"Photoaffinity Labels" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Biologically active molecules which are covalently bound to the enzymes or binding proteins normally acting on them. Binding occurs due to activation of the label by ultraviolet light. These labels are used primarily to identify binding sites on proteins.
| Descriptor ID |
D019920
|
| MeSH Number(s) |
D27.720.470.410.080.600
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Photoaffinity Labels".
Below are MeSH descriptors whose meaning is more specific than "Photoaffinity Labels".
This graph shows the total number of publications written about "Photoaffinity Labels" by people in this website by year, and whether "Photoaffinity Labels" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2002 | 0 | 2 | 2 |
| 2008 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
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Below are the most recent publications written about "Photoaffinity Labels" by people in Profiles.
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Kotoku N, Nakata C, Kawachi T, Sato T, Guo XH, Ito A, Sumii Y, Arai M, Kobayashi M. Synthesis and evaluation of effective photoaffinity probe molecule of furospinosulin-1, a hypoxia-selective growth inhibitor. Bioorg Med Chem. 2014 Apr 01; 22(7):2102-12.
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Wittelsberger A, Mierke DF, Rosenblatt M. Mapping ligand-receptor interfaces: approaching the resolution limit of benzophenone-based photoaffinity scanning. Chem Biol Drug Des. 2008 Apr; 71(4):380-3.
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Carraway RE, Gui X, Cochrane DE. Ca2+ channel blockers enhance neurotensin (NT) binding and inhibit NT-induced inositol phosphate formation in prostate cancer PC3 cells. J Pharmacol Exp Ther. 2003 Nov; 307(2):640-50.
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Cloherty EK, Levine KB, Graybill C, Carruthers A. Cooperative nucleotide binding to the human erythrocyte sugar transporter. Biochemistry. 2002 Oct 22; 41(42):12639-51.
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Levine KB, Cloherty EK, Hamill S, Carruthers A. Molecular determinants of sugar transport regulation by ATP. Biochemistry. 2002 Oct 22; 41(42):12629-38.
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Bhat N, Perera PY, Carboni JM, Blanco J, Golenbock DT, Mayadas TN, Vogel SN. Use of a photoactivatable taxol analogue to identify unique cellular targets in murine macrophages: identification of murine CD18 as a major taxol-binding protein and a role for Mac-1 in taxol-induced gene expression. J Immunol. 1999 Jun 15; 162(12):7335-42.