 Medulloblastoma
"Medulloblastoma" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A malignant neoplasm that may be classified either as a glioma or as a primitive neuroectodermal tumor of childhood (see NEUROECTODERMAL TUMOR, PRIMITIVE). The tumor occurs most frequently in the first decade of life with the most typical location being the cerebellar vermis. Histologic features include a high degree of cellularity, frequent mitotic figures, and a tendency for the cells to organize into sheets or form rosettes. Medulloblastoma have a high propensity to spread throughout the craniospinal intradural axis. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2060-1)
| Descriptor ID |
D008527
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| MeSH Number(s) |
C04.557.465.625.600.380.515 C04.557.465.625.600.590.500 C04.557.470.670.380.515 C04.557.470.670.590.500 C04.557.580.625.600.380.515 C04.557.580.625.600.590.500
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| Concept/Terms |
Melanocytic Medulloblastoma- Melanocytic Medulloblastoma
- Medulloblastoma, Melanocytic
- Medulloblastomas, Melanocytic
- Melanocytic Medulloblastomas
Medulloblastoma, Childhood- Medulloblastoma, Childhood
- Childhood Medulloblastoma
- Childhood Medulloblastomas
- Medulloblastomas, Childhood
Arachnoidal Cerebellar Sarcoma, Circumscribed- Arachnoidal Cerebellar Sarcoma, Circumscribed
- Sarcoma, Cerebellar, Circumscribed Arachnoidal
- Medulloblastoma, Desmoplastic
- Desmoplastic Medulloblastoma
- Desmoplastic Medulloblastomas
- Medulloblastomas, Desmoplastic
Medulloblastoma, Adult- Medulloblastoma, Adult
- Adult Medulloblastoma
- Adult Medulloblastomas
- Medulloblastomas, Adult
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Below are MeSH descriptors whose meaning is more general than "Medulloblastoma".
Below are MeSH descriptors whose meaning is more specific than "Medulloblastoma".
This graph shows the total number of publications written about "Medulloblastoma" by people in this website by year, and whether "Medulloblastoma" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1981 | 0 | 1 | 1 | | 1994 | 0 | 1 | 1 | | 2005 | 1 | 0 | 1 | | 2006 | 2 | 1 | 3 | | 2007 | 0 | 1 | 1 | | 2008 | 1 | 0 | 1 | | 2012 | 1 | 0 | 1 |
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Below are the most recent publications written about "Medulloblastoma" by people in Profiles.
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Clement J, Varlotto J, Rybka W, Frauenhoffer E, Drabick JJ. Unusual case of recurrent extraneural metastatic medulloblastoma in a young adult: durable complete remission with Ewing sarcoma chemotherapy regimen and consolidation with autologous bone marrow transplantation and local radiation. J Clin Oncol. 2013 Jul 1; 31(19):e316-9.
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Corno D, Daniela C, Pala M, Cominelli M, Cipelletti B, Leto K, Croci L, Barili V, Brandalise F, Melzi R, Di Gregorio A, Sergi LS, Politi LS, Piemonti L, Bulfone A, Rossi P, Rossi F, Consalez GG, Poliani PL, Galli R. Gene signatures associated with mouse postnatal hindbrain neural stem cells and medulloblastoma cancer stem cells identify novel molecular mediators and predict human medulloblastoma molecular classification. Cancer Discov. 2012 Jun; 2(6):554-68.
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Schüller U, Heine VM, Mao J, Kho AT, Dillon AK, Han YG, Huillard E, Sun T, Ligon AH, Qian Y, Ma Q, Alvarez-Buylla A, McMahon AP, Rowitch DH, Ligon KL. Acquisition of granule neuron precursor identity is a critical determinant of progenitor cell competence to form Shh-induced medulloblastoma. Cancer Cell. 2008 Aug 12; 14(2):123-34.
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Cochran DM, Yock TI, Adams JA, Tarbell NJ. Radiation dose to the lens during craniospinal irradiation-an improvement in proton radiotherapy technique. Int J Radiat Oncol Biol Phys. 2008 Apr 1; 70(5):1336-42.
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Mao J, Ligon KL, Rakhlin EY, Thayer SP, Bronson RT, Rowitch D, McMahon AP. A novel somatic mouse model to survey tumorigenic potential applied to the Hedgehog pathway. Cancer Res. 2006 Oct 15; 66(20):10171-8.
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Kim SK, Kim SU, Park IH, Bang JH, Aboody KS, Wang KC, Cho BK, Kim M, Menon LG, Black PM, Carroll RS. Human neural stem cells target experimental intracranial medulloblastoma and deliver a therapeutic gene leading to tumor regression. Clin Cancer Res. 2006 Sep 15; 12(18):5550-6.
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Miralbell R, Fitzgerald TJ, Laurie F, Kessel S, Glicksman A, Friedman HS, Urie M, Kepner JL, Zhou T, Chen Z, Barnes P, Kun L, Tarbell NJ. Radiotherapy in pediatric medulloblastoma: quality assessment of Pediatric Oncology Group Trial 9031. Int J Radiat Oncol Biol Phys. 2006 Apr 1; 64(5):1325-30.
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Ranke MB, Price DA, Lindberg A, Wilton P, Darendeliler F, Reiter EO. Final height in children with medulloblastoma treated with growth hormone. Horm Res. 2005; 64(1):28-34.
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Cahan MA, Walter KA, Colvin OM, Brem H. Cytotoxicity of taxol in vitro against human and rat malignant brain tumors. Cancer Chemother Pharmacol. 1994; 33(5):441-4.
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Abelson HT, Kufe DW, Skarin AT, Major P, Ensminger W, Beardsley GP, Canellos GP. Treatment of central nervous system tumors with methotrexate. Cancer Treat Rep. 1981; 65 Suppl 1:137-40.
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