"Saquinavir" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An HIV protease inhibitor which acts as an analog of an HIV protease cleavage site. It is a highly specific inhibitor of HIV-1 and HIV-2 proteases, and also inhibits CYTOCHROME P-450 CYP3A.
| Descriptor ID |
D019258
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| MeSH Number(s) |
D03.633.100.531.770 D03.633.100.810.900
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Saquinavir".
Below are MeSH descriptors whose meaning is more specific than "Saquinavir".
This graph shows the total number of publications written about "Saquinavir" by people in this website by year, and whether "Saquinavir" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
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Below are the most recent publications written about "Saquinavir" by people in Profiles.
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Davis DA, Soule EE, Davidoff KS, Daniels SI, Naiman NE, Yarchoan R. Activity of human immunodeficiency virus type 1 protease inhibitors against the initial autocleavage in Gag-Pol polyprotein processing. Antimicrob Agents Chemother. 2012 Jul; 56(7):3620-8.
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Scribner AN, Troia-Cancio PV, Cox BA, Marcantonio D, Hamid F, Keiser P, Levi M, Allen B, Murphy K, Jones RE, Skiest DJ. Osteonecrosis in HIV: a case-control study. J Acquir Immune Defic Syndr. 2000 Sep 01; 25(1):19-25.