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Alexey N Veraksa PhD

TitleAdjunct Professor
InstitutionUMass Chan Medical School
DepartmentMedicine
AddressUniversity of Massachusetts Boston
100 William T Morrissey Blvd
Boston MA 02125-3300
Phone617-287-6665
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    Other Positions
    InstitutionT.H. Chan School of Medicine
    DepartmentMedicine


    Collapse Biography 
    Collapse education and training
    University of California, San Diego, San Diego, CA, United StatesPHDDevelopmental Biology

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Paul S, Ilkhani K, Strozewski N, Yang L, Denberg DW, Christalin W, Locke V, Shvartsman SY, Veraksa A. ERK inhibits Capicua repressor function via multisite phosphorylation. J Cell Sci. 2026 Mar 15; 139(6). PMID: 41783984.
      Citations:    
    2. Webb J, Liew JJM, Gnann AD, Ilkhani K, Patterson M, Paul S, For?s M, Jim?nez G, Veraksa A, Dowling DP. Molecular basis of DNA recognition by the HMG-box-C1 module of capicua. Structure. 2025 Dec 04; 33(12):2109-2121.e5. PMID: 40967212.
      Citations:    
    3. Brown M, Sciascia E, Ning K, Adam W, Veraksa A. Regulation of Drosophila brain development and organ growth by the Minibrain/Rala signaling network. G3 (Bethesda). 2024 11 06; 14(11). PMID: 39271109.
      Citations:    
    4. Yang L, Zhu A, Aman JM, Denberg D, Kilwein MD, Marmion RA, Johnson ANT, Veraksa A, Singh M, W?hr M, Shvartsman SY. ERK synchronizes embryonic cleavages in Drosophila. Dev Cell. 2024 12 02; 59(23):3061-3071.e6. PMID: 39208802.
      Citations:    
    5. Brown M, Sciascia E, Ning K, Adam W, Veraksa A. Regulation of brain development by the Minibrain/Rala signaling network. bioRxiv. 2024 May 12. PMID: 38766038.
      Citations:    
    6. Portela M, Mukherjee S, Paul S, La Marca JE, Parsons LM, Veraksa A, Richardson HE. The Drosophila tumour suppressor Lgl and Vap33 activate the Hippo pathway through a dual mechanism. J Cell Sci. 2024 02 15; 137(4). PMID: 38240353.
      Citations:    
    7. Hudson J, Paul S, Veraksa A, Ghabrial A, Harvey KF, Poon C. NDR kinase tricornered genetically interacts with Ccm3 and metabolic enzymes in Drosophila melanogaster tracheal development. G3 (Bethesda). 2023 03 09; 13(3). PMID: 36653023.
      Citations:    
    8. Zhao H, Moberg KH, Veraksa A. Hippo pathway and Bonus control developmental cell fate decisions in the Drosophila eye. Dev Cell. 2023 03 13; 58(5):416-434.e12. PMID: 36868234.
      Citations:    
    9. Rodr?guez-Mu?oz L, Lagares C, Gonz?lez-Crespo S, Castel P, Veraksa A, Jim?nez G. Noncanonical function of Capicua as a growth termination signal in Drosophila oogenesis. Proc Natl Acad Sci U S A. 2022 08 02; 119(31):e2123467119. PMID: 35881788.
      Citations:    
    10. Barek H, Zhao H, Heath K, Veraksa A, Sugumaran M. Drosophila yellow-h encodes dopaminechrome tautomerase: A new enzyme in the eumelanin biosynthetic pathway. Pigment Cell Melanoma Res. 2022 01; 35(1):26-37. PMID: 34388859.
      Citations:    
    11. Paul S, Yang L, Mattingly H, Goyal Y, Shvartsman SY, Veraksa A. Activation-induced substrate engagement in ERK signaling. Mol Biol Cell. 2020 02 15; 31(4):235-243. PMID: 31913744.
      Citations:    
    12. Gundersen AE, Kugler BA, McDonald PM, Veraksa A, Houmard JA, Zou K. Altered mitochondrial network morphology and regulatory proteins in mitochondrial quality control in myotubes from severely obese humans with or without type 2 diabetes. Appl Physiol Nutr Metab. 2020 Mar; 45(3):283-293. PMID: 31356754.
      Citations:    
    13. Chai F, Xu W, Musoke T, Tarabelsi G, Assaad S, Freedman J, Peterson R, Piotrowska K, Byrnes J, Rogers S, Veraksa A. Structure-function analysis of ?-arrestin Kurtz reveals a critical role of receptor interactions in downregulation of GPCR signaling in vivo. Dev Biol. 2019 11 15; 455(2):409-419. PMID: 31325455.
      Citations:    
    14. Poon CLC, Liu W, Song Y, Gomez M, Kulaberoglu Y, Zhang X, Xu W, Veraksa A, Hergovich A, Ghabrial A, Harvey KF. A Hippo-like Signaling Pathway Controls Tracheal Morphogenesis in Drosophila melanogaster. Dev Cell. 2018 12 03; 47(5):564-575.e5. PMID: 30458981.
      Citations:    
    15. Portela M, Yang L, Paul S, Li X, Veraksa A, Parsons LM, Richardson HE. Lgl reduces endosomal vesicle acidification and Notch signaling by promoting the interaction between Vap33 and the V-ATPase complex. Sci Signal. 2018 06 05; 11(533). PMID: 29871910.
      Citations:    
    16. Barek H, Veraksa A, Sugumaran M. Drosophila melanogaster has the enzymatic machinery to make the melanic component of neuromelanin. Pigment Cell Melanoma Res. 2018 11; 31(6):683-692. PMID: 29741814.
      Citations:    
    17. Yang L, Paul S, DuBois-Coyne S, Kyriakakis P, Veraksa A. Medium-scale Preparation of Drosophila Embryo Extracts for Proteomic Experiments. J Vis Exp. 2017 05 30; (123). PMID: 28605365.
      Citations:    
    18. Yang L, Veraksa A. Single-Step Affinity Purification of ERK Signaling Complexes Using the Streptavidin-Binding Peptide (SBP) Tag. Methods Mol Biol. 2017; 1487:113-126. PMID: 27924562.
      Citations:    
    19. Yang L, Paul S, Trieu KG, Dent LG, Froldi F, For?s M, Webster K, Siegfried KR, Kondo S, Harvey K, Cheng L, Jim?nez G, Shvartsman SY, Veraksa A. Minibrain and Wings apart control organ growth and tissue patterning through down-regulation of Capicua. Proc Natl Acad Sci U S A. 2016 09 20; 113(38):10583-8. PMID: 27601662.
      Citations:    
    20. Nie Y, Li Q, Amcheslavsky A, Duhart JC, Veraksa A, Stocker H, Raftery LA, Ip YT. Bunched and Madm Function Downstream of Tuberous Sclerosis Complex to Regulate the Growth of Intestinal Stem Cells in Drosophila. Stem Cell Rev Rep. 2015 Dec; 11(6):813-25. PMID: 26323255.
      Citations: 1     Fields:    Translation:AnimalsCells
    21. Zhang C, Robinson BS, Xu W, Yang L, Yao B, Zhao H, Byun PK, Jin P, Veraksa A, Moberg KH. The ecdysone receptor coactivator Taiman links Yorkie to transcriptional control of germline stem cell factors in somatic tissue. Dev Cell. 2015 Jul 27; 34(2):168-80. PMID: 26143992.
      Citations:    
    22. Dent LG, Poon CL, Zhang X, Degoutin JL, Tipping M, Veraksa A, Harvey KF. The GTPase regulatory proteins Pix and Git control tissue growth via the Hippo pathway. Curr Biol. 2015 Jan 05; 25(1):124-30. PMID: 25484297.
      Citations:    
    23. Anjum SG, Xu W, Nikkholgh N, Basu S, Nie Y, Thomas M, Satyamurti M, Budnik BA, Ip YT, Veraksa A. Regulation of Toll signaling and inflammation by ?-arrestin and the SUMO protease Ulp1. Genetics. 2013 Dec; 195(4):1307-17. PMID: 24077307.
      Citations: 22     Fields:    Translation:AnimalsCells
    24. Degoutin JL, Milton CC, Yu E, Tipping M, Bosveld F, Yang L, Bellaiche Y, Veraksa A, Harvey KF. Riquiqui and minibrain are regulators of the hippo pathway downstream of Dachsous. Nat Cell Biol. 2013 Oct; 15(10):1176-85. PMID: 23955303.
      Citations:    
    25. Veraksa A. Regulation of developmental processes: insights from mass spectrometry-based proteomics. Wiley Interdiscip Rev Dev Biol. 2013 Sep-Oct; 2(5):723-34. PMID: 24014456.
      Citations:    
    26. Gilbert MM, Tipping M, Veraksa A, Moberg KH. A screen for conditional growth suppressor genes identifies the Drosophila homolog of HD-PTP as a regulator of the oncoprotein Yorkie. Dev Cell. 2011 May 17; 20(5):700-12. PMID: 21571226.
      Citations:    
    27. Tipping M, Kim Y, Kyriakakis P, Tong M, Shvartsman SY, Veraksa A. ?-arrestin Kurtz inhibits MAPK and Toll signalling in Drosophila development. EMBO J. 2010 Oct 06; 29(19):3222-35. PMID: 20802461.
      Citations:    
    28. Veraksa A. When peptides fly: advances in Drosophila proteomics. J Proteomics. 2010 Oct 10; 73(11):2158-70. PMID: 20580952.
      Citations:    
    29. Lake RJ, Grimm LM, Veraksa A, Banos A, Artavanis-Tsakonas S. In vivo analysis of the Notch receptor S1 cleavage. PLoS One. 2009 Aug 24; 4(8):e6728. PMID: 19701455.
      Citations:    
    30. Yelleswarapu CS, Tipping M, Kothapalli SR, Veraksa A, Rao DV. Common-path multimodal optical microscopy. Opt Lett. 2009 Apr 15; 34(8):1243-5. PMID: 19370131.
      Citations:    
    31. Kyriakakis P, Tipping M, Abed L, Veraksa A. Tandem affinity purification in Drosophila: the advantages of the GS-TAP system. Fly (Austin). 2008 Jul-Aug; 2(4):229-35. PMID: 18719405.
      Citations:    
    32. Omori Y, Zhao C, Saras A, Mukhopadhyay S, Kim W, Furukawa T, Sengupta P, Veraksa A, Malicki J. Elipsa is an early determinant of ciliogenesis that links the IFT particle to membrane-associated small GTPase Rab8. Nat Cell Biol. 2008 Apr; 10(4):437-44. PMID: 18364699.
      Citations:    
    33. Mukherjee A, Veraksa A, Bauer A, Rosse C, Camonis J, Artavanis-Tsakonas S. Regulation of Notch signalling by non-visual beta-arrestin. Nat Cell Biol. 2005 Dec; 7(12):1191-201. PMID: 16284625.
      Citations:    
    34. Veraksa A, Bauer A, Artavanis-Tsakonas S. Analyzing protein complexes in Drosophila with tandem affinity purification-mass spectrometry. Dev Dyn. 2005 Mar; 232(3):827-34. PMID: 15704125.
      Citations:    
    35. Moberg KH, Mukherjee A, Veraksa A, Artavanis-Tsakonas S, Hariharan IK. The Drosophila F box protein archipelago regulates dMyc protein levels in vivo. Curr Biol. 2004 Jun 08; 14(11):965-74. PMID: 15182669.
      Citations:    
    36. Veraksa A, Kennison J, McGinnis W. DEAF-1 function is essential for the early embryonic development of Drosophila. Genesis. 2002 Jun; 33(2):67-76. PMID: 12112874.
      Citations:    
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