Hemophilia A

"Hemophilia A" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The classic hemophilia resulting from a deficiency of factor VIII. It is an inherited disorder of blood coagulation characterized by a permanent tendency to hemorrhage.

Descriptor ID	D006467
MeSH Number(s)	C15.378.100.100.500 C15.378.100.141.500 C15.378.463.500 C16.320.099.500
Concept/Terms	Hemophilia A Hemophilia A Hemophilia As Hemophilia, Classic Hemophilia Hemophilia A, Congenital Congenital Hemophilia A Congenital Hemophilia As Hemophilia As, Congenital Classic Hemophilia Classic Hemophilias Hemophilias, Classic Haemophilia Autosomal Hemophilia A Autosomal Hemophilia A As, Autosomal Hemophilia Autosomal Hemophilia As Hemophilia A, Autosomal Hemophilia As, Autosomal Factor VIII Deficiency Factor VIII Deficiency Factor 8 Deficiency, Congenital Factor VIII Deficiency, Congenital Deficiency, Factor VIII

Below are MeSH descriptors whose meaning is more general than "Hemophilia A".

Diseases [C]
Hemic and Lymphatic Diseases [C15]
Hematologic Diseases [C15.378]
Blood Coagulation Disorders [C15.378.100]
Blood Coagulation Disorders, Inherited [C15.378.100.100]
Hemophilia A [C15.378.100.100.500]
Coagulation Protein Disorders [C15.378.100.141]
Hemophilia A [C15.378.100.141.500]
Hemorrhagic Disorders [C15.378.463]
Hemophilia A [C15.378.463.500]
Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]
Genetic Diseases, Inborn [C16.320]
Blood Coagulation Disorders, Inherited [C16.320.099]
Hemophilia A [C16.320.099.500]

Below are MeSH descriptors whose meaning is related to "Hemophilia A".

Below are MeSH descriptors whose meaning is more specific than "Hemophilia A".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Hemophilia A" by people in this website by year, and whether "Hemophilia A" was a major or minor topic of these publications.

Bar chart showing 17 publications over 10 distinct years, with a maximum of 4 publications in 1996

To see the data from this visualization as text, click here.

Year	Major Topic	Total
1995	2	2
1996	4	4
1999	1	1
2000	1	1
2001	2	2
2005	1	1
2011	1	1
2014	1	1
2019	2	2
2022	2	2

Below are the most recent publications written about "Hemophilia A" by people in Profiles.

Joo JH, Wang X, Singh S, Chen CY, Li C, Adair JE, Kiem HP, Rawlings DJ, Miao CH. Intraosseous delivery of platelet-targeted factor VIII lentiviral vector in humanized NBSGW mice. Blood Adv. 2022 10 11; 6(19):5556-5569.

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Latef TJ, Bhardwaj P, Bilal M. Refractory acquired haemophilia A in a patient with HIV treated with Emicizumab. Blood Coagul Fibrinolysis. 2022 Mar 01; 33(2):138-140.

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Croteau SE, Frelinger AL, Gerrits AJ, Michelson AD. Decreased platelet surface phosphatidylserine predicts increased bleeding in patients with severe factor VIII deficiency. J Thromb Haemost. 2021 04; 19(4):976-982.

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Gundabolu K, Goldsweig A, Bhatt VR, Koepsell SA, Harper JL. ST-Segment Elevation Myocardial Infarction (STEMI) and Pulmonary Embolism in a Hemophilia A Patient Receiving Emicizumab and recombinant Activated Factor VII. Haemophilia. 2020 Jan; 26(1):e5-e8.

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Chang IJ, Byers HM, Ng BG, Merritt JL, Gilmore R, Shrimal S, Wei W, Zhang Y, Blair AB, Freeze HH, Zhang B, Lam C. Factor VIII and vWF deficiency in STT3A-CDG. J Inherit Metab Dis. 2019 03; 42(2):325-332.

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Boylan B, Rice AS, Dunn AL, Tarantino MD, Brettler DB, Barrett JC, Miller CH. Characterization of the anti-factor VIII immunoglobulin profile in patients with hemophilia A by use of a fluorescence-based immunoassay. J Thromb Haemost. 2015 Jan; 13(1):47-53.

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Muzaffar J, Katragadda L, Haider S, Javed A, Anaissie E, Usmani S. Rituximab and intravenous immunoglobulin (IVIG) for the management of acquired factor VIII inhibitor in multiple myeloma: case report and review of literature. Int J Hematol. 2012 Jan; 95(1):102-6.

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Brettler DB. Gene therapy for hemophilia? J Thromb Haemost. 2005 Jun; 3(6):1317-9.

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Qin H, Shire NJ, Keenan ED, Rouster SD, Eyster ME, Goedert JJ, Koziel MJ, Sherman KE. HCV quasispecies evolution: association with progression to end-stage liver disease in hemophiliacs infected with HCV or HCV/HIV. Blood. 2005 Jan 15; 105(2):533-41.

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Xu L, Daly T, Gao C, Flotte TR, Song S, Byrne BJ, Sands MS, Parker Ponder K. CMV-beta-actin promoter directs higher expression from an adeno-associated viral vector in the liver than the cytomegalovirus or elongation factor 1 alpha promoter and results in therapeutic levels of human factor X in mice. Hum Gene Ther. 2001 Mar 20; 12(5):563-73.

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