 Bone Remodeling
"Bone Remodeling" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The continuous turnover of bone matrix and mineral that involves first, an increase in resorption (osteoclastic activity) and later, reactive bone formation (osteoblastic activity). The process of bone remodeling takes place in the adult skeleton at discrete foci. The process ensures the mechanical integrity of the skeleton throughout life and plays an important role in calcium homeostasis. An imbalance in the regulation of bone remodeling's two contrasting events, bone resorption and bone formation, results in many of the metabolic bone diseases, such as OSTEOPOROSIS.
| Descriptor ID |
D016723
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| MeSH Number(s) |
G11.427.590.195 G16.100.856.150
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Bone Remodeling".
Below are MeSH descriptors whose meaning is more specific than "Bone Remodeling".
This graph shows the total number of publications written about "Bone Remodeling" by people in this website by year, and whether "Bone Remodeling" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 | | 1997 | 1 | 0 | 1 | | 1998 | 1 | 0 | 1 | | 1999 | 0 | 2 | 2 | | 2000 | 1 | 0 | 1 | | 2001 | 1 | 0 | 1 | | 2005 | 0 | 2 | 2 | | 2008 | 0 | 3 | 3 | | 2009 | 1 | 2 | 3 | | 2010 | 2 | 0 | 2 | | 2011 | 2 | 1 | 3 | | 2012 | 0 | 1 | 1 | | 2013 | 0 | 1 | 1 | | 2014 | 1 | 0 | 1 | | 2015 | 0 | 2 | 2 |
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Below are the most recent publications written about "Bone Remodeling" by people in Profiles.
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Scanlon V, Soung do Y, Adapala NS, Morgan E, Hansen MF, Drissi H, Sanjay A. Role of Cbl-PI3K Interaction during Skeletal Remodeling in a Murine Model of Bone Repair. PLoS One. 2015; 10(9):e0138194.
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Lian JB. Epigenetic pathways regulating bone homeostasis. Bone. 2015 Dec; 81:731-2.
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Bhutani M, Landgren O, Usmani SZ. Multiple myeloma: is it time for biomarker-driven therapy? Am Soc Clin Oncol Educ Book. 2015; e493-503.
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Gaddini GW, Grant KA, Woodall A, Stull C, Maddalozzo GF, Zhang B, Turner RT, Iwaniec UT. Twelve months of voluntary heavy alcohol consumption in male rhesus macaques suppresses intracortical bone remodeling. Bone. 2015 Feb; 71:227-36.
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Clifton KB, Paglia DN, Soung do Y, Wolf JM, Moss IL, Drissi H. Effects of Wnt5a Haploinsufficiency on Bone Repair. J Orthop Trauma. 2014 Aug; 28(8):e191-7.
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Gentile MA, Soung do Y, Horrell C, Samadfam R, Drissi H, Duong LT. Increased fracture callus mineralization and strength in cathepsin K knockout mice. Bone. 2014 Sep; 66:72-81.
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Baum R, Gravallese EM. Impact of inflammation on the osteoblast in rheumatic diseases. Curr Osteoporos Rep. 2014 Mar; 12(1):9-16.
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van Wijnen AJ, van de Peppel J, van Leeuwen JP, Lian JB, Stein GS, Westendorf JJ, Oursler MJ, Im HJ, Taipaleenmäki H, Hesse E, Riester S, Kakar S. MicroRNA functions in osteogenesis and dysfunctions in osteoporosis. Curr Osteoporos Rep. 2013 Jun; 11(2):72-82.
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Soung do Y, Gentile MA, Duong LT, Drissi H. Effects of pharmacological inhibition of cathepsin K on fracture repair in mice. Bone. 2013 Jul; 55(1):248-55.
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Sun Y, Byon CH, Yuan K, Chen J, Mao X, Heath JM, Javed A, Zhang K, Anderson PG, Chen Y. Smooth muscle cell-specific runx2 deficiency inhibits vascular calcification. Circ Res. 2012 Aug 17; 111(5):543-52.
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