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Maria Gonzalez Perez PhD

TitleAssistant Professor
InstitutionUniversity of Massachusetts Medical School
DepartmentProgram in Molecular Medicine
AddressUniversity of Massachusetts Medical School
373 Plantation Street
Worcester MA 01605
Email
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    Other Positions
    InstitutionUMMS - School of Medicine
    DepartmentProgram in Molecular Medicine


    Collapse Biography 
    Collapse education and training
    Complutense University of Madrid, Madrid, , SpainBABiological Science
    Complutense University of Madrid, Madrid, , SpainBSBiochemistry
    Complutense University, Madrid, SpainB.S.2012Biochemistry
    Complutense University of Madrid, Madrid, , SpainPHD
    Complutense University, Madrid, Spain B.S.1994Biological Science

    Collapse Overview 

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Quitadamo B, Peters PJ, Repik A, O'Connell O, Mou Z, Koch M, Somasundaran M, Brody R, Luzuriaga K, Wallace A, Wang S, Lu S, McCauley S, Luban J, Duenas-Decamp M, Gonzalez-Perez MP, Clapham PR. HIV-1 R5 Macrophage-Tropic Envelope Glycoprotein Trimers Bind CD4 with High Affinity, while the CD4 Binding Site on Non-macrophage-tropic, T-Tropic R5 Envelopes Is Occluded. J Virol. 2018 Jan 15; 92(2). PMID: 29118121.
      View in: PubMed
    2. Gonzalez-Perez MP, Peters PJ, O'Connell O, Silva N, Harbison C, Cummings Macri S, Kaliyaperumal S, Luzuriaga K, Clapham PR. Identification of Emerging Macrophage-Tropic HIV-1 R5 Variants in Brain Tissue of AIDS Patients without Severe Neurological Complications. J Virol. 2017 Oct 15; 91(20). PMID: 28768859.
      View in: PubMed
    3. Peters PJ, Gonzalez-Perez MP, Musich T, Moore Simas TA, Lin R, Morse AN, Shattock RJ, Derdeyn CA, Clapham PR. Infection of ectocervical tissue and universal targeting of T-cells mediated by primary non-macrophage-tropic and highly macrophage-tropic HIV-1 R5 envelopes. Retrovirology. 2015 Jun 09; 12:48. PMID: 26055104.
      View in: PubMed
    4. Musich T, O'Connell O, Gonzalez-Perez MP, Derdeyn CA, Peters PJ, Clapham PR. HIV-1 non-macrophage-tropic R5 envelope glycoproteins are not more tropic for entry into primary CD4+ T-cells than envelopes highly adapted for macrophages. Retrovirology. 2015 Mar 14; 12:25. PMID: 25809903.
      View in: PubMed
    5. O'Connell O, Repik A, Reeves JD, Gonzalez-Perez MP, Quitadamo B, Anton ED, Duenas-Decamp M, Peters P, Lin R, Zolla-Pazner S, Corti D, Wallace A, Wang S, Kong XP, Lu S, Clapham PR. Efficiency of bridging-sheet recruitment explains HIV-1 R5 envelope glycoprotein sensitivity to soluble CD4 and macrophage tropism. J Virol. 2013 Jan; 87(1):187-98. PMID: 23055568.
      View in: PubMed
    6. Gonzalez-Perez MP, O'Connell O, Lin R, Sullivan WM, Bell J, Simmonds P, Clapham PR. Independent evolution of macrophage-tropism and increased charge between HIV-1 R5 envelopes present in brain and immune tissue. Retrovirology. 2012 Mar 15; 9:20. PMID: 22420378.
      View in: PubMed
    7. Brown RJ, Peters PJ, Caron C, Gonzalez-Perez MP, Stones L, Ankghuambom C, Pondei K, McClure CP, Alemnji G, Taylor S, Sharp PM, Clapham PR, Ball JK. Intercompartmental recombination of HIV-1 contributes to env intrahost diversity and modulates viral tropism and sensitivity to entry inhibitors. J Virol. 2011 Jun; 85(12):6024-37. PMID: 21471230.
      View in: PubMed
    8. Musich T, Peters PJ, Duenas-Decamp MJ, Gonzalez-Perez MP, Robinson J, Zolla-Pazner S, Ball JK, Luzuriaga K, Clapham PR. A conserved determinant in the V1 loop of HIV-1 modulates the V3 loop to prime low CD4 use and macrophage infection. J Virol. 2011 Mar; 85(5):2397-405. PMID: 21159865.
      View in: PubMed
    9. Duenas-Decamp MJ, Peters PJ, Repik A, Musich T, Gonzalez-Perez MP, Caron C, Brown R, Ball J, Clapham PR. Variation in the biological properties of HIV-1 R5 envelopes: implications of envelope structure, transmission and pathogenesis. Future Virol. 2010 Jul; 5(4):435-451. PMID: 20930940.
      View in: PubMed
    10. Ramil E, Sánchez AJ, González-Pérez P, Rodríguez-Antigüedad A, Gómez-Lozano N, Ortiz P, Arroyo R, De las Heras V, Vilches C, García-Merino A. The cannabinoid receptor 1 gene (CNR1) and multiple sclerosis: an association study in two case-control groups from Spain. Mult Scler. 2010 Feb; 16(2):139-46. PMID: 20007426.
      View in: PubMed
    11. Sánchez AJ, González-Pérez P, Galve-Roperh I, García-Merino A. R-(+)-[2,3-Dihydro-5-methyl-3-(4-morpholinylmethyl)-pyrrolo-[1,2,3-de]-1,4-benzoxazin-6-yl]-1-naphtalenylmethanone (WIN-2) ameliorates experimental autoimmune encephalomyelitis and induces encephalitogenic T cell apoptosis: partial involvement of the CB(2) receptor. Biochem Pharmacol. 2006 Dec 15; 72(12):1697-706. PMID: 17007821.
      View in: PubMed
    12. Sánchez AJ, Puerta C, Ballester S, González P, Arriaga A, García-Merino A. Rolipram impairs NF-kappaB activity and MMP-9 expression in experimental autoimmune encephalomyelitis. J Neuroimmunol. 2005 Nov; 168(1-2):13-20. PMID: 16182379.
      View in: PubMed
    13. González-Pérez MP, Muñoz-Juárez L, Cárdenas FC, Zarranz Imirizaldu JJ, Carranceja JC, García-Saiz A. Human T-cell leukemia virus type I infection in various recipients of transplants from the same donor. Transplantation. 2003 Apr 15; 75(7):1006-11. PMID: 12698089.
      View in: PubMed
    14. Ortiz M, Sanchez I, Gonzalez MP, León MI, Abeso N, Asumu E, García-Sáiz A. Molecular epidemiology of HIV type 1 subtypes in equatorial guinea. AIDS Res Hum Retroviruses. 2001 Jun 10; 17(9):851-5. PMID: 11429126.
      View in: PubMed
    15. Castilla J, Pachón I, González MP, Amela C, Muñoz L, Tello O, Noguer I, de Ory F, León P, Alonso M, Gil E, García-Sáiz A. Seroprevalence of HIV and HTLV in a representative sample of the Spanish population. Epidemiol Infect. 2000 Aug; 125(1):159-62. PMID: 11057971; PMCID: PMC2869581.
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