Bone Morphogenetic Protein 5
"Bone Morphogenetic Protein 5" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A bone morphogenetic protein that may play a role in CARTILAGE formation. It is a potent regulator of the growth of CHONDROCYTES and the synthesis of cartilage matrix proteins. Evidence for its role in cartilage formation can be seen in MICE, where genetic mutations that cause loss of bone morphogenetic protein 5 function result in the formation of small malformed ears.
Descriptor ID |
D055417
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MeSH Number(s) |
D12.644.276.954.200.500 D12.776.467.942.200.500 D23.529.942.200.500
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Bone Morphogenetic Protein 5".
Below are MeSH descriptors whose meaning is more specific than "Bone Morphogenetic Protein 5".
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Below are the most recent publications written about "Bone Morphogenetic Protein 5" by people in Profiles.
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Mailhot G, Yang M, Mason-Savas A, Mackay CA, Leav I, Odgren PR. BMP-5 expression increases during chondrocyte differentiation in vivo and in vitro and promotes proliferation and cartilage matrix synthesis in primary chondrocyte cultures. J Cell Physiol. 2008 Jan; 214(1):56-64.