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Susanne Muehlschlegel MD, MPH

TitleAssociate Professor
InstitutionUniversity of Massachusetts Medical School
DepartmentNeurology
Phone508-856-2527
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    Other Positions
    InstitutionUMMS - School of Medicine
    DepartmentAnesthesiology and Perioperative Medicine

    InstitutionUMMS - School of Medicine
    DepartmentNeurology

    InstitutionUMMS - School of Medicine
    DepartmentSurgery


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    Collapse Biography 
    Collapse education and training
    Hohe Landesschule Hanau, Hanau, , GermanyBAChemistry/ English
    Harvard University School of Public Health, Boston, MA, United StatesMPHPublic Health/ Clinical Effect
    Philipp University of Marburg, Marburg, , GermanyMDMedicine
    Collapse awards and honors
    1995 - 2002Studienstiftung des Deutschen Volkes (German National Merit) Scholarship , Studienstiftung des Deutschen Volkes
    2004Neuroscience Resident Teacher of the Year, University of Florida
    2005Neurology Resident Teacher of the Year, University of Florida
    2006Neurology Resident Teacher of the Year, University of Florida
    2006Alpha Omega Alpha (Staff Member), University of Florida College of Medicine
    2009Clinical Excellence Award “Organ Donation”, University of Massachusetts
    2010Clinical Excellence Award “Acute Stroke Team Member”, University of Massachusetts
    2011Clinical Excellence Award “Organ Donation”, University of Massachusetts
    2011 - 2012Faculty Scholar Award (awarded to women faculty at UMASS Medical School for outstanding research), University of Massachusetts Medical School
    2012 - 2014Councilor, CCEN Section, AAN
    2013Presidential Citation for Outstanding Contributions to Neurocritical Care, Neurocritical Care Society
    2013 - 2017Board of Directors, Neurocritical Care Society
    2014 - 2016Executive Committee Member, Critical Care and Emergency Neurology (CCEN) Section AAN
    2014 - 2015Executive Committee Member, Neurocritical Care Society
    2014Fellow of Neurocritical Care Society (FNCS), Neurocritical Care Society
    2016Fellow of Critical Care Medicine (FCCM), American College of Critical Care Medicine

    Collapse Overview 
    Collapse overview


    Research:

    Dr. Muehlschlegel completed clinical training in neurology, vascular neurology and neurocritical care, and is triple board certified in these subspecialties. She has obtained additional research training through the completion of the Harvard School of Public Health Summer Program for Clinical Effectiveness and Masters of Public Health Program, with a focus in Clinical Effectiveness. She has published in the area of cerebral vasoconstriction syndromes, in particular studying dantrolene as a novel means for prevention and treatment of cerebral vasospasm after subarachnoid hemorrhage, as well as in the reversible vasoconstriction syndrome “Call-Fleming-Syndrome”. Since attending as a neurointensivist at UMASS, she has been actively involved in improving the outcome prognostication of moderate-severe traumatic brain injury admitted to the neurointensive care unit. Mentored by senior epidemiologist Robert Goldberg, PhD, she is studying the longitudinal course of critically ill TBI patients, creating new prediction tools, and demonstrating the variability of outcome prognostication by clinicians. She is developing shared decision making tools, which may ultimately limit uninformed withdrawal of care or futile prolongation of life decisions by families and physician biases (http://informedmedicaldecisions.org/what-is-shared-decision-making). This work is in line with the Patient Protection and Affordable Care Act of 2010 which supports a national shared decision making program http://www.nejm.org/doi/full/10.1056/NEJMp1209500.



     



    Dr. Muehlschlegel is actively involved in the Neurocritical Care Society. Since 2013, she has been an elected member of the Board of Directors, and is currently serving a 4-year term. The Neurocritical Care Society is the largest international multidisciplinary neurocritical care professional society dedicated to improve the health care and outcomes of patients with life-threatening neurological illnesses by promoting quality patient care, professional collaboration, research, training and advocacy.



     



    Teaching:

    Dr. Muehlschlegel is a well-recognized teacher.  As a UMASS faculty member, Dr. Muehlschlegel is currently responsible for the supervision of surgical critical care fellows, residents, medical students and mid-level providers (PA/ARNP) in the trauma and neuro-ICU. She gives lectures regularly to neurology, emergency medicine, anesthesia and surgery residents. When on service in the ICU, she provides teaching to the ICU team with all its members during the daily SICU morning lectures. She teaches all ICU procedures as well as all clinical aspects of neurocritical care. She was creator and co-director of the UMASS Department of Neurology/Neuroscience Journal Club from 2008-2013. She has mentored many medical students and residents in her clinical research laboratory, as well as in the neuroICU.



     



    Clinical:

    As a neurointensivist, Dr. Muehlschlegel is one of only ~1,000 U.S. board certified subspecialists in this field. She is involved in the direct care of critically ill neurology, neurosurgery and trauma patients. She managed all neuroICU and general surgical ICU problems, including but not limited to ventilators, hemodynamics, sepsis, nutrition, electrolyte imbalances, acid-base disorders, infections, and ventriculostomies. She is known to communicate very effectively and empathetically with family members and establishes great rapport with patients and affected families.



     



    Post-Graduate Medical and Research Training:



    2002-2006 -- Neurology Residency, University of Florida



    2005-2006 -- Chief Resident (Neurology), University of Florida



    2006-2008 -- Neurocritical Care and Vascular Neurology Fellowship, Massachusetts General Hospital and Brigham & Women's Hospital, Harvard Medical School



    2007-2010 -- Masters of Public Health (Clinical Effectiveness), Harvard School of Public Health



     



    Collapse Rotation Projects


    Lab rotations are available for undergraduate and medical students, residents and fellows. Visiting students from abroad should inquire about visa requirements first before applying. Unfortunately, my lab cannot accept any basic scientists.




    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Wartenberg KE, Hwang DY, Häusler KG, Muehlschlegel S, Sakowitz OW, Madžar D, Hamer HM, Rabinstein AA, Greer DM, Hemphill JC, Meixensberger J, Varelas PN. Gap Analysis Regarding Prognostication in Neurocritical Care: A Joint Statement from the German Neurocritical Care Society and the Neurocritical Care Society. Neurocrit Care. 2019 Jul 31. PMID: 31368059.
      View in: PubMed
    2. Hutchinson PJ, Kolias AG, Tajsic T, Adeleye A, Aklilu AT, Apriawan T, Bajamal AH, Barthélemy EJ, Devi BI, Bhat D, Bulters D, Chesnut R, Citerio G, Cooper DJ, Czosnyka M, Edem I, El-Ghandour NMF, Figaji A, Fountas KN, Gallagher C, Hawryluk GWJ, Iaccarino C, Joseph M, Khan T, Laeke T, Levchenko O, Liu B, Liu W, Maas A, Manley GT, Manson P, Mazzeo AT, Menon DK, Michael DB, Muehlschlegel S, Okonkwo DO, Park KB, Rosenfeld JV, Rosseau G, Rubiano AM, Shabani HK, Stocchetti N, Timmons SD, Timofeev I, Uff C, Ullman JS, Valadka A, Waran V, Wells A, Wilson MH, Servadei F. Consensus statement from the International Consensus Meeting on the Role of Decompressive Craniectomy in the Management of Traumatic Brain Injury : Consensus statement. Acta Neurochir (Wien). 2019 May 28. PMID: 31134383.
      View in: PubMed
    3. Damani R, Mayer S, Dhar R, Martin RH, Nyquist P, Olson DM, Mejia-Mantilla JH, Muehlschlegel S, Jauch EC, Mocco J, Mutoh T, Suarez JI. Common Data Element for Unruptured Intracranial Aneurysm and Subarachnoid Hemorrhage: Recommendations from Assessments and Clinical Examination Workgroup/Subcommittee. Neurocrit Care. 2019 May 14. PMID: 31090013.
      View in: PubMed
    4. Mikati AG, Flahive J, Khan MW, Vedantam A, Gopinath S, Nordness MF, Robertson C, Patel MB, Sheth KN, Muehlschlegel S. Multicenter Validation of the Survival After Acute Civilian Penetrating Brain Injuries (SPIN) Score. Neurosurgery. 2019 May 07. PMID: 31065707.
      View in: PubMed
    5. Miller MM, Lowe J, Khan M, Azeem MU, Muehlschlegel S, Jun-O'Connell AH, Goddeau RP, Moonis M, Gritters D, Silver B, Henninger N. Clinical and Radiological Characteristics of Vitamin K Versus Non-Vitamin K Antagonist Oral Anticoagulation-Related Intracerebral Hemorrhage. Neurocrit Care. 2019 Jan 28. PMID: 30690686.
      View in: PubMed
    6. Ghasemi M, Azeem MU, Muehlschlegel S, Chu F, Henninger N. Prescription patterns for routine EEG ordering in patients with intracranial hemorrhage admitted to a neurointensive care unit. J Crit Care. 2019 Jan 11; 50:262-268. PMID: 30660914.
      View in: PubMed
    7. Muehlschlegel S. Subarachnoid Hemorrhage. Continuum (Minneap Minn). 2018 Dec; 24(6):1623-1657. PMID: 30516599.
      View in: PubMed
    8. Khan MW, Muehlschlegel S. Shared Decision Making in Neurocritical Care. Neurosurg Clin N Am. 2018 Apr; 29(2):315-321. PMID: 29502720.
      View in: PubMed
    9. Moskowitz J, Quinn T, Khan MW, Shutter L, Goldberg R, Col N, Mazor KM, Muehlschlegel S. Should We Use the IMPACT-Model for the Outcome Prognostication of TBI Patients? A Qualitative Study Assessing Physicians' Perceptions. MDM Policy Pract. 2018 Jan-Jun; 3(1):2381468318757987. PMID: 30288437.
      View in: PubMed
    10. Henninger N, Compton RA, Khan MW, Carandang R, Hall W, Muehlschlegel S. "Don't lose hope early": Hemorrhagic diffuse axonal injury on head computed tomography is not associated with poor outcome in moderate to severe traumatic brain injury patients. J Trauma Acute Care Surg. 2018 Mar; 84(3):473-482. PMID: 29140952.
      View in: PubMed
    11. Humble SS, Wilson LD, Wang L, Long DA, Smith MA, Siktberg JC, Mirhoseini MF, Bhatia A, Pruthi S, Day MA, Muehlschlegel S, Patel MB. Prognosis of Diffuse Axonal Injury with Traumatic Brain Injury. J Trauma Acute Care Surg. 2018 Feb 17. PMID: 29462087.
      View in: PubMed
    12. Khan MW, Muehlschlegel S. Shared Decision Making in Neurocritical Care. Neurol Clin. 2017 Nov; 35(4):825-834. PMID: 28962816.
      View in: PubMed
    13. Quinn T, Moskowitz J, Khan MW, Shutter L, Goldberg R, Col N, Mazor KM, Muehlschlegel S. What Families Need and Physicians Deliver: Contrasting Communication Preferences Between Surrogate Decision-Makers and Physicians During Outcome Prognostication in Critically Ill TBI Patients. Neurocrit Care. 2017 Oct; 27(2):154-162. PMID: 28685395.
      View in: PubMed
    14. Osgood M, Muehlschlegel S. POINT: Should Continuous Venovenous Hemofiltration Always Be the Preferred Mode of Renal Replacement Therapy for the Patient With Acute Brain Injury? Yes. Chest. 2017 12; 152(6):1109-1111. PMID: 28911910.
      View in: PubMed
    15. Osgood M, Muehlschlegel S. Rebuttal From Drs Osgood and Muehlschlegel. Chest. 2017 12; 152(6):1114-1115. PMID: 28911912.
      View in: PubMed
    16. Marehbian J, Muehlschlegel S, Edlow BL, Hinson HE, Hwang DY. Medical Management of the Severe Traumatic Brain Injury Patient. Neurocrit Care. 2017 Jun 01. PMID: 28573388.
      View in: PubMed
    17. Cheng K, Bassil R, Carandang R, Hall W, Muehlschlegel S. The Estimated Verbal GCS Subscore in Intubated Traumatic Brain Injury Patients-Is it Really Better? J Neurotrauma. 2016 Dec 02. PMID: 27774844.
      View in: PubMed
    18. Muehlschlegel S, Ayturk D, Ahlawat A, Izzy S, Scalea TM, Stein DM, Emhoff T, Sheth KN. Predicting survival after acute civilian penetrating brain injuries: The SPIN score. Neurology. 2016 Nov 22; 87(21):2244-2253. PMID: 27784772.
      View in: PubMed
    19. Ahlawat A, Carandang R, Heard SO, Muehlschlegel S. The Modified Apnea Test During Brain Death Determination: An Alternative in Patients With Hypoxia. J Intensive Care Med. 2016 Jan; 31(1):66-9. PMID: 26574562.
      View in: PubMed
    20. Cai X, Robinson J, Muehlschlegel S, White DB, Holloway RG, Sheth KN, Fraenkel L, Hwang DY. Patient Preferences and Surrogate Decision Making in Neuroscience Intensive Care Units. Neurocrit Care. 2015 Aug; 23(1):131-41. PMID: 25990137.
      View in: PubMed
    21. Muehlschlegel S, Shutter L, Col N, Goldberg R. Decision Aids and Shared Decision-Making in Neurocritical Care: An Unmet Need in Our NeuroICUs. Neurocrit Care. 2015 Aug; 23(1):127-30. PMID: 25561435.
      View in: PubMed
    22. Osgood M, Compton R, Carandang R, Hall W, Kershaw G, Muehlschlegel S. Rapid unexpected brain herniation in association with renal replacement therapy in acute brain injury: caution in the neurocritical care unit. Neurocrit Care. 2015 Apr; 22(2):176-83. PMID: 25228117.
      View in: PubMed
    23. Henninger N, Izzy S, Carandang R, Hall W, Muehlschlegel S. Severe leukoaraiosis portends a poor outcome after traumatic brain injury. Neurocrit Care. 2014 Dec; 21(3):483-95. PMID: 24752459.
      View in: PubMed
    24. Muehlschlegel S, Carandang R, Hall W, Kini N, Izzy S, Garland B, Ouillette C, van der Bom IM, Flood TF, Gounis MJ, Weaver JP, Barton B, Wakhloo AK. Dantrolene for cerebral vasospasm after subarachnoid haemorrhage: a randomised double blind placebo-controlled safety trial. J Neurol Neurosurg Psychiatry. 2015 Sep; 86(9):1029-35. PMID: 25344064.
      View in: PubMed
    25. Izzy S, Muehlschlegel S. Cerebral vasospasm after aneurysmal subarachnoid hemorrhage and traumatic brain injury. Curr Treat Options Neurol. 2014 Jan; 16(1):278. PMID: 24347030.
      View in: PubMed
    26. Izzy S, Compton R, Carandang R, Hall W, Muehlschlegel S. Self-fulfilling prophecies through withdrawal of care: do they exist in traumatic brain injury, too? Neurocrit Care. 2013 Dec; 19(3):347-63. PMID: 24132565.
      View in: PubMed
    27. Muehlschlegel S, Kursun O, Topcuoglu MA, Fok J, Singhal AB. Differentiating reversible cerebral vasoconstriction syndrome with subarachnoid hemorrhage from other causes of subarachnoid hemorrhage. JAMA Neurol. 2013 Oct; 70(10):1254-60. PMID: 23939614.
      View in: PubMed
    28. Muehlschlegel S, Carandang R, Ouillette C, Hall W, Anderson F, Goldberg R. Frequency and impact of intensive care unit complications on moderate-severe traumatic brain injury: early results of the Outcome Prognostication in Traumatic Brain Injury (OPTIMISM) Study. Neurocrit Care. 2013 Jun; 18(3):318-31. PMID: 23377884.
      View in: PubMed
    29. Tisdell J, Smith TW, Muehlschlegel S. Multiple septic brain emboli in infectious endocarditis. Arch Neurol. 2012 Sep; 69(9):1206-7. PMID: 22964915.
      View in: PubMed
    30. Rivera-Lara L, Zhang J, Muehlschlegel S. Therapeutic hypothermia for acute neurological injuries. Neurotherapeutics. 2012 Jan; 9(1):73-86. PMID: 22173727.
      View in: PubMed
    31. Muehlschlegel S, Rordorf G, Sims J. Effects of a single dose of dantrolene in patients with cerebral vasospasm after subarachnoid hemorrhage: a prospective pilot study. Stroke. 2011 May; 42(5):1301-6. PMID: 21454813.
      View in: PubMed
    32. Muehlschlegel S, Selb J, Patel M, Diamond SG, Franceschini MA, Sorensen AG, Boas DA, Schwamm LH. Feasibility of NIRS in the neurointensive care unit: a pilot study in stroke using physiological oscillations. Neurocrit Care. 2009; 11(2):288-95. PMID: 19649749.
      View in: PubMed
    33. Muehlschlegel S, Voetsch B, Sorond FA. Emergent epidural blood patch: lifesaving treatment of paradoxical herniation. Arch Neurol. 2009 May; 66(5):670-1. PMID: 19433672.
      View in: PubMed
    34. Muehlschlegel S, Sims JR. Dantrolene: mechanisms of neuroprotection and possible clinical applications in the neurointensive care unit. Neurocrit Care. 2009; 10(1):103-15. PMID: 18696266.
      View in: PubMed
    35. Muehlschlegel S, Rordorf G, Bodock M, Sims JR. Dantrolene mediates vasorelaxation in cerebral vasoconstriction: a case series. Neurocrit Care. 2009; 10(1):116-21. PMID: 18696267.
      View in: PubMed
    36. Muehlschlegel S, Goddeau RP, Sims JR. Teaching NeuroImage: Cerebral T-waves from an aneurysmal cardunculus compression. Neurology. 2008 Feb 12; 70(7):e28-9. PMID: 18268239.
      View in: PubMed
    37. Muehlschlegel S, Voetsch B, Singhal AB. CT angiography and CT perfusion in post-CEA hyperperfusion syndrome. Neurology. 2007 Apr 24; 68(17):1437. PMID: 17452594.
      View in: PubMed
    38. Muehlschlegel S, Dunser MW, Gabrielli A, Wenzel V, Layon AJ. Arginine vasopressin as a supplementary vasopressor in refractory hypertensive, hypervolemic, hemodilutional therapy in subarachnoid hemorrhage. Neurocrit Care. 2007; 6(1):3-10. PMID: 17356185.
      View in: PubMed
    39. Muehlschlegel S, Lobato EB. Con: all cardiac surgical patients should not have intraoperative cerebral oxygenation monitoring. J Cardiothorac Vasc Anesth. 2006 Aug; 20(4):613-5. PMID: 16884999.
      View in: PubMed
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