 Factor XI Deficiency
"Factor XI Deficiency" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A hereditary deficiency of blood coagulation factor XI (also known as plasma thromboplastin antecedent or PTA or antihemophilic factor C) resulting in a systemic blood-clotting defect called hemophilia C or Rosenthal's syndrome, that may resemble classical hemophilia.
| Descriptor ID |
D005173
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| MeSH Number(s) |
C15.378.100.100.325 C15.378.100.141.325 C15.378.463.325 C16.320.099.325
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| Concept/Terms |
Factor XI Deficiency- Factor XI Deficiency
- Deficiencies, Factor XI
- Factor XI Deficiencies
- Rosenthal's Syndrome
- Rosenthal's Syndromes
- Rosenthals Syndrome
- Syndrome, Rosenthal's
- Plasma Thromboplastin Antecedent Deficiency
- Rosenthal Syndrome
- Rosenthal Syndromes
- Syndrome, Rosenthal
- Deficiency, Factor XI
- Hemophilia C
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Below are MeSH descriptors whose meaning is more general than "Factor XI Deficiency".
Below are MeSH descriptors whose meaning is more specific than "Factor XI Deficiency".
This graph shows the total number of publications written about "Factor XI Deficiency" by people in this website by year, and whether "Factor XI Deficiency" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 1 | 0 | 1 | | 2003 | 1 | 0 | 1 | | 2004 | 1 | 0 | 1 | | 2006 | 1 | 0 | 1 | | 2007 | 1 | 0 | 1 | | 2015 | 1 | 0 | 1 |
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Below are the most recent publications written about "Factor XI Deficiency" by people in Profiles.
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Keskin EY, Gürsel T, Kaya Z, Dai L, Koçak Ü, Yenicesu I, Belen FB, Mitchell M. Molecular basis and bleeding manifestations of factor XI deficiency in 11 Turkish families. Blood Coagul Fibrinolysis. 2015 Jan; 26(1):63-8.
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Mitchell MJ, Dai L, Clarke JB, Bolton-Maggs PH, Savidge GF, Alhaq A. Characterisation of five factor XI mutations. Thromb Haemost. 2007 Jun; 97(6):884-9.
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Mitchell M, Mountford R, Butler R, Alhaq A, Dai L, Savidge G, Bolton-Maggs PH. Spectrum of factor XI (F11) mutations in the UK population--116 index cases and 140 mutations. Hum Mutat. 2006 Aug; 27(8):829.
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Dai L, Mitchell M, Carson P, Creagh D, Cutler J, Savidge G, Alhaq A. Severe factor XI deficiency caused by compound heterozygosity. Br J Haematol. 2004 Jun; 125(6):817-8.
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Mitchell M, Harrington P, Cutler J, Rangarajan S, Savidge G, Alhaq A. Eighteen unrelated patients with factor XI deficiency, four novel mutations and a 100% detection rate by denaturing high-performance liquid chromatography. Br J Haematol. 2003 May; 121(3):500-2.
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Connelly NR, Brull SJ. Anesthetic management of a patient with factor XI deficiency and factor XI inhibitor undergoing a cesarean section. Anesth Analg. 1993 Jun; 76(6):1365-6.
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