Below are the most recent publications written about "Cell Differentiation" by people in Profiles.
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Deehan M, Sapp E, Iwanowicz A, Kothuis J, Weisman E, Liu S, Jones E, Iuliano M, Robertson R, Seeley C, Li Z, Noori A, Li X, Das S, Brodsky M, Aronin N, DiFiglia M, Kegel-Gleason KB. ESC derived human cortical neurons harboring the NACC1 c.892C?>?T p.R298W missense mutation exhibit molecular differences from controls that influence neuronal maturation. Hum Mol Genet. 2025 Oct 14; 34(21):1796-1807.
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Lynch AC, Hioki KA, Liang X, Thesmar I, Cernjul J, He XD, Mager J, Cui W, Alfandari D, Pobezinskaya EL, Pobezinsky LA. A Dapl1+ subpopulation of na?ve CD8 T cells is enriched for memory-lineage precursors. Sci Adv. 2025 Aug 22; 11(34):eadx5687.
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Hansen BC, Arian CM, Zeng Y, Takezawa MG, Theberge AB, Faustman EM, Thummel KE, Kelly EJ. Leveraging RNA-seq deconvolution to improve complex in vitro model characterization. J Biol Chem. 2025 Sep; 301(9):110510.
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Liu S, Li L, Zhang F, Garcia-Corral M, Meyer K, Fortuna PRJ, van Sambeek B, Appleton E, Ng AHM, Khoshakhlagh P, Lu YR, Cameron J, Ramirez RN, Chen Y, Wu CT, Huang JY, Tan Y, Chao G, Aach J, Lim ET, Tam JM, Raychaudhuri S, Church GM. Iterative transcription factor screening enables rapid generation of microglia-like cells from human iPSC. Nat Commun. 2025 Jun 10; 16(1):5136.
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Fike AJ, Bricker KN, Gonzalez MV, Maharjan A, Bui T, Nuon K, Emrich SM, Weber JL, Luckenbill SA, Choi NM, Sauteraud R, Liu DJ, Olsen NJ, Caricchio R, Trebak M, Chodisetti SB, Rahman ZSM. IRF7 controls spontaneous autoimmune germinal center and plasma cell checkpoints. J Exp Med. 2025 Jul 07; 222(7).
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Abou Nader N, Jakuc N, Meinsohn MC, Charrier L, Banville L, Brind'Amour J, Paquet M, St-Jean G, Boerboom D, Mao J, P?pin D, Breault DT, Zamberlam G, Boyer A. Hippo Signaling Is Essential for the Maintenance of Zona Glomerulosa Cell Fate in the Murine Adrenal Cortex. Endocrinology. 2025 Apr 22; 166(6).
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Liu Z, Tan Y, Flynn WF, Sun L, Pratumkaew P, Alcoforado Diniz J, Oliveira NAJ, McDonough JA, Skarnes WC, Robson P. HAND1, partially mediated through ape-specific LTR binding, is essential for human extra-embryonic mesenchyme derivation from iPSCs. Cell Rep. 2025 Apr 22; 44(4):115568.
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Cheng YF, Kempfle JS, Chiang H, Tani K, Wang Q, Chen SH, Lenz D, Chen WY, Wu W, Petrillo M, Edge ASB. Sox2 interacts with Atoh1 and Huwe1 loci to regulate Atoh1 transcription and stability during hair cell differentiation. PLoS Genet. 2025 Jan; 21(1):e1011573.
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Pierson Smela M, Kramme CC, Fortuna PRJ, Wolf B, Goel S, Adams J, Ma C, Velychko S, Widocki U, Srikar Kavirayuni V, Chen T, Vincoff S, Dong E, Kohman RE, Kobayashi M, Shioda T, Church GM, Chatterjee P. Rapid human oogonia-like cell specification via transcription factor-directed differentiation. EMBO Rep. 2025 Feb; 26(4):1114-1143.
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Mohammadhosseini M, Enright T, Duvall A, Chitsazan A, Lin HY, Ors A, Davis BA, Nikolova O, Bresciani E, Diemer J, Craft K, Menezes AC, Merguerian M, Chong S, Calvo KR, Deuitch NT, Glushakow-Smith S, Gritsman K, Godley LA, Horwitz MS, Keel S, Castilla LH, Demir E, Mohammed H, Liu P, Agarwal A. Targeting the CD74 signaling axis suppresses inflammation and rescues defective hematopoiesis in RUNX1-familial platelet disorder. Sci Transl Med. 2025 Jan 08; 17(780):eadn9832.