Wakefulness

"Wakefulness" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A state in which there is an enhanced potential for sensitivity and an efficient responsiveness to external stimuli.

Descriptor ID	D014851
MeSH Number(s)	F02.830.104.821 G11.561.035.738
Concept/Terms	Wakefulness Wakefulness Wakefulnesses

Below are MeSH descriptors whose meaning is more general than "Wakefulness".

Psychiatry and Psychology [F]
Psychological Phenomena [F02]
Psychophysiology [F02.830]
Arousal [F02.830.104]
Wakefulness [F02.830.104.821]
Biological Sciences [G]
Musculoskeletal and Neural Physiological Phenomena [G11]
Nervous System Physiological Phenomena [G11.561]
Arousal [G11.561.035]
Wakefulness [G11.561.035.738]

Below are MeSH descriptors whose meaning is related to "Wakefulness".

Below are MeSH descriptors whose meaning is more specific than "Wakefulness".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Wakefulness" by people in this website by year, and whether "Wakefulness" was a major or minor topic of these publications.

Bar chart showing 37 publications over 20 distinct years, with a maximum of 5 publications in 2015 and 2022

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	0	1	1
1998	0	1	1
2002	1	0	1
2003	0	1	1
2004	0	1	1
2005	0	2	2
2008	0	1	1
2010	1	2	3
2011	0	1	1
2012	0	1	1
2013	1	1	2
2014	0	1	1
2015	2	3	5
2018	0	1	1
2019	1	1	2
2020	1	1	2
2021	3	0	3
2022	0	5	5
2024	1	1	2
2025	0	1	1

Below are the most recent publications written about "Wakefulness" by people in Profiles.

Luo J, Pavlov I, Tavernier E, Perez Y, Kharat A, McNicholas B, Roca O, Vines DL, Ibarra-Estrada M, Alhazzani W, Lewis K, Simpson SQ, Rampon G, Liu L, Sun Q, Qiu H, Yang Y, Lapadula G, Qian ET, Gatto CL, Rice TW, Parhar KKS, Weatherald J, Walkey AJ, Bosch NA, Nay MA, Boulain T, Fossat G, Harris TRE, Thwaites CL, Phong NT, Bonfanti P, Yarahmadi S, Hashemian SM, Jayakumar D, Taylor SP, Johnson SA, Guerin C, Laffey JG, Ehrmann S, Li J. Awake Prone Positioning in Adults With COVID-19: An Individual Participant Data Meta-Analysis. JAMA Intern Med. 2025 May 01; 185(5):572-581.

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Petersen N, McCann KE, Stavarache MA, Kim LY, Weinshenker D, Winder DG. Adenosine A2A Receptors Link Astrocytic a1-Adrenergic Signaling to Wake-Promoting Dopamine Neurons. Biol Psychiatry. 2025 May 01; 97(9):915-928.

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Gamble MC, Miracle S, Williams BR, Logan RW. Endocannabinoid agonist 2-arachidonoylglycerol differentially alters diurnal activity and sleep during fentanyl withdrawal in male and female mice. Pharmacol Biochem Behav. 2024 07; 240:173791.

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Spencer RMC, Riggins T. Contributions of memory and brain development to the bioregulation of naps and nap transitions in early childhood. Proc Natl Acad Sci U S A. 2022 11; 119(44):e2123415119.

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Gamble MC, Chuan B, Gallego-Martin T, Shelton MA, Puig S, O'Donnell CP, Logan RW. A role for the circadian transcription factor NPAS2 in the progressive loss of non-rapid eye movement sleep and increased arousal during fentanyl withdrawal in male mice. Psychopharmacology (Berl). 2022 Oct; 239(10):3185-3200.

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Qian ET, Gatto CL, Amusina O, Dear ML, Hiser W, Buie R, Kripalani S, Harrell FE, Freundlich RE, Gao Y, Gong W, Hennessy C, Grooms J, Mattingly M, Bellam SK, Burke J, Zakaria A, Vasilevskis EE, Billings FT, Pulley JM, Bernard GR, Lindsell CJ, Rice TW. Assessment of Awake Prone Positioning in Hospitalized Adults With COVID-19: A Nonrandomized Controlled Trial. JAMA Intern Med. 2022 06 01; 182(6):612-621.

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Jones BJ, Chen ME, Simoncini L, Spencer RMC. Sleep enhances reconsolidation-based strengthening of visuospatial memories. Sci Rep. 2022 05 04; 12(1):7307.

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Li J, Luo J, Pavlov I, Perez Y, Tan W, Roca O, Tavernier E, Kharat A, McNicholas B, Ibarra-Estrada M, Vines DL, Bosch NA, Rampon G, Simpson SQ, Walkey AJ, Fralick M, Verma A, Razak F, Harris T, Laffey JG, Guerin C, Ehrmann S. Awake prone positioning for non-intubated patients with COVID-19-related acute hypoxaemic respiratory failure: a systematic review and meta-analysis. Lancet Respir Med. 2022 06; 10(6):573-583.

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Mason GM, Kurdziel LBF, Spencer RMC. The memory benefits of two naps per day during infancy: A pilot investigation. Infant Behav Dev. 2021 11; 65:101647.

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Garcia MA, Rampon GL, Doros G, Jia S, Jagan N, Gillmeyer K, Berical A, Hudspeth J, Ieong M, Modzelewski KL, Schechter-Perkins EM, Ross CS, Rucci JM, Simpson S, Walkey AJ, Bosch NA. Rationale and Design of the Awake Prone Position for Early Hypoxemia in COVID-19 Study Protocol: A Clinical Trial. Ann Am Thorac Soc. 2021 09; 18(9):1560-1566.

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