autophagy and caspases: a new cell death program. Cell Cycle. 2004 Sep; 3(9):1124-6.