Meningitis, Meningococcal
"Meningitis, Meningococcal" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A fulminant infection of the meninges and subarachnoid fluid by the bacterium NEISSERIA MENINGITIDIS, producing diffuse inflammation and peri-meningeal venous thromboses. Clinical manifestations include FEVER, nuchal rigidity, SEIZURES, severe HEADACHE, petechial rash, stupor, focal neurologic deficits, HYDROCEPHALUS, and COMA. The organism is usually transmitted via nasopharyngeal secretions and is a leading cause of meningitis in children and young adults. Organisms from Neisseria meningitidis serogroups A, B, C, Y, and W-135 have been reported to cause meningitis. (From Adams et al., Principles of Neurology, 6th ed, pp689-701; Curr Opin Pediatr 1998 Feb;10(1):13-8)
| Descriptor ID |
D008585
|
| MeSH Number(s) |
C01.252.200.500.550 C01.252.400.625.549.449 C10.228.228.180.500.750 C10.228.614.280.505
|
| Concept/Terms |
Meningitis, Meningococcal, Serogroup W-135- Meningitis, Meningococcal, Serogroup W-135
- Serogroup W135, Meningococcal Meningitis
- Meningitis, Meningococcal, Serogroup W135
- Meningococcal Meningitis, Serogroup W135
- Meningococcal Meningitis, Serogroup W-135
- Meningococcal Meningitis, Serogroup W 135
- Serogroup W-135, Meningococcal Meningitis
- Serogroup W 135, Meningococcal Meningitis
|
Below are MeSH descriptors whose meaning is more general than "Meningitis, Meningococcal".
Below are MeSH descriptors whose meaning is more specific than "Meningitis, Meningococcal".
This graph shows the total number of publications written about "Meningitis, Meningococcal" by people in this website by year, and whether "Meningitis, Meningococcal" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2015 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Meningitis, Meningococcal" by people in Profiles.
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Beernink PT, Vianzon V, Lewis LA, Moe GR, Granoff DM. A Meningococcal Outer Membrane Vesicle Vaccine with Overexpressed Mutant FHbp Elicits Higher Protective Antibody Responses in Infant Rhesus Macaques than a Licensed Serogroup B Vaccine. mBio. 2019 06 18; 10(3).
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Lujan E, Partridge E, Giuntini S, Ram S, Granoff DM. Breadth and Duration of Meningococcal Serum Bactericidal Activity in Health Care Workers and Microbiologists Immunized with the MenB-FHbp Vaccine. Clin Vaccine Immunol. 2017 Aug; 24(8).
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Giuntini S, Pajon R, Ram S, Granoff DM. Binding of complement factor H to PorB3 and NspA enhances resistance of Neisseria meningitidis to anti-factor H binding protein bactericidal activity. Infect Immun. 2015 Apr; 83(4):1536-45.
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Artenstein AW, Poland GA. Perspective: Elimination round. Nature. 2014 Mar 06; 507(7490):S16.
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Lewis LA, Vu DM, Vasudhev S, Shaughnessy J, Granoff DM, Ram S. Factor H-dependent alternative pathway inhibition mediated by porin B contributes to virulence of Neisseria meningitidis. mBio. 2013 Oct 15; 4(5):e00339-13.
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Artenstein AW, LaForce FM. Critical episodes in the understanding and control of epidemic meningococcal meningitis. Vaccine. 2012 Jun 29; 30(31):4701-7.
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Cooper ER, Ellison RT, Smith GS, Blaser MJ, Reller LB, Paisley JW. Rifampin-resistant meningococcal disease in a contact patient given prophylactic rifampin. J Pediatr. 1986 Jan; 108(1):93-6.
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Ellison RT, Kohler PF, Curd JG, Judson FN, Reller LB. Prevalence of congenital or acquired complement deficiency in patients with sporadic meningococcal disease. N Engl J Med. 1983 04 21; 308(16):913-6.