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Brian P O'Sullivan MD

TitleProfessor
InstitutionUniversity of Massachusetts Medical School
DepartmentPediatrics
AddressUniversity of Massachusetts Medical School
55 Lake Avenue North
Worcester MA 01655
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    Other Positions
    InstitutionUMMS - School of Medicine
    DepartmentPediatrics
    DivisionPediatric Pulmonology

    InstitutionUMMS - Graduate School of Biomedical Sciences
    DepartmentClinical Population Health Research


    Collapse Biography 
    Collapse education and training
    Dartmouth College, Hanover, NH, United StatesABBiology
    Dartmouth College, Hanover, NH, United StatesMDMedicine

    Collapse Overview 
    Collapse overview

    Research Interests

    1. Cystic fibrosis and platelet function (in conjunctionwith Dr. Alan Michelson)

    2. Cystic fibrosis and fatty acid metabolism (in conjunction with Steven Freedman from BI Deaconess)

    3. Cystic fibrosis and newborn screening

    Funding Sources

    1. Cystic Fibrosis Therapuetics Inc: The effects of infant formula supplemented with DHA on Cystic Fibrosis.

    2. Worcester Foundation for Biomedical Science: Platelet function in carriers of the CF mutation

    3. CF Foundation: Early Pseudomonas aeruginosa infection control (EPIC)




    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Billfalk-Kelly A, Yu E, Su J, O'Sullivan B, Waldron J, Ringash J, Bartlett E, Perez-Ordonez B, Weinreb I, Bayley A, Bratman SV, Cho J, Giuliani M, Hope A, Hosni A, Kim J, Hansen AR, de Almeida J, Tong L, Xu W, Huang SH. Radiologic Extranodal Extension Portends Worse Outcome in cN+ TNM8 Stage I Human Papillomavirus-Mediated Oropharyngeal Cancer. Int J Radiat Oncol Biol Phys. 2019 Apr 03. PMID: 30953712.
      View in: PubMed
    2. Guo Q, Lu T, Hui Huang S, O'Sullivan B, Zong J, Xiao Y, Xu W, Chen C, Qiu S, Xu L, Zheng W, Chen Y, Lin S, Pan J. Depicting distant metastatic risk by refined subgroups derived from the 8th edition nasopharyngeal carcinoma TNM. Oral Oncol. 2019 Apr; 91:113-120. PMID: 30926056.
      View in: PubMed
    3. Hall SF, Griffiths RJ, O'Sullivan B, Liu FF. The addition of chemotherapy to radiotherapy did not reduce the rate of distant metastases in low-risk HPV-related oropharyngeal cancer in a real-world setting. Head Neck. 2019 Feb 04. PMID: 30719797.
      View in: PubMed
    4. Hosni A, Huang SH, Chiu K, Xu W, Su J, Lu L, Bayley A, Bratman SV, Cho J, Giuliani M, Kim J, O'Sullivan B, Ringash J, Waldron J, Spreafico A, de Almeida JR, Chepeha DB, Irish JC, Goldstein DP, Hope A. Validation of distant metastases risk-groups in oral cavity squamous cell carcinoma patients treated with postoperative intensity-modulated radiotherapy. Radiother Oncol. 2019 May; 134:10-16. PMID: 31005202.
      View in: PubMed
    5. Lee VH, Kwong DL, Leung TW, Choi CW, O'Sullivan B, Lam KO, Lai V, Khong PL, Chan SK, Ng CY, Tong CC, Ho PP, Chan WL, Wong LS, Leung DK, Chan SY, So TH, Luk MY, Lee AW. The addition of pretreatment plasma Epstein-Barr virus DNA into the eighth edition of nasopharyngeal cancer TNM stage classification. Int J Cancer. 2019 Apr 01; 144(7):1713-1722. PMID: 30192385.
      View in: PubMed
    6. Lewis JS, Adelstein DJ, Agaimy A, Carlson DL, Faquin WC, Helliwell T, Hille J, Ng T, Nicholls JM, O'Sullivan B, Thompson LDR. Data Set for the Reporting of Carcinomas of the Nasopharynx and Oropharynx: Explanations and Recommendations of the Guidelines From the International Collaboration on Cancer Reporting. Arch Pathol Lab Med. 2019 Apr; 143(4):447-451. PMID: 30500294.
      View in: PubMed
    7. Hahn E, Huang SH, Hosni A, Razak AA, Jones RL, Dickson BC, Sturgis EM, Patel SG, O'Sullivan B. Ending 40 years of silence: Rationale for a new staging system for soft tissue sarcoma of the head and neck. Clin Transl Radiat Oncol. 2019 Feb; 15:13-19. PMID: 30582016.
      View in: PubMed
    8. Wong ET, Dmytriw AA, Yu E, Waldron J, Lu L, Fazelzad R, de Almeida JR, Veit-Haibach P, O'Sullivan B, Xu W, Huang SH. 18 F-FDG PET/CT for locoregional surveillance following definitive treatment of head and neck cancer: A meta-analysis of reported studies. Head Neck. 2019 Feb; 41(2):551-561. PMID: 30456825.
      View in: PubMed
    9. Chen YP, Wang YQ, Lv JW, Li YQ, Chua MLK, Le QT, Lee N, Colevas AD, Seiwert T, Hayes DN, Riaz N, Vermorken JB, O'Sullivan B, He QM, Yang XJ, Tang LL, Mao YP, Sun Y, Liu N, Ma J. Identification and validation of novel microenvironment-based immune molecular subgroups of head and neck squamous cell carcinoma: implications for immunotherapy. Ann Oncol. 2018 Nov 08. PMID: 30407504.
      View in: PubMed
    10. Welch ML, McIntosh C, Haibe-Kains B, Milosevic MF, Wee L, Dekker A, Huang SH, Purdie TG, O'Sullivan B, Aerts HJWL, Jaffray DA. Vulnerabilities of radiomic signature development: The need for safeguards. Radiother Oncol. 2019 Jan; 130:2-9. PMID: 30416044.
      View in: PubMed
    11. Karamboulas C, Bruce JP, Hope AJ, Meens J, Huang SH, Erdmann N, Hyatt E, Pereira K, Goldstein DP, Weinreb I, Su J, O'Sullivan B, Tiedemann R, Liu FF, Pugh TJ, Bratman SV, Xu W, Ailles L. Patient-Derived Xenografts for Prognostication and Personalized Treatment for Head and Neck Squamous Cell Carcinoma. Cell Rep. 2018 Oct 30; 25(5):1318-1331.e4. PMID: 30380421.
      View in: PubMed
    12. McDowell LJ, Ringash J, Xu W, Chan B, Lu L, Waldron J, Rock K, So N, Huang SH, Giuliani M, Hope A, O'Sullivan B, Bratman SV, Cho J, Kim J, Jang R, Bayley A, Bernstein LJ. A cross sectional study in cognitive and neurobehavioral impairment in long-term nasopharyngeal cancer survivors treated with intensity-modulated radiotherapy. Radiother Oncol. 2019 Feb; 131:179-185. PMID: 30279047.
      View in: PubMed
    13. Huang SH, Hahn E, Tsang RK, Chen ZJ, O'Sullivan B. The interplay of IMRT and transoral surgery in HPV-mediated oropharyngeal cancer: Getting the balance right. Oral Oncol. 2018 Nov; 86:171-180. PMID: 30409297.
      View in: PubMed
    14. Hosni A, Huang SH, Chiu K, Xu W, Su J, Bayley A, Bratman SV, Cho J, Giuliani M, Kim J, O'Sullivan B, Ringash J, Waldron J, Spreafico A, Yu E, de Almeida JR, Monteiro E, Chepeha DB, Irish JC, Goldstein DP, Hope A. Predictors of Early Recurrence Prior to Planned Postoperative Radiation Therapy for Oral Cavity Squamous Cell Carcinoma and Outcomes Following Salvage Intensified Radiation Therapy. Int J Radiat Oncol Biol Phys. 2019 Feb 01; 103(2):363-373. PMID: 30244160.
      View in: PubMed
    15. Liu X, Zhang Y, Tang LL, Le QT, Chua MLK, Wee JTS, Lee NY, O'Sullivan B, Lee AWM, Sun Y, Ma J. Characteristics of Radiotherapy Trials Compared With Other Oncological Clinical Trials in the Past 10 Years. JAMA Oncol. 2018 Aug 01; 4(8):1073-1079. PMID: 29799987.
      View in: PubMed
    16. O'Sullivan B, Waldron J. Preoperative Radiation Therapy for Locally Advanced Sinus Malignancies. Int J Radiat Oncol Biol Phys. 2018 Jul 15; 101(4):763-764. PMID: 29976484.
      View in: PubMed
    17. Gundle KR, Griffin AM, Dickson BC, Chung PW, Catton CN, O'Sullivan B, Wunder JS, Ferguson PC. Reply to A. Levy et al. J Clin Oncol. 2018 Jun 07; JCO2018787325. PMID: 29878865.
      View in: PubMed
    18. McDowell LJ, Rock K, Xu W, Chan B, Waldron J, Lu L, Ezzat S, Pothier D, Bernstein LJ, So N, Huang SH, Giuliani M, Hope A, O'Sullivan B, Bratman SV, Cho J, Kim J, Jang R, Bayley A, Ringash J. Long-Term Late Toxicity, Quality of Life, and Emotional Distress in Patients With Nasopharyngeal Carcinoma Treated With Intensity Modulated Radiation Therapy. Int J Radiat Oncol Biol Phys. 2018 10 01; 102(2):340-352. PMID: 30191868.
      View in: PubMed
    19. Horowitz G, Hosni A, Yu E, Xu W, Lu L, Au M, Dixon PR, Brown D, Chepeha DB, Gilbert RW, Goldstein DP, Gullane PJ, Irish JC, Bayley A, Cho J, Giuliani M, Huang SH, Hope A, Kim J, O'Sullivan B, Ringash J, Waldron J, Weinreb I, Perez-Ordonez B, Bratman SV, de Almeida JR. Prevalence, prognosis, and treatment implications of retropharyngeal nodes in unknown primary head and neck carcinoma. Oral Oncol. 2018 Jul; 82:162-167. PMID: 29909891.
      View in: PubMed
    20. Lydiatt W, O'Sullivan B, Patel S. Major Changes in Head and Neck Staging for 2018. Am Soc Clin Oncol Educ Book. 2018 May 23; 38:505-514. PMID: 30231400.
      View in: PubMed
    21. Almulla A, Noel CW, Lu L, Xu W, O'Sullivan B, Goldstein DP, Hope A, Perez-Ordonez B, Weinreb I, Irish J, Gullane P, Chepeha D, Tong L, Yu E, Huang SH. Radiologic-Pathologic Correlation of Extranodal Extension in Patients With Squamous Cell Carcinoma of the Oral Cavity: Implications for Future Editions of the TNM Classification. Int J Radiat Oncol Biol Phys. 2018 Nov 15; 102(4):698-708. PMID: 29970315.
      View in: PubMed
    22. Principe S, Mejia-Guerrero S, Ignatchenko V, Sinha A, Ignatchenko A, Shi W, Pereira K, Su S, Huang SH, O'Sullivan B, Xu W, Goldstein DP, Weinreb I, Ailles L, Liu FF, Kislinger T. Proteomic Analysis of Cancer-Associated Fibroblasts Reveals a Paracrine Role for MFAP5 in Human Oral Tongue Squamous Cell Carcinoma. J Proteome Res. 2018 06 01; 17(6):2045-2059. PMID: 29681158.
      View in: PubMed
    23. Rock K, Huang SH, Tiong A, Lu L, Xu W, Ringash J, Bratman SV, Tong L, Chan B, Cho J, Giuliani M, Hope A, Bayley A, Kim J, de Almeida JR, O'Sullivan B, Waldron J. Partial Laryngeal IMRT for T2N0 Glottic Cancer: Impact of Image Guidance and Radiation Therapy Intensification. Int J Radiat Oncol Biol Phys. 2018 Nov 15; 102(4):941-949. PMID: 29730062.
      View in: PubMed
    24. Kwan JYY, Su J, Huang SH, Ghoraie LS, Xu W, Chan B, Yip KW, Giuliani M, Bayley A, Kim J, Hope AJ, Ringash J, Cho J, McNiven A, Hansen A, Goldstein D, de Almeida JR, Aerts HJ, Waldron JN, Haibe-Kains B, O'Sullivan B, Bratman SV, Liu FF. Radiomic Biomarkers to Refine Risk Models for Distant Metastasis in HPV-related Oropharyngeal Carcinoma. Int J Radiat Oncol Biol Phys. 2018 Nov 15; 102(4):1107-1116. PMID: 29506884.
      View in: PubMed
    25. Gundle KR, Kafchinski L, Gupta S, Griffin AM, Dickson BC, Chung PW, Catton CN, O'Sullivan B, Wunder JS, Ferguson PC. Analysis of Margin Classification Systems for Assessing the Risk of Local Recurrence After Soft Tissue Sarcoma Resection. J Clin Oncol. 2018 Mar 01; 36(7):704-709. PMID: 29346043.
      View in: PubMed
    26. Huang SH, O'Sullivan B, Waldron J. The Current State of Biological and Clinical Implications of Human Papillomavirus-Related Oropharyngeal Cancer. Semin Radiat Oncol. 2018 01; 28(1):17-26. PMID: 29173751.
      View in: PubMed
    27. Laliberte C, Leong IT, Holmes H, Monteiro EA, O'Sullivan B, Dickson BC. Sclerosing Epithelioid Fibrosarcoma of the Jaw: Late Recurrence from a Low Grade Fibromyxoid Sarcoma. Head Neck Pathol. 2018 Dec; 12(4):619-622. PMID: 29274042.
      View in: PubMed
    28. Zer A, Pond GR, Razak ARA, Tirona K, Gan HK, Chen EX, O'Sullivan B, Waldron J, Goldstein DP, Weinreb I, Hope AJ, Kim JJ, Chan KKW, Chan AK, Siu LL, Bernstein LJ. Association of Neurocognitive Deficits With Radiotherapy or Chemoradiotherapy for Patients With Head and Neck Cancer. JAMA Otolaryngol Head Neck Surg. 2017 Nov 22. PMID: 29167901.
      View in: PubMed
    29. Lalani N, Huang SH, Rotstein C, Yu E, Irish J, O'Sullivan B. Skull base or cervical vertebral osteomyelitis following chemoradiotherapy for pharyngeal carcinoma: A serious but treatable complication. Clin Transl Radiat Oncol. 2018 Jan; 8:40-44. PMID: 29594240.
      View in: PubMed
    30. Foreman A, Lee DJ, McMullen C, de Almeida J, Muhanna N, Gama RR, Giuliani M, Liu G, Bratman SV, Huang SH, O'Sullivan B, Song Y, Xu W, Goldstein DP. Impact of Type 2 Diabetes Mellitus on Survival in Head and Neck Squamous Cell Carcinoma. Otolaryngol Head Neck Surg. 2017 10; 157(4):657-663. PMID: 28849730.
      View in: PubMed
    31. Hall SF, Liu FF, O'Sullivan B, Shi W, Rohland S, Griffiths R, Groome P. Did the addition of concurrent chemotherapy to conventional radiotherapy improve survival for patients with HPV+ve and HPV-ve Oropharynx cancer? A population-based study. Br J Cancer. 2017 Oct 10; 117(8):1105-1112. PMID: 28829763.
      View in: PubMed
    32. Habbous S, Chu KP, Lau H, Schorr M, Belayneh M, Ha MN, Murray S, O'Sullivan B, Huang SH, Snow S, Parliament M, Hao D, Cheung WY, Xu W, Liu G. Human papillomavirus in oropharyngeal cancer in Canada: analysis of 5 comprehensive cancer centres using multiple imputation. CMAJ. 2017 Aug 14; 189(32):E1030-E1040. PMID: 28808115.
      View in: PubMed
    33. Hosni A, McMullen C, Huang SH, Xu W, Su J, Bayley A, Bratman SV, Cho J, Giuliani M, Kim J, Ringash J, Waldron J, Spreafico A, Weinreb I, de Almeida JR, Brown DH, Irish JC, O'Sullivan B, Goldstein DP, Hope A. Lymph node ratio relationship to regional failure and distant metastases in oral cavity cancer. Radiother Oncol. 2017 08; 124(2):225-231. PMID: 28838425.
      View in: PubMed
    34. Rishi A, Hui Huang S, O'Sullivan B, Goldstein DP, Lu L, Ringash J, Waldron J, Wells W, Sun A, Hope A, Chung P, Giuliani M, Spreafico A, Tong L, Xu W, Bayley A. Outcome following radiotherapy for head and neck basal cell carcinoma with 'aggressive' features. Oral Oncol. 2017 09; 72:157-164. PMID: 28797452.
      View in: PubMed
    35. O'Sullivan B, Brierley J, Byrd D, Bosman F, Kehoe S, Kossary C, Piñeros M, Van Eycken E, Weir HK, Gospodarowicz M. The TNM classification of malignant tumours-towards common understanding and reasonable expectations. Lancet Oncol. 2017 07; 18(7):849-851. PMID: 28677562.
      View in: PubMed
    36. Huang SH, O'Sullivan B. Overview of the 8th Edition TNM Classification for Head and Neck Cancer. Curr Treat Options Oncol. 2017 07; 18(7):40. PMID: 28555375.
      View in: PubMed
    37. Caparrotti F, Huang SH, Lu L, Bratman SV, Ringash J, Bayley A, Cho J, Giuliani M, Kim J, Waldron J, Hansen A, Tong L, Xu W, O'Sullivan B, Wood R, Goldstein D, Hope A. Osteoradionecrosis of the mandible in patients with oropharyngeal carcinoma treated with intensity-modulated radiotherapy. Cancer. 2017 Oct 01; 123(19):3691-3700. PMID: 28608925.
      View in: PubMed
    38. Chan MW, Yu E, Bartlett E, O'Sullivan B, Su J, Waldron J, Ringash J, Bratman SV, Chen YA, Irish J, Kim J, Gullane P, Gilbert R, Chepeha D, Perez-Ordonez B, Weinreb I, Hansen A, Tong L, Xu W, Huang SH. Morphologic and topographic radiologic features of human papillomavirus-related and -unrelated oropharyngeal carcinoma. Head Neck. 2017 08; 39(8):1524-1534. PMID: 28580605.
      View in: PubMed
    39. Bernstein JM, Irish JC, Brown DH, Goldstein D, Chung P, Razak ARA, Catton C, Gilbert RW, Gullane PJ, O'Sullivan B. Survival outcomes for cutaneous angiosarcoma of the scalp versus face. Head Neck. 2017 06; 39(6):1205-1211. PMID: 28398688.
      View in: PubMed
    40. Hosni A, Huang SH, Xu W, Su J, Bayley A, Bratman SV, Cho J, Giuliani M, Kim J, Ringash J, Waldron J, Spreafico A, De Almeidad J, O'Sullivan B, Goldstein D, Hope A. Distant Metastases Following Postoperative Intensity-Modulated Radiotherapy for Oral Cavity Squamous Cell Carcinoma. JAMA Otolaryngol Head Neck Surg. 2017 04 01; 143(4):368-375. PMID: 28033442.
      View in: PubMed
    41. Dickie C, Parent A, Griffin AM, Wunder J, Ferguson P, Chung PW, Craig T, Sharpe M, Becker N, Shultz D, Catton CN, O'Sullivan B. The value of adaptive preoperative radiotherapy in management of soft tissue sarcoma. Radiother Oncol. 2017 03; 122(3):458-463. PMID: 28169043.
      View in: PubMed
    42. Huang SH, Waldron J, Bratman SV, Su J, Kim J, Bayley A, Cho J, Giuliani M, Hope A, Ringash J, Hansen A, de Almeida JR, Goldstein D, Perez-Ordonez B, Weinreb I, Tong L, Xu W, O'Sullivan B. Re-evaluation of Ipsilateral Radiation for T1-T2N0-N2b Tonsil Carcinoma at the Princess Margaret Hospital in the Human Papillomavirus Era, 25 Years Later. Int J Radiat Oncol Biol Phys. 2017 05 01; 98(1):159-169. PMID: 28258895.
      View in: PubMed
    43. Ringash J, Waldron JN, Siu LL, Martino R, Winquist E, Wright JR, Nabid A, Hay JH, Hammond A, Sultanem K, Hotte S, Leong C, El-Gayed AA, Naz F, Ramchandar K, Owen TE, Montenegro A, O'Sullivan B, Chen BE, Parulekar WR. Quality of life and swallowing with standard chemoradiotherapy versus accelerated radiotherapy and panitumumab in locoregionally advanced carcinoma of the head and neck: A phase III randomised trial from the Canadian Cancer Trials Group (HN.6). Eur J Cancer. 2017 02; 72:192-199. PMID: 28040660.
      View in: PubMed
    44. Siu LL, Waldron JN, Chen BE, Winquist E, Wright JR, Nabid A, Hay JH, Ringash J, Liu G, Johnson A, Shenouda G, Chasen M, Pearce A, Butler JB, Breen S, Chen EX, FitzGerald TJ, Childs TJ, Montenegro A, O'Sullivan B, Parulekar WR. Effect of Standard Radiotherapy With Cisplatin vs Accelerated Radiotherapy With Panitumumab in Locoregionally Advanced Squamous Cell Head and Neck Carcinoma: A Randomized Clinical Trial. JAMA Oncol. 2016 Dec 08. PMID: 27930762.
      View in: PubMed
    45. Hosni A, Dixon PR, Rishi A, Au M, Xu W, Song Y, Chepeha DB, Goldstein DP, Huang SH, Kim J, O'Sullivan B, Waldron J, Bratman SV, de Almeida JR. Radiotherapy Characteristics and Outcomes for Head and Neck Carcinoma of Unknown Primary vs T1 Base-of-Tongue Carcinoma. JAMA Otolaryngol Head Neck Surg. 2016 12 01; 142(12):1208-1215. PMID: 27812692.
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    46. Bauman JE, Cohen E, Ferris RL, Adelstein DJ, Brizel DM, Ridge JA, O'Sullivan B, Burtness BA, Butterfield LH, Carson WE, Disis ML, Fox BA, Gajewski TF, Gillison ML, Hodge JW, Le QT, Raben D, Strome SE, Lynn J, Malik S. Immunotherapy of head and neck cancer: Emerging clinical trials from a National Cancer Institute Head and Neck Cancer Steering Committee Planning Meeting. Cancer. 2017 Apr 01; 123(7):1259-1271. PMID: 27906454.
      View in: PubMed
    47. Caparrotti F, O'Sullivan B, Bratman SV, Ringash J, Lu L, Bayley A, Cho J, Giuliani M, Hope A, Kim J, Waldron J, Hansen A, Goldstein D, Perez-Ordonez B, Weinreb I, Tong L, Song Y, Xu W, Huang SH. Exploring the Impact of Human Papillomavirus Status, Comorbidity, Polypharmacy, and Treatment Intensity on Outcome of Elderly Oropharyngeal Cancer Patients Treated With Radiation Therapy With or Without Chemotherapy. Int J Radiat Oncol Biol Phys. 2017 07 15; 98(4):858-867. PMID: 28258893.
      View in: PubMed
    48. Rodin D, Caulley L, Burger E, Kim J, Johnson-Obaseki S, Palma D, Louie AV, Hansen A, O'Sullivan B. Cost-Effectiveness Analysis of Radiation Therapy Versus Transoral Robotic Surgery for Oropharyngeal Squamous Cell Carcinoma. Int J Radiat Oncol Biol Phys. 2017 03 15; 97(4):709-717. PMID: 28244405.
      View in: PubMed
    49. Brierley J, Gospodarowicz M, O'Sullivan B. The principles of cancer staging. Ecancermedicalscience. 2016; 10:ed61. PMID: 28101141.
      View in: PubMed
    50. Wilschanski M, Yaakov Y, Omari I, Zaman M, Martin CR, Cohen-Cymberknoh M, Shoseyov D, Kerem E, Dasilva D, Sheth S, Uluer A, O'Sullivan BP, Freedman S. Comparison of Nasal Potential Difference and Intestinal Current Measurements as Surrogate Markers for CFTR Function. J Pediatr Gastroenterol Nutr. 2016 Nov; 63(5):e92-e97. PMID: 27496797.
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    51. O'Sullivan BP. Importance of Off-Label Options for Treating Serious Lung Diseases. Ann Am Thorac Soc. 2016 Nov; 13(11):1879-1880. PMID: 27831808.
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    52. Spreafico A, Huang SH, Xu W, Granata R, Liu CS, Waldron JN, Chen E, Ringash J, Bayley A, Chan KK, Hope AJ, Cho J, Razak AA, Hansen A, Jang R, Perez-Ordonez B, Weinreb I, Bossi P, Orlandi E, Licitra LF, Song Y, O'Sullivan B, Siu LL, Kim J. Impact of cisplatin dose intensity on human papillomavirus-related and -unrelated locally advanced head and neck squamous cell carcinoma. Eur J Cancer. 2016 11; 67:174-182. PMID: 27669504.
      View in: PubMed
    53. Haughey BH, Sinha P, Kallogjeri D, Goldberg RL, Lewis JS, Piccirillo JF, Jackson RS, Moore EJ, Brandwein-Gensler M, Magnuson SJ, Carroll WR, Jones TM, Wilkie MD, Lau A, Upile NS, Sheard J, Lancaster J, Tandon S, Robinson M, Husband D, Ganly I, Shah JP, Brizel DM, O'Sullivan B, Ridge JA, Lydiatt WM. Pathology-based staging for HPV-positive squamous carcinoma of the oropharynx. Oral Oncol. 2016 11; 62:11-19. PMID: 27865363.
      View in: PubMed
    54. Waldron JN, O'Sullivan B. The Challenges of Treatment Adaptation and De-intensification in Human Papillomavirus-Positive Oropharyngeal Cancer: The Difficult Journey Back. Int J Radiat Oncol Biol Phys. 2016 09 01; 96(1):18-20. PMID: 27511843.
      View in: PubMed
    55. Tiong SS, Dickie C, Haas RL, O'Sullivan B. The role of radiotherapy in the management of localized soft tissue sarcomas. Cancer Biol Med. 2016 Sep; 13(3):373-383. PMID: 27807504.
      View in: PubMed
    56. Pan JJ, Ng WT, Zong JF, Lee SW, Choi HC, Chan LL, Lin SJ, Guo QJ, Sze HC, Chen YB, Xiao YP, Kan WK, O'Sullivan B, Xu W, Le QT, Glastonbury CM, Colevas AD, Weber RS, Lydiatt W, Shah JP, Lee AW. Prognostic nomogram for refining the prognostication of the proposed 8th edition of the AJCC/UICC staging system for nasopharyngeal cancer in the era of intensity-modulated radiotherapy. Cancer. 2016 Nov 15; 122(21):3307-3315. PMID: 27434142.
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    57. Prawira A, Brana-Garcia I, Spreafico A, Hope A, Waldron J, Razak AR, Chen EX, Jang R, O'Sullivan B, Giuliani M, Bayley A, Cho J, Wang L, Perez-Ordonez B, Weinreb I, Siu LL, Hansen AR. Phase I trial of dacomitinib, a pan-human epidermal growth factor receptor (HER) inhibitor, with concurrent radiotherapy and cisplatin in patients with locoregionally advanced squamous cell carcinoma of the head and neck (XDC-001). Invest New Drugs. 2016 10; 34(5):575-83. PMID: 27289242.
      View in: PubMed
    58. Bratman SV, Bruce JP, O'Sullivan B, Pugh TJ, Xu W, Yip KW, Liu FF. Human Papillomavirus Genotype Association With Survival in Head and Neck Squamous Cell Carcinoma. JAMA Oncol. 2016 Jun 01; 2(6):823-6. PMID: 27010835.
      View in: PubMed
    59. Azad AK, Bairati I, Qiu X, Girgis H, Cheng L, Waggott D, Cheng D, Mirshams M, Ho J, Fortin A, Vigneault E, Huang SH, O'Sullivan B, Waldron J, Boutros PC, Goldstein D, Meyer F, Xu W, Liu G. A genome-wide association study of non-HPV-related head and neck squamous cell carcinoma identifies prognostic genetic sequence variants in the MAP-kinase and hormone pathways. Cancer Epidemiol. 2016 06; 42:173-80. PMID: 27173062.
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    60. Truong Lam M, O'Sullivan B, Gullane P, Huang SH. Challenges in establishing the diagnosis of human papillomavirus-related oropharyngeal carcinoma. Laryngoscope. 2016 10; 126(10):2270-5. PMID: 27074870.
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    61. Ringash J, Fisher R, Peters L, Trotti A, O'Sullivan B, Corry J, Kenny L, Nuyts S, Wratten C, Rischin D. Effect of p16 Status on the Quality-of-Life Experience During Chemoradiation for Locally Advanced Oropharyngeal Cancer: A Substudy of Randomized Trial Trans-Tasman Radiation Oncology Group (TROG) 02.02 (HeadSTART). Int J Radiat Oncol Biol Phys. 2017 03 15; 97(4):678-686. PMID: 27209505.
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    62. Dixon PR, Au M, Hosni A, Perez-Ordonez B, Weinreb I, Xu W, Song Y, Huang SH, O'Sullivan B, Goldstein DP, de Almeida JR. Impact of p16 expression, nodal status, and smoking on oncologic outcomes of patients with head and neck unknown primary squamous cell carcinoma. Head Neck. 2016 09; 38(9):1347-53. PMID: 27002481.
      View in: PubMed
    63. O'Sullivan B, Huang SH, Su J, Garden AS, Sturgis EM, Dahlstrom K, Lee N, Riaz N, Pei X, Koyfman SA, Adelstein D, Burkey BB, Friborg J, Kristensen CA, Gothelf AB, Hoebers F, Kremer B, Speel EJ, Bowles DW, Raben D, Karam SD, Yu E, Xu W. Development and validation of a staging system for HPV-related oropharyngeal cancer by the International Collaboration on Oropharyngeal cancer Network for Staging (ICON-S): a multicentre cohort study. Lancet Oncol. 2016 04; 17(4):440-451. PMID: 26936027.
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    64. Vengalil S, Giuliani ME, Huang SH, McNiven A, Song Y, Xu W, Chan B, Hope A, Cho J, Bayley A, Ringash J, Goldstein D, Razak A, Irish J, Gilbert R, Gullane P, Waldron J, Kim J, O'Sullivan B. Clinical outcomes in patients with T4 laryngeal cancer treated with primary radiotherapy versus primary laryngectomy. Head Neck. 2016 04; 38 Suppl 1:E2035-40. PMID: 26828197.
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    65. Hosni A, Huang SH, Goldstein D, Xu W, Chan B, Hansen A, Weinreb I, Bratman SV, Cho J, Giuliani M, Hope A, Kim J, O'Sullivan B, Waldron J, Ringash J. Outcomes and prognostic factors for major salivary gland carcinoma following postoperative radiotherapy. Oral Oncol. 2016 Mar; 54:75-80. PMID: 26723908.
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    238. Borden EC, Baker LH, Bell RS, Bramwell V, Demetri GD, Eisenberg BL, Fletcher CD, Fletcher JA, Ladanyi M, Meltzer P, O'Sullivan B, Parkinson DR, Pisters PW, Saxman S, Singer S, Sundaram M, van Oosterom AT, Verweij J, Waalen J, Weiss SW, Brennan MF. Soft tissue sarcomas of adults: state of the translational science. Clin Cancer Res. 2003 Jun; 9(6):1941-56. PMID: 12796356.
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    242. Quaine J, Eyeson-Annan M, Baker D, O'Sullivan B, Williamson M, Jorm L. Report on the development of the New South Wales Child Health Survey 2001. N S W Public Health Bull. 2003 Feb; 14 Suppl 1:1-71. PMID: 12555105.
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    243. Gerrand CH, Bell RS, Wunder JS, Kandel RA, O'Sullivan B, Catton CN, Griffin AM, Davis AM. The influence of anatomic location on outcome in patients with soft tissue sarcoma of the extremity. Cancer. 2003 Jan 15; 97(2):485-92. PMID: 12518373.
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    244. O'Sullivan B, Shah J. New TNM staging criteria for head and neck tumors. Semin Surg Oncol. 2003; 21(1):30-42. PMID: 12923914.
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    249. Warde P, O'Sullivan B, Aslanidis J, Kroll B, Lockwood G, Waldron J, Payne D, Bayley A, Ringash J, Kim J, Liu FF, Maxymiw W, Sprague S, Cummings BJ. A Phase III placebo-controlled trial of oral pilocarpine in patients undergoing radiotherapy for head-and-neck cancer. Int J Radiat Oncol Biol Phys. 2002 Sep 01; 54(1):9-13. PMID: 12182969.
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    250. O'Sullivan BP. Risks and complications of nonbronchoscopic bronchoalveolar lavage in a pediatric intensive care unit. Pediatr Pulmonol. 2002 Jul; 34(1):87-8; author reply 88. PMID: 12112804.
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    252. Chow E, Payne D, O'Sullivan B, Pintilie M, Liu FF, Waldron J, Warde P, Cummings B. Radiotherapy alone in patients with advanced nasopharyngeal cancer: comparison with an intergroup study. Is combined modality treatment really necessary? Radiother Oncol. 2002 Jun; 63(3):269-74. PMID: 12142090.
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    253. Groome PA, Schulze K, Boysen M, Hall SF, Mackillop WJ, O'Sullivan B, Irish JC, Warde PR, Schneider KM, Mackenzie RG, Hodson DI, Hammond JA, Gulavita SP, Eapen LJ, Dixon PF, Bissett RJ. A comparison of published head and neck stage groupings in laryngeal cancer using data from two countries. J Clin Epidemiol. 2002 Jun; 55(6):533-44. PMID: 12063095.
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    254. Jones JJ, Catton CN, O'Sullivan B, Couture J, Heisler RL, Kandel RA, Swallow CJ. Initial results of a trial of preoperative external-beam radiation therapy and postoperative brachytherapy for retroperitoneal sarcoma. Ann Surg Oncol. 2002 May; 9(4):346-54. PMID: 11986186.
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    256. Paisley S, Warde PR, O'Sullivan B, Waldron J, Gullane PJ, Payne D, Liu FF, Bayley A, Ringash J, Cummings BJ. Results of radiotherapy for primary subglottic squamous cell carcinoma. Int J Radiat Oncol Biol Phys. 2002 Apr 1; 52(5):1245-50. PMID: 11955735.
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    257. Tsang RW, Gospodarowicz MK, O'Sullivan B. Staging and management of localized non-Hodgkin's lymphomas: variations among experts in radiation oncology. Int J Radiat Oncol Biol Phys. 2002 Mar 01; 52(3):643-51. PMID: 11849785.
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    258. Brierley JD, Catton PA, O'Sullivan B, Dancey JE, Dowling AJ, Irish JC, McGowan TS, Sturgeon JF, Swallow CJ, Rodrigues GB, Panzarella T. Accuracy of recorded tumor, node, and metastasis stage in a comprehensive cancer center. J Clin Oncol. 2002 Jan 15; 20(2):413-9. PMID: 11786568.
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    263. Joseph PM, O'Sullivan BP, Lapey A, Dorkin H, Oren J, Balfour R, Perricone MA, Rosenberg M, Wadsworth SC, Smith AE, St George JA, Meeker DP. Aerosol and lobar administration of a recombinant adenovirus to individuals with cystic fibrosis. I. Methods, safety, and clinical implications. Hum Gene Ther. 2001 Jul 20; 12(11):1369-82. PMID: 11485629.
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    265. Feingold B, O'Sullivan B, del Nido P, Pollack P. Situs inversus totalis and corrected transposition of the great arteries [I,D,D] in association with a previously unreported vascular ring. Pediatr Cardiol. 2001 Jul-Aug; 22(4):338-42. PMID: 11455405.
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    266. Lewis SJ, Wunder JS, Couture J, Davis M, Catton C, Kandel RA, Kotwall C, O'Sullivan B, Bell RS. Soft tissue sarcomas involving the pelvis. J Surg Oncol. 2001 May; 77(1):8-14; discussion 15. PMID: 11344473.
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    270. Barbera L, Groome PA, Mackillop WJ, Schulze K, O'Sullivan B, Irish JC, Warde PR, Schneider KM, Mackenzie RG, Hodson DI, Hammond JA, Gulavita SP, Eapen LJ, Dixon PF, Bissett RJ. The role of computed tomography in the T classification of laryngeal carcinoma. Cancer. 2001 Jan 15; 91(2):394-407. PMID: 11180087.
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    271. Crosby JA, Catton CN, Davis A, Couture J, O'Sullivan B, Kandel R, Swallow CJ. Malignant gastrointestinal stromal tumors of the small intestine: a review of 50 cases from a prospective database. Ann Surg Oncol. 2001 Jan-Feb; 8(1):50-9. PMID: 11206225.
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    272. Cheifetz R, Catton CN, Kandel R, O'Sullivan B, Couture J, Swallow CJ. Recent progress in the management of retroperitoneal sarcoma. Sarcoma. 2001; 5(1):17-26. PMID: 18521304; PMCID: PMC2395448.
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    274. Ringash J, Redelmeier DA, O'Sullivan B, Bezjak A. Quality of life and utility in irradiated laryngeal cancer patients. Int J Radiat Oncol Biol Phys. 2000 Jul 01; 47(4):875-81. PMID: 10863055.
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    275. Warde P, Kroll B, O'Sullivan B, Aslanidis J, Tew-George E, Waldron J, Maxymiw W, Liu FF, Payne D, Cummings B. A phase II study of Biotene in the treatment of postradiation xerostomia in patients with head and neck cancer. Support Care Cancer. 2000 May; 8(3):203-8. PMID: 10789961.
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    277. Davis AM, Sennik S, Griffin AM, Wunder JS, O'Sullivan B, Catton CN, Bell RS. Predictors of functional outcomes following limb salvage surgery for lower-extremity soft tissue sarcoma. J Surg Oncol. 2000 Apr; 73(4):206-11. PMID: 10797333.
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    278. McGowan TS, Cummings BJ, O'Sullivan B, Catton CN, Miller N, Panzarella T. An analysis of 78 breast sarcoma patients without distant metastases at presentation. Int J Radiat Oncol Biol Phys. 2000 Jan 15; 46(2):383-90. PMID: 10661345.
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    280. Kandel RA, Bell RS, Wunder JS, O'Sullivan B, Catton CN, White LM, Davis AM. Comparison between a 2- and 3-grade system in predicting metastatic-free survival in extremity soft-tissue sarcoma. J Surg Oncol. 1999 Oct; 72(2):77-82. PMID: 10518103.
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    282. Wylie JP, O'Sullivan B, Catton C, Gutierrez E. Contemporary radiotherapy for soft tissue sarcoma. Semin Surg Oncol. 1999 Jul-Aug; 17(1):33-46. PMID: 10402636.
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    283. Catton C, Jewett M, O'Sullivan B, Kandel R. Paratesticular sarcoma: failure patterns after definitive local therapy. J Urol. 1999 Jun; 161(6):1844-7. PMID: 10332450.
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    284. Verschuur HP, Irish JC, O'Sullivan B, Goh C, Gullane PJ, Pintilie M. A matched control study of treatment outcome in young patients with squamous cell carcinoma of the head and neck. Laryngoscope. 1999 Feb; 109(2 Pt 1):249-58. PMID: 10890775.
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    285. O'Sullivan B, Gospodarowicz M, Mackillop WJ, Evans WK, Whylie B, Ashbury FD. The consultation to develop a national strategy for cancer staging in Canada. Cancer Prev Control. 1998 Dec; 2(6):287-94. PMID: 10470458.
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    286. O'Sullivan B, Gospodarowicz M, Ashbury FD, Kralj B, Kaegi E. Survey of Canadian doctors' attitudes to cancer staging. Cancer Prev Control. 1998 Dec; 2(6):278-86. PMID: 10470457.
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    287. Curran AJ, Gullane PJ, Waldron J, Irish J, Brown D, O'Sullivan B, Cummings B. Surgical salvage after failed radiation for paranasal sinus malignancy. Laryngoscope. 1998 Nov; 108(11 Pt 1):1618-22. PMID: 9818815.
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    288. McLean M, Chow E, O'Sullivan B, Munro A, Leung PM, Loblaw DA, Panzarella T. Re-irradiation for locally recurrent nasopharyngeal carcinoma. Radiother Oncol. 1998 Aug; 48(2):209-11. PMID: 9783894.
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    289. Angelov L, Davis A, O'Sullivan B, Bell R, Guha A. Neurogenic sarcomas: experience at the University of Toronto. Neurosurgery. 1998 Jul; 43(1):56-64; discussion 64-5. PMID: 9657189.
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    290. Warde P, O'Sullivan B, Bristow RG, Panzarella T, Keane TJ, Gullane PJ, Witterick IP, Payne D, Liu FF, McLean M, Waldron J, Cummings BJ. T1/T2 glottic cancer managed by external beam radiotherapy: the influence of pretreatment hemoglobin on local control. Int J Radiat Oncol Biol Phys. 1998 May 01; 41(2):347-53. PMID: 9607350.
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    291. Waldron JN, O'Sullivan B, Warde P, Gullane P, Lui FF, Payne D, Cummings B. Ethmoid sinus cancer: twenty-nine cases managed with primary radiation therapy. Int J Radiat Oncol Biol Phys. 1998 May 01; 41(2):361-9. PMID: 9607352.
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    292. O'Sullivan BP, Frassica JJ, Rayder SM. Tracheal bronchus: a cause of prolonged atelectasis in intubated children. Chest. 1998 Feb; 113(2):537-40. PMID: 9498980.
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    294. Irish J, Dasgupta R, Freeman J, Gullane P, Gentili F, Brown D, Neligan P, O'Sullivan B. Outcome and analysis of the surgical management of esthesioneuroblastoma. J Otolaryngol. 1997 Feb; 26(1):1-7. PMID: 9055166.
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    298. Bouwes Bavinck JN, Hardie DR, Green A, Cutmore S, MacNaught A, O'Sullivan B, Siskind V, Van Der Woude FJ, Hardie IR. The risk of skin cancer in renal transplant recipients in Queensland, Australia. A follow-up study. Transplantation. 1996 Mar 15; 61(5):715-21. PMID: 8607173.
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    304. VanderMeer TJ, Menconi MJ, O'Sullivan BP, Larkin VA, Wang H, Sofia M, Fink MP. Acute lung injury in endotoxemic pigs: role of leukotriene B4. J Appl Physiol (1985). 1995 Mar; 78(3):1121-31. PMID: 7775306.
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    306. Nimkin K, Kleinman PK, Zwerdling RG, Spevak MR, O'Sullivan BP. Localized pneumothorax with lobar collapse and diffuse obstructive airway disease. Pediatr Radiol. 1995; 25(6):449-51. PMID: 7491198.
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    307. Wollert PS, Menconi MJ, Wang H, O'Sullivan BP, Larkin V, Allen RC, Fink MP. Prior exposure to endotoxin exacerbates lipopolysaccharide-induced hypoxemia and alveolitis in anesthetized swine. Shock. 1994 Nov; 2(5):362-9. PMID: 7743363.
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    308. O'Sullivan BP, Spaulding R. The use of aerosolized pentamidine for prophylaxis of Pneumocystis carinii pneumonia in children with leukemia. Pediatr Pulmonol. 1994 Oct; 18(4):228-31. PMID: 7838621.
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    316. O'Sullivan BP, Nimkin K, Gang DL. A fifteen-year-old boy with eosinophilia and pulmonary infiltrates. J Pediatr. 1993 Oct; 123(4):660-6. PMID: 8410525.
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    320. Keane TJ, Cummings BJ, O'Sullivan B, Payne D, Rawlinson E, MacKenzie R, Danjoux C, Hodson I. A randomized trial of radiation therapy compared to split course radiation therapy combined with mitomycin C and 5 fluorouracil as initial treatment for advanced laryngeal and hypopharyngeal squamous carcinoma. Int J Radiat Oncol Biol Phys. 1993 Mar 15; 25(4):613-8. PMID: 8454478.
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    321. O'Sullivan BP, Mong S, Votta B, Schidlow DV. Reduction of eicosanoid production by essential fatty acid depletion does not attenuate the inflammatory response induced by Pseudomonas aeruginosa pneumonia in rat lung. Prostaglandins Leukot Essent Fatty Acids. 1992 Jul; 46(3):203-10. PMID: 1324504.
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    322. Alpert BE, O'Sullivan BP, Panitch HB. Nonbronchoscopic approach to bronchoalveolar lavage in children with artificial airways. Pediatr Pulmonol. 1992 May; 13(1):38-41. PMID: 1589310.
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    323. Nielsen OS, Cummings B, O'Sullivan B, Catton C, Bell RS, Fornasier VL. Preoperative and postoperative irradiation of soft tissue sarcomas: effect of radiation field size. Int J Radiat Oncol Biol Phys. 1991 Nov; 21(6):1595-9. PMID: 1938569.
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    324. Wong CS, Cummings BJ, Keane TJ, Dobrowsky W, O'Sullivan B, Catton CN. Combined radiation therapy, mitomycin C, and 5-fluorouracil for locally recurrent rectal carcinoma: results of a pilot study. Int J Radiat Oncol Biol Phys. 1991 Oct; 21(5):1291-6. PMID: 1938526.
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    325. Cummings BJ, Keane TJ, O'Sullivan B, Wong CS, Catton CN. Epidermoid anal cancer: treatment by radiation alone or by radiation and 5-fluorouracil with and without mitomycin C. Int J Radiat Oncol Biol Phys. 1991 Oct; 21(5):1115-25. PMID: 1938508.
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    326. Wong CS, Cummings BJ, Keane TJ, O'Sullivan B, Catton CN. Results of external beam irradiation for rectal carcinomas locally recurrent after local excision or electrocoagulation. Radiother Oncol. 1991 Oct; 22(2):145-8. PMID: 1957006.
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    327. Catton CN, Cummings BJ, Fornasier V, O'Sullivan B, Quirt I, Warr D. Adult paratesticular sarcomas: a review of 21 cases. J Urol. 1991 Aug; 146(2):342-5. PMID: 1906946.
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    328. Moore MJ, O'Sullivan B, Tannock IF. Are treatment strategies of urologic oncologists influenced by the opinions of their colleagues? Br J Cancer. 1990 Dec; 62(6):988-91. PMID: 2257231; PMCID: PMC1971580.
    329. O'Sullivan BP, Mong S. Binding of radiolabeled high affinity antagonist to leukotriene D4 receptor in guinea pig lung membranes: interconversion of agonist-receptor binding affinity states. Mol Pharmacol. 1989 Jun; 35(6):795-802. PMID: 2543913.
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    330. Bell RS, O'Sullivan B, Liu FF, Powell J, Langer F, Fornasier VL, Cummings B, Miceli PN, Hawkins N, Quirt I, et al. The surgical margin in soft-tissue sarcoma. J Bone Joint Surg Am. 1989 Mar; 71(3):370-5. PMID: 2925710.
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    331. Feigen M, Cummings B, Hawkins N, Keane T, O'Sullivan B, Wong S. Low dose postoperative adjuvant radiation therapy for rectal cancer is ineffective. Radiother Oncol. 1988 Nov; 13(3):181-6. PMID: 3222463.
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    332. O'Sullivan B. Limb-sparing management in extremity soft-tissue sarcomas in the adult: the radiation oncologist's viewpoint. Can J Surg. 1988 Nov; 31(6):397-403. PMID: 3052764.
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    333. Moore MJ, O'Sullivan B, Tannock IF. How expert physicians would wish to be treated if they had genitourinary cancer. J Clin Oncol. 1988 Nov; 6(11):1736-45. PMID: 3054004.
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    334. O'Sullivan BP. Carbon monoxide poisoning in an infant exposed to a kerosene heater. J Pediatr. 1983 Aug; 103(2):249-51. PMID: 6875719.
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