Mitral Valve Prolapse

"Mitral Valve Prolapse" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Abnormal protrusion or billowing of one or both of the leaflets of MITRAL VALVE into the LEFT ATRIUM during SYSTOLE. This allows the backflow of blood into left atrium leading to MITRAL VALVE INSUFFICIENCY; SYSTOLIC MURMURS; or CARDIAC ARRHYTHMIA.

Descriptor ID	D008945
MeSH Number(s)	C14.280.484.400.500
Concept/Terms	Mitral Valve Prolapse Mitral Valve Prolapse Mitral Valve Prolapses Prolapse, Mitral Valve Prolapses, Mitral Valve Valve Prolapse, Mitral Valve Prolapses, Mitral Floppy Mitral Valve Floppy Mitral Valves Mitral Valve, Floppy Mitral Valves, Floppy Mitral Click-Murmur Syndrome Click-Murmur Syndrome, Mitral Mitral Click Murmur Syndrome Syndrome, Mitral Click-Murmur Systolic Click-Murmur Syndrome Click-Murmur Syndrome, Systolic Syndrome, Systolic Click-Murmur Systolic Click Murmur Syndrome Prolapsed Mitral Valve Mitral Valve, Prolapsed Mitral Valves, Prolapsed Prolapsed Mitral Valves Valve, Prolapsed Mitral Valves, Prolapsed Mitral Click-Murmur Syndrome Click Murmur Syndrome Click-Murmur Syndromes Syndrome, Click-Murmur Syndromes, Click-Murmur Mitral Valve Prolapse Syndrome

Below are MeSH descriptors whose meaning is more general than "Mitral Valve Prolapse".

Diseases [C]
Cardiovascular Diseases [C14]
Heart Diseases [C14.280]
Heart Valve Diseases [C14.280.484]
Heart Valve Prolapse [C14.280.484.400]
Mitral Valve Prolapse [C14.280.484.400.500]

Below are MeSH descriptors whose meaning is related to "Mitral Valve Prolapse".

Below are MeSH descriptors whose meaning is more specific than "Mitral Valve Prolapse".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Mitral Valve Prolapse" by people in this website by year, and whether "Mitral Valve Prolapse" was a major or minor topic of these publications.

Bar chart showing 6 publications over 5 distinct years, with a maximum of 2 publications in 2016

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2005	1	0	1
2011	1	0	1
2016	1	1	2
2021	1	0	1
2024	1	0	1

Below are the most recent publications written about "Mitral Valve Prolapse" by people in Profiles.

Harris KM, Mackey-Bojack S, Fisher G, Nwaudo D, Maron BJ. Arrhythmogenic Mitral Valve Prolapse Revisited: A Not Uncommon Cause of Youthful Sudden Death in Athletes and Women. Am J Med. 2025 Jan; 138(1):156-160.

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Wilkie GL, Qureshi WT, O'Day KW, Aurigemma GP, Goldberg RJ, Amjad W, Alqalyoobi S, Kakouros N, Lauring JR, Leftwich HK, Harrington CM. Cardiac and Obstetric Outcomes Associated With Mitral Valve Prolapse. Am J Cardiol. 2022 01 01; 162:150-155.

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Greenhouse DG, Murphy A, Mignatti P, Zavadil J, Galloway AC, Balsam LB. Mitral valve prolapse is associated with altered extracellular matrix gene expression patterns. Gene. 2016 Jul 15; 586(1):56-61.

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Maron BJ, Haas TS, Ahluwalia A, Murphy CJ, Garberich RF. Demographics and Epidemiology of Sudden Deaths in Young Competitive Athletes: From the United States National Registry. Am J Med. 2016 Nov; 129(11):1170-1177.

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Delling FN, Gona P, Larson MG, Lehman B, Manning WJ, Levine RA, Benjamin EJ, Vasan RS. Mild expression of mitral valve prolapse in the Framingham offspring: expanding the phenotypic spectrum. J Am Soc Echocardiogr. 2014 Jan; 27(1):17-23.

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Hashim SW, Youssef SJ, Ayyash B, Rousou AJ, Ragnarsson S, Collazo S, Geirsson A. Pseudoprolapse of the anterior leaflet in chronic ischemic mitral regurgitation: identification and repair. J Thorac Cardiovasc Surg. 2012 Apr; 143(4 Suppl):S33-7.

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Nishimura RA, Carabello BA, Faxon DP, Freed MD, Lytle BW, O'Gara PT, O'Rourke RA, Shah PM, Bonow RO, Carabello BA, Chatterjee K, de Leon AC, Faxon DP, Freed MD, Gaasch WH, Lytle BW, Nishimura RA, O'Gara PT, O'Rourke RA, Otto CM, Shah PM, Shanewise JS, Smith SC, Jacobs AK, Buller CE, Creager MA, Ettinger SM, Krumholz HM, Kushner FG, Lytle BW, Nishimura RA, Page RL, Tarkington LG, Yancy CW. ACC/AHA 2008 guideline update on valvular heart disease: focused update on infective endocarditis: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines endorsed by the Society of Cardiovascular Anesthesiologists, Society for Cardiovascular Angiography and Interventions, and Society of Thoracic Surgeons. Catheter Cardiovasc Interv. 2008 Sep 01; 72(3):E1-E12.

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Bonow RO, Carabello BA, Kanu C, de Leon AC, Faxon DP, Freed MD, Gaasch WH, Lytle BW, Nishimura RA, O'Gara PT, O'Rourke RA, Otto CM, Shah PM, Shanewise JS, Smith SC, Jacobs AK, Adams CD, Anderson JL, Antman EM, Faxon DP, Fuster V, Halperin JL, Hiratzka LF, Hunt SA, Lytle BW, Nishimura R, Page RL, Riegel B. ACC/AHA 2006 guidelines for the management of patients with valvular heart disease: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (writing committee to revise the 1998 Guidelines for the Management of Patients With Valvular Heart Disease): developed in collaboration with the Society of Cardiovascular Anesthesiologists: endorsed by the Society for Cardiovascular Angiography and Interventions and the Society of Thoracic Surgeons. Circulation. 2006 Aug 01; 114(5):e84-231.

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Maron BJ, Ackerman MJ, Nishimura RA, Pyeritz RE, Towbin JA, Udelson JE. Task Force 4: HCM and other cardiomyopathies, mitral valve prolapse, myocarditis, and Marfan syndrome. J Am Coll Cardiol. 2005 Apr 19; 45(8):1340-5.

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Spodick DH, Pezzella AT. Images in clinical medicine. A grade 6 systolic murmur. N Engl J Med. 1999 Jul 01; 341(1):27.

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