Primary Myelofibrosis

"Primary Myelofibrosis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A de novo myeloproliferation arising from an abnormal stem cell. It is characterized by the replacement of bone marrow by fibrous tissue, a process that is mediated by CYTOKINES arising from the abnormal clone.

Descriptor ID	D055728
MeSH Number(s)	C15.378.190.636.765
Concept/Terms	Primary Myelofibrosis Primary Myelofibrosis Myelofibroses, Primary Myelofibrosis, Primary Primary Myelofibroses Bone Marrow Fibrosis Bone Marrow Fibroses Fibroses, Bone Marrow Fibrosis, Bone Marrow Myelofibrosis Myelofibroses Idiopathic Myelofibrosis Myeloid Metaplasia Metaplasia, Myeloid Metaplasias, Myeloid Myeloid Metaplasias Myelosclerosis Myeloscleroses Myelosis, Nonleukemic Myeloses, Nonleukemic Nonleukemic Myeloses Nonleukemic Myelosis Chronic Idiopathic Myelofibrosis Agnogenic Myeloid Metaplasia Agnogenic Myeloid Metaplasias Metaplasia, Agnogenic Myeloid Metaplasias, Agnogenic Myeloid Myeloid Metaplasia, Agnogenic Myeloid Metaplasias, Agnogenic Myelofibrosis With Myeloid Metaplasia

Below are MeSH descriptors whose meaning is more general than "Primary Myelofibrosis".

Diseases [C]
Hemic and Lymphatic Diseases [C15]
Hematologic Diseases [C15.378]
Bone Marrow Diseases [C15.378.190]
Myeloproliferative Disorders [C15.378.190.636]
Primary Myelofibrosis [C15.378.190.636.765]

Below are MeSH descriptors whose meaning is related to "Primary Myelofibrosis".

Below are MeSH descriptors whose meaning is more specific than "Primary Myelofibrosis".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Primary Myelofibrosis" by people in this website by year, and whether "Primary Myelofibrosis" was a major or minor topic of these publications.

Bar chart showing 8 publications over 6 distinct years, with a maximum of 2 publications in 2018 and 2020

To see the data from this visualization as text, click here.

Year	Major Topic	Total
2016	1	1
2017	1	1
2018	2	2
2020	2	2
2021	1	1
2022	1	1

Below are the most recent publications written about "Primary Myelofibrosis" by people in Profiles.

Nalluru SS, Efe O, Chen Y, Trivedi N. Acute myeloid leukemia and myelofibrosis: Simultaneous transformation of essential thrombocythemia during treatment with hydroxyurea. J Cancer Res Ther. 2022 Jul-Sep; 18(4):1180-1182.

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Saito N, Yamauchi T, Kawano N, Ono R, Yoshida S, Miyamoto T, Kamimura T, Shultz LD, Saito Y, Takenaka K, Shimoda K, Harada M, Akashi K, Ishikawa F. Circulating CD34+?cells of primary myelofibrosis patients contribute to myeloid-dominant hematopoiesis and bone marrow fibrosis in immunodeficient mice. Int J Hematol. 2022 Feb; 115(2):198-207.

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Gowin K, Ballen K, Ahn KW, Hu ZH, Ali H, Arcasoy MO, Devlin R, Coakley M, Gerds AT, Green M, Gupta V, Hobbs G, Jain T, Kandarpa M, Komrokji R, Kuykendall AT, Luber K, Masarova L, Michaelis LC, Patches S, Pariser AC, Rampal R, Stein B, Talpaz M, Verstovsek S, Wadleigh M, Agrawal V, Aljurf M, Angel Diaz M, Avalos BR, Bacher U, Bashey A, Beitinjaneh AM, Cerny J, Chhabra S, Copelan E, Cutler CS, DeFilipp Z, Gadalla SM, Ganguly S, Grunwald MR, Hashmi SK, Kharfan-Dabaja MA, Kindwall-Keller T, Kr?ger N, Lazarus HM, Liesveld JL, Litzow MR, Marks DI, Nathan S, Nishihori T, Olsson RF, Pawarode A, Rowe JM, Savani BN, Savoie ML, Seo S, Solh M, Tamari R, Verdonck LF, Yared JA, Alyea E, Popat U, Sobecks R, Scott BL, Nakamura R, Mesa R, Saber W. Survival following allogeneic transplant in patients with myelofibrosis. Blood Adv. 2020 05 12; 4(9):1965-1973.

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Verboon JM, Mahmut D, Kim AR, Nakamura M, Abdulhay NJ, Nandakumar SK, Gupta N, Akie TE, Geddis AE, Manes B, Kapp ME, Hofmann I, Gabriel SB, Klein DE, Williams DA, Frangoul HA, Parkhurst SM, Crane GM, Cantor AB, Sankaran VG. Infantile Myelofibrosis and Myeloproliferation with CDC42 Dysfunction. J Clin Immunol. 2020 05; 40(4):554-566.

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Shadur B, Asherie N, Newburger PE, Stepensky P. How we approach: Severe congenital neutropenia and myelofibrosis due to mutations in VPS45. Pediatr Blood Cancer. 2019 01; 66(1):e27473.

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Magoulas PL, Shchelochkov OA, Bainbridge MN, Ben-Shachar S, Yatsenko S, Potocki L, Lewis RA, Searby C, Marcogliese AN, Elghetany MT, Zapata G, Hern?ndez PP, Gadkari M, Einhaus D, Muzny DM, Gibbs RA, Bertuch AA, Scott DA, Corvera S, Franco LM. Syndromic congenital myelofibrosis associated with a loss-of-function variant in RBSN. Blood. 2018 08 09; 132(6):658-662.

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Shah RK, Munson M, Wierenga KJ, Pokala HR, Newburger PE, Crawford D. A novel homozygous VPS45 p.P468L mutation leading to severe congenital neutropenia with myelofibrosis. Pediatr Blood Cancer. 2017 Sep; 64(9).

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Mahadevan NR, Morgan EA, Mitchell RN. Case report and literature review: cardiac tamponade as a complication of pericardial extramedullary hematopoiesis. Cardiovasc Pathol. 2016 Sep-Oct; 25(5):371-4.

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Pati?o-Sarcinelli F, Knecht H, Pechet L, Pihan G, Savas L, Snyder LM. Leukemia with megakaryocytic differentiation following essential thrombocythemia and myelofibrosis. Case report and review of the literature. Acta Haematol. 1996; 95(2):122-8.

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Ginsberg MH, Frelinger AL, Lam SC, Forsyth J, McMillan R, Plow EF, Shattil SJ. Analysis of platelet aggregation disorders based on flow cytometric analysis of membrane glycoprotein IIb-IIIa with conformation-specific monoclonal antibodies. Blood. 1990 Nov 15; 76(10):2017-23.

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