Adipose Tissue, Brown

"Adipose Tissue, Brown" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A thermogenic form of adipose tissue composed of BROWN ADIPOCYTES. It is found in newborns of many species including humans, and in hibernating mammals. Brown fat is richly vascularized, innervated, and densely packed with MITOCHONDRIA which can generate heat directly from the stored lipids.

Descriptor ID	D002001
MeSH Number(s)	A10.165.114.322
Concept/Terms	Adipose Tissue, Brown Adipose Tissue, Brown Tissue, Brown Adipose Brown Adipose Tissue Brown Fat Fat, Brown Hibernating Gland Hibernating Gland

Below are MeSH descriptors whose meaning is more general than "Adipose Tissue, Brown".

Anatomy [A]
Tissues [A10]
Connective Tissue [A10.165]
Adipose Tissue [A10.165.114]
Adipose Tissue, Brown [A10.165.114.322]

Below are MeSH descriptors whose meaning is related to "Adipose Tissue, Brown".

Below are MeSH descriptors whose meaning is more specific than "Adipose Tissue, Brown".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Adipose Tissue, Brown" by people in this website by year, and whether "Adipose Tissue, Brown" was a major or minor topic of these publications.

Bar chart showing 75 publications over 18 distinct years, with a maximum of 8 publications in 2017 and 2024

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2003	0	2	2
2007	1	1	2
2009	2	1	3
2011	2	0	2
2012	1	1	2
2013	3	0	3
2014	1	1	2
2015	3	2	5
2016	2	2	4
2017	5	3	8
2018	3	1	4
2019	4	1	5
2020	1	5	6
2021	3	0	3
2022	3	4	7
2023	3	1	4
2024	6	2	8
2025	2	3	5

Below are the most recent publications written about "Adipose Tissue, Brown" by people in Profiles.

Zhao C, Zhan M, Du H, Zhu K, Chen S, Song M, Cao Y, Xiao H. Impact of Citrus Pectin on Gut Microbiota Metabolism Dysbiosis Induced by Transient Alternating High-Fat Diet. J Agric Food Chem. 2025 Aug 20; 73(33):20888-20899.

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Brown DE, Shreyer S, Witkowski S, Sievert LL. Brown Adipose Tissue, Adiposity, and Menopausal Status in Women at Mid-Life. Am J Biol Anthropol. 2025 Jun; 187(2):e70073.

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Fern?ndez-Gonz?lez I, Freire-Agulleiro O, Ferreira V, Silveira-Loureiro M, Rial-Pensado E, Garrido-Gil P, Mart?nez G, Rada P, Labandeira-Garc?a JL, Mittag J, Gonz?lez-Garc?a I, Di?guez C, Nogueiras R, Valverde ?M, Davis RJ, Sabio G, Barca-Mayo O, L?pez M. JNK1 in SF1 neurons regulates the central action of thyroid hormones on hepatic lipid metabolism. Mol Metab. 2025 Aug; 98:102170.

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Agueda-Oyarzabal M, Isidor MS, Plucinska K, Ingerslev LR, Dmytriyeva O, Petersen PSS, Laftih S, Pontoppidan AB, Henningsen JB, Rupar K, Brown EL, Schwartz TW, Barr?s R, Gerhart-Hines Z, Sch?ele CC, Emanuelli B. Transcriptomic signatures of cold acclimated adipocytes reveal CXCL12 as a Brown autocrine and paracrine chemokine. Mol Metab. 2025 Mar; 93:102102.

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Cicu?ndez B, Mora A, L?pez JA, Curtabbi A, P?rez-Garc?a J, Porteiro B, Jimenez-Blasco D, Latorre-Muro P, Vo P, Jerome M, G?mez-Santos B, Romero-Becerra R, Leiva M, Rodr?guez E, Le?n M, Leiva-Vega L, G?mez-Lado N, Torres JL, Hern?ndez-Cosido L, Aguiar P, Marcos M, Jastroch M, Daiber A, Aspichueta P, Bola?os JP, Spinelli JB, Puigserver P, Enriquez JA, V?zquez J, Folgueira C, Sabio G. Absence of MCJ/DnaJC15 promotes brown adipose tissue thermogenesis. Nat Commun. 2025 01 13; 16(1):229.

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Valdecantos MP, Ruiz L, Folgueira C, Rada P, Gomez-Santos B, Solas M, Hitos AB, Field J, Francisco V, Escalona-Garrido C, Zagmutt S, Calderon-Dominguez M, Mera P, Garcia-Martinez I, Maym?-Masip E, Grajales D, Alen R, Mora A, S?inz N, Vides-Urrestarazu I, Vilarrasa N, Arbones-Mainar JM, Zaragoza C, Moreno-Aliaga MJ, Aspichueta P, Fern?ndez-Veledo S, Vendrell J, Serra D, Herrero L, Schreiber R, Zechner R, Sabio G, Hornigold D, Rondinone CM, Jermutus L, Grimsby J, Valverde ?M. The dual GLP-1/glucagon receptor agonist G49 mimics bariatric surgery effects by inducing metabolic rewiring and inter-organ crosstalk. Nat Commun. 2024 11 28; 15(1):10342.

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Korobkina ED, Calejman CM, Haley JA, Kelly ME, Li H, Gaughan M, Chen Q, Pepper HL, Ahmad H, Boucher A, Fluharty SM, Lin TY, Lotun A, Peura J, Trefely S, Green CR, Vo P, Semenkovich CF, Pitarresi JR, Spinelli JB, Aydemir O, Metallo CM, Lynes MD, Jang C, Snyder NW, Wellen KE, Guertin DA. Brown fat ATP-citrate lyase links carbohydrate availability to thermogenesis and guards against metabolic stress. Nat Metab. 2024 Nov; 6(11):2187-2202.

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Shin YC, Latorre-Muro P, Djurabekova A, Zdorevskyi O, Bennett CF, Burger N, Song K, Xu C, Paulo JA, Gygi SP, Sharma V, Liao M, Puigserver P. Structural basis of respiratory complex adaptation to cold temperatures. Cell. 2024 Nov 14; 187(23):6584-6598.e17.

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Sievert LL, Shreyer S, Witkowski S, Brown DE. Brown Adipose Tissue Activity and Childhood Exposure to Cold Are Associated With Hot Flashes at Menopause. Am J Hum Biol. 2024 Nov; 36(11):e24148.

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Nomura K, Kinoshita S, Mizusaki N, Senga Y, Sasaki T, Kitamura T, Sakaue H, Emi A, Hosooka T, Matsuo M, Okamura H, Amo T, Wolf AM, Kamimura N, Ohta S, Itoh T, Hayashi Y, Kiyonari H, Krook A, Zierath JR, Kasuga M, Ogawa W. Adaptive gene expression of alternative splicing variants of PGC-1a regulates whole-body energy metabolism. Mol Metab. 2024 Aug; 86:101968.

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