"beta-Lactamases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzymes found in many bacteria which catalyze the hydrolysis of the amide bond in the beta-lactam ring. Well known antibiotics destroyed by these enzymes are penicillins and cephalosporins.
| Descriptor ID |
D001618
|
| MeSH Number(s) |
D08.811.277.087.180
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "beta-Lactamases".
Below are MeSH descriptors whose meaning is more specific than "beta-Lactamases".
This graph shows the total number of publications written about "beta-Lactamases" by people in this website by year, and whether "beta-Lactamases" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
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Below are the most recent publications written about "beta-Lactamases" by people in Profiles.
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Li S, Su XH, Le WJ, Jiang FX, Wang BX, Rice PA. Antimicrobial susceptibility of Neisseria gonorrhoeae isolates from symptomatic men attending the Nanjing sexually transmitted diseases clinic (2011-2012): genetic characteristics of isolates with reduced sensitivity to ceftriaxone. BMC Infect Dis. 2014 Nov 27; 14:622.
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Dorit RL, Roy CM, Robinson SM, Riley MA. The evolutionary histories of clinical and environmental SHV ?-lactamases are intertwined. J Mol Evol. 2013 Jun; 76(6):388-93.
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Fong JJ, Rosé L, Radigan EA. Clinical outcomes with ertapenem as a first-line treatment option of infections caused by extended-spectrum ?-lactamase producing gram-negative bacteria. Ann Pharmacother. 2012 Mar; 46(3):347-52.
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Bamberger MH. Editorial comment. Urology. 2009 Jul; 74(1):123-4.
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Garvin LE, Bash MC, Keys C, Warner DM, Ram S, Shafer WM, Jerse AE. Phenotypic and genotypic analyses of Neisseria gonorrhoeae isolates that express frequently recovered PorB PIA variable region types suggest that certain P1a porin sequences confer a selective advantage for urogenital tract infection. Infect Immun. 2008 Aug; 76(8):3700-9.
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Li J, Cross JB, Vreven T, Meroueh SO, Mobashery S, Schlegel HB. Lysine carboxylation in proteins: OXA-10 beta-lactamase. Proteins. 2005 Nov 01; 61(2):246-57.
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Tipper DJ, Harley CA. Yeast genes controlling responses to topogenic signals in a model transmembrane protein. Mol Biol Cell. 2002 Apr; 13(4):1158-74.