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Last Name
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Dennis A Tighe MD

TitleProfessor
InstitutionUniversity of Massachusetts Medical School
DepartmentMedicine
AddressUniversity of Massachusetts Medical School
55 Lake Avenue North
Worcester MA 01655
Phone508-334-7500
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    Other Positions
    InstitutionUMMS - School of Medicine
    DepartmentMedicine
    DivisionCardiovascular Medicine


    Collapse Biography 
    Collapse education and training
    University of Pennsylvania, Philadelphia, PA, United StatesBABiology
    University of Massachusetts Medical School, Worcester, MA, United StatesMD

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Ahmed M, Sardana M, Rasla S, Escobar J, Bote J, Iskandar A, Tran KV, Tighe DA, Fitzgibbons TP, Aurigemma GP. Comparative left ventricular mechanical deformation in acute apical variant stress cardiomyopathy and acute anterior myocardial infarction utilizing 2-dimensional longitudinal strain imaging. Echocardiography. 2020 May 21. PMID: 32437588.
      View in: PubMed
    2. Gentile BA, Tighe DA. Situs Inversus Totalis. N Engl J Med. 2019 Jun 13; 380(24):e45. PMID: 31189040.
      View in: PubMed
    3. Velagapudi VM, Tighe DA. Letter on "Left ventricular systolic function evaluated by strain echocardiography and relationship with mortality in patients with severe sepsis or septic shock: a systematic review and meta-analysis". Crit Care. 2019 Feb 08; 23(1):38. PMID: 30736846.
      View in: PubMed
    4. Velagapudi VM, Pidikiti R, Tighe DA. Is Left Ventricular Global Longitudinal Strain by Two-Dimensional Speckle Tracking Echocardiography in Sepsis Cardiomyopathy Ready for Prime Time Use in the ICU? Healthcare (Basel). 2019 Jan 03; 7(1). PMID: 30609787.
      View in: PubMed
    5. Iskandar A, Mowakeaa S, Sardana M, Fitzgibbons TP, Tighe DA, Parker MW, Kakouros N, McManus D, Aurigemma GP. The presbycardia phenotype: Cardiac remodeling and valvular degeneration in nonagenarians. Echocardiography. 2018 Nov 15. PMID: 30431175.
      View in: PubMed
    6. Velagapudi VM, Tighe D. Data Abstraction Error in Systematic Review of Global Longitudinal Strain Using Speckle-Tracking Echocardiography as a Mortality Predictor in Sepsis. J Intensive Care Med. 2018 Sep 11; 885066618799638. PMID: 30205731.
      View in: PubMed
    7. Khan UA, Aurigemma GP, Tighe DA. Vector velocity imaging echocardiography to study the effects of submassive pulmonary embolism on the right atrium. Echocardiography. 2018 Feb; 35(2):204-210. PMID: 29178134.
      View in: PubMed
    8. Tighe D, Sassoon I, McGurk M. Validating a benchmarking tool for audit of early outcomes after operations for head and neck cancer. Ann R Coll Surg Engl. 2017 Apr; 99(4):299-306. PMID: 27917662.
      View in: PubMed
    9. Tighe DA, Aurigemma GP. C'est LAVi: What Left Atrial Dilatation Tells Us About Diastolic Function in Aortic Stenosis. Circ Cardiovasc Imaging. 2016 Oct; 9(10). PMID: 27894073.
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    10. Velagapudi V, O'Horo JC, Vellanki A, Baker SP, Pidikiti R, Stoff JS, Tighe DA. Computer-assisted image processing 12 lead ECG model to diagnose hyperkalemia. J Electrocardiol. 2017 Jan - Feb; 50(1):131-138. PMID: 27662777.
      View in: PubMed
    11. Shaikh AY, Suryadevara S, Tripathi A, Ahmed M, Kane JL, Escobar J, Cerny J, Nath R, McManus DD, Shih J, McGuiness ME, Tighe DA, Meyer TE, Ramanathan M, Aurigemma GP. Mitoxantrone-Induced Cardiotoxicity in Acute Myeloid Leukemia-A Velocity Vector Imaging Analysis. Echocardiography. 2016 Aug; 33(8):1166-77. PMID: 27109429.
      View in: PubMed
    12. Medeiros K, O'Connor M, Baicu CF, Fitzgibbons T, Shaw P, Tighe DA, Zile MR, Aurigemma GP. Response to letters regarding article, "systolic and diastolic mechanics in stress cardiomyopathy". Circulation. 2015 Mar 10; 131(10):e372. PMID: 25753351.
      View in: PubMed
    13. Fahed J, Floyd KC, Tighe DA. Sudden cardiac death in postmyocardial-infarction patients. Panminerva Med. 2015 Jun; 57(2):71-86. PMID: 25669163.
      View in: PubMed
    14. Zacharias M, Chandok D, Tighe D. A late presentation of an anomalous left coronary artery originating from the pulmonary artery (ALCAPA): A case study and review of the literature. J Cardiol Cases. 2015 Feb; 11(2):56-59. PMID: 30534259.
      View in: PubMed
    15. Haldar S, Mandalia U, Skelton E, Chow V, Turner SS, Ramesar K, Tighe D, Williams M, Howlett D. Diagnostic investigation of parotid neoplasms: a 16-year experience of freehand fine needle aspiration cytology and ultrasound-guided core needle biopsy. Int J Oral Maxillofac Surg. 2015 Feb; 44(2):151-7. PMID: 25457828.
      View in: PubMed
    16. Medeiros K, O'Connor MJ, Baicu CF, Fitzgibbons TP, Shaw P, Tighe DA, Zile MR, Aurigemma GP. Systolic and diastolic mechanics in stress cardiomyopathy. Circulation. 2014 Apr 22; 129(16):1659-67. PMID: 24503950.
      View in: PubMed
    17. Zacharias M, Tighe DA, Aurigemma G. A Case of LV "Pseudo" Pseudodyskinesis. Echocardiography. 2013 Oct; 30(9):1118-20. PMID: 23937550.
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    18. Shaikh AY, Meyer TE, Robotis DA, Aurigemma GP, Tighe DA. Systolic pulmonary and hepatic vein flow reversal due to pacemaker-induced retrograde ventriculoatrial conduction. Echocardiography. 2013 Mar; 30(3):E61-3. PMID: 23305160.
      View in: PubMed
    19. Khan UA, de Simone G, Hill J, Tighe DA, Aurigemma GP. Depressed atrial function in diastolic dysfunction: a speckle tracking imaging study. Echocardiography. 2013 Mar; 30(3):309-16. PMID: 23237327.
      View in: PubMed
    20. Shaikh AY, Maan A, Khan UA, Aurigemma GP, Hill JC, Kane JL, Tighe DA, Mick E, McManus DD. Speckle echocardiographic left atrial strain and stiffness index as predictors of maintenance of sinus rhythm after cardioversion for atrial fibrillation: a prospective study. Cardiovasc Ultrasound. 2012 Dec 03; 10:48. PMID: 23199055.
      View in: PubMed
    21. Shaikh AY, Maan A, Heist EK, Tighe DA, Aurigemma GP, McManus DD. Management strategies in atrial fibrillation in patients with heart failure. Cardiol Rev. 2012 Nov-Dec; 20(6):288-96. PMID: 22581123.
      View in: PubMed
    22. Ofman P, Cook JR, Navaravong L, Levine RA, Peralta A, Gaziano JM, Djousse L, Curillova Z, Hoffmeister P, Smoot K, Jiang L, Tighe DA, Stoenescu ML. T-wave inversion and diastolic dysfunction in patients with electrocardiographic left ventricular hypertrophy. J Electrocardiol. 2012 Nov-Dec; 45(6):764-9. PMID: 22819483.
      View in: PubMed
    23. Jagannath AD, Johri AM, Liberthson R, Larobina M, Passeri J, Tighe D, Agnihotri AK. Quadricuspid aortic valve: a report of 12 cases and a review of the literature. Echocardiography. 2011 Oct; 28(9):1035-40. PMID: 21854429.
      View in: PubMed
    24. Madias C, Fitzgibbons TP, Alsheikh-Ali AA, Bouchard JL, Kalsmith B, Garlitski AC, Tighe DA, Estes NA, Aurigemma GP, Link MS. Acquired long QT syndrome from stress cardiomyopathy is associated with ventricular arrhythmias and torsades de pointes. Heart Rhythm. 2011 Apr; 8(4):555-61. PMID: 21146632.
      View in: PubMed
    25. Santolucito PA, Tighe DA, McManus DD, Yarzebski J, Lessard D, Gore JM, Goldberg RJ. Management and outcomes of renal disease and acute myocardial infarction. Am J Med. 2010 Sep; 123(9):847-55. PMID: 20800154.
      View in: PubMed
    26. Tighe DA, Aurigemma GP. Right-to-left shunts and saline contrast echocardiography. Chest. 2010 Aug; 138(2):246-8. PMID: 20682525.
      View in: PubMed
    27. Shaikh AY, Tighe DA. Should physicians stop prescribing nonsteroidal anti-inflammatory drugs for postoperative pericardial effusion? Ann Intern Med. 2010 Jun 15; 152(12):826-7; author reply 827. PMID: 20547916.
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    28. Herman M, Donovan J, Tran M, McKenna B, Gore JM, Goldberg RJ, Tighe DA. Use of beta-blockers and effects on heart rate and blood pressure post-acute coronary syndromes: are we on target? Am Heart J. 2009 Sep; 158(3):378-85. PMID: 19699860.
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    29. Joffe SW, Ferrara J, Chalian A, Tighe DA, Aurigemma GP, Goldberg RJ. Are ejection fraction measurements by echocardiography and left ventriculography equivalent? Am Heart J. 2009 Sep; 158(3):496-502. PMID: 19699876.
      View in: PubMed
    30. Joffe SW, Chalian A, Tighe DA, Aurigemma GP, Yarzebski J, Gore JM, Lessard D, Goldberg RJ. Trends in the use of echocardiography and left ventriculography to assess left ventricular ejection fraction in patients hospitalized with acute myocardial infarction. Am Heart J. 2009 Aug; 158(2):185-92. PMID: 19619693.
      View in: PubMed
    31. Narayanan A, Aurigemma GP, Chinali M, Hill JC, Meyer TE, Tighe DA. Cardiac mechanics in mild hypertensive heart disease: a speckle-strain imaging study. Circ Cardiovasc Imaging. 2009 Sep; 2(5):382-90. PMID: 19808626.
      View in: PubMed
    32. Fitzgibbons TP, Madias C, Seth A, Bouchard JL, Kuvin JT, Patel AR, Pandian NG, Meyer TE, Aurigemma GP, Tighe DA. Prevalence and clinical characteristics of right ventricular dysfunction in transient stress cardiomyopathy. Am J Cardiol. 2009 Jul 1; 104(1):133-6. PMID: 19576334.
      View in: PubMed
    33. Bouchard JL, Aurigemma GP, Hill JC, Ennis CA, Tighe DA. Usefulness of the pulmonary arterial systolic pressure to predict pulmonary arterial wedge pressure in patients with normal left ventricular systolic function. Am J Cardiol. 2008 Jun 1; 101(11):1673-6. PMID: 18489950.
      View in: PubMed
    34. Santolucito PA, Tighe DA, Lessard D, Ismailov RM, Gore JM, Yarzebski J, Goldberg RJ. Changing trends in the evaluation of ejection fraction in patients hospitalized with acute myocardial infarction: the Worcester Heart Attack Study. Am Heart J. 2008 Mar; 155(3):485-93. PMID: 18294481.
      View in: PubMed
    35. Tighe DA, Rosetti M, Vinch CS, Chandok D, Muldoon D, Wiggin B, Dahlberg ST, Aurigemma GP. Influence of image quality on the accuracy of real time three-dimensional echocardiography to measure left ventricular volumes in unselected patients: a comparison with gated-SPECT imaging. Echocardiography. 2007 Nov; 24(10):1073-80. PMID: 18001361.
      View in: PubMed
    36. Duffis EJ, Jones D, Tighe D, Moonis M. Neurological complications of coronary angiographic procedures. Expert Rev Cardiovasc Ther. 2007 Nov; 5(6):1113-21. PMID: 18035927.
      View in: PubMed
    37. Hurlburt HM, Aurigemma GP, Hill JC, Narayanan A, Gaasch WH, Vinch CS, Meyer TE, Tighe DA. Direct ultrasound measurement of longitudinal, circumferential, and radial strain using 2-dimensional strain imaging in normal adults. Echocardiography. 2007 Aug; 24(7):723-31. PMID: 17651101.
      View in: PubMed
    38. Bouchard JL, Aurigemma GP, Goldberg RJ, Fournier JB, Vinch CS, Hill JC, Ennis CA, Tighe DA, Meyer TE. Heart failure in the "oldest old": clinical and echocardiographic insights. Am J Geriatr Cardiol. 2007 Jul-Aug; 16(4):236-42. PMID: 17617750.
      View in: PubMed
    39. Rosetti M, Tighe DA, Chandok D, Gammie JS, Griffith BP, Folland ED. An unusual cause of pulmonary vein stenosis: a case report and review of the literature. Echocardiography. 2006 Sep; 23(8):685-8. PMID: 16970720.
      View in: PubMed
    40. Aurigemma GP, Tighe DA. Echocardiography and reversible left ventricular dysfunction. Am J Med. 2006 Jan; 119(1):18-21. PMID: 16431177.
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    41. Tighe DA, Ockene IS, Reed G, Nicolosi R. Calculated low density lipoprotein cholesterol levels frequently underestimate directly measured low density lipoprotein cholesterol determinations in patients with serum triglyceride levels < or =4.52 mmol/l: an analysis comparing the LipiDirect magnetic LDL assay with the Friedewald calculation. Clin Chim Acta. 2006 Mar; 365(1-2):236-42. PMID: 16259972.
      View in: PubMed
    42. Vinch CS, Aurigemma GP, Simon HU, Hill JC, Tighe DA, Meyer TE. Analysis of left ventricular systolic function using midwall mechanics in patients >60 years of age with hypertensive heart disease and heart failure. Am J Cardiol. 2005 Nov 1; 96(9):1299-303. PMID: 16253602.
      View in: PubMed
    43. Aghassi P, Aurigemma GP, Folland ED, Tighe DA. Catheterization-Doppler discrepancies in nonsimultaneous evaluations of aortic stenosis. Echocardiography. 2005 May; 22(5):367-73. PMID: 15901286.
      View in: PubMed
    44. Vinch CS, Hill JC, Logsetty G, Tighe DA, Meyer TE, Aurigemma GP. Paradoxical changes in brain natriuretic peptide levels and loading conditions after intravenous conscious sedation. J Am Soc Echocardiogr. 2004 Nov; 17(11):1191-6. PMID: 15502796.
      View in: PubMed
    45. Tighe DA. Electrocardiology teacher analysis and review: ventriculophasic sinus arrhythmia. Am J Geriatr Cardiol. 2004 Nov-Dec; 13(6):336. PMID: 15538075.
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    46. Vinch CS, Rashkin J, Logsetty G, Tighe DA, Hill JC, Meyer TE, Rosenthal LS, Aurigemma GP. Brain natriuretic peptide levels fall rapidly after cardioversion of atrial fibrillation to sinus rhythm. Cardiology. 2004; 102(4):188-93. PMID: 15452391.
      View in: PubMed
    47. Feingold AD, Tighe DA, Aurigemma GP, Hill JC, Vinch CS. The utility of newly derived Doppler echocardiographic variables in the diagnosis and management of patients with heart failure. Curr Cardiol Rep. 2004 May; 6(3):217-24. PMID: 15075059.
      View in: PubMed
    48. Studley J, Tighe DA, Joelson JM, Flack JE. The hemodynamic signs of constrictive pericarditis can be mimicked by tricuspid regurgitation. Cardiol Rev. 2003 Nov-Dec; 11(6):320-6. PMID: 14580301.
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    49. Vinch CS, Aurigemma GP, Hill JC, Gaasch WH, Volturo G, Tighe DA, Meyer TE. Usefulness of clinical variables, echocardiography, and levels of brain natriuretic peptide and norepinephrine to distinguish systolic and diastolic causes of acute heart failure. Am J Cardiol. 2003 May 1; 91(9):1140-3. PMID: 12714167.
      View in: PubMed
    50. Tighe DA, Vinch CS, Hill JC, Meyer TE, Goldberg RJ, Aurigemma GP. Influence of age on assessment of diastolic function by Doppler tissue imaging. Am J Cardiol. 2003 Jan 15; 91(2):254-7. PMID: 12521648.
      View in: PubMed
    51. Seth PS, Aurigemma GP, Krasnow JM, Tighe DA, Untereker WJ, Meyer TE. A syndrome of transient left ventricular apical wall motion abnormality in the absence of coronary disease: a perspective from the United States. Cardiology. 2003; 100(2):61-6. PMID: 14557691.
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    52. Botkin NF, Aurigemma GP, Meyer TE, Tighe DA. Periprosthetic aortic valve ring abscess. Echocardiography. 2002 Oct; 19(7 Pt 1):569-70. PMID: 12376009.
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    53. Bakris N, Tighe DA, Rousou JA, Hiser WL, Flack JE, Engelman RM. Nonobstructive membranes of the left atrial appendage cavity: report of three cases. J Am Soc Echocardiogr. 2002 Mar; 15(3):267-70. PMID: 11875392.
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    54. Tighe DA, Paul JJ, Huhta JC. Superior vena caval syndrome: color flow Doppler detection of collateral venous channels. J Am Soc Echocardiogr. 2000 Aug; 13(8):780-4. PMID: 10936823.
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    55. Tighe DA, Anene CA, Rousou JA, King AK, Engelman RM. Primary cardiac lymphoma. Echocardiography. 2000 May; 17(4):345-7. PMID: 10979005.
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    56. Rousou JA, Tighe DA, Garb JL, Krasner H, Engelman RM, Flack JE, Deaton DW. Risk of dysphagia after transesophageal echocardiography during cardiac operations. Ann Thorac Surg. 2000 Feb; 69(2):486-9; discussion 489-90. PMID: 10735685.
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    57. Krasner H, Tighe D. A complex echocardiographic diagnosis. J Cardiothorac Vasc Anesth. 1999 Oct; 13(5):635-7. PMID: 10527239.
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    58. Tighe DA, Paul JJ, Pohl CA, Cook JR, Huhta JC. Automatic Border Detection for Assessment of Left Ventricular Diastolic Function Among Normal Neonates: Comparison with Doppler Echocardiography. Echocardiography. 1998 Aug; 15(6):545-552. PMID: 11175078.
      View in: PubMed
    59. Tighe DA, Thomas NV, Hafer JG, Rousou JA, Engelman RM, Anene CA, Fernandez E, Rifkin RD. Diagnosis of Partial Anomalous Pulmonary Venous Connection with Intact Interatrial Septum by Echocardiography. Echocardiography. 1998 May; 15(4):405-408. PMID: 11175057.
      View in: PubMed
    60. Rousou JA, Tighe DA, Rifkin RD, Engelman RM, Flack JE, Deaton DW, Anene CA, Fernandes EA. Echocardiography allows safer venous cannulation during excision of large right atrial masses. Ann Thorac Surg. 1998 Feb; 65(2):403-6. PMID: 9485236.
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    61. Mangion JR, Popowski BE, Joelson JM, Tighe DA. Severe Aortic Coarctation in an Adult Without Left Ventricular Hypertrophy Nor Overt Collateral Channels. Echocardiography. 1997 Jul; 14(4):393-398. PMID: 11174972.
      View in: PubMed
    62. Tighe DA, Paul JJ, Maniet AR, Flack JE, Mannion JD, Rifkin RD, Raichlen JS. Survival in Infarct Related Intramyocardial Dissection Importance of Early Echocardiography and Prompt Surgery. Echocardiography. 1997 Jul; 14(4):403-408. PMID: 11174974.
      View in: PubMed
    63. Paul JJ, Desai H, Baumgart S, Wolfson P, Russo P, Tighe DA. Aortic dissection in a neonate associated with arterial cannulation for extracorporeal life support. ASAIO J. 1997 Jan-Feb; 43(1):92-4. PMID: 9116361.
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    64. Engelman RM, Engelman DT, Rousou JA, Flack JE, Deaton DW, Tighe DA, Rifkin RD, Gregory CA. The influence of myocardial temperature on stunning following coronary revascularization. Ann N Y Acad Sci. 1996 Sep 30; 793:319-27. PMID: 8906175.
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    65. Rifkin RD, Harper KA, Tighe DA, Elmansoury N, D'Amours J. Echocardiographic Findings in Rupture of Long False Tendons: Report of Two Cases. Echocardiography. 1996 Sep; 13(5):499-502. PMID: 11442960.
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    66. Tighe DA, Tejada LA, Kirchhoffer JB, Gilmette P, Rifkin RD, Estes NA. Pacemaker lead infection: detection by multiplane transesophageal echocardiography. Am Heart J. 1996 Mar; 131(3):616-8. PMID: 8604651.
      View in: PubMed
    67. Tighe DA, Rousou JA, Kenia S, Kulshrestha P. Transesophageal echocardiography in the management of mitral valve myxoma. Am Heart J. 1995 Sep; 130(3 Pt 1):627-9. PMID: 7661089.
      View in: PubMed
    68. Rifkin RD, Harper K, Tighe D. Comparison of proximal isovelocity surface area method with pressure half-time and planimetry in evaluation of mitral stenosis. J Am Coll Cardiol. 1995 Aug; 26(2):458-65. PMID: 7608451.
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    69. Marshall ES, Raichlen JS, Kim SM, Intenzo CM, Sawyer DT, Brody EA, Tighe DA, Park CH. Prognostic significance of ST-segment depression during adenosine perfusion imaging. Am Heart J. 1995 Jul; 130(1):58-66. PMID: 7611124.
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    70. Mangion JR, Tighe DA. Aortic valvular disease in adults. A potentially lethal clinical problem. Postgrad Med. 1995 Jul; 98(1):127-35, 140. PMID: 7603942.
      View in: PubMed
    71. Mangion JR, Tighe DA. Aortic valvular disease in adults. Postgrad Med. 1995 Jul; 98(1):127-140. PMID: 29224474.
      View in: PubMed
    72. Kulshrestha P, Rousou JA, Tighe DA. Mitral valve myxoma: a case report and brief review of the literature. J Heart Valve Dis. 1995 Mar; 4(2):196-8. PMID: 8556183.
      View in: PubMed
    73. Tighe DA, Hutchinson HG, Park CH, Chung EK, Fischman DL, Raichlen JS. False-positive reversible perfusion defect during dobutamine-thallium imaging in left bundle branch block. J Nucl Med. 1994 Dec; 35(12):1989-91. PMID: 7989982.
      View in: PubMed
    74. Tighe DA, Chung EK, Park CH. Electric alternans associated with acute pulmonary embolism. Am Heart J. 1994 Jul; 128(1):188-90. PMID: 8017275.
      View in: PubMed
    75. Marshall ES, Raichlen JS, Tighe DA, Paul JJ, Breuninger KM, Chung EK. ST-segment depression during adenosine infusion as a predictor of myocardial ischemia. Am Heart J. 1994 Feb; 127(2):305-11. PMID: 8296697.
      View in: PubMed
    76. Tighe D, Brest AN. Congestive heart failure in the elderly. Cardiovasc Clin. 1992; 22(2):127-38. PMID: 1586914.
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    77. Haywood GA, Tighe D, Moss R, al-Saady N, Foshola TO, Riley SP, Pearson I, Webb A, McKenna WJ, Bennett ED. Goal directed therapy with dobutamine in a porcine model of septic shock: effects on systemic and renal oxygen transport. Postgrad Med J. 1991; 67 Suppl 1:S36-9; discussion S40-1. PMID: 1924077.
      View in: PubMed
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