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Bruce J Simon MD

TitleAssociate Professor
InstitutionUMass Chan Medical School
AddressUMass Chan Medical School
55 Lake Avenue North
Worcester MA 01655
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    Other Positions
    InstitutionT.H. Chan School of Medicine
    DivisionTrauma/Critical Care

    Collapse Biography 
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    New York University, New York, NY, United StatesBAArts
    New York Medical College, Valhalla, NY, United StatesMD

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Morais A, Chung JY, Wu L, Ayata C, Simon B, Whalen MJ. Non-Invasive Vagal Nerve Stimulation Pre-Treatment Reduces Neurological Dysfunction After Closed Head Injury in Mice. Neurotrauma Rep. 2024; 5(1):150-158. PMID: 38435077.
    2. Czura CJ, Bikson M, Charvet L, Chen JDZ, Franke M, Fudim M, Grigsby E, Hamner S, Huston JM, Khodaparast N, Krames E, Simon BJ, Staats P, Vonck K. Neuromodulation Strategies to Reduce Inflammation and Improve Lung Complications in COVID-19 Patients. Front Neurol. 2022; 13:897124. PMID: 35911909.
    3. Liu TT, Morais A, Takizawa T, Mulder I, Simon BJ, Chen SP, Wang SJ, Ayata C, Yen JC. Efficacy profile of noninvasive vagus nerve stimulation on cortical spreading depression susceptibility and the tissue response in a rat model. J Headache Pain. 2022 Jan 21; 23(1):12. PMID: 35062860.
      Citations: 5     Fields:    Translation:Animals
    4. Williams CH, Scott EM, Dorfman JD, Simon BJ. Traumatic Injury Under COVID-19 Stay-at-Home Advisory: Experience of a New England Trauma Center. J Surg Res. 2022 01; 269:165-170. PMID: 34563843.
      Citations: 6     Fields:    Translation:HumansPHPublic Health
    5. Lindemann J, Rakers C, Matuskova H, Simon BJ, Kinfe T, Petzold GC. Vagus nerve stimulation reduces spreading depolarization burden and cortical infarct volume in a rat model of stroke. PLoS One. 2020; 15(7):e0236444. PMID: 32702055.
      Citations: 11     Fields:    Translation:HumansAnimals
    6. Morais A, Liu TT, Qin T, Sadhegian H, Ay I, Yagmur D, Mendes da Silva R, Chung D, Simon B, Guedes R, Chen SP, Wang SJ, Yen JC, Ayata C. Vagus nerve stimulation inhibits cortical spreading depression exclusively through central mechanisms. Pain. 2020 07; 161(7):1661-1669. PMID: 32142015.
      Citations: 17     Fields:    Translation:Animals
    7. Mondal B, Choudhury S, Simon B, Baker MR, Kumar H. Noninvasive vagus nerve stimulation improves gait and reduces freezing of gait in Parkinson's disease. Mov Disord. 2019 06; 34(6):917-918. PMID: 30869809.
      Citations: 18     Fields:    Translation:Humans
    8. Lerman I, Davis B, Huang M, Huang C, Sorkin L, Proudfoot J, Zhong E, Kimball D, Rao R, Simon B, Spadoni A, Strigo I, Baker DG, Simmons AN. Noninvasive vagus nerve stimulation alters neural response and physiological autonomic tone to noxious thermal challenge. PLoS One. 2019; 14(2):e0201212. PMID: 30759089.
      Citations: 25     Fields:    Translation:Humans
    9. Tarn J, Legg S, Mitchell S, Simon B, Ng WF. The Effects of Noninvasive Vagus Nerve Stimulation on Fatigue and Immune Responses in Patients With Primary Sj?gren's Syndrome. Neuromodulation. 2019 Jul; 22(5):580-585. PMID: 30328647.
      Citations: 41     Fields:    Translation:HumansCells
    10. Lewine JD, Paulson K, Bangera N, Simon BJ. Exploration of the Impact of Brief Noninvasive Vagal Nerve Stimulation on EEG and Event-Related Potentials. Neuromodulation. 2019 Jul; 22(5):564-572. PMID: 30288866.
      Citations: 21     Fields:    Translation:Humans
    11. Yang Y, Yang LY, Orban L, Cuylear D, Thompson J, Simon B, Yang Y. Non-invasive vagus nerve stimulation reduces blood-brain barrier disruption in a rat model of ischemic stroke. Brain Stimul. 2018 Jul - Aug; 11(4):689-698. PMID: 29496430.
      Citations: 39     Fields:    Translation:Animals
    12. Kaczmarczyk R, Tejera D, Simon BJ, Heneka MT. Microglia modulation through external vagus nerve stimulation in a murine model of Alzheimer's disease. J Neurochem. 2017 Dec 21. PMID: 29266221.
      Citations: 45     Fields:    
    13. Simon B, Blake J. Mechanism of action of non-invasive cervical vagus nerve stimulation for the treatment of primary headaches. Am J Manag Care. 2017 Nov; 23(17 Suppl):S312-S316. PMID: 29144716.
      Citations: 11     Fields:    Translation:HumansAnimals
    14. Mourdoukoutas AP, Truong DQ, Adair DK, Simon BJ, Bikson M. High-Resolution Multi-Scale Computational Model for Non-Invasive Cervical Vagus Nerve Stimulation. Neuromodulation. 2018 Apr; 21(3):261-268. PMID: 29076212.
      Citations: 39     Fields:    Translation:Humans
    15. Akerman S, Simon B, Romero-Reyes M. Vagus nerve stimulation suppresses acute noxious activation of trigeminocervical neurons in animal models of primary headache. Neurobiol Dis. 2017 Jun; 102:96-104. PMID: 28286178.
      Citations: 25     Fields:    Translation:AnimalsCells
    16. Chen SP, Ay I, Lopes de Morais A, Qin T, Zheng Y, Sadeghian H, Oka F, Simon B, Eikermann-Haerter K, Ayata C. Vagus nerve stimulation inhibits cortical spreading depression. Pain. 2016 Apr; 157(4):797-805. PMID: 26645547.
      Citations: 53     Fields:    Translation:Animals
    17. Lerman I, Hauger R, Sorkin L, Proudfoot J, Davis B, Huang A, Lam K, Simon B, Baker DG. Noninvasive Transcutaneous Vagus Nerve Stimulation Decreases Whole Blood Culture-Derived Cytokines and Chemokines: A Randomized, Blinded, Healthy Control Pilot Trial. Neuromodulation. 2016 Apr; 19(3):283-90. PMID: 26990318.
      Citations: 74     Fields:    Translation:HumansCells
    18. Kinfe TM, Pintea B, Muhammad S, Zaremba S, Roeske S, Simon BJ, Vatter H. Cervical non-invasive vagus nerve stimulation (nVNS) for preventive and acute treatment of episodic and chronic migraine and migraine-associated sleep disturbance: a prospective observational cohort study. J Headache Pain. 2015; 16:101. PMID: 26631234.
      Citations: 41     Fields:    Translation:Humans
    19. Ay I, Nasser R, Simon B, Ay H. Transcutaneous Cervical Vagus Nerve Stimulation Ameliorates Acute Ischemic Injury in Rats. Brain Stimul. 2016 Mar-Apr; 9(2):166-73. PMID: 26723020.
      Citations: 39     Fields:    Translation:Animals
    20. Oshinsky ML, Murphy AL, Hekierski H, Cooper M, Simon BJ. Noninvasive vagus nerve stimulation as treatment for trigeminal allodynia. Pain. 2014 May; 155(5):1037-1042. PMID: 24530613.
      Citations: 70     Fields:    Translation:Animals
    21. Simon B, Ebert J, Bokhari F, Capella J, Emhoff T, Hayward T, Rodriguez A, Smith L. Management of pulmonary contusion and flail chest: an Eastern Association for the Surgery of Trauma practice management guideline. J Trauma Acute Care Surg. 2012 Nov; 73(5 Suppl 4):S351-61. PMID: 23114493.
      Citations: 45     Fields:    Translation:Humans
    22. Hoffmann TJ, Simon BJ, Zhang Y, Emala CW. Low voltage vagal nerve stimulation reduces bronchoconstriction in guinea pigs through catecholamine release. Neuromodulation. 2012 Nov-Dec; 15(6):527-36. PMID: 22551486.
      Citations: 7     Fields:    Translation:Animals
    23. Barraco RD, Chiu WC, Clancy TV, Como JJ, Ebert JB, Hess LW, Hoff WS, Holevar MR, Quirk JG, Simon BJ, Weiss PM. Practice management guidelines for the diagnosis and management of injury in the pregnant patient: the EAST Practice Management Guidelines Work Group. J Trauma. 2010 Jul; 69(1):211-4. PMID: 20622592.
      Citations: 11     Fields:    Translation:Humans
    24. Hopper RA, VerHalen JP, Tepper O, Mehrara BJ, Detch R, Chang EI, Baharestani S, Simon BJ, Gurtner GC. Osteoblasts stimulated with pulsed electromagnetic fields increase HUVEC proliferation via a VEGF-A independent mechanism. Bioelectromagnetics. 2009 Apr; 30(3):189-97. PMID: 19194859.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    25. Schwartz Z, Fisher M, Lohmann CH, Simon BJ, Boyan BD. Osteoprotegerin (OPG) production by cells in the osteoblast lineage is regulated by pulsed electromagnetic fields in cultures grown on calcium phosphate substrates. Ann Biomed Eng. 2009 Mar; 37(3):437-44. PMID: 19139991.
      Citations: 14     Fields:    Translation:HumansCells
    26. Klopp LS, Simon BJ, Bush JM, Enns RM, Turner AS. Comparison of a caprolactone/lactide film (mesofol) to two polylactide film products as a barrier to postoperative peridural adhesion in an ovine dorsal laminectomy model. Spine (Phila Pa 1976). 2008 Jun 15; 33(14):1518-26. PMID: 18552667.
      Citations:    Fields:    Translation:Animals
    27. Callaghan MJ, Chang EI, Seiser N, Aarabi S, Ghali S, Kinnucan ER, Simon BJ, Gurtner GC. Pulsed electromagnetic fields accelerate normal and diabetic wound healing by increasing endogenous FGF-2 release. Plast Reconstr Surg. 2008 Jan; 121(1):130-141. PMID: 18176216.
      Citations: 39     Fields:    Translation:HumansAnimals
    28. Dodge GR, Bowen JR, Oh CW, Tokmakova K, Simon BJ, Aroojis A, Potter K. Electrical stimulation of the growth plate: a potential approach to an epiphysiodesis. Bioelectromagnetics. 2007 Sep; 28(6):463-70. PMID: 17492657.
      Citations: 4     Fields:    Translation:Animals
    29. Fredericks DC, Smucker J, Petersen EB, Bobst JA, Gan JC, Simon BJ, Glazer P. Effects of direct current electrical stimulation on gene expression of osteopromotive factors in a posterolateral spinal fusion model. Spine (Phila Pa 1976). 2007 Jan 15; 32(2):174-81. PMID: 17224811.
      Citations: 12     Fields:    Translation:Animals
    30. Aaron RK, Ciombor DM, Wang S, Simon B. Clinical biophysics: the promotion of skeletal repair by physical forces. Ann N Y Acad Sci. 2006 Apr; 1068:513-31. PMID: 16831948.
      Citations: 21     Fields:    Translation:HumansAnimals
    31. France JC, Norman TL, Buchanan MM, Scheel M, Veale M, Ackerman ES, Clovis NB, Kish VL, Simon B. Direct current stimulation for spine fusion in a nicotine exposure model. Spine J. 2006 Jan-Feb; 6(1):7-13. PMID: 16413441.
      Citations: 5     Fields:    Translation:Animals
    32. Simon BJ, Cushman J, Barraco R, Lane V, Luchette FA, Miglietta M, Roccaforte DJ, Spector R. Pain management guidelines for blunt thoracic trauma. J Trauma. 2005 Nov; 59(5):1256-67. PMID: 16385313.
      Citations: 28     Fields:    Translation:Humans
    33. Hannan EL, Farrell LS, Cooper A, Henry M, Simon B, Simon R. Physiologic trauma triage criteria in adult trauma patients: are they effective in saving lives by transporting patients to trauma centers? J Am Coll Surg. 2005 Apr; 200(4):584-92. PMID: 15804473.
      Citations: 14     Fields:    Translation:Humans
    34. Rosenspire AJ, Kindzelskii AL, Simon BJ, Petty HR. Real-time control of neutrophil metabolism by very weak ultra-low frequency pulsed magnetic fields. Biophys J. 2005 May; 88(5):3334-47. PMID: 15749780.
      Citations: 10     Fields:    Translation:HumansCells
    35. Tepper OM, Callaghan MJ, Chang EI, Galiano RD, Bhatt KA, Baharestani S, Gan J, Simon B, Hopper RA, Levine JP, Gurtner GC. Electromagnetic fields increase in vitro and in vivo angiogenesis through endothelial release of FGF-2. FASEB J. 2004 Aug; 18(11):1231-3. PMID: 15208265.
      Citations: 52     Fields:    Translation:HumansAnimalsCells
    36. Aaron RK, Ciombor DM, Simon BJ. Treatment of nonunions with electric and electromagnetic fields. Clin Orthop Relat Res. 2004 Feb; (419):21-9. PMID: 15021127.
      Citations: 51     Fields:    Translation:HumansAnimalsCells
    37. Aaron RK, Boyan BD, Ciombor DM, Schwartz Z, Simon BJ. Stimulation of growth factor synthesis by electric and electromagnetic fields. Clin Orthop Relat Res. 2004 Feb; (419):30-7. PMID: 15021128.
      Citations: 58     Fields:    Translation:HumansAnimalsCells
    38. Simon B, Gabor R, Letourneau P. Secondary triage of the injured pediatric patient within the trauma center: support for a selective resource-sparing two-stage system. Pediatr Emerg Care. 2004 Jan; 20(1):5-11. PMID: 14716158.
      Citations: 5     Fields:    Translation:HumansPHPublic Health
    39. Nelson FR, Brighton CT, Ryaby J, Simon BJ, Nielson JH, Lorich DG, Bolander M, Seelig J. Use of physical forces in bone healing. J Am Acad Orthop Surg. 2003 Sep-Oct; 11(5):344-54. PMID: 14565756.
      Citations: 25     Fields:    Translation:Humans
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