 Ethylnitrosourea
"Ethylnitrosourea" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A nitrosourea compound with alkylating, carcinogenic, and mutagenic properties.
| Descriptor ID |
D005038
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| MeSH Number(s) |
D02.654.692.300 D02.948.594.310
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| Concept/Terms |
Ethylnitrosourea- Ethylnitrosourea
- Nitrosoethylurea
- N-Ethyl-N-nitrosourea
- N Ethyl N nitrosourea
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Below are MeSH descriptors whose meaning is more general than "Ethylnitrosourea".
Below are MeSH descriptors whose meaning is more specific than "Ethylnitrosourea".
This graph shows the total number of publications written about "Ethylnitrosourea" by people in this website by year, and whether "Ethylnitrosourea" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1991 | 1 | 0 | 1 | | 1992 | 1 | 0 | 1 | | 1993 | 1 | 0 | 1 | | 1999 | 1 | 1 | 2 | | 2004 | 0 | 1 | 1 | | 2005 | 1 | 0 | 1 | | 2006 | 0 | 1 | 1 | | 2008 | 0 | 1 | 1 | | 2009 | 0 | 1 | 1 |
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Below are the most recent publications written about "Ethylnitrosourea" by people in Profiles.
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Paudyal A, Damrau C, Patterson VL, Ermakov A, Formstone C, Lalanne Z, Wells S, Lu X, Norris DP, Dean CH, Henderson DJ, Murdoch JN. The novel mouse mutant, chuzhoi, has disruption of Ptk7 protein and exhibits defects in neural tube, heart and lung development and abnormal planar cell polarity in the ear. BMC Dev Biol. 2010 Aug 12; 10:87.
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Alexa K, Choe SK, Hirsch N, Etheridge L, Laver E, Sagerström CG. Maternal and zygotic aldh1a2 activity is required for pancreas development in zebrafish. PLoS One. 2009 Dec 11; 4(12):e8261.
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Croker BA, Lawson BR, Rutschmann S, Berger M, Eidenschenk C, Blasius AL, Moresco EM, Sovath S, Cengia L, Shultz LD, Theofilopoulos AN, Pettersson S, Beutler BA. Inflammation and autoimmunity caused by a SHP1 mutation depend on IL-1, MyD88, and a microbial trigger. Proc Natl Acad Sci U S A. 2008 Sep 30; 105(39):15028-33.
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Jang T, Savarese T, Low HP, Kim S, Vogel H, Lapointe D, Duong T, Litofsky NS, Weimann JM, Ross AH, Recht L. Osteopontin expression in intratumoral astrocytes marks tumor progression in gliomas induced by prenatal exposure to N-ethyl-N-nitrosourea. Am J Pathol. 2006 May; 168(5):1676-85.
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Savarese TM, Jang T, Low HP, Salmonsen R, Litofsky NS, Matuasevic Z, Ross AH, Recht LD. Isolation of immortalized, INK4a/ARF-deficient cells from the subventricular zone after in utero N-ethyl-N-nitrosourea exposure. J Neurosurg. 2005 Jan; 102(1):98-108.
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Jang T, Litofsky NS, Smith TW, Ross AH, Recht LD. Aberrant nestin expression during ethylnitrosourea-(ENU)-induced neurocarcinogenesis. Neurobiol Dis. 2004 Apr; 15(3):544-52.
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Castilla LH, Garrett L, Adya N, Orlic D, Dutra A, Anderson S, Owens J, Eckhaus M, Bodine D, Liu PP. The fusion gene Cbfb-MYH11 blocks myeloid differentiation and predisposes mice to acute myelomonocytic leukaemia. Nat Genet. 1999 Oct; 23(2):144-6.
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Ludlum DB, Li Q, Matijasevic Z. Role of base excision repair in protecting cells from the toxicity of chloroethylnitrosoureas. IARC Sci Publ. 1999; (150):271-7.
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Matijasevic Z, Boosalis M, Mackay W, Samson L, Ludlum DB. Protection against chloroethylnitrosourea cytotoxicity by eukaryotic 3-methyladenine DNA glycosylase. Proc Natl Acad Sci U S A. 1993 Dec 15; 90(24):11855-9.
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Ludlum DB, Habraken Y, Carter CA, Matijasevic Z. The formation and enzymatic repair of DNA modifications caused by the haloethylnitrosoureas and related compounds. Nucleic Acids Symp Ser. 1992; (27):25-6.
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