"Plasminogen" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Precursor of plasmin (FIBRINOLYSIN). It is a single-chain beta-globulin of molecular weight 80-90,000 found mostly in association with fibrinogen in plasma; plasminogen activators change it to fibrinolysin. It is used in wound debriding and has been investigated as a thrombolytic agent.
Descriptor ID |
D010958
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MeSH Number(s) |
D08.622.610 D12.776.124.790.223.580 D12.776.377.715.182.580
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Concept/Terms |
Glu-Plasminogen- Glu-Plasminogen
- Glu Plasminogen
- Glutamyl Plasminogen
- Plasminogen, Glutamyl
- Glutamic Acid 1-Plasminogen
- 1-Plasminogen, Glutamic Acid
- Glutamic Acid 1 Plasminogen
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Below are MeSH descriptors whose meaning is more general than "Plasminogen".
Below are MeSH descriptors whose meaning is more specific than "Plasminogen".
This graph shows the total number of publications written about "Plasminogen" by people in this website by year, and whether "Plasminogen" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1995 | 2 | 0 | 2 |
1996 | 2 | 0 | 2 |
1997 | 1 | 0 | 1 |
2005 | 1 | 0 | 1 |
2008 | 1 | 0 | 1 |
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Below are the most recent publications written about "Plasminogen" by people in Profiles.
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Eren E, Murphy M, Goguen J, van den Berg B. An active site water network in the plasminogen activator pla from Yersinia pestis. Structure. 2010 Jul 14; 18(7):809-18.
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Gramling MW, Beaulieu LM, Church FC. Activated protein C enhances cell motility of endothelial cells and MDA-MB-231 breast cancer cells by intracellular signal transduction. Exp Cell Res. 2010 Feb 01; 316(3):314-28.
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Bautz DJ, Preston GA, Lionaki S, Hewins P, Wolberg AS, Yang JJ, Hogan SL, Chin H, Moll S, Jennette JC, Falk RJ. Antibodies with dual reactivity to plasminogen and complementary PR3 in PR3-ANCA vasculitis. J Am Soc Nephrol. 2008 Dec; 19(12):2421-9.
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Cheng Q, Zhao Y, Lawson WE, Polosukhin VV, Johnson JE, Blackwell TS, Gailani D. The effects of intrinsic pathway protease deficiencies on plasminogen-deficient mice. Blood. 2005 Nov 01; 106(9):3055-7.
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Goguen JD, Bugge T, Degen JL. Role of the pleiotropic effects of plasminogen deficiency in infection experiments with plasminogen-deficient mice. Methods. 2000 Jun; 21(2):179-83.
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Hu LT, Pratt SD, Perides G, Katz L, Rogers RA, Klempner MS. Isolation, cloning, and expression of a 70-kilodalton plasminogen binding protein of Borrelia burgdorferi. Infect Immun. 1997 Dec; 65(12):4989-95.
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Klempner MS, Noring R, Epstein MP, McCloud B, Rogers RA. Binding of human urokinase type plasminogen activator and plasminogen to Borrelia species. J Infect Dis. 1996 Jul; 174(1):97-104.
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Perides G, Noring R, Klempner MS. Inhibition of Borrelia burgdorferi-bound fibrinolytic enzymes by alpha2-antiplasmin, PAI-1 and PAI-2. Biochem Biophys Res Commun. 1996 Feb 27; 219(3):690-5.
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Hu LT, Perides G, Noring R, Klempner MS. Binding of human plasminogen to Borrelia burgdorferi. Infect Immun. 1995 Sep; 63(9):3491-6.
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Loscalzo J, Pasche B, Ouimet H, Freedman JE. Platelets and plasminogen activation. Thromb Haemost. 1995 Jul; 74(1):291-3.