"Off-Label Use" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The practice of prescribing or using a drug outside the scope of the drug's official approved label as designated by a regulatory agency concerning the treatment of a particular disease or condition.
| Descriptor ID |
D056687
|
| MeSH Number(s) |
E02.319.307.500
|
| Concept/Terms |
Off-Label Use- Off-Label Use
- Off Label Use
- Off-Label Uses
- Use, Off-Label
- Uses, Off-Label
- Off-Label Prescribing
- Off Label Prescribing
- Off-Label Prescribings
- Prescribing, Off-Label
- Prescribings, Off-Label
- Unlabeled Indication
- Indication, Unlabeled
- Indications, Unlabeled
- Unlabeled Indications
|
Below are MeSH descriptors whose meaning is more general than "Off-Label Use".
Below are MeSH descriptors whose meaning is more specific than "Off-Label Use".
This graph shows the total number of publications written about "Off-Label Use" by people in this website by year, and whether "Off-Label Use" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2013 | 0 | 1 | 1 |
| 2015 | 1 | 1 | 2 |
| 2017 | 1 | 0 | 1 |
| 2018 | 0 | 2 | 2 |
| 2021 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "Off-Label Use" by people in Profiles.
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Lindquist Lowen K, Smith S, Fuchs DC. Letter to the Editor: Acute Hypertriglyceridemia in an Infant Treated with Quetiapine for Pediatric Delirium. J Child Adolesc Psychopharmacol. 2021 09; 31(7):511-512.
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Lapane KL. Reducing Off-Label Antipsychotic Use in Older Adults: Time to Look Beyond the Doors of Nursing Homes. J Am Geriatr Soc. 2018 07; 66(6):1055-1057.
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Maxwell CJ, Campitelli MA, Hogan DB, Diong C, Austin PC, Amuah JE, Lapane K, Seitz DP, Gill SS, Gruneir A, Wodchis WP, Bronskill SE. Relevance of frailty to mortality associated with the use of antipsychotics among community-residing older adults with impaired cognition. Pharmacoepidemiol Drug Saf. 2018 03; 27(3):289-298.
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Semla TP, Lee A, Gurrera R, Bajor L, Li M, Miller DR, Smith EG, Wang C, Wan Y, Kazis LE, Bauer MS. Off-Label Prescribing of Second-Generation Antipsychotics to Elderly Veterans with Posttraumatic Stress Disorder and Dementia. J Am Geriatr Soc. 2017 Aug; 65(8):1789-1795.
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Tjia J, Reidenberg MM, Hunnicutt JN, Paice K, Donovan JL, Kanaan A, Briesacher BA, Lapane KL. Approaches to Gradual Dose Reduction of Chronic Off-Label Antipsychotics Used for Behavioral and Psychological Symptoms of Dementia. Consult Pharm. 2015 Oct; 30(10):599-611.
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Bonner AF, Field TS, Lemay CA, Mazor KM, Andersen DA, Compher CJ, Tjia J, Gurwitz JH. Rationales that providers and family members cited for the use of antipsychotic medications in nursing home residents with dementia. J Am Geriatr Soc. 2015 Feb; 63(2):302-8.
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Briesacher BA, Tjia J, Field T, Peterson D, Gurwitz JH. Antipsychotic use among nursing home residents. JAMA. 2013 Feb 06; 309(5):440-2.
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Anagnostis E, Wordell C, Guharoy R, Beckett R, Price V. A national survey on hospital formulary management processes. J Pharm Pract. 2011 Aug; 24(4):409-16.
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Memon MZ, Natarajan SK, Sharma J, Mathews MS, Snyder KV, Siddiqui AH, Hopkins LN, Levy EI. Safety and feasibility of intraarterial eptifibatide as a revascularization tool in acute ischemic stroke. J Neurosurg. 2011 Apr; 114(4):1008-13.