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Last Name

Maria Gonzalez Perez PhD

TitleAssistant Professor
InstitutionUniversity of Massachusetts Medical School
DepartmentProgram in Molecular Medicine
AddressUniversity of Massachusetts Medical School
373 Plantation Street
Worcester MA 01605
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    Other Positions
    InstitutionUMMS - School of Medicine
    DepartmentProgram in Molecular Medicine

    Collapse Biography 
    Collapse education and training
    Complutense University of Madrid, Madrid, , SpainBABiological Science
    Complutense University of Madrid, Madrid, , SpainBSBiochemistry
    Complutense University, Madrid, SpainB.S.2012Biochemistry
    Complutense University of Madrid, Madrid, , SpainPHDBiology
    Complutense University, Madrid, Spain B.S.1994Biological Science

    Collapse Overview 

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Quitadamo B, Peters PJ, Repik A, O'Connell O, Mou Z, Koch M, Somasundaran M, Brody R, Luzuriaga K, Wallace A, Wang S, Lu S, McCauley S, Luban J, Duenas-Decamp M, Gonzalez-Perez MP, Clapham PR. HIV-1 R5 Macrophage-Tropic Envelope Glycoprotein Trimers Bind CD4 with High Affinity, while the CD4 Binding Site on Non-macrophage-tropic, T-Tropic R5 Envelopes Is Occluded. J Virol. 2018 Jan 15; 92(2). PMID: 29118121.
      View in: PubMed
    2. Gonzalez-Perez MP, Peters PJ, O'Connell O, Silva N, Harbison C, Cummings Macri S, Kaliyaperumal S, Luzuriaga K, Clapham PR. Identification of Emerging Macrophage-Tropic HIV-1 R5 Variants in Brain Tissue of AIDS Patients without Severe Neurological Complications. J Virol. 2017 Oct 15; 91(20). PMID: 28768859.
      View in: PubMed
    3. Peters PJ, Gonzalez-Perez MP, Musich T, Moore Simas TA, Lin R, Morse AN, Shattock RJ, Derdeyn CA, Clapham PR. Infection of ectocervical tissue and universal targeting of T-cells mediated by primary non-macrophage-tropic and highly macrophage-tropic HIV-1 R5 envelopes. Retrovirology. 2015 Jun 09; 12:48. PMID: 26055104.
      View in: PubMed
    4. Musich T, O'Connell O, Gonzalez-Perez MP, Derdeyn CA, Peters PJ, Clapham PR. HIV-1 non-macrophage-tropic R5 envelope glycoproteins are not more tropic for entry into primary CD4+ T-cells than envelopes highly adapted for macrophages. Retrovirology. 2015 Mar 14; 12:25. PMID: 25809903.
      View in: PubMed
    5. O'Connell O, Repik A, Reeves JD, Gonzalez-Perez MP, Quitadamo B, Anton ED, Duenas-Decamp M, Peters P, Lin R, Zolla-Pazner S, Corti D, Wallace A, Wang S, Kong XP, Lu S, Clapham PR. Efficiency of bridging-sheet recruitment explains HIV-1 R5 envelope glycoprotein sensitivity to soluble CD4 and macrophage tropism. J Virol. 2013 Jan; 87(1):187-98. PMID: 23055568.
      View in: PubMed
    6. Gonzalez-Perez MP, O'Connell O, Lin R, Sullivan WM, Bell J, Simmonds P, Clapham PR. Independent evolution of macrophage-tropism and increased charge between HIV-1 R5 envelopes present in brain and immune tissue. Retrovirology. 2012 Mar 15; 9:20. PMID: 22420378.
      View in: PubMed
    7. Brown RJ, Peters PJ, Caron C, Gonzalez-Perez MP, Stones L, Ankghuambom C, Pondei K, McClure CP, Alemnji G, Taylor S, Sharp PM, Clapham PR, Ball JK. Intercompartmental recombination of HIV-1 contributes to env intrahost diversity and modulates viral tropism and sensitivity to entry inhibitors. J Virol. 2011 Jun; 85(12):6024-37. PMID: 21471230.
      View in: PubMed
    8. Musich T, Peters PJ, Duenas-Decamp MJ, Gonzalez-Perez MP, Robinson J, Zolla-Pazner S, Ball JK, Luzuriaga K, Clapham PR. A conserved determinant in the V1 loop of HIV-1 modulates the V3 loop to prime low CD4 use and macrophage infection. J Virol. 2011 Mar; 85(5):2397-405. PMID: 21159865.
      View in: PubMed
    9. Duenas-Decamp MJ, Peters PJ, Repik A, Musich T, Gonzalez-Perez MP, Caron C, Brown R, Ball J, Clapham PR. Variation in the biological properties of HIV-1 R5 envelopes: implications of envelope structure, transmission and pathogenesis. Future Virol. 2010 Jul; 5(4):435-451. PMID: 20930940.
      View in: PubMed
    10. Ramil E, Sánchez AJ, González-Pérez P, Rodríguez-Antigüedad A, Gómez-Lozano N, Ortiz P, Arroyo R, De las Heras V, Vilches C, García-Merino A. The cannabinoid receptor 1 gene (CNR1) and multiple sclerosis: an association study in two case-control groups from Spain. Mult Scler. 2010 Feb; 16(2):139-46. PMID: 20007426.
      View in: PubMed
    11. Sánchez AJ, González-Pérez P, Galve-Roperh I, García-Merino A. R-(+)-[2,3-Dihydro-5-methyl-3-(4-morpholinylmethyl)-pyrrolo-[1,2,3-de]-1,4-benzoxazin-6-yl]-1-naphtalenylmethanone (WIN-2) ameliorates experimental autoimmune encephalomyelitis and induces encephalitogenic T cell apoptosis: partial involvement of the CB(2) receptor. Biochem Pharmacol. 2006 Dec 15; 72(12):1697-706. PMID: 17007821.
      View in: PubMed
    12. Sánchez AJ, Puerta C, Ballester S, González P, Arriaga A, García-Merino A. Rolipram impairs NF-kappaB activity and MMP-9 expression in experimental autoimmune encephalomyelitis. J Neuroimmunol. 2005 Nov; 168(1-2):13-20. PMID: 16182379.
      View in: PubMed
    13. González-Pérez MP, Muñoz-Juárez L, Cárdenas FC, Zarranz Imirizaldu JJ, Carranceja JC, García-Saiz A. Human T-cell leukemia virus type I infection in various recipients of transplants from the same donor. Transplantation. 2003 Apr 15; 75(7):1006-11. PMID: 12698089.
      View in: PubMed
    14. Ortiz M, Sanchez I, Gonzalez MP, León MI, Abeso N, Asumu E, García-Sáiz A. Molecular epidemiology of HIV type 1 subtypes in equatorial guinea. AIDS Res Hum Retroviruses. 2001 Jun 10; 17(9):851-5. PMID: 11429126.
      View in: PubMed
    15. Castilla J, Pachón I, González MP, Amela C, Muñoz L, Tello O, Noguer I, de Ory F, León P, Alonso M, Gil E, García-Sáiz A. Seroprevalence of HIV and HTLV in a representative sample of the Spanish population. Epidemiol Infect. 2000 Aug; 125(1):159-62. PMID: 11057971; PMCID: PMC2869581.
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