Crohn Disease

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"Crohn Disease" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A chronic transmural inflammation that may involve any part of the DIGESTIVE TRACT from MOUTH to ANUS, mostly found in the ILEUM, the CECUM, and the COLON. In Crohn disease, the inflammation, extending through the intestinal wall from the MUCOSA to the serosa, is characteristically asymmetric and segmental. Epithelioid GRANULOMAS may be seen in some patients.

Descriptor ID	D003424
MeSH Number(s)	C06.405.205.731.500 C06.405.469.432.500
Concept/Terms	Crohn Disease Crohn Disease Crohn's Enteritis Regional Enteritis Crohn's Disease Crohns Disease Inflammatory Bowel Disease 1 Enteritis, Granulomatous Enteritis, Granulomatous Granulomatous Enteritis Enteritis, Regional Ileocolitis Ileocolitis Colitis, Granulomatous Colitis, Granulomatous Granulomatous Colitis Ileitis, Terminal Ileitis, Terminal Terminal Ileitis Ileitis, Regional Regional Ileitides Regional Ileitis

Below are MeSH descriptors whose meaning is more general than "Crohn Disease".

Diseases [C]
Digestive System Diseases [C06]
Gastrointestinal Diseases [C06.405]
Gastroenteritis [C06.405.205]
Inflammatory Bowel Diseases [C06.405.205.731]
Crohn Disease [C06.405.205.731.500]
Intestinal Diseases [C06.405.469]
Inflammatory Bowel Diseases [C06.405.469.432]
Crohn Disease [C06.405.469.432.500]

Below are MeSH descriptors whose meaning is related to "Crohn Disease".

Below are MeSH descriptors whose meaning is more specific than "Crohn Disease".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Crohn Disease" by people in this website by year, and whether "Crohn Disease" was a major or minor topic of these publications.

Bar chart showing 81 publications over 23 distinct years, with a maximum of 8 publications in 2014

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	1	0	1
2002	1	1	2
2003	1	1	2
2004	1	2	3
2006	2	0	2
2007	1	2	3
2008	1	0	1
2009	3	1	4
2010	4	1	5
2011	1	1	2
2012	3	1	4
2013	1	0	1
2014	6	2	8
2015	2	0	2
2016	3	1	4
2017	5	1	6
2018	1	1	2
2019	2	0	2
2020	5	1	6
2021	5	2	7
2022	5	0	5
2023	3	0	3
2024	6	0	6

Below are the most recent publications written about "Crohn Disease" by people in Profiles.

Cleveland NK, Ghosh S, Kathe N, Umashankar K, Mirchandani K, Hait A, Paul R, Candela N, Fan T, Rubin DT. Dose escalation of biologics in biologic-naive patients with Crohn's disease: Outcomes from the ODESSA-CD study. J Manag Care Spec Pharm. 2024 Nov; 30(11):1276-1287.

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Krugliak Cleveland N, Ghosh S, Chastek B, Bancroft T, Candela N, Fan T, Umashankar K, Rubin DT. Real-World Persistence of Successive Biologics in Patients With Inflammatory Bowel Disease: Findings From ROTARY. Inflamm Bowel Dis. 2024 Oct 03; 30(10):1776-1787.

View in: PubMed
Krugliak Cleveland N, Ghosh S, Chastek B, Bancroft T, Candela N, Fan T, Umashankar K, Rubin DT. Evaluation of adverse clinical outcomes in patients with inflammatory bowel disease receiving different sequences of first- and second-line biologic treatments: findings from ROTARY. BMC Gastroenterol. 2024 Sep 17; 24(1):314.

View in: PubMed
McKenna NP, Bews KA, Mirande MD, Abarca Rendon FM, Ofshteyn A, Peponis T, Shawki SF, Kelley SR, Mathis KL. Surgical management of duodenal crohn's disease. Langenbecks Arch Surg. 2024 Apr 19; 409(1):132.

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Chiorean M, Jiang J, Candela N, Chen G, Romdhani H, Latremouille-Viau D, Shi S, Bungay R, Guerin A, Fan T. Real-world clinical outcomes and healthcare costs in patients with Crohn's disease treated with vedolizumab versus ustekinumab in the United States. Curr Med Res Opin. 2024 05; 40(5):877-885.

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Bonifacio C, Savini G, Reca C, Garoli F, Levi R, Vatteroni G, Balzarini L, Allocca M, Furfaro F, Dal Buono A, Armuzzi A, Danese S, Matteoli M, Rescigno M, Fiorino G, Politi LS. The gut-brain axis: Correlation of choroid plexus volume and permeability with inflammatory biomarkers in Crohn's disease. Neurobiol Dis. 2024 Mar; 192:106416.

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Kay J, Cross RK, Feldman SR, Park Y, Hanauer SB. Review of Adalimumab Biosimilar SB5 in Immune-Mediated Inflammatory Diseases. Adv Ther. 2024 02; 41(2):509-533.

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Vu M, Ghosh S, Umashankar K, Weber L, Landis C, Candela N, Chastek B. Comparison of surgery rates in biologic-na?ve patients with Crohn's disease treated with vedolizumab or ustekinumab: findings from SOJOURN. BMC Gastroenterol. 2023 Mar 25; 23(1):87.

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Kaplan JL, Liu C, King EC, Bass JA, Patel AS, Tung J, Chen S, Lissoos T, Candela N, Saeed S, Colletti RB. Use, Durability, and Risks for Discontinuation of Initial and Subsequent Biologics in a Large Pediatric-Onset IBD Cohort. J Pediatr Gastroenterol Nutr. 2023 05 01; 76(5):566-575.

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Fraschilla I, Amatullah H, Rahman RU, Jeffrey KL. Immune chromatin reader SP140 regulates microbiota and risk for inflammatory bowel disease. Cell Host Microbe. 2022 10 12; 30(10):1370-1381.e5.

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