 Macromolecular Substances
"Macromolecular Substances" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Compounds and molecular complexes that consist of very large numbers of atoms and are generally over 500 kDa in size. In biological systems macromolecular substances usually can be visualized using ELECTRON MICROSCOPY and are distinguished from ORGANELLES by the lack of a membrane structure.
| Descriptor ID |
D046911
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| MeSH Number(s) |
D05
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Macromolecular Substances".
Below are MeSH descriptors whose meaning is more specific than "Macromolecular Substances".
This graph shows the total number of publications written about "Macromolecular Substances" by people in this website by year, and whether "Macromolecular Substances" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1980 | 0 | 1 | 1 | | 1982 | 0 | 2 | 2 | | 1983 | 0 | 2 | 2 | | 1984 | 0 | 2 | 2 | | 1985 | 0 | 1 | 1 | | 1986 | 0 | 1 | 1 | | 1988 | 0 | 2 | 2 | | 1989 | 0 | 4 | 4 | | 1990 | 0 | 4 | 4 | | 1991 | 0 | 5 | 5 | | 1992 | 0 | 4 | 4 | | 1993 | 0 | 2 | 2 | | 1994 | 0 | 6 | 6 | | 1995 | 0 | 7 | 7 | | 1996 | 0 | 5 | 5 | | 1997 | 0 | 1 | 1 | | 1998 | 0 | 5 | 5 | | 1999 | 0 | 4 | 4 | | 2000 | 0 | 4 | 4 | | 2001 | 0 | 3 | 3 | | 2002 | 0 | 12 | 12 | | 2003 | 0 | 13 | 13 | | 2004 | 1 | 13 | 14 | | 2005 | 0 | 2 | 2 | | 2006 | 0 | 5 | 5 | | 2007 | 0 | 2 | 2 | | 2008 | 2 | 1 | 3 | | 2009 | 0 | 6 | 6 | | 2010 | 1 | 2 | 3 | | 2011 | 2 | 0 | 2 | | 2012 | 0 | 1 | 1 | | 2013 | 3 | 0 | 3 | | 2014 | 1 | 2 | 3 | | 2015 | 2 | 1 | 3 | | 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Macromolecular Substances" by people in Profiles.
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Scaletti F, Hardie J, Lee YW, Luther DC, Ray M, Rotello VM. Protein delivery into cells using inorganic nanoparticle-protein supramolecular assemblies. Chem Soc Rev. 2018 May 21; 47(10):3421-3432.
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Heider MR, Gu M, Duffy CM, Mirza AM, Marcotte LL, Walls AC, Farrall N, Hakhverdyan Z, Field MC, Rout MP, Frost A, Munson M. Subunit connectivity, assembly determinants and architecture of the yeast exocyst complex. Nat Struct Mol Biol. 2016 Jan; 23(1):59-66.
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Tullius R, Karimullah AS, Rodier M, Fitzpatrick B, Gadegaard N, Barron LD, Rotello VM, Cooke G, Lapthorn A, Kadodwala M. "Superchiral" Spectroscopy: Detection of Protein Higher Order Hierarchical Structure with Chiral Plasmonic Nanostructures. J Am Chem Soc. 2015 Jul 8; 137(26):8380-3.
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Bohn MF, Schiffer CA. REdiii: a pipeline for automated structure solution. Acta Crystallogr D Biol Crystallogr. 2015 May; 71(Pt 5):1059-67.
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Mout R, Tonga GY, Ray M, Moyano DF, Xing Y, Rotello VM. Environmentally responsive histidine-carboxylate zipper formation between proteins and nanoparticles. Nanoscale. 2014 Aug 7; 6(15):8873-7.
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Owa M, Furuta A, Usukura J, Arisaka F, King SM, Witman GB, Kamiya R, Wakabayashi K. Cooperative binding of the outer arm-docking complex underlies the regular arrangement of outer arm dynein in the axoneme. Proc Natl Acad Sci U S A. 2014 Jul 1; 111(26):9461-6.
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Sgolastra F, Minter LM, Osborne BA, Tew GN. Importance of sequence specific hydrophobicity in synthetic protein transduction domain mimics. Biomacromolecules. 2014 Mar 10; 15(3):812-20.
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Hatch SC, Sardo L, Chen J, Burdick R, Gorelick R, Fivash MJ, Pathak VK, Hu WS. Gag-dependent enrichment of HIV-1 RNA near the uropod membrane of polarized T cells. J Virol. 2013 Nov; 87(21):11912-5.
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Ren Z, Chan PW, Moffat K, Pai EF, Royer WE, Šrajer V, Yang X. Resolution of structural heterogeneity in dynamic crystallography. Acta Crystallogr D Biol Crystallogr. 2013 Jun; 69(Pt 6):946-59.
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Bogdanov AA, Mazzanti ML. Fluorescent macromolecular sensors of enzymatic activity for in vivo imaging. Prog Mol Biol Transl Sci. 2013; 113:349-87.
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