"Urease" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the conversion of urea and water to carbon dioxide and ammonia. EC 3.5.1.5.
| Descriptor ID |
D014510
|
| MeSH Number(s) |
D08.811.277.087.902
|
| Concept/Terms |
Urease- Urease
- Urea Amidohydrolase
- Amidohydrolase, Urea
|
Below are MeSH descriptors whose meaning is more general than "Urease".
Below are MeSH descriptors whose meaning is more specific than "Urease".
This graph shows the total number of publications written about "Urease" by people in this website by year, and whether "Urease" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2013 | 1 | 1 | 2 |
| 2015 | 0 | 1 | 1 |
| 2017 | 1 | 1 | 2 |
| 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Urease" by people in Profiles.
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Zambelli B, Basak P, Hu H, Piccioli M, Musiani F, Broll V, Imbert L, Boisbouvier J, Maroney MJ, Ciurli S. The structure of the high-affinity nickel-binding site in the Ni,Zn-HypA?UreE2 complex. Metallomics. 2023 03 06; 15(3).
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Blum FC, Hu HQ, Servetas SL, Benoit SL, Maier RJ, Maroney MJ, Merrell DS. Structure-function analyses of metal-binding sites of HypA reveal residues important for hydrogenase maturation in Helicobacter pylori. PLoS One. 2017; 12(8):e0183260.
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Hu HQ, Johnson RC, Merrell DS, Maroney MJ. Nickel Ligation of the N-Terminal Amine of HypA Is Required for Urease Maturation in Helicobacter pylori. Biochemistry. 2017 02 28; 56(8):1105-1116.
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Johnson RC, Hu HQ, Merrell DS, Maroney MJ. Dynamic HypA zinc site is essential for acid viability and proper urease maturation in Helicobacter pylori. Metallomics. 2015 Apr; 7(4):674-82.
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Maroney MJ, Ciurli S. Nonredox nickel enzymes. Chem Rev. 2014 Apr 23; 114(8):4206-28.
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Zambelli B, Berardi A, Martin-Diaconescu V, Mazzei L, Musiani F, Maroney MJ, Ciurli S. Nickel binding properties of Helicobacter pylori UreF, an accessory protein in the nickel-based activation of urease. J Biol Inorg Chem. 2014 Mar; 19(3):319-34.
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Martin-Diaconescu V, Bellucci M, Musiani F, Ciurli S, Maroney MJ. Unraveling the Helicobacter pylori UreG zinc binding site using X-ray absorption spectroscopy (XAS) and structural modeling. J Biol Inorg Chem. 2012 Mar; 17(3):353-61.
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Ge Z, Lee A, Whary MT, Rogers AB, Maurer KJ, Taylor NS, Schauer DB, Fox JG. Helicobacter hepaticus urease is not required for intestinal colonization but promotes hepatic inflammation in male A/JCr mice. Microb Pathog. 2008 Jul; 45(1):18-24.
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Tummala S, Sheth SG, Goldsmith JD, Goldar-Najafi A, Murphy CK, Osburne MS, Mullin S, Buxton D, Wagner DA, Kelly CP. Quantifying gastric Helicobacter pylori infection: a comparison of quantitative culture, urease breath testing, and histology. Dig Dis Sci. 2007 Feb; 52(2):396-401.
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Houghton J, Ramamoorthy R, Pandya H, Dhirmalani R, Kim KH. Human plasma is directly bacteriocidal against Helicobacter pylori in vitro, potentially explaining the decreased detection of Helicobacter pylori during acute upper GI bleeding. Gastrointest Endosc. 2002 Jan; 55(1):11-6.