Succinate-Semialdehyde Dehydrogenase
"Succinate-Semialdehyde Dehydrogenase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that plays a role in the GLUTAMATE and butanoate metabolism pathways by catalyzing the oxidation of succinate semialdehyde to SUCCINATE using NAD+ as a coenzyme. Deficiency of this enzyme, causes 4-hydroxybutyricaciduria, a rare inborn error in the metabolism of the neurotransmitter 4-aminobutyric acid (GABA).
| Descriptor ID |
D050644
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| MeSH Number(s) |
D08.811.682.657.163.843
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| Concept/Terms |
Succinate-Semialdehyde Dehydrogenase- Succinate-Semialdehyde Dehydrogenase
- Dehydrogenase, Succinate-Semialdehyde
- Succinate Semialdehyde Dehydrogenase
- Dehydrogenase, Succinate Semialdehyde
- Semialdehyde Dehydrogenase, Succinate
- Succinic Semialdehyde Dehydrogenase
- Dehydrogenase, Succinic Semialdehyde
- Semialdehyde Dehydrogenase, Succinic
- NAD(+)-Dependent Succinic Semialdehyde Dehydrogenase
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Below are MeSH descriptors whose meaning is more general than "Succinate-Semialdehyde Dehydrogenase".
Below are MeSH descriptors whose meaning is more specific than "Succinate-Semialdehyde Dehydrogenase".
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Below are the most recent publications written about "Succinate-Semialdehyde Dehydrogenase" by people in Profiles.
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Pearl PL, Schreiber J, Theodore WH, McCarter R, Barrios ES, Yu J, Wiggs E, He J, Gibson KM. Taurine trial in succinic semialdehyde dehydrogenase deficiency and elevated CNS GABA. Neurology. 2014 Mar 18; 82(11):940-4.