Mycobacterium tuberculosis

"Mycobacterium tuberculosis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A species of gram-positive, aerobic bacteria that produces TUBERCULOSIS in humans, other primates, CATTLE; DOGS; and some other animals which have contact with humans. Growth tends to be in serpentine, cordlike masses in which the bacilli show a parallel orientation.

Descriptor ID	D009169
MeSH Number(s)	B03.510.024.049.525.500.702 B03.510.460.400.410.552.552.702
Concept/Terms	Mycobacterium tuberculosis Mycobacterium tuberculosis Mycobacterium tuberculosis H37Rv Mycobacterium tuberculosis H37Rv

Below are MeSH descriptors whose meaning is more general than "Mycobacterium tuberculosis".

Organisms [B]
Bacteria [B03]
Gram-Positive Bacteria [B03.510]
Actinobacteria [B03.510.024]
Actinomycetales [B03.510.024.049]
Mycobacteriaceae [B03.510.024.049.525]
Mycobacterium [B03.510.024.049.525.500]
Mycobacterium tuberculosis [B03.510.024.049.525.500.702]
Gram-Positive Rods [B03.510.460]
Gram-Positive Asporogenous Rods [B03.510.460.400]
Gram-Positive Asporogenous Rods, Regular [B03.510.460.400.410]
Mycobacteriaceae [B03.510.460.400.410.552]
Mycobacterium [B03.510.460.400.410.552.552]
Mycobacterium tuberculosis [B03.510.460.400.410.552.552.702]

Below are MeSH descriptors whose meaning is related to "Mycobacterium tuberculosis".

Below are MeSH descriptors whose meaning is more specific than "Mycobacterium tuberculosis".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Mycobacterium tuberculosis" by people in this website by year, and whether "Mycobacterium tuberculosis" was a major or minor topic of these publications.

Bar chart showing 304 publications over 31 distinct years, with a maximum of 18 publications in 2025

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	2	0	2
1997	2	0	2
1998	2	0	2
1999	2	1	3
2000	1	1	2
2001	4	0	4
2002	3	3	6
2003	7	0	7
2004	4	0	4
2005	7	2	9
2006	7	0	7
2007	9	2	11
2008	15	1	16
2009	8	1	9
2010	9	2	11
2011	9	5	14
2012	13	3	16
2013	10	6	16
2014	10	1	11
2015	14	3	17
2016	10	4	14
2017	7	7	14
2018	13	3	16
2019	9	6	15
2020	9	3	12
2021	8	2	10
2022	13	0	13
2023	12	0	12
2024	9	1	10
2025	15	3	18
2026	1	0	1

Below are the most recent publications written about "Mycobacterium tuberculosis" by people in Profiles.

Sharma P, Sharma RD, Sarkar B, Panwar V, Das M, Singh LV, Jain N, Chaturvedi S, Mehra L, Rathee A, Sharma S, Foo S, Lee A, N PK, Das P, Viswanathan V, Kornfeld H, Howland SW, Babu S, Nandicoori VK, Singhal A, Kumar D. Ly6G+ granulocytes-derived IL-17 limits protective host responses and promotes tuberculosis pathogenesis. Elife. 2026 Feb 05; 13.

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Puffal J, Sparks IL, Brenner JR, Li X, Leszyk JD, Hayashi JM, Shaffer SA, Morita YS. Compartmentalized cell envelope biosynthesis in Mycobacterium tuberculosis. mBio. 2026 Jan 14; 17(1):e0268025.

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Mortensen R, Arlehamn CSL, Coler RN, Gerner MY, Goletti D, Lewinsohn DA, Modlin RL, Musvosvi M, Rengarajan J, Urdahl KB, Walzl G, Behar SM, Barber DL. T cell-macrophage interactions in tuberculosis: What we've got here is failure to communicate. J Intern Med. 2026 Jan; 299(1):44-65.

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Bridges K, Awany D, Gela A, Mwambene TD, Kurtz SL, Baker RE, Elkins KL, Sassetti CM, Scriba TJ, Lauffenburger DA. Cross-species blood transcriptional correlates of BCG-mediated protection against tuberculosis include innate and adaptive immune processes. JCI Insight. 2025 Dec 22; 10(24).

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Bond AN, Orzechowski M, Zhang S, Ben-Zion I, Lemmer A, Garry N, Lee K, Chen M, Delano K, Gath E, Golas AL, Nietupski R, Fitzgerald M, Ehrt S, Rubin EJ, Sassetti CM, Schnappinger D, Shoresh N, Hunt DK, Gomez JE, Hung DT. Reference-based chemical-genetic interaction profiling to elucidate small molecule mechanism of action in Mycobacterium tuberculosis. Nat Commun. 2025 Nov 03; 16(1):9673.

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Dasan B, Munisankar S, Kumar NP, Moideen K, Pandiarajan AN, Nott S, Viswanathan V, Shanmugam S, Hissar S, Thiruvengadam K, Kornfeld H, Babu S. Impact of cytomegalovirus exposure on disease severity, bacterial burden, immune responses and treatment outcomes in tuberculosis. Front Immunol. 2025; 16:1612709.

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Shinkawa T, Chang E, Rakib T, Cavallo K, Lai R, Behar SM. CD226 identifies effector CD8+ T cells during tuberculosis and costimulates recognition of Mycobacterium tuberculosis-infected macrophages. Cell Rep. 2025 Sep 23; 44(9):116184.

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Jinich A, Zaveri A, DeJesus MA, Spencer A, Almada-Monter R, Flores-Bautista E, Smith CM, Sassetti CM, Rock JM, Ehrt S, Schnappinger D, Ioerger TR, Rhee KY. The Mycobacterium tuberculosis Transposon Sequencing Database (MtbTnDB): A Large-Scale Guide to Genetic Conditional Essentiality. Mol Microbiol. 2025 Jul; 124(1):91-101.

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Lefran?ais E, Hudrisier D, Neyrolles O, Behar SM, Ernst JD. Finding and filling the knowledge gaps in mechanisms of T cell-mediated TB immunity to inform vaccine design. Nat Rev Immunol. 2025 Nov; 25(11):798-815.

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Grace PS, Peters JM, Sixsmith J, Lu R, Irvine EB, Luedeman C, Fenderson BA, Vickers A, Slein MD, McKitrick T, Wei MH, Cummings RD, Wallace A, Cavacini LA, Choudhary A, Proulx MK, Sundling C, K?llenius G, Reljic R, Ernst JD, Casadevall A, Locht C, Pinter A, Sassetti CM, Bryson BD, Fortune SM, Alter G. Antibody-Fab and -Fc features promote Mycobacterium tuberculosis restriction. Immunity. 2025 Jun 10; 58(6):1586-1597.e5.

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