Polymorphism, Single-Stranded Conformational
"Polymorphism, Single-Stranded Conformational" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Variation in a population's DNA sequence that is detected by determining alterations in the conformation of denatured DNA fragments. Denatured DNA fragments are allowed to renature under conditions that prevent the formation of double-stranded DNA and allow secondary structure to form in single stranded fragments. These fragments are then run through polyacrylamide gels to detect variations in the secondary structure that is manifested as an alteration in migration through the gels.
Descriptor ID |
D018807
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MeSH Number(s) |
G05.365.795.600
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Concept/Terms |
Polymorphism, Single-Stranded Conformational- Polymorphism, Single-Stranded Conformational
- Polymorphism, Single Stranded Conformational
- SSCP
- Single-Stranded Conformational Polymorphism
- Conformational Polymorphism, Single-Stranded
- Conformational Polymorphisms, Single-Stranded
- Polymorphisms, Single-Stranded Conformational
- Single Stranded Conformational Polymorphism
- Single-Stranded Conformational Polymorphisms
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Below are MeSH descriptors whose meaning is more general than "Polymorphism, Single-Stranded Conformational".
Below are MeSH descriptors whose meaning is more specific than "Polymorphism, Single-Stranded Conformational".
This graph shows the total number of publications written about "Polymorphism, Single-Stranded Conformational" by people in this website by year, and whether "Polymorphism, Single-Stranded Conformational" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1996 | 0 | 2 | 2 |
1997 | 0 | 1 | 1 |
1998 | 0 | 1 | 1 |
2000 | 0 | 3 | 3 |
2001 | 0 | 3 | 3 |
2002 | 1 | 1 | 2 |
2003 | 0 | 1 | 1 |
2004 | 1 | 1 | 2 |
2005 | 0 | 1 | 1 |
2006 | 1 | 0 | 1 |
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Below are the most recent publications written about "Polymorphism, Single-Stranded Conformational" by people in Profiles.
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Rashid MU, Zaidi A, Torres D, Sultan F, Benner A, Naqvi B, Shakoori AR, Seidel-Renkert A, Farooq H, Narod S, Amin A, Hamann U. Prevalence of BRCA1 and BRCA2 mutations in Pakistani breast and ovarian cancer patients. Int J Cancer. 2006 Dec 15; 119(12):2832-9.
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Agudelo-Fl?rez P, Prando-Andrade CC, L?pez JA, Costa-Carvalho BT, Quezada A, Espinosa FJ, de Souza Paiva MA, Roxo P, Grumach A, Jacob CA, Carneiro-Sampaio MM, Newburger PE, Condino-Neto A. Chronic granulomatous disease in Latin American patients: clinical spectrum and molecular genetics. Pediatr Blood Cancer. 2006 Feb; 46(2):243-52.
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Tyurina OV, Guner B, Popova E, Feng J, Schier AF, Kohtz JD, Karlstrom RO. Zebrafish Gli3 functions as both an activator and a repressor in Hedgehog signaling. Dev Biol. 2005 Jan 15; 277(2):537-56.
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Chen M, Deng A, Crowson AN, Srinivasan M, Yearsley KH, Jewell S, Morrison C, Long S, Werling R, Magro C. Assessment of T-cell clonality via T-cell receptor-gamma rearrangements in cutaneous T-cell-dominant infiltrates using polymerase chain reaction and single-stranded DNA conformational polymorphism assay. Appl Immunohistochem Mol Morphol. 2004 Dec; 12(4):373-9.
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Agudelo-Fl?rez P, Costa-Carvalho BT, L?pez JA, Redher J, Newburger PE, Olalla-Saad ST, Condino-Neto A. Association of glucose-6-phosphate dehydrogenase deficiency and X-linked chronic granulomatous disease in a child with anemia and recurrent infections. Am J Hematol. 2004 Mar; 75(3):151-6.
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Chen YY, Takita J, Chen YZ, Yang HW, Hanada R, Yamamoto K, Hayashi Y. Genomic structure and mutational analysis of the human KIF1Balpha gene located at 1p36.2 in neuroblastoma. Int J Oncol. 2003 Sep; 23(3):737-44.
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Shikanai T, Silverman ES, Morse BW, Lilly CM, Inoue H, Drazen JM. Sequence variants in the FcepsilonRI alpha chain gene. J Appl Physiol (1985). 2002 Jul; 93(1):37-41.
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Crisi GM, Emanuel JR, Johnson C, Crotty P, Costa J, Tallini G. Semireannealing, single-stranded conformational polymorphism: a novel and effective tool for the diagnosis of T-cell clonality. Diagn Mol Pathol. 2002 Jun; 11(2):67-74.
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Nakamura H, Luster AD, Nakamura T, In KH, Sonna LA, Deykin A, Israel E, Drazen JM, Lilly CM. Variant eotaxin: its effects on the asthma phenotype. J Allergy Clin Immunol. 2001 Dec; 108(6):946-53.
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Noack D, Heyworth PG, Newburger PE, Cross AR. An unusual intronic mutation in the CYBB gene giving rise to chronic granulomatous disease. Biochim Biophys Acta. 2001 Sep 28; 1537(2):125-31.