beta Catenin

"beta Catenin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A multi-functional catenin that participates in CELL ADHESION and nuclear signaling. Beta catenin binds CADHERINS and helps link their cytoplasmic tails to the ACTIN in the CYTOSKELETON via ALPHA CATENIN. It also serves as a transcriptional co-activator and downstream component of WNT PROTEIN-mediated SIGNAL TRANSDUCTION PATHWAYS.

Descriptor ID	D051176
MeSH Number(s)	D12.776.091.249 D12.776.220.145.500 D12.776.930.130
Concept/Terms	beta Catenin beta Catenin Catenin, beta beta-Catenin

Below are MeSH descriptors whose meaning is more general than "beta Catenin".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Armadillo Domain Proteins [D12.776.091]
beta Catenin [D12.776.091.249]
Cytoskeletal Proteins [D12.776.220]
Catenins [D12.776.220.145]
beta Catenin [D12.776.220.145.500]
Transcription Factors [D12.776.930]
beta Catenin [D12.776.930.130]

Below are MeSH descriptors whose meaning is related to "beta Catenin".

Below are MeSH descriptors whose meaning is more specific than "beta Catenin".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "beta Catenin" by people in this website by year, and whether "beta Catenin" was a major or minor topic of these publications.

Bar chart showing 62 publications over 25 distinct years, with a maximum of 7 publications in 2013

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1997	0	1	1
1999	0	3	3
2000	0	1	1
2002	0	1	1
2003	0	1	1
2004	0	2	2
2005	0	1	1
2006	2	2	4
2007	3	0	3
2008	2	2	4
2009	0	1	1
2010	0	1	1
2011	1	1	2
2012	2	0	2
2013	5	2	7
2014	0	2	2
2015	1	1	2
2016	3	3	6
2017	0	4	4
2018	1	3	4
2019	2	0	2
2020	0	1	1
2021	1	2	3
2022	1	0	1
2023	0	3	3

Below are the most recent publications written about "beta Catenin" by people in Profiles.

Chaudagar K, Hieromnimon HM, Kelley A, Labadie B, Shafran J, Rameshbabu S, Drovetsky C, Bynoe K, Solanki A, Markiewicz E, Fan X, Loda M, Patnaik A. Suppression of Tumor Cell Lactate-generating Signaling Pathways Eradicates Murine PTEN/p53-deficient Aggressive-variant Prostate Cancer via Macrophage Phagocytosis. Clin Cancer Res. 2023 12 01; 29(23):4930-4940.

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Stavre Z, Kim JM, Yang YS, N?ndel K, Chaugule S, Sato T, Park KH, Gao G, Gravallese EM, Shim JH. Schnurri-3 inhibition suppresses bone and joint damage in models of rheumatoid arthritis. Proc Natl Acad Sci U S A. 2023 05 09; 120(19):e2218019120.

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Mou H, Eskiocak O, ?zler KA, Gorman M, Yue J, Jin Y, Wang Z, Gao Y, Janowitz T, Meyer HV, Yu T, Wilkinson JE, Kucukural A, Ozata DM, Beyaz S. CRISPR-induced exon skipping of ?-catenin reveals tumorigenic mutants driving distinct subtypes of liver cancer. J Pathol. 2023 04; 259(4):415-427.

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Garcia E, Ladak Z, Landry T, Wollin M, Persad ARL, Sergi CM, Huynh HQ, Persad R, Persad S. Epithelial-mesenchymal transition, regulated by ?-catenin and Twist, leads to esophageal wall remodeling in pediatric eosinophilic esophagitis. PLoS One. 2022; 17(3):e0264622.

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Chaugule S, Kim JM, Yang YS, Knobeloch KP, He X, Shim JH. Deubiquitinating Enzyme USP8 Is Essential for Skeletogenesis by Regulating Wnt Signaling. Int J Mol Sci. 2021 Sep 24; 22(19).

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Madahian S, Judelson R, Zhu X, Meng X, Dresser K, Hutchinson L, Bledsoe JR. CD56 expression in basaloid anal squamous cell carcinoma - A potential diagnostic pitfall. Ann Diagn Pathol. 2021 Aug; 53:151758.

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Zhang CH, Liu H, Zhao WL, Zhao WX, Zhou HM, Shao RG. G3BP1 promotes human breast cancer cell proliferation through coordinating with GSK-3? and stabilizing ?-catenin. Acta Pharmacol Sin. 2021 11; 42(11):1900-1912.

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Pandey A, Stawiski EW, Durinck S, Gowda H, Goldstein LD, Barbhuiya MA, Schr?der MS, Sreenivasamurthy SK, Kim SW, Phalke S, Suryamohan K, Lee K, Chakraborty P, Kode V, Shi X, Chatterjee A, Datta K, Khan AA, Subbannayya T, Wang J, Chaudhuri S, Gupta S, Shrivastav BR, Jaiswal BS, Poojary SS, Bhunia S, Garcia P, Bizama C, Rosa L, Kwon W, Kim H, Han Y, Yadav TD, Ramprasad VL, Chaudhuri A, Modrusan Z, Roa JC, Tiwari PK, Jang JY, Seshagiri S. Integrated genomic analysis reveals mutated ELF3 as a potential gallbladder cancer vaccine candidate. Nat Commun. 2020 08 24; 11(1):4225.

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Saenz DT, Fiskus W, Mill CP, Perera D, Manshouri T, Lara BH, Karkhanis V, Sharma S, Horrigan SK, Bose P, Kadia TM, Masarova L, DiNardo CD, Borthakur G, Khoury JD, Takahashi K, Bhaskara S, Lin CY, Green MR, Coarfa C, Crews CM, Verstovsek S, Bhalla KN. Mechanistic basis and efficacy of targeting the ?-catenin-TCF7L2-JMJD6-c-Myc axis to overcome resistance to BET inhibitors. Blood. 2020 04 09; 135(15):1255-1269.

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Olea-Flores M, Zu?iga-Eulogio M, Tacuba-Saavedra A, Bueno-Salgado M, S?nchez-Carvajal A, Vargas-Santiago Y, Mendoza-Catal?n MA, P?rez Salazar E, Garc?a-Hern?ndez A, Padilla-Benavides T, Navarro-Tito N. Leptin Promotes Expression of EMT-Related Transcription Factors and Invasion in a Src and FAK-Dependent Pathway in MCF10A Mammary Epithelial Cells. Cells. 2019 09 24; 8(10).

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