Poloxamer

"Poloxamer" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A nonionic polyoxyethylene-polyoxypropylene block co-polymer with the general formula HO(C2H4O)a(-C3H6O)b(C2H4O)aH. It is available in different grades which vary from liquids to solids. It is used as an emulsifying agent, solubilizing agent, surfactant, and wetting agent for antibiotics. Poloxamer is also used in ointment and suppository bases and as a tablet binder or coater. (Martindale The Extra Pharmacopoeia, 31st ed)

Descriptor ID	D020442
MeSH Number(s)	D02.033.455.250.700.682 D05.750.741.667 D25.720.741.667 J01.637.051.720.741.667
Concept/Terms	Poloxamer Poloxamer Poloxamer 188 Poloxamer 188 Poloxamer 338 Poloxamer 338 Poloxamer 407 Poloxamer 407 Poloxamers Poloxamers Pluronic F-108 Pluronic F-108 Pluronic F 108 Pluronic F108 Pluronic F-127 Pluronic F-127 Pluronic F 127 Pluronic F127 Pluronic F68 Pluronic F68 Pluronic F-68 Pluronic F 68 Pluronic L-101 Pluronic L-101 Pluronic L 101 Pluronic L101 Pluronic L-121 Pluronic L-121 Pluronic L 121 Pluronic L121 Pluronic L-81 Pluronic L-81 Pluronic L 81 Pluronic L81 Pluronics Pluronics Poloxalkol Poloxalkol Poloxamer 213 Poloxamer 213 Poloxamer 2930 Poloxamer 2930

Below are MeSH descriptors whose meaning is more general than "Poloxamer".

Chemicals and Drugs [D]
Organic Chemicals [D02]
Alcohols [D02.033]
Glycols [D02.033.455]
Ethylene Glycols [D02.033.455.250]
Polyethylene Glycols [D02.033.455.250.700]
Poloxamer [D02.033.455.250.700.682]
Macromolecular Substances [D05]
Polymers [D05.750]
Polyethylene Glycols [D05.750.741]
Poloxamer [D05.750.741.667]
Biomedical and Dental Materials [D25]
Polymers [D25.720]
Polyethylene Glycols [D25.720.741]
Poloxamer [D25.720.741.667]
Technology, Industry, Agriculture [J]
Technology, Industry, and Agriculture [J01]
Manufactured Materials [J01.637]
Biomedical and Dental Materials [J01.637.051]
Polymers [J01.637.051.720]
Polyethylene Glycols [J01.637.051.720.741]
Poloxamer [J01.637.051.720.741.667]

Below are MeSH descriptors whose meaning is related to "Poloxamer".

Below are MeSH descriptors whose meaning is more specific than "Poloxamer".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Poloxamer" by people in this website by year, and whether "Poloxamer" was a major or minor topic of these publications.

Bar chart showing 6 publications over 6 distinct years, with a maximum of 1 publications in 2005 and 2007 and 2017 and 2018 and 2021 and 2022

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2005	0	1	1
2007	0	1	1
2017	0	1	1
2018	1	0	1
2021	1	0	1
2022	1	0	1

Below are the most recent publications written about "Poloxamer" by people in Profiles.

Naeem S, Barkat K, Shabbir M, Khalid I, Anjum I, Shamshad N, Mehmood Y, Khan DH, Badshah SF, Syed MA, Afzal S, Abdullah Z. Fabrication of pH responsive hydrogel blends of chondroitin sulfate/pluronic F-127 for the controlled release of ketorolac: its characterization and acute oral toxicity study. Drug Dev Ind Pharm. 2022 Nov; 48(11):611-622.

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Casella JF, Barton BA, Kanter J, Black LV, Majumdar S, Inati A, Wali Y, Drachtman RA, Abboud MR, Kilinc Y, Fuh BR, Al-Khabori MK, Takemoto CM, Salman E, Sarnaik SA, Shah N, Morris CR, Keates-Baleeiro J, Raj A, Alvarez OA, Hsu LL, Thompson AA, Sisler IY, Pace BS, Noronha SA, Lasky JL, de Julian EC, Godder K, Thornburg CD, Kamberos NL, Nuss R, Marsh AM, Owen WC, Schaefer A, Tebbi CK, Chantrain CF, Cohen DE, Karakas Z, Piccone CM, George A, Fixler JM, Singleton TC, Moulton T, Quinn CT, de Castro Lobo CL, Almomen AM, Goyal-Khemka M, Maes P, Emanuele M, Gorney RT, Padgett CS, Parsley E, Kronsberg SS, Kato GJ, Gladwin MT. Effect of Poloxamer 188 vs Placebo on Painful Vaso-Occlusive Episodes in Children and Adults With Sickle Cell Disease: A Randomized Clinical Trial. JAMA. 2021 04 20; 325(15):1513-1523.

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Skinner M, Johnston BM, Liu Y, Hammer B, Selhorst R, Xenidou I, Perry SL, Emrick T. Synthesis of Zwitterionic Pluronic Analogs. Biomacromolecules. 2018 08 13; 19(8):3377-3389.

View in: PubMed
Huang L, Li Z, Zhao Y, Yang J, Yang Y, Pendharkar AI, Zhang Y, Kelmar S, Chen L, Wu W, Zhao J, Han G. Enhancing Photodynamic Therapy through Resonance Energy Transfer Constructed Near-Infrared Photosensitized Nanoparticles. Adv Mater. 2017 07; 29(28).

View in: PubMed
Monroy A, Kojima K, Ghanem MA, Paz AC, Kamil S, Vacanti CA, Eavey RD. Tissue engineered cartilage "bioshell" protective layer for subcutaneous implants. Int J Pediatr Otorhinolaryngol. 2007 Apr; 71(4):547-52.

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Quinlan JG, Wong BL, Niemeier RT, McCullough AS, Levin L, Emanuele M. Poloxamer 188 failed to prevent exercise-induced membrane breakdown in mdx skeletal muscle fibers. Neuromuscul Disord. 2006 Dec; 16(12):855-64.

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Kikuchi K, McDonald AD, Sasano T, Donahue JK. Targeted modification of atrial electrophysiology by homogeneous transmural atrial gene transfer. Circulation. 2005 Jan 25; 111(3):264-70.

View in: PubMed

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