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Marc E. Uknis MD

TitleAdjunct Associate Professor
InstitutionUniversity of Massachusetts Medical School
DepartmentSurgery
AddressShire Pharmacuticals
300 Shire Way
Lexington MA 02421
Phone508-334-2023
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    Other Positions
    InstitutionUMMS - School of Medicine
    DepartmentMicrobiology and Physiological Systems

    InstitutionUMMS - School of Medicine
    DepartmentSurgery
    DivisionOrgan Transplantation


    Collapse Biography 
    Collapse education and training
    Temple University, Philadelphia, PA, United StatesBALiberal Arts and Sciences
    Temple University School of Medicine, Philadelphia, PA, United StatesMDMedicine

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Papanicolaou GA, Silveira FP, Langston AA, Pereira MR, Avery RK, Uknis M, Wijatyk A, Wu J, Boeckh M, Marty FM, Villano S. Maribavir for Refractory or Resistant Cytomegalovirus Infections in Hematopoietic-cell or Solid-organ Transplant Recipients: A Randomized, Dose-ranging, Double-blind, Phase 2 Study. Clin Infect Dis. 2018 Oct 16. PMID: 30329038.
      View in: PubMed
    2. Berger M, Liu M, Uknis ME, Koulmanda M. Alpha-1-antitrypsin in cell and organ transplantation. Am J Transplant. 2018 Apr 01. PMID: 29607607.
      View in: PubMed
    3. Montgomery RA, Orandi BJ, Racusen L, Jackson AM, Garonzik-Wang JM, Shah T, Woodle ES, Sommerer C, Fitts D, Rockich K, Zhang P, Uknis ME. Plasma-Derived C1 Esterase Inhibitor for Acute Antibody-Mediated Rejection Following Kidney Transplantation: Results of a Randomized Double-Blind Placebo-Controlled Pilot Study. Am J Transplant. 2016 May 16. PMID: 27184779.
      View in: PubMed
    4. Poppelaars F, Damman J, de Vrij EL, Burgerhof JG, Saye J, Daha MR, Leuvenink HG, Uknis ME, Seelen MA. New insight into the effects of heparinoids on complement inhibition by C1-inhibitor. Clin Exp Immunol. 2016 Jun; 184(3):378-88. PMID: 26874675; PMCID: PMC4872386 [Available on 06/01/17].
    5. DeZern AE, Uknis M, Yuan X, Mukhina GL, Varela J, Saye J, Pu J, Brodsky RA. Complement blockade with a C1 esterase inhibitor in paroxysmal nocturnal hemoglobinuria. Exp Hematol. 2014 Oct; 42(10):857-61.e1. PMID: 25034232.
      View in: PubMed
    6. Riedl MA, Lumry WR, Li HH, Craig TJ, Fitts D, Kalfus I, Uknis ME. Nanofiltered C1 esterase inhibitor for treatment of laryngeal attacks in patients with hereditary angioedema. Am J Rhinol Allergy. 2013 Nov-Dec; 27(6):517-21. PMID: 24274230.
      View in: PubMed
    7. Baker JW, Craig TJ, Riedl MA, Banerji A, Fitts D, Kalfus IN, Uknis ME. Nanofiltered C1 esterase inhibitor (human) for hereditary angioedema attacks in pregnant women. Allergy Asthma Proc. 2013 Mar-Apr; 34(2):162-9. PMID: 23484892.
      View in: PubMed
    8. Lumry W, Manning ME, Hurewitz DS, Davis-Lorton M, Fitts D, Kalfus IN, Uknis ME. Nanofiltered C1-esterase inhibitor for the acute management and prevention of hereditary angioedema attacks due to C1-inhibitor deficiency in children. J Pediatr. 2013 May; 162(5):1017-22.e1-2. PMID: 23312695.
      View in: PubMed
    9. Winston DJ, Saliba F, Blumberg E, Abouljoud M, Garcia-Diaz JB, Goss JA, Clough L, Avery R, Limaye AP, Ericzon BG, Navasa M, Troisi RI, Chen H, Villano SA, Uknis ME. Efficacy and safety of maribavir dosed at 100 mg orally twice daily for the prevention of cytomegalovirus disease in liver transplant recipients: a randomized, double-blind, multicenter controlled trial. Am J Transplant. 2012 Nov; 12(11):3021-30. PMID: 22947426.
      View in: PubMed
    10. Grant JA, White MV, Li HH, Fitts D, Kalfus IN, Uknis ME, Lumry WR. Preprocedural administration of nanofiltered C1 esterase inhibitor to prevent hereditary angioedema attacks. Allergy Asthma Proc. 2012 Jul-Aug; 33(4):348-53. PMID: 22856635.
      View in: PubMed
    11. Pavlakis M, Khwaja K, Mandelbrot D, Tang H, Whiting JW, Lorber MI, Gautam A, Johnson SR, Uknis ME. Renal allograft failure predictors after PAK transplantation: results from the New England Collaborative Association of Pancreas Programs. Transplantation. 2010 Jun 15; 89(11):1347-53. PMID: 20216481.
      View in: PubMed
    12. Bodonyi-Kovacs G, Putheti P, Marino M, Avihingsanon Y, Uknis ME, Monaco AP, Strom TB, Pavlakis M. Gene expression profiling of the donor kidney at the time of transplantation predicts clinical outcomes 2 years after transplantation. Hum Immunol. 2010 May; 71(5):451-5. PMID: 20156509.
      View in: PubMed
    13. Fishman JA, Emery V, Freeman R, Pascual M, Rostaing L, Schlitt HJ, Sgarabotto D, Torre-Cisneros J, Uknis ME. Cytomegalovirus in transplantation - challenging the status quo. Clin Transplant. 2007 Mar-Apr; 21(2):149-58. PMID: 17425738.
      View in: PubMed
    14. Weng FL, Patel AM, Wanchoo R, Brahmbhatt Y, Ribeiro K, Uknis ME, Mulgaonkar S, Mathis AS. Oral ganciclovir versus low-dose valganciclovir for prevention of cytomegalovirus disease in recipients of kidney and pancreas transplants. Transplantation. 2007 Feb 15; 83(3):290-6. PMID: 17297403.
      View in: PubMed
    15. Misra MV, Bhattacharya K, Nompleggi DJ, Uknis ME, Rastellini C, Cicalese L. Magnification endoscopy as a reliable tool for the early diagnosis of rejection in living related small bowel transplants: a case report. Transplant Proc. 2006 Jul-Aug; 38(6):1738-9. PMID: 16908267.
      View in: PubMed
    16. Asham E, Uknis ME, Rastellini C, Elias G, Cicalese L. Acellular dermal matrix provides a good option for abdominal wall closure following small bowel transplantation: a case report. Transplant Proc. 2006 Jul-Aug; 38(6):1770-1. PMID: 16908277.
      View in: PubMed
    17. Bradley SP, Pahari M, Uknis ME, Rastellini C, Cicalese L. Gene expression profiles characterize early graft response in living donor small bowel transplantation: a case report. Transplant Proc. 2006 Jul-Aug; 38(6):1742-3. PMID: 16908269.
      View in: PubMed
    18. Bradley SP, Pahari M, Elias G, Uknis ME, Misra MV, Rastellini C, Cicalese L. Intragraft gene expression profile during acute cellular rejection in clinical small bowel transplantation: a case report. Transplant Proc. 2006 Jul-Aug; 38(6):1740-1. PMID: 16908268.
      View in: PubMed
    19. Bradley SP, Rastellini C, da Costa MA, Kowalik TF, Bloomenthal AB, Brown M, Cicalese L, Basadonna GP, Uknis ME. Gene silencing in the endocrine pancreas mediated by short-interfering RNA. Pancreas. 2005 Nov; 31(4):373-9. PMID: 16258373.
      View in: PubMed
    20. Avihingsanon Y, Ma N, Pavlakis M, Chon WJ, Uknis ME, Monaco AP, Ferran C, Stillman I, Schachter AD, Mottley C, Zheng XX, Strom TB. On the intraoperative molecular status of renal allografts after vascular reperfusion and clinical outcomes. J Am Soc Nephrol. 2005 Jun; 16(6):1542-8. PMID: 15888558.
      View in: PubMed
    21. Canete JJ, Aidlen JT, Uknis ME, Cicalese L. Images of interest. Hepatobiliary and pancreatic: biliary cast syndrome. J Gastroenterol Hepatol. 2005 May; 20(5):791. PMID: 15853998.
      View in: PubMed
    22. Uknis ME. Prophylaxis of cytomegalovirus disease in transplant patients. Am J Health Syst Pharm. 2005 Apr 15; 62(8 Suppl 1):S3-6. PMID: 15821265.
      View in: PubMed
    23. Bradley SP, Kowalik TF, Rastellini C, da Costa MA, Bloomenthal AB, Cicalese L, Basadonna GP, Uknis ME. Successful incorporation of short-interfering RNA into islet cells by in situ perfusion. Transplant Proc. 2005 Jan-Feb; 37(1):233-6. PMID: 15808605.
      View in: PubMed
    24. Gill MB, Roecklein-Canfield J, Sage DR, Zambela-Soediono M, Longtine N, Uknis M, Fingeroth JD. EBV attachment stimulates FHOS/FHOD1 redistribution and co-aggregation with CD21: formin interactions with the cytoplasmic domain of human CD21. J Cell Sci. 2004 Jun 1; 117(Pt 13):2709-20. PMID: 15138285.
      View in: PubMed
    25. Akoad M, Giraldo M, Monaco AP, Hanto DW, Uknis ME. Enteric drainage of a pancreas allograft is safe for patients with celiac sprue. Clin Transplant. 2002 Oct; 16(5):387-8. PMID: 12225438.
      View in: PubMed
    26. Arrazola L, Sozen H, Humar A, Papalois V, Uknis M, Matas AJ. Increasing incidence of steroid resistant rejection in kidney transplantation. Transplant Proc. 2000 Nov; 32(7):1767. PMID: 11119926.
      View in: PubMed
    27. Arrazola L, Sozen H, Humar A, Papalois V, Uknis M, Matas AJ. Both immunologic and nonimmunologic factors are risks for long-term graft survival--a multivariate analysis. Transplant Proc. 2000 Nov; 32(7):1831. PMID: 11119957.
      View in: PubMed
    28. Humar A, Uknis M, Carlone-Jambor C, Gruessner RW, Dunn DL, Matas A. Cytomegalovirus disease recurrence after ganciclovir treatment in kidney and kidney-pancreas transplant recipients. Transplantation. 1999 Jan 15; 67(1):94-7. PMID: 9921803.
      View in: PubMed
    29. Zeevi A, Uknis ME, Spichty KJ, Tector M, Keenan RJ, Rinaldo C, Yousem S, Duncan S, Paradis I, Dauber J, et al. Proliferation of cytomegalovirus-primed lymphocytes in bronchoalveolar lavages from lung transplant patients. Transplantation. 1992 Oct; 54(4):635-9. PMID: 1329281.
      View in: PubMed
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