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Charles Specht to Mice

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This is a "connection" page, showing publications Charles Specht has written about Mice.
Charles Specht
Connection Strength
0.783
Mice
  1. Specht CA, Wang R, Oliveira LVN, Hester MM, Gomez C, Mou Z, Carlson D, Lee CK, Hole CR, Lam WC, Upadhya R, Lodge JK, Levitz SM. Immunological correlates of protection mediated by a whole organism, Cryptococcus neoformans, vaccine deficient in chitosan. mBio. 2024 Aug 14; 15(8):e0174624.
    View in: PubMed
    Score: 0.089
  2. Hester MM, Carlson D, Lodge JK, Levitz SM, Specht CA. Immune evasion by Cryptococcus gattii in vaccinated mice coinfected with C. neoformans. Front Immunol. 2024; 15:1356651.
    View in: PubMed
    Score: 0.086
  3. Specht CA, Lam WC, Hester MM, Lourenco D, Levitz SM, Lodge JK, Upadhya R. Chitosan-Deficient Cryptococcus as Whole-Cell Vaccines. Methods Mol Biol. 2024; 2775:393-410.
    View in: PubMed
    Score: 0.085
  4. Specht CA, Homan EJ, Lee CK, Mou Z, Gomez CL, Hester MM, Abraham A, Rus F, Ostroff GR, Levitz SM. Protection of Mice against Experimental Cryptococcosis by Synthesized Peptides Delivered in Glucan Particles. mBio. 2021 02 22; 13(1):e0336721.
    View in: PubMed
    Score: 0.070
  5. Hester MM, Lee CK, Abraham A, Khoshkenar P, Ostroff GR, Levitz SM, Specht CA. Protection of mice against experimental cryptococcosis using glucan particle-based vaccines containing novel recombinant antigens. Vaccine. 2020 01 16; 38(3):620-626.
    View in: PubMed
    Score: 0.064
  6. Specht CA, Lee CK, Huang H, Hester MM, Liu J, Luckie BA, Torres Santana MA, Mirza Z, Khoshkenar P, Abraham A, Shen ZT, Lodge JK, Akalin A, Homan J, Ostroff GR, Levitz SM. Vaccination with Recombinant Cryptococcus Proteins in Glucan Particles Protects Mice against Cryptococcosis in a Manner Dependent upon Mouse Strain and Cryptococcal Species. mBio. 2017 11 28; 8(6).
    View in: PubMed
    Score: 0.056
  7. Specht CA, Nong S, Dan JM, Lee CK, Levitz SM. Contribution of glycosylation to T cell responses stimulated by recombinant Cryptococcus neoformans mannoprotein. J Infect Dis. 2007 Sep 01; 196(5):796-800.
    View in: PubMed
    Score: 0.027
  8. Levitz SM, Specht CA. The molecular basis for the immunogenicity of Cryptococcus neoformans mannoproteins. FEMS Yeast Res. 2006 Jun; 6(4):513-24.
    View in: PubMed
    Score: 0.025
  9. Wang R, Oliveira LVN, Hester MM, Carlson D, Christensen D, Specht CA, Levitz SM. Protection against experimental cryptococcosis elicited by Cationic Adjuvant Formulation 01-adjuvanted subunit vaccines. PLoS Pathog. 2024 Jul; 20(7):e1012220.
    View in: PubMed
    Score: 0.022
  10. Lee CK, Oliveira LVN, Akalin A, Specht CA, Lourenco D, Gomez CL, Ramirez-Ortiz ZG, Wang JP, Levitz SM. Dysregulated pulmonary inflammatory responses exacerbate the outcome of secondary aspergillosis following influenza. mBio. 2023 Oct 31; 14(5):e0163323.
    View in: PubMed
    Score: 0.021
  11. Soto ER, Specht CA, Rus F, Lee CK, Abraham A, Levitz SM, Ostroff GR. An efficient (nano) silica - In glucan particles protein encapsulation approach for improved thermal stability. J Control Release. 2023 05; 357:175-184.
    View in: PubMed
    Score: 0.020
  12. Hester MM, Oliveira LVN, Wang R, Mou Z, Lourenco D, Ostroff GR, Specht CA, Levitz SM. Cross-reactivity between vaccine antigens from the chitin deacetylase protein family improves survival in a mouse model of cryptococcosis. Front Immunol. 2022; 13:1015586.
    View in: PubMed
    Score: 0.020
  13. Yadav B, Specht CA, Lee CK, Pokrovskii M, Huh JR, Littman DR, Levitz SM. Lung eosinophils elicited during allergic and acute aspergillosis express ROR?t and IL-23R but do not require IL-23 for IL-17 production. PLoS Pathog. 2021 08; 17(8):e1009891.
    View in: PubMed
    Score: 0.018
  14. Lam WC, Upadhya R, Specht CA, Ragsdale AE, Hole CR, Levitz SM, Lodge JK. Chitosan Biosynthesis and Virulence in the Human Fungal Pathogen Cryptococcus gattii. mSphere. 2019 10 09; 4(5).
    View in: PubMed
    Score: 0.016
  15. Upadhya R, Baker LG, Lam WC, Specht CA, Donlin MJ, Lodge JK. Cryptococcus neoformans Cda1 and Its Chitin Deacetylase Activity Are Required for Fungal Pathogenesis. mBio. 2018 11 20; 9(6).
    View in: PubMed
    Score: 0.015
  16. Guerra ES, Lee CK, Specht CA, Yadav B, Huang H, Akalin A, Huh JR, Mueller C, Levitz SM. Central Role of IL-23 and IL-17 Producing Eosinophils as Immunomodulatory Effector Cells in Acute Pulmonary Aspergillosis and Allergic Asthma. PLoS Pathog. 2017 01; 13(1):e1006175.
    View in: PubMed
    Score: 0.013
  17. Upadhya R, Lam WC, Maybruck B, Specht CA, Levitz SM, Lodge JK. Induction of Protective Immunity to Cryptococcal Infection in Mice by a Heat-Killed, Chitosan-Deficient Strain of Cryptococcus neoformans. mBio. 2016 05 10; 7(3).
    View in: PubMed
    Score: 0.013
  18. Wiesner DL, Specht CA, Lee CK, Smith KD, Mukaremera L, Lee ST, Lee CG, Elias JA, Nielsen JN, Boulware DR, Bohjanen PR, Jenkins MK, Levitz SM, Nielsen K. Chitin recognition via chitotriosidase promotes pathologic type-2 helper T cell responses to cryptococcal infection. PLoS Pathog. 2015 Mar; 11(3):e1004701.
    View in: PubMed
    Score: 0.012
  19. Bueter CL, Lee CK, Wang JP, Ostroff GR, Specht CA, Levitz SM. Spectrum and mechanisms of inflammasome activation by chitosan. J Immunol. 2014 Jun 15; 192(12):5943-51.
    View in: PubMed
    Score: 0.011
  20. Huang H, Ostroff GR, Lee CK, Specht CA, Levitz SM. Characterization and optimization of the glucan particle-based vaccine platform. Clin Vaccine Immunol. 2013 Oct; 20(10):1585-91.
    View in: PubMed
    Score: 0.010
  21. Huang H, Ostroff GR, Lee CK, Agarwal S, Ram S, Rice PA, Specht CA, Levitz SM. Relative contributions of dectin-1 and complement to immune responses to particulate ?-glucans. J Immunol. 2012 Jul 01; 189(1):312-7.
    View in: PubMed
    Score: 0.010
  22. Bueter CL, Lee CK, Rathinam VAK, Healy GJ, Taron CH, Specht CA, Levitz SM. Chitosan but not chitin activates the inflammasome by a mechanism dependent upon phagocytosis. J Biol Chem. 2011 Oct 14; 286(41):35447-35455.
    View in: PubMed
    Score: 0.009
  23. Baker LG, Specht CA, Lodge JK. Cell wall chitosan is necessary for virulence in the opportunistic pathogen Cryptococcus neoformans. Eukaryot Cell. 2011 Sep; 10(9):1264-8.
    View in: PubMed
    Score: 0.009
  24. Ramirez-Ortiz ZG, Lee CK, Wang JP, Boon L, Specht CA, Levitz SM. A nonredundant role for plasmacytoid dendritic cells in host defense against the human fungal pathogen Aspergillus fumigatus. Cell Host Microbe. 2011 May 19; 9(5):415-24.
    View in: PubMed
    Score: 0.009
  25. Jesus MD, Nicola AM, Chow SK, Lee IR, Nong S, Specht CA, Levitz SM, Casadevall A. Glucuronoxylomannan, galactoxylomannan, and mannoprotein occupy spatially separate and discrete regions in the capsule of Cryptococcus neoformans. Virulence. 2010 Nov-Dec; 1(6):500-8.
    View in: PubMed
    Score: 0.009
  26. Huang H, Ostroff GR, Lee CK, Specht CA, Levitz SM. Robust stimulation of humoral and cellular immune responses following vaccination with antigen-loaded beta-glucan particles. mBio. 2010 Jul 20; 1(3).
    View in: PubMed
    Score: 0.008
  27. Gilbert NM, Donlin MJ, Gerik KJ, Specht CA, Djordjevic JT, Wilson CF, Sorrell TC, Lodge JK. KRE genes are required for beta-1,6-glucan synthesis, maintenance of capsule architecture and cell wall protein anchoring in Cryptococcus neoformans. Mol Microbiol. 2010 Apr; 76(2):517-34.
    View in: PubMed
    Score: 0.008
  28. Huang H, Ostroff GR, Lee CK, Wang JP, Specht CA, Levitz SM. Distinct patterns of dendritic cell cytokine release stimulated by fungal beta-glucans and toll-like receptor agonists. Infect Immun. 2009 May; 77(5):1774-81.
    View in: PubMed
    Score: 0.008
  29. Ramirez-Ortiz ZG, Specht CA, Wang JP, Lee CK, Bartholomeu DC, Gazzinelli RT, Levitz SM. Toll-like receptor 9-dependent immune activation by unmethylated CpG motifs in Aspergillus fumigatus DNA. Infect Immun. 2008 May; 76(5):2123-9.
    View in: PubMed
    Score: 0.007
  30. Lam JS, Mansour MK, Specht CA, Levitz SM. A model vaccine exploiting fungal mannosylation to increase antigen immunogenicity. J Immunol. 2005 Dec 01; 175(11):7496-503.
    View in: PubMed
    Score: 0.006
  31. Huang C, Nong SH, Mansour MK, Specht CA, Levitz SM. Purification and characterization of a second immunoreactive mannoprotein from Cryptococcus neoformans that stimulates T-Cell responses. Infect Immun. 2002 Oct; 70(10):5485-93.
    View in: PubMed
    Score: 0.005
  32. Hanlon DP, Specht C, Ferm VH. The chemical status of cadmium ion in the placenta. Environ Res. 1982 Feb; 27(1):89-94.
    View in: PubMed
    Score: 0.001
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