 Receptors, Interleukin-4
"Receptors, Interleukin-4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Receptors present on a wide variety of hematopoietic and non-hematopoietic cell types that are specific for INTERLEUKIN-4. They are involved in signaling a variety of immunological responses related to allergic INFLAMMATION including the differentiation of TH2 CELLS and the regulation of IMMUNOGLOBULIN E production. Two subtypes of receptors exist and are referred to as the TYPE I INTERLEUKIN-4 RECEPTOR and the TYPE II INTERLEUKIN-4 RECEPTOR. Each receptor subtype is defined by its unique subunit composition.
| Descriptor ID |
D019948
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| MeSH Number(s) |
D12.776.543.750.705.852.420.360
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| Concept/Terms |
Receptors, Interleukin-4- Receptors, Interleukin-4
- Receptors, Interleukin 4
- B Cell-Activating Factor Receptor
- B Cell Activating Factor Receptor
- IL-4 Receptor
- IL 4 Receptor
- Receptor, IL-4
- Receptor, B Cell-Activating Factor
- Receptor, B Cell Activating Factor
- IL4 Receptor
- Receptor, IL4
- IL4 Receptors
- Receptors, IL4
- Interleukin 4 Receptor
- Receptor, Interleukin 4
- Interleukin-4 Receptors
- Interleukin 4 Receptors
- Receptors, IL-4
- Receptors, IL 4
- IL-4 Receptors
- IL 4 Receptors
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Below are MeSH descriptors whose meaning is more general than "Receptors, Interleukin-4".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Interleukin-4".
This graph shows the total number of publications written about "Receptors, Interleukin-4" by people in this website by year, and whether "Receptors, Interleukin-4" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1987 | 0 | 1 | 1 | | 1991 | 0 | 3 | 3 | | 1993 | 0 | 1 | 1 | | 1995 | 0 | 1 | 1 | | 1997 | 1 | 0 | 1 | | 1998 | 1 | 0 | 1 | | 2000 | 0 | 2 | 2 | | 2001 | 2 | 1 | 3 | | 2003 | 0 | 1 | 1 | | 2004 | 1 | 0 | 1 | | 2005 | 0 | 1 | 1 | | 2014 | 0 | 1 | 1 |
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Below are the most recent publications written about "Receptors, Interleukin-4" by people in Profiles.
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Huang SC, Everts B, Ivanova Y, O'Sullivan D, Nascimento M, Smith AM, Beatty W, Love-Gregory L, Lam WY, O'Neill CM, Yan C, Du H, Abumrad NA, Urban JF, Artyomov MN, Pearce EL, Pearce EJ. Cell-intrinsic lysosomal lipolysis is essential for alternative activation of macrophages. Nat Immunol. 2014 Sep; 15(9):846-55.
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Bernstein BE, Kamal M, Lindblad-Toh K, Bekiranov S, Bailey DK, Huebert DJ, McMahon S, Karlsson EK, Kulbokas EJ, Gingeras TR, Schreiber SL, Lander ES. Genomic maps and comparative analysis of histone modifications in human and mouse. Cell. 2005 Jan 28; 120(2):169-81.
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Zarlenga DS, Dawson H, Kringel H, Solano-Aguilar G, Urban JF. Molecular cloning of the swine IL-4 receptor alpha and IL-13 receptor 1-chains: effects of experimental Toxoplasma gondii, Ascaris suum and Trichuris suis infections on tissue mRNA levels. Vet Immunol Immunopathol. 2004 Oct; 101(3-4):223-34.
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Spencer L, Shultz L, Rajan TV. T cells are required for host protection against Brugia malayi but need not produce or respond to interleukin-4. Infect Immun. 2003 Jun; 71(6):3097-106.
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Spencer L, Shultz L, Rajan TV. Interleukin-4 receptor-Stat6 signaling in murine infections with a tissue-dwelling nematode parasite. Infect Immun. 2001 Dec; 69(12):7743-52.
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Urban JF, Noben-Trauth N, Schopf L, Madden KB, Finkelman FD. Cutting edge: IL-4 receptor expression by non-bone marrow-derived cells is required to expel gastrointestinal nematode parasites. J Immunol. 2001 Dec 01; 167(11):6078-81.
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Shea-Donohue T, Sullivan C, Finkelman FD, Madden KB, Morris SC, Goldhill J, Piñeiro-Carrero V, Urban JF. The role of IL-4 in Heligmosomoides polygyrus-induced alterations in murine intestinal epithelial cell function. J Immunol. 2001 Aug 15; 167(4):2234-9.
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Finkelman FD, Morris SC, Orekhova T, Mori M, Donaldson D, Reiner SL, Reilly NL, Schopf L, Urban JF. Stat6 regulation of in vivo IL-4 responses. J Immunol. 2000 Mar 01; 164(5):2303-10.
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Urban JF, Schopf L, Morris SC, Orekhova T, Madden KB, Betts CJ, Gamble HR, Byrd C, Donaldson D, Else K, Finkelman FD. Stat6 signaling promotes protective immunity against Trichinella spiralis through a mast cell- and T cell-dependent mechanism. J Immunol. 2000 Feb 15; 164(4):2046-52.
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Urban JF, Noben-Trauth N, Donaldson DD, Madden KB, Morris SC, Collins M, Finkelman FD. IL-13, IL-4Ralpha, and Stat6 are required for the expulsion of the gastrointestinal nematode parasite Nippostrongylus brasiliensis. Immunity. 1998 Feb; 8(2):255-64.
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