Mycobacterium tuberculosis

"Mycobacterium tuberculosis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A species of gram-positive, aerobic bacteria that produces TUBERCULOSIS in humans, other primates, CATTLE; DOGS; and some other animals which have contact with humans. Growth tends to be in serpentine, cordlike masses in which the bacilli show a parallel orientation.

Descriptor ID	D009169
MeSH Number(s)	B03.510.024.049.525.500.702 B03.510.460.400.410.552.552.702
Concept/Terms	Mycobacterium tuberculosis Mycobacterium tuberculosis Mycobacterium tuberculosis H37Rv Mycobacterium tuberculosis H37Rv

Below are MeSH descriptors whose meaning is more general than "Mycobacterium tuberculosis".

Organisms [B]
Bacteria [B03]
Gram-Positive Bacteria [B03.510]
Actinobacteria [B03.510.024]
Actinomycetales [B03.510.024.049]
Mycobacteriaceae [B03.510.024.049.525]
Mycobacterium [B03.510.024.049.525.500]
Mycobacterium tuberculosis [B03.510.024.049.525.500.702]
Gram-Positive Rods [B03.510.460]
Gram-Positive Asporogenous Rods [B03.510.460.400]
Gram-Positive Asporogenous Rods, Regular [B03.510.460.400.410]
Mycobacteriaceae [B03.510.460.400.410.552]
Mycobacterium [B03.510.460.400.410.552.552]
Mycobacterium tuberculosis [B03.510.460.400.410.552.552.702]

Below are MeSH descriptors whose meaning is related to "Mycobacterium tuberculosis".

Below are MeSH descriptors whose meaning is more specific than "Mycobacterium tuberculosis".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Mycobacterium tuberculosis" by people in this website by year, and whether "Mycobacterium tuberculosis" was a major or minor topic of these publications.

Bar chart showing 284 publications over 31 distinct years, with a maximum of 16 publications in 2008 and 2012 and 2015 and 2018

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	0	1	1
1996	2	0	2
1997	2	0	2
1998	2	0	2
1999	2	1	3
2000	0	1	1
2001	4	0	4
2002	3	3	6
2003	7	0	7
2004	4	0	4
2005	7	2	9
2006	7	0	7
2007	9	2	11
2008	15	1	16
2009	8	1	9
2010	9	2	11
2011	9	4	13
2012	13	3	16
2013	10	5	15
2014	10	1	11
2015	13	3	16
2016	10	4	14
2017	7	5	12
2018	12	4	16
2019	8	6	14
2020	9	3	12
2021	7	2	9
2022	11	0	11
2023	12	0	12
2024	9	1	10
2025	7	1	8

Below are the most recent publications written about "Mycobacterium tuberculosis" by people in Profiles.

Liu Y, Brown CM, Borges N, Nobre RN, Erramilli S, Belcher Dufrisne M, Kloss B, Giacometti S, Esteves AM, Tim?teo CG, Tokarz P, Cater RJ, Lowary TL, Morita YS, Kossiakoff AA, Santos H, Stansfeld PJ, Nygaard R, Mancia F. Mechanistic studies of mycobacterial glycolipid biosynthesis by the mannosyltransferase PimE. Nat Commun. 2025 Apr 29; 16(1):3974.

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Proulx MK, Wiggins CD, Reames CJ, Wu C, Kiritsy MC, Xu P, Gallant JC, Grace PS, Fenderson BA, Smith CM, Lindestam Arlehamn CS, Alter G, Lauffenburger DA, Sassetti CM. Noncanonical T cell responses are associated with protection from tuberculosis in mice and humans. J Exp Med. 2025 Jul 07; 222(7).

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Chang E, Cavallo K, Behar SM. CD4 T cell dysfunction is associated with bacterial recrudescence during chronic tuberculosis. Nat Commun. 2025 Mar 17; 16(1):2636.

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Simwela NV, Jaecklein E, Sassetti CM, Russell DG. Impaired fatty acid import or catabolism in macrophages restricts intracellular growth of Mycobacterium tuberculosis. Elife. 2025 Mar 13; 13.

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Oluoch PO, Koh EI, Proulx MK, Reames CJ, Papavinasasundaram KG, Murphy KC, Zimmerman MD, Dartois V, Sassetti CM. Chemical genetic interactions elucidate pathways controlling tuberculosis antibiotic efficacy during infection. Proc Natl Acad Sci U S A. 2025 Mar 04; 122(9):e2417525122.

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Pullen KM, Finethy R, Ko SB, Reames CJ, Sassetti CM, Lauffenburger DA. Cross-species transcriptomics translation reveals a role for the unfolded protein response in Mycobacterium tuberculosis infection. NPJ Syst Biol Appl. 2025 Feb 15; 11(1):19.

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Jaecklein E, Papavinasasundaram K, Ostroff GR, Sassetti C, Soto ER. Targeted delivery of antitubercular drugs using glucan lipid particles. Microbiol Spectr. 2025 Mar 04; 13(3):e0274424.

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Luna MJ, Oluoch PO, Miao J, Culviner P, Papavinasasundaram K, Jaecklein E, Shell SS, Ioerger TR, Fortune SM, Farhat MR, Sassetti CM. Frequently arising ESX-1-associated phase variants influence Mycobacterium tuberculosis fitness in the presence of host and antibiotic pressures. mBio. 2025 Mar 12; 16(3):e0376224.

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Zhao X, Di J, Luo D, Verma R, Verma SK, Verma S, Ravindar L, Koshle A, Dewangan HK, Gupta R, Chandra S, Deshpande S, Vaishnav Y, Rakesh KP. Thiazole - A promising scaffold for antituberculosis agents and structure-activity relationships studies. Bioorg Chem. 2025 Jan; 154:108035.

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Simwela NV, Johnston L, Bitar PP, Jaecklein E, Altier C, Sassetti CM, Russell DG. Genome-wide screen of Mycobacterium tuberculosis-infected macrophages revealed GID/CTLH complex-mediated modulation of bacterial growth. Nat Commun. 2024 Oct 29; 15(1):9322.

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