Adipocytes, Brown

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"Adipocytes, Brown" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Fat cells with dark coloration due to the densely packed MITOCHONDRIA. They contain numerous small lipid droplets or vacuoles. Their stored lipids can be converted directly to energy as heat by the mitochondria.

Descriptor ID	D052437
MeSH Number(s)	A11.329.114.249
Concept/Terms	Adipocytes, Brown Adipocytes, Brown Adipocyte, Brown Brown Adipocyte Brown Fat Cells Brown Fat Cell Cell, Brown Fat Cells, Brown Fat Fat Cell, Brown Fat Cells, Brown Brown Adipocytes

Below are MeSH descriptors whose meaning is more general than "Adipocytes, Brown".

Anatomy [A]
Cells [A11]
Connective Tissue Cells [A11.329]
Adipocytes [A11.329.114]
Adipocytes, Brown [A11.329.114.249]

Below are MeSH descriptors whose meaning is related to "Adipocytes, Brown".

Below are MeSH descriptors whose meaning is more specific than "Adipocytes, Brown".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Adipocytes, Brown" by people in this website by year, and whether "Adipocytes, Brown" was a major or minor topic of these publications.

Bar chart showing 16 publications over 10 distinct years, with a maximum of 3 publications in 2014 and 2020

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2008	1	0	1
2012	1	0	1
2014	3	0	3
2015	0	1	1
2016	0	1	1
2017	1	0	1
2018	2	0	2
2019	1	1	2
2020	3	0	3
2021	1	0	1

Below are the most recent publications written about "Adipocytes, Brown" by people in Profiles.

Tsagkaraki E, Nicoloro SM, DeSouza T, Solivan-Rivera J, Desai A, Lifshitz LM, Shen Y, Kelly M, Guilherme A, Henriques F, Amrani N, Ibraheim R, Rodriguez TC, Luk K, Maitland S, Friedline RH, Tauer L, Hu X, Kim JK, Wolfe SA, Sontheimer EJ, Corvera S, Czech MP. CRISPR-enhanced human adipocyte browning as cell therapy for metabolic disease. Nat Commun. 2021 11 26; 12(1):6931.

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Entwisle SW, Martinez Calejman C, Valente AS, Lawrence RT, Hung CM, Guertin DA, Villén J. Proteome and Phosphoproteome Analysis of Brown Adipocytes Reveals That RICTOR Loss Dampens Global Insulin/AKT Signaling. Mol Cell Proteomics. 2020 07; 19(7):1104-1119.

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Martinez Calejman C, Trefely S, Entwisle SW, Luciano A, Jung SM, Hsiao W, Torres A, Hung CM, Li H, Snyder NW, Villén J, Wellen KE, Guertin DA. mTORC2-AKT signaling to ATP-citrate lyase drives brown adipogenesis and de novo lipogenesis. Nat Commun. 2020 Jan 29; 11(1):575.

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Czech MP. Mechanisms of insulin resistance related to white, beige, and brown adipocytes. Mol Metab. 2020 04; 34:27-42.

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Jung SM, Hung CM, Hildebrand SR, Sanchez-Gurmaches J, Martinez-Pastor B, Gengatharan JM, Wallace M, Mukhopadhyay D, Martinez Calejman C, Luciano AK, Hsiao WY, Tang Y, Li H, Daniels DL, Mostoslavsky R, Metallo CM, Guertin DA. Non-canonical mTORC2 Signaling Regulates Brown Adipocyte Lipid Catabolism through SIRT6-FoxO1. Mol Cell. 2019 08 22; 75(4):807-822.e8.

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Sanchez-Gurmaches J, Martinez Calejman C, Jung SM, Li H, Guertin DA. Brown fat organogenesis and maintenance requires AKT1 and AKT2. Mol Metab. 2019 05; 23:60-74.

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Guilherme A, Pedersen DJ, Henriques F, Bedard AH, Henchey E, Kelly M, Morgan DA, Rahmouni K, Czech MP. Neuronal modulation of brown adipose activity through perturbation of white adipocyte lipogenesis. Mol Metab. 2018 10; 16:116-125.

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Chen Q, Huang L, Pan D, Zhu LJ, Wang YX. Cbx4 Sumoylates Prdm16 to Regulate Adipose Tissue Thermogenesis. Cell Rep. 2018 03 13; 22(11):2860-2872.

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Maurizi G, Poloni A, Mattiucci D, Santi S, Maurizi A, Izzi V, Giuliani A, Mancini S, Zingaretti MC, Perugini J, Severi I, Falconi M, Vivarelli M, Rippo MR, Corvera S, Giordano A, Leoni P, Cinti S. Human White Adipocytes Convert Into "Rainbow" Adipocytes In Vitro. J Cell Physiol. 2017 Oct; 232(10):2887-2899.

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Min SY, Kady J, Nam M, Rojas-Rodriguez R, Berkenwald A, Kim JH, Noh HL, Kim JK, Cooper MP, Fitzgibbons T, Brehm MA, Corvera S. Human 'brite/beige' adipocytes develop from capillary networks, and their implantation improves metabolic homeostasis in mice. Nat Med. 2016 Mar; 22(3):312-8.

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