"Bone Remodeling" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The continuous turnover of BONE MATRIX and mineral that involves first an increase in BONE RESORPTION (osteoclastic activity) and later, reactive BONE FORMATION (osteoblastic activity). The process of bone remodeling takes place in the adult skeleton at discrete foci. The process ensures the mechanical integrity of the skeleton throughout life and plays an important role in calcium HOMEOSTASIS. An imbalance in the regulation of bone remodeling's two contrasting events, bone resorption and bone formation, results in many of the metabolic bone diseases, such as OSTEOPOROSIS.
| Descriptor ID |
D016723
|
| MeSH Number(s) |
G11.427.213 G16.762.150
|
| Concept/Terms |
Bone Remodeling- Bone Remodeling
- Remodeling, Bone
- Bone Turnover
- Bone Turnovers
- Turnover, Bone
- Turnovers, Bone
|
Below are MeSH descriptors whose meaning is more general than "Bone Remodeling".
Below are MeSH descriptors whose meaning is more specific than "Bone Remodeling".
This graph shows the total number of publications written about "Bone Remodeling" by people in this website by year, and whether "Bone Remodeling" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 0 | 1 |
| 1999 | 0 | 1 | 1 |
| 2001 | 1 | 0 | 1 |
| 2005 | 0 | 1 | 1 |
| 2008 | 0 | 3 | 3 |
| 2009 | 1 | 2 | 3 |
| 2010 | 1 | 0 | 1 |
| 2011 | 2 | 1 | 3 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2015 | 0 | 3 | 3 |
| 2020 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Bone Remodeling" by people in Profiles.
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Park Y, Cheong E, Kwak JG, Carpenter R, Shim JH, Lee J. Trabecular bone organoid model for studying the regulation of localized bone remodeling. Sci Adv. 2021 01; 7(4).
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Kim JM, Lin C, Stavre Z, Greenblatt MB, Shim JH. Osteoblast-Osteoclast Communication and Bone Homeostasis. Cells. 2020 09 10; 9(9).
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Baum R, Gravallese EM. Bone as a Target Organ in Rheumatic Disease: Impact on Osteoclasts and Osteoblasts. Clin Rev Allergy Immunol. 2016 Aug; 51(1):1-15.
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Scanlon V, Soung do Y, Adapala NS, Morgan E, Hansen MF, Drissi H, Sanjay A. Role of Cbl-PI3K Interaction during Skeletal Remodeling in a Murine Model of Bone Repair. PLoS One. 2015; 10(9):e0138194.
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Lian JB. Epigenetic pathways regulating bone homeostasis. Bone. 2015 Dec; 81:731-732.
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Nam J, Perera P, Gordon R, Jeong YH, Blazek AD, Kim DG, Tee BC, Sun Z, Eubank TD, Zhao Y, Lablebecioglu B, Liu S, Litsky A, Weisleder NL, Lee BS, Butterfield T, Schneyer AL, Agarwal S. Follistatin-like 3 is a mediator of exercise-driven bone formation and strengthening. Bone. 2015 Sep; 78:62-70.
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Bhutani M, Landgren O, Usmani SZ. Multiple myeloma: is it time for biomarker-driven therapy? Am Soc Clin Oncol Educ Book. 2015; e493-503.
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Gaddini GW, Grant KA, Woodall A, Stull C, Maddalozzo GF, Zhang B, Turner RT, Iwaniec UT. Twelve months of voluntary heavy alcohol consumption in male rhesus macaques suppresses intracortical bone remodeling. Bone. 2015 Feb; 71:227-36.
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Clifton KB, Paglia DN, Soung do Y, Wolf JM, Moss IL, Drissi H. Effects of Wnt5a Haploinsufficiency on Bone Repair. J Orthop Trauma. 2014 Aug; 28(8):e191-7.
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Gentile MA, Soung do Y, Horrell C, Samadfam R, Drissi H, Duong LT. Increased fracture callus mineralization and strength in cathepsin K knockout mice. Bone. 2014 Sep; 66:72-81.