"Leukocyte Rolling" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Movement of tethered, spherical LEUKOCYTES along the endothelial surface of the microvasculature. The tethering and rolling involves interaction with SELECTINS and other adhesion molecules in both the ENDOTHELIUM and leukocyte. The rolling leukocyte then becomes activated by CHEMOKINES, flattens out, and firmly adheres to the endothelial surface in preparation for transmigration through the interendothelial cell junction. (From Abbas, Cellular and Molecular Immunology, 3rd ed)
Descriptor ID |
D036904
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MeSH Number(s) |
G04.198.424.233.500
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Concept/Terms |
Leukocyte Rolling- Leukocyte Rolling
- Rolling, Leukocyte
- Leucocyte Rolling
- Rolling, Leucocyte
|
Below are MeSH descriptors whose meaning is more general than "Leukocyte Rolling".
Below are MeSH descriptors whose meaning is more specific than "Leukocyte Rolling".
This graph shows the total number of publications written about "Leukocyte Rolling" by people in this website by year, and whether "Leukocyte Rolling" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2005 | 1 | 0 | 1 |
2006 | 0 | 1 | 1 |
2009 | 0 | 1 | 1 |
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Below are the most recent publications written about "Leukocyte Rolling" by people in Profiles.
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Kampfrath T, Deiuliis JA, Moffatt-Bruce SD, Anderson J, Sun Q, Wood K, Ostrowski MC, Rajagopalan S. A mouse model of yellow fluorescent protein (YFP) expression in hematopoietic cells to assess leukocyte-endothelial interactions in the microcirculation. Microvasc Res. 2009 Dec; 78(3):294-300.
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Yang D, Zhang Y, Nguyen HG, Koupenova M, Chauhan AK, Makitalo M, Jones MR, St Hilaire C, Seldin DC, Toselli P, Lamperti E, Schreiber BM, Gavras H, Wagner DD, Ravid K. The A2B adenosine receptor protects against inflammation and excessive vascular adhesion. J Clin Invest. 2006 Jul; 116(7):1913-23.
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Uchimura K, Gauguet JM, Singer MS, Tsay D, Kannagi R, Muramatsu T, von Andrian UH, Rosen SD. A major class of L-selectin ligands is eliminated in mice deficient in two sulfotransferases expressed in high endothelial venules. Nat Immunol. 2005 Nov; 6(11):1105-13.