11-beta-Hydroxysteroid Dehydrogenase Type 2
"11-beta-Hydroxysteroid Dehydrogenase Type 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An high-affinity, NAD-dependent 11-beta-hydroxysteroid dehydrogenase that acts unidirectionally to catalyze the dehydrogenation of CORTISOL to CORTISONE. It is found predominantly in mineralocorticoid target tissues such as the KIDNEY; COLON; SWEAT GLANDS; and the PLACENTA. Absence of the enzyme leads to a fatal form of childhood hypertension termed, APPARENT MINERALOCORTICOID EXCESS SYNDROME.
| Descriptor ID |
D043209
|
| MeSH Number(s) |
D08.811.682.047.436.174.600 D08.811.682.047.820.100.600
|
| Concept/Terms |
11-beta-Hydroxysteroid Dehydrogenase Type 2- 11-beta-Hydroxysteroid Dehydrogenase Type 2
- 11 beta Hydroxysteroid Dehydrogenase Type 2
- 11beta-Hydroxysteroid Dehydrogenase Type 2
- 11beta Hydroxysteroid Dehydrogenase Type 2
- 11beta-HSD2
- 11beta-HSD2 Reductase
- 11 beta-HSD2
- 11 beta-Hydroxysteroid Dehydrogenase Type 2
|
Below are MeSH descriptors whose meaning is more general than "11-beta-Hydroxysteroid Dehydrogenase Type 2".
Below are MeSH descriptors whose meaning is more specific than "11-beta-Hydroxysteroid Dehydrogenase Type 2".
This graph shows the total number of publications written about "11-beta-Hydroxysteroid Dehydrogenase Type 2" by people in this website by year, and whether "11-beta-Hydroxysteroid Dehydrogenase Type 2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "11-beta-Hydroxysteroid Dehydrogenase Type 2" by people in Profiles.
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Adamidis A, Cantas-Orsdemir S, Tsirka A, Abbott MA, Visintainer P, Tonyushkina K. Apparent Mineralocorticoid Excess in the Pediatric Population: Report of a Novel Pathogenic Variant of the 11?-HSD2 Gene and Systematic Review of the Literature. Pediatr Endocrinol Rev. 2019 Mar; 16(3):335-358.