"Mifepristone" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A progestational and glucocorticoid hormone antagonist. Its inhibition of progesterone induces bleeding during the luteal phase and in early pregnancy by releasing endogenous prostaglandins from the endometrium or decidua. As a glucocorticoid receptor antagonist, the drug has been used to treat hypercortisolism in patients with nonpituitary CUSHING SYNDROME.
| Descriptor ID |
D015735
|
| MeSH Number(s) |
D04.210.500.365.415.580
|
| Concept/Terms |
R-38486- R-38486
- R 38486
- RU-486
- RU 486
- RU486
- R38486
- RU-38486
- RU 38486
- RU38486
|
Below are MeSH descriptors whose meaning is more general than "Mifepristone".
Below are MeSH descriptors whose meaning is more specific than "Mifepristone".
This graph shows the total number of publications written about "Mifepristone" by people in this website by year, and whether "Mifepristone" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 2002 | 2 | 1 | 3 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 1 | 1 | 2 |
| 2006 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Mifepristone" by people in Profiles.
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Dom?nguez-Ord??ez R, Garcia-Ju?rez M, Lima-Hern?ndez FJ, G?mora-Arrati P, Dom?nguez-Salazar E, Blaustein JD, Etgen AM, Gonz?lez-Flores O. Lordosis facilitated by GPER-1 receptor activation involves GnRH-1, progestin and estrogen receptors in estrogen-primed rats. Horm Behav. 2018 02; 98:77-87.
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Dom?nguez-Ord??ez R, Garc?a-Ju?rez M, Lima-Hern?ndez FJ, G?mora-Arrati P, Blaustein JD, Gonz?lez-Flores O. Sexual receptivity facilitated by unesterified estradiol: Dependence on estrogen and progestin receptors and priming dose of estradiol benzoate. Behav Neurosci. 2015 Dec; 129(6):777-88.
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Alamdari N, Toraldo G, Aversa Z, Smith I, Castillero E, Renaud G, Qaisar R, Larsson L, Jasuja R, Hasselgren PO. Loss of muscle strength during sepsis is in part regulated by glucocorticoids and is associated with reduced muscle fiber stiffness. Am J Physiol Regul Integr Comp Physiol. 2012 Nov 15; 303(10):R1090-9.
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Sit D, Rothschild AJ, Creinin MD, Hanusa BH, Wisner KL. Psychiatric outcomes following medical and surgical abortion. Hum Reprod. 2007 Mar; 22(3):878-84.
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Rothschild AJ. Placebo response in psychotic depression. J Clin Psychiatry. 2005 Dec; 66(12):1615; author reply 1615-6.
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Shannon CS, Winikoff B, Hausknecht R, Schaff E, Blumenthal PD, Oyer D, Sankey H, Wolff J, Goldberg R. Multicenter trial of a simplified mifepristone medical abortion regimen. Obstet Gynecol. 2005 Feb; 105(2):345-51.
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Rothschild AJ. Conflict-of-interest charge. Am J Psychiatry. 2004 Sep; 161(9):1721-2; discussion 1722.
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Goldstein J, Sites CK, Toth MJ. Progesterone stimulates cardiac muscle protein synthesis via receptor-dependent pathway. Fertil Steril. 2004 Aug; 82(2):430-6.
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Blaustein JD. Progestin receptors: neuronal integrators of hormonal and environmental stimulation. Ann N Y Acad Sci. 2003 Dec; 1007:238-50.
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Belanoff JK, Rothschild AJ, Cassidy F, DeBattista C, Baulieu EE, Schold C, Schatzberg AF. An open label trial of C-1073 (mifepristone) for psychotic major depression. Biol Psychiatry. 2002 Sep 01; 52(5):386-92.