"Pyruvate Decarboxylase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Catalyzes the decarboxylation of an alpha keto acid to an aldehyde and carbon dioxide. Thiamine pyrophosphate is an essential cofactor. In lower organisms, which ferment glucose to ethanol and carbon dioxide, the enzyme irreversibly decarboxylates pyruvate to acetaldehyde. EC 4.1.1.1.
| Descriptor ID |
D011767
|
| MeSH Number(s) |
D08.811.520.224.125.750
|
| Concept/Terms |
Pyruvate Decarboxylase- Pyruvate Decarboxylase
- Decarboxylase, Pyruvate
- alpha-Carboxylase
- alpha Carboxylase
- Pyruvic Decarboxylase
- Decarboxylase, Pyruvic
- 2-Oxo Acid Carboxy-Lyase
- 2 Oxo Acid Carboxy Lyase
- Acid Carboxy-Lyase, 2-Oxo
- Carboxy-Lyase, 2-Oxo Acid
- alpha-Ketoacid Carboxylase
- Carboxylase, alpha-Ketoacid
- alpha Ketoacid Carboxylase
|
Below are MeSH descriptors whose meaning is more general than "Pyruvate Decarboxylase".
Below are MeSH descriptors whose meaning is more specific than "Pyruvate Decarboxylase".
This graph shows the total number of publications written about "Pyruvate Decarboxylase" by people in this website by year, and whether "Pyruvate Decarboxylase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 1 | 0 | 1 |
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Below are the most recent publications written about "Pyruvate Decarboxylase" by people in Profiles.
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Balakrishnan A, Gao Y, Moorjani P, Nemeria NS, Tittmann K, Jordan F. Bifunctionality of the thiamin diphosphate cofactor: assignment of tautomeric/ionization states of the 4'-aminopyrimidine ring when various intermediates occupy the active sites during the catalysis of yeast pyruvate decarboxylase. J Am Chem Soc. 2012 Feb 29; 134(8):3873-85.