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Maria Paz Gonzalez Perez PhD

TitleAssistant Professor
InstitutionUMass Chan Medical School
DepartmentBiochemistry and Molecular Biotechnology
AddressUniversity of Massachusetts Medical School
373 Plantation Street
Worcester MA 01605
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    Other Positions
    InstitutionT.H. Chan School of Medicine
    DepartmentBiochemistry and Molecular Biotechnology

    Collapse Biography 
    Collapse education and training
    Complutense University, Madrid, SpainB.S.2012Biochemistry
    Complutense University, Madrid, Spain B.S.1994Biological Science

    Collapse Overview 

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Rose R, Gonzalez-Perez MP, Nolan D, Ganta KK, LaFleur T, Cross S, Brody R, Lamers SL, Luzuriaga K. Distinct HIV-1 Population Structure across Meningeal and Peripheral T Cells and Macrophage Lineage Cells. Microbiol Spectr. 2022 Oct 26; 10(5):e0250822. PMID: 36173332.
    2. Rose R, Gonzalez-Perez MP, Nolan DJ, Cross S, Lamers SL, Luzuriaga K. Ultradeep HIV-1 Proviral Envelope Sequencing Reveals Complex Population Structure within and between Brain and Splenic Tissues. J Virol. 2021 11 09; 95(23):e0120221. PMID: 34495695.
    3. Lamers SL, Fogel GB, Nolan DJ, Barbier AE, Rose R, Singer EJ, Gonzalez-Perez MP, McGrath MS. Emerging Patterns in HIV-1 gp120 Variable Domains in Anatomical Tissues in the Absence of a Plasma Viral Load. AIDS Res Hum Retroviruses. 2019 06; 35(6):588-596. PMID: 30793919.
      Citations: 1     Fields:    Translation:HumansCells
    4. Quitadamo B, Peters PJ, Koch M, Luzuriaga K, Cheng-Mayer C, Clapham PR, Gonzalez-Perez MP. No detection of CD4-independent human immunodeficiency virus 1 envelope glycoproteins in brain tissue of patients with or without neurological complications. Arch Virol. 2019 Feb; 164(2):473-482. PMID: 30415390.
      Citations:    Fields:    Translation:HumansCells
    5. Brese RL, Gonzalez-Perez MP, Koch M, O'Connell O, Luzuriaga K, Somasundaran M, Clapham PR, Dollar JJ, Nolan DJ, Rose R, Lamers SL. Ultradeep single-molecule real-time sequencing of HIV envelope reveals complete compartmentalization of highly macrophage-tropic R5 proviral variants in brain and CXCR4-using variants in immune and peripheral tissues. J Neurovirol. 2018 08; 24(4):439-453. PMID: 29687407.
      Citations: 12     Fields:    Translation:HumansCells
    6. Quitadamo B, Peters PJ, Repik A, O'Connell O, Mou Z, Koch M, Somasundaran M, Brody R, Luzuriaga K, Wallace A, Wang S, Lu S, McCauley S, Luban J, Duenas-Decamp M, Gonzalez-Perez MP, Clapham PR. HIV-1 R5 Macrophage-Tropic Envelope Glycoprotein Trimers Bind CD4 with High Affinity, while the CD4 Binding Site on Non-macrophage-tropic, T-Tropic R5 Envelopes Is Occluded. J Virol. 2018 01 15; 92(2). PMID: 29118121.
      Citations: 9     Fields:    Translation:HumansCells
    7. Gonzalez-Perez MP, Peters PJ, O'Connell O, Silva N, Harbison C, Cummings Macri S, Kaliyaperumal S, Luzuriaga K, Clapham PR. Identification of Emerging Macrophage-Tropic HIV-1 R5 Variants in Brain Tissue of AIDS Patients without Severe Neurological Complications. J Virol. 2017 10 15; 91(20). PMID: 28768859.
      Citations: 11     Fields:    Translation:HumansCells
    8. Peters PJ, Gonzalez-Perez MP, Musich T, Moore Simas TA, Lin R, Morse AN, Shattock RJ, Derdeyn CA, Clapham PR. Infection of ectocervical tissue and universal targeting of T-cells mediated by primary non-macrophage-tropic and highly macrophage-tropic HIV-1 R5 envelopes. Retrovirology. 2015 Jun 09; 12:48. PMID: 26055104.
      Citations: 4     Fields:    Translation:HumansCells
    9. Musich T, O'Connell O, Gonzalez-Perez MP, Derdeyn CA, Peters PJ, Clapham PR. HIV-1 non-macrophage-tropic R5 envelope glycoproteins are not more tropic for entry into primary CD4+ T-cells than envelopes highly adapted for macrophages. Retrovirology. 2015 Mar 14; 12:25. PMID: 25809903.
      Citations: 10     Fields:    Translation:HumansCells
    10. O'Connell O, Repik A, Reeves JD, Gonzalez-Perez MP, Quitadamo B, Anton ED, Duenas-Decamp M, Peters P, Lin R, Zolla-Pazner S, Corti D, Wallace A, Wang S, Kong XP, Lu S, Clapham PR. Efficiency of bridging-sheet recruitment explains HIV-1 R5 envelope glycoprotein sensitivity to soluble CD4 and macrophage tropism. J Virol. 2013 Jan; 87(1):187-98. PMID: 23055568.
      Citations: 17     Fields:    Translation:HumansCells
    11. Gonzalez-Perez MP, O'Connell O, Lin R, Sullivan WM, Bell J, Simmonds P, Clapham PR. Independent evolution of macrophage-tropism and increased charge between HIV-1 R5 envelopes present in brain and immune tissue. Retrovirology. 2012 Mar 15; 9:20. PMID: 22420378.
      Citations: 28     Fields:    Translation:HumansCells
    12. Brown RJ, Peters PJ, Caron C, Gonzalez-Perez MP, Stones L, Ankghuambom C, Pondei K, McClure CP, Alemnji G, Taylor S, Sharp PM, Clapham PR, Ball JK. Intercompartmental recombination of HIV-1 contributes to env intrahost diversity and modulates viral tropism and sensitivity to entry inhibitors. J Virol. 2011 Jun; 85(12):6024-37. PMID: 21471230.
      Citations: 39     Fields:    Translation:HumansCells
    13. Musich T, Peters PJ, Duenas-Decamp MJ, Gonzalez-Perez MP, Robinson J, Zolla-Pazner S, Ball JK, Luzuriaga K, Clapham PR. A conserved determinant in the V1 loop of HIV-1 modulates the V3 loop to prime low CD4 use and macrophage infection. J Virol. 2011 Mar; 85(5):2397-405. PMID: 21159865.
      Citations: 45     Fields:    Translation:HumansCells
    14. Duenas-Decamp MJ, Peters PJ, Repik A, Musich T, Gonzalez-Perez MP, Caron C, Brown R, Ball J, Clapham PR. Variation in the biological properties of HIV-1 R5 envelopes: implications of envelope structure, transmission and pathogenesis. Future Virol. 2010 Jul; 5(4):435-451. PMID: 20930940.
    15. Ramil E, S?nchez AJ, Gonz?lez-P?rez P, Rodr?guez-Antig?edad A, G?mez-Lozano N, Ortiz P, Arroyo R, De las Heras V, Vilches C, Garc?a-Merino A. The cannabinoid receptor 1 gene (CNR1) and multiple sclerosis: an association study in two case-control groups from Spain. Mult Scler. 2010 Feb; 16(2):139-46. PMID: 20007426.
      Citations: 8     Fields:    Translation:HumansCells
    16. S?nchez AJ, Gonz?lez-P?rez P, Galve-Roperh I, Garc?a-Merino A. R-(+)-[2,3-Dihydro-5-methyl-3-(4-morpholinylmethyl)-pyrrolo-[1,2,3-de]-1,4-benzoxazin-6-yl]-1-naphtalenylmethanone (WIN-2) ameliorates experimental autoimmune encephalomyelitis and induces encephalitogenic T cell apoptosis: partial involvement of the CB(2) receptor. Biochem Pharmacol. 2006 Dec 15; 72(12):1697-706. PMID: 17007821.
      Citations: 23     Fields:    Translation:AnimalsCells
    17. S?nchez AJ, Puerta C, Ballester S, Gonz?lez P, Arriaga A, Garc?a-Merino A. Rolipram impairs NF-kappaB activity and MMP-9 expression in experimental autoimmune encephalomyelitis. J Neuroimmunol. 2005 Nov; 168(1-2):13-20. PMID: 16182379.
      Citations: 7     Fields:    Translation:AnimalsCells
    18. Gonz?lez-P?rez MP, Mu?oz-Ju?rez L, C?rdenas FC, Zarranz Imirizaldu JJ, Carranceja JC, Garc?a-Saiz A. Human T-cell leukemia virus type I infection in various recipients of transplants from the same donor. Transplantation. 2003 Apr 15; 75(7):1006-11. PMID: 12698089.
      Citations: 9     Fields:    Translation:HumansCellsPHPublic Health
    19. Ortiz M, Sanchez I, Gonzalez MP, Le?n MI, Abeso N, Asumu E, Garc?a-S?iz A. Molecular epidemiology of HIV type 1 subtypes in equatorial guinea. AIDS Res Hum Retroviruses. 2001 Jun 10; 17(9):851-5. PMID: 11429126.
      Citations: 8     Fields:    Translation:HumansCells
    20. Castilla J, Pach?n I, Gonz?lez MP, Amela C, Mu?oz L, Tello O, Noguer I, de Ory F, Le?n P, Alonso M, Gil E, Garc?a-S?iz A. Seroprevalence of HIV and HTLV in a representative sample of the Spanish population. Epidemiol Infect. 2000 Aug; 125(1):159-62. PMID: 11057971.
      Citations: 3     Fields:    Translation:HumansCells
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