"Tyramine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An indirect sympathomimetic that occurs naturally in cheese and other foods. Tyramine does not directly activate adrenergic receptors, but it can serve as a substrate for adrenergic uptake systems and MONOAMINE OXIDASE to prolong the actions of adrenergic transmitters. It also provokes transmitter release from adrenergic terminals and may be a neurotransmitter in some invertebrate nervous systems.
| Descriptor ID |
D014439
|
| MeSH Number(s) |
D02.092.211.215.811
|
| Concept/Terms |
Tyramine- Tyramine
- 4-(2-Aminoethyl)phenol
- 4-Hydroxyphenethylamine
- 4 Hydroxyphenethylamine
|
Below are MeSH descriptors whose meaning is more general than "Tyramine".
Below are MeSH descriptors whose meaning is more specific than "Tyramine".
This graph shows the total number of publications written about "Tyramine" by people in this website by year, and whether "Tyramine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2013 | 2 | 0 | 2 |
| 2015 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Tyramine" by people in Profiles.
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Ma Z, Freeman MR. TrpML-mediated astrocyte microdomain Ca2+ transients regulate astrocyte-tracheal interactions. Elife. 2020 12 07; 9.
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De Rosa MJ, Veuthey T, Florman J, Grant J, Blanco MG, Andersen N, Donnelly J, Rayes D, Alkema MJ. The flight response impairs cytoprotective mechanisms by activating the insulin pathway. Nature. 2019 09; 573(7772):135-138.
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Ma Z, Stork T, Bergles DE, Freeman MR. Neuromodulators signal through astrocytes to alter neural circuit activity and behaviour. Nature. 2016 11 17; 539(7629):428-432.
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Pirri JK, Rayes D, Alkema MJ. A Change in the Ion Selectivity of Ligand-Gated Ion Channels Provides a Mechanism to Switch Behavior. PLoS Biol. 2015; 13(9):e1002238.
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Homberg U, Seyfarth J, Binkle U, Monastirioti M, Alkema MJ. Identification of distinct tyraminergic and octopaminergic neurons innervating the central complex of the desert locust, Schistocerca gregaria. J Comp Neurol. 2013 Jun 15; 521(9):2025-41.
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Donnelly JL, Clark CM, Leifer AM, Pirri JK, Haburcak M, Francis MM, Samuel AD, Alkema MJ. Monoaminergic orchestration of motor programs in a complex C. elegans behavior. PLoS Biol. 2013; 11(4):e1001529.
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Pirri JK, McPherson AD, Donnelly JL, Francis MM, Alkema MJ. A tyramine-gated chloride channel coordinates distinct motor programs of a Caenorhabditis elegans escape response. Neuron. 2009 May 28; 62(4):526-38.
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Alkema MJ, Hunter-Ensor M, Ringstad N, Horvitz HR. Tyramine Functions independently of octopamine in the Caenorhabditis elegans nervous system. Neuron. 2005 Apr 21; 46(2):247-60.