"Macrocyclic Compounds" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cyclic compounds with a ring size of approximately 1-4 dozen atoms.
| Descriptor ID |
D047028
|
| MeSH Number(s) |
D04.345
|
| Concept/Terms |
Macrocyclic Compounds- Macrocyclic Compounds
- Compounds, Macrocyclic
- Macrocycle Compounds
- Compounds, Macrocycle
|
Below are MeSH descriptors whose meaning is more general than "Macrocyclic Compounds".
Below are MeSH descriptors whose meaning is more specific than "Macrocyclic Compounds".
This graph shows the total number of publications written about "Macrocyclic Compounds" by people in this website by year, and whether "Macrocyclic Compounds" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2013 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2018 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Macrocyclic Compounds" by people in Profiles.
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Nageswara Rao D, Zephyr J, Henes M, Chan ET, Matthew AN, Hedger AK, Conway HL, Saeed M, Newton A, Petropoulos CJ, Huang W, Kurt Yilmaz N, Schiffer CA, Ali A. Discovery of Quinoxaline-Based P1-P3 Macrocyclic NS3/4A Protease Inhibitors with Potent Activity against Drug-Resistant Hepatitis C Virus Variants. J Med Chem. 2021 08 26; 64(16):11972-11989.
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Ibrahim M, Latif A, Ali A, Ribeiro AI, Farooq U, Ullah F, Khan A, Al-Harrasi A, Ahmad M, Ali M. Macrocyclic sulfone derivatives: Synthesis, characterization, in vitro biological evaluation and molecular docking. Drug Dev Res. 2021 06; 82(4):562-574.
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Abraham GM, Spooner LM. Citius, Altius, Fortius: The New Paradigm in the Treatment of Chronic Hepatitis C Disease. Clin Infect Dis. 2018 01 18; 66(3):464-474.
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Yan B, Yesilbag Tonga G, Hou S, Fedick PW, Yeh YC, Alfonso FS, Mizuhara T, Vachet RW, Rotello VM. Mass spectrometric detection of nanoparticle host-guest interactions in cells. Anal Chem. 2014 Jul 01; 86(13):6710-4.
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Ali A, Aydin C, Gildemeister R, Romano KP, Cao H, Ozen A, Soumana D, Newton A, Petropoulos CJ, Huang W, Schiffer CA. Evaluating the role of macrocycles in the susceptibility of hepatitis C virus NS3/4A protease inhibitors to drug resistance. ACS Chem Biol. 2013 Jul 19; 8(7):1469-78.
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Polshin V, Popescu DL, Fischer A, Chanda A, Horner DC, Beach ES, Henry J, Qian YL, Horwitz CP, Lente G, Fabian I, M?nck E, Bominaar EL, Ryabov AD, Collins TJ. Attaining control by design over the hydrolytic stability of Fe-TAML oxidation catalysts. J Am Chem Soc. 2008 Apr 02; 130(13):4497-506.
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O'Reilly CM, Fogarty KE, Drummond RM, Tuft RA, Walsh JV. Spontaneous mitochondrial depolarizations are independent of SR Ca2+ release. Am J Physiol Cell Physiol. 2004 May; 286(5):C1139-51.