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Last Name

Kristina M Deligiannidis MD

TitleAdjunct Associate Professor
InstitutionUniversity of Massachusetts Medical School
AddressZucker Hillside Hospital- Kaufman Bldg
75-59 263rd Street, Suite 103
Glen Oaks NY 11004
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    InstitutionUMMS - School of Medicine

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    University of Massachusetts Amherst, Amherst, MA, United StatesBSBiology/ Psychology
    University of Massachusetts Medical School, Worcester, MA, United StatesMDMedicine
    Collapse awards and honors
    1996Summer Intramural Research Training Award;Developmental Endocrinology/Genetics/Neuroendocrinology, NIH/NICHD
    1997Commonwealth Scholar; Univ. of Massachusetts at Amherst
    1998 - 2000Predoctoral Intramural Research Training Award;Developmental Endocrinology/Genetics/Neuroendocrine, NIH/NICHD
    2003Medical Student Clinical Research Electives Program:Pediatrics & Developmental Neuropsychiatry , NIH/NICHD
    2003 - 2004Charles J. Hoff Scholar; UMass Medical School
    2004T. Byram Karasu Award in Psychotherapy for Medical Students
    2007 - 2008ASCP/NIMH Clinical Trials in Psychopharmacology Award
    2008 - 2009APA/APIRE Junior Investigator Awards
    2009Paul F. Briscoli Award for Resident-Faculty Academic Collaboration; UMass Medical School
    2009Resident Educator Award; UMass Medical School
    2009Resident Elective Program in Clinical Research; Experimental Therapeutics/Pathophysiology Branch, NIH/NIMH
    2009Resident Elective Program in Clinical Research; Behavioral Endocrinology Branch, NIH/NIMH
    2009ASCP/NCDEU/NIMH New Investigator Award
    2010Worcester Foundation for Biomedical Research Grant
    2011Society for Biological Psychiatry (SOBP) Travel Scholarship Award
    2011Career Development Research Fellowship Award; UMass Medical Dept. Psychiatry
    2011Faculty Scholar Award; UMass Medical School
    2011 - 2013NIH/UMass Medical CTSA Pilot Project Program Grant, NIH/NCATS
    2012Faculty Teaching Award for Outstanding Resident Teaching; UMass Medical School Dept. Psychiatry
    2012 - 2014Career Development Institute (CDI) for Psychiatry Award (NIMH R25) Univ. Pittsburgh/Stanford Univ., NIH/NIMH
    2013 - 2018NIH/NIMH K23 Career Development Award, NIH/NIMH
    2013Early Career Achievement in Science and Health Award; UMass Medical School
    2013Best Doctors in America
    2013National Network of Depression Centers (NNDC) Annual Scientific Conference Travel Award
    2014ACNP (American College of Neuropsychopharmacology) Travel Award
    2014 - 2016NIH/NIMH Clinical Research Loan Repayment Program Award, NIH/NIMH
    2014NIH Early Career Reviewer, Center for Scientific Review, NIH/CSR
    2016SOBP George N Thompson Award for Distinguished Service, SOBP

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    Dr. Deligiannidis completed her undergraduate degrees and an Honors Scholars Research Program in Neuroscience and Behavior at the University of Massachusetts at Amherst.  As a recipient of NIH pre-doctoral Intramural Research Training Awards, she trained in molecular neuroendocrinology research at the NIH/National Institutes of Child Health and Human Development (NIH/NICHD). 

    Dr. Deligiannidis completed additional research training at the National Institute of Mental Health (NIMH) and NICHD during medical school and residency.  She received her medical degree from the University of Massachusetts Medical School and completed her psychiatry residency and chief residency in psychopharmacology research at UMass Medical School (UMMS)/UMass Memorial Health Care (UMMHC).  Dr. Deligiannidis joined faculty at UMMS in October 2009,  is currently an Associate Professor of Psychiatry and is Board Certified by the American Board of Psychiatry and Neurology.

    Dr. Deligiannidis is the Director of the Depression Specialty Clinic, a regional referral center at UMMHC that specializes in the evaluation and treatment of adult patients suffering from major depression, psychotic depression, treatment-resistant depression and bipolar depression.

    Dr. Deligiannidis also evaluates and treats women in the Women’s Mental Health Specialty Clinic at UMMHC.  She provides consultation and short-term treatment of women suffering from depression and anxiety during pregnancy or the post-partum period. Her expertise is focused on psychopharmacologic and complementary/alternative treatments for depression/anxiety during the perinatal period.

    Dr. Deligiannidis conducts translational research in the causes of perinatal depression.  She also conducts depression research on novel therapeutics.  Research areas of expertise include:

    • Psychoneuroendocrinology

    • Neuroimaging  (MRS, fMRI, fcMRI, DTI)

    • Neuroimaging and neuroendocrine biomarkers of depression in women during perinatal period

    • Gender differences in depression and treatment response

    • Psychopharmacology clinical trials/novel therapeutics

    • Complementary and alternative/integrative treatments

    Dr. Deligiannidis's research efforts have been nationally recognized.  She is the recipient of: a 2014 ACNP (American College of Neuropsychopharmacology) Travel Award; 2013-2018 NIH K23 Career Development Award, 2014-2016 NIH LRP Award, 2012 Research Career Development Institute (CDI) for Psychiatry Award (University of Pittsburgh/Stanford University), 2011 UMass Medical School Center for Clinical & Translational Science (CTSA) Pilot Grant, a UMMS Faculty Scholar Award, a 2011 Society for Biological Psychiatry Travel Scholarship Award, a 2010 Worcester Foundation for Biomedical Research Grant; a 2009 NIMH/NCDEU New Investigator Award, APA/APIRE Junior Investigator Awards (2008, 2009) and American Society of Clinical Psychopharmacology/NIMH Clinical Trials in Psychopharmacology Awards (2007, 2008).  At UMass, she has received the Early Career Achievement Award in Science and Health (2013) and several teaching awards.

    Dr. Deligiannidis actively participates in national scientific committees and gives scientific presentations locally, regionally and nationally.  She is an appointed Young Investigator Member of the International Society of Psychoneuroendocrinology (ISPNE) and a member of the Society of Biological Psychiatry (SOBP) and the American Society of Clinical Psychopharmacology (ASCP). 

    She serves on the Board of Directors of ASCP and on the Advisory Board for Acta Psychiatrica Scandinavica, is Chair of the SOBP Education Committee and is an Early Career Reviewer at NIH/CSR.

    Collapse Rotation Projects

    University of Massachusetts Medical School Summer Research Program for Medical Students

    If interested, please contact Dr. Kristina Deligiannidis and read description below.

    University of Massachusetts Medical School Senior Scholars Project

    If interested, please contact Dr. Kristina Deligiannidis to discuss research project ideas.

    University of Massachusetts Medical School Volunteer Research Opportunity

    My research lab actively investigates biological markers (endocrine and brain imaging) which may predict which women are at risk or who are "protected" from developing perinatal depression or anxiety. 

    I have worked with and trained several undergraduate, graduate and medical students in these research studies.

    The student's role, once CITI trained, is hands on with research participants under supervision.  Students learn about informed consent and perform depression screening in pregnant women and conduct visits on labor/delivery;  learn how research interviews are conducted which assess not only psychiatric symptoms but obstetric information; evaluate participants longitudinally from late pregnancy to the postpartum; learn about neuroendocrine biomarkers and their significance towards understanding the pathophysiology of perinatal depression; attend neuroimaging sessions at UMass Medical School, obtain collaborative skills with principal investigator (PI) and research coordinator involved in the study, perform minimal research database entry to be shared with PI and research coordinator, etc.  He/she will be able to learn about clinical trial design, recruitment strategies, research ethics, IRB procedures, etc. as they pertain to the study.  There are numerous facets in which to be involved, and the student would have a desk adjacent to the research coordinators in our research suite where the PI's office is within the CPRT research group.  The student would attend all research group meetings so that he/she would have exposure to the other studies ongoing in the CPRT research group.  Direct supervision would be by the PI for the entire research fellowship program.

    If you are interested in learning more, please contact Dr. Kristina Deligiannidis.

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Schoretsanitis G, Westin AA, Deligiannidis KM, Spigset O, Paulzen M. Excretion of antipsychotics into the amniotic fluid, umbilical cord blood, and breast milk: A systematic critical review and combined analysis. Ther Drug Monit. 2019 Aug 16. PMID: 31425493.
      View in: PubMed
    2. Frieder A, Fersh M, Hainline R, Deligiannidis KM. Pharmacotherapy of Postpartum Depression: Current Approaches and Novel Drug Development. CNS Drugs. 2019 Feb 21. PMID: 30790145.
      View in: PubMed
    3. Duan C, Hare MM, Staring M, Deligiannidis KM. Examining the relationship between perinatal depression and neurodevelopment in infants and children through structural and functional neuroimaging research. Int Rev Psychiatry. 2019 Jan 31; 1-16. PMID: 30701993.
      View in: PubMed
    4. Deligiannidis KM, Fales CL, Kroll-Desrosiers AR, Shaffer SA, Villamarin V, Tan Y, Hall JE, Frederick BB, Sikoglu EM, Edden RA, Rothschild AJ, Moore CM. Resting-state functional connectivity, cortical GABA, and neuroactive steroids in peripartum and peripartum depressed women: a functional magnetic imaging and resonance study. Neuropsychopharmacology. 2018 Oct 17. PMID: 30327498.
      View in: PubMed
    5. Reza N, Deligiannidis KM, Eustis EH, Battle CL. Complementary Health Practices for Treating Perinatal Depression. Obstet Gynecol Clin North Am. 2018 Sep; 45(3):441-454. PMID: 30092920.
      View in: PubMed
    6. Meltzer-Brody S, Colquhoun H, Riesenberg R, Epperson CN, Deligiannidis KM, Rubinow DR, Li H, Sankoh AJ, Clemson C, Schacterle A, Jonas J, Kanes S. Brexanolone injection in post-partum depression: two multicentre, double-blind, randomised, placebo-controlled, phase 3 trials. Lancet. 2018 Aug 31. PMID: 30177236.
      View in: PubMed
    7. Buglione-Corbett R, Deligiannidis KM, Leung K, Zhang N, Lee M, Rosal MC, Moore Simas TA. Expression of inflammatory markers in women with perinatal depressive symptoms. Arch Womens Ment Health. 2018 Mar 30. PMID: 29603018.
      View in: PubMed
    8. Silver M, Moore CM, Villamarin V, Jaitly N, Hall JE, Rothschild AJ, Deligiannidis KM. White matter integrity in medication-free women with peripartum depression: a tract-based spatial statistics study. Neuropsychopharmacology. 2018 Jun; 43(7):1573-1580. PMID: 29453442.
      View in: PubMed
    9. Tinkelman A, Hill EA, Deligiannidis KM. Management of New Onset Psychosis in the Postpartum Period. J Clin Psychiatry. 2017 Nov/Dec; 78(9):1423-1424. PMID: 29125722.
      View in: PubMed
    10. Duan C, Cosgrove J, Deligiannidis KM. Understanding Peripartum Depression Through Neuroimaging: a Review of Structural and Functional Connectivity and Molecular Imaging Research. Curr Psychiatry Rep. 2017 Aug 19; 19(10):70. PMID: 28823105.
      View in: PubMed
    11. Flynn HA, Spino C, Guille C, Deligiannidis KM, Maki P, Jahnke J, Rosenblum KL, Epperson CN, Weiss SJ. A Collaborative, Network-Based Approach to Advance Women's Depression Research in the United States: Preliminary Findings. J Womens Health (Larchmt). 2018 01; 27(1):51-57. PMID: 28727948.
      View in: PubMed
    12. Kanes S, Colquhoun H, Gunduz-Bruce H, Raines S, Arnold R, Schacterle A, Doherty J, Epperson CN, Deligiannidis KM, Riesenberg R, Hoffmann E, Rubinow D, Jonas J, Paul S, Meltzer-Brody S. Brexanolone (SAGE-547 injection) in post-partum depression: a randomised controlled trial. Lancet. 2017 Jun 12. PMID: 28619476.
      View in: PubMed
    13. Putnam KT, Wilcox M, Robertson-Blackmore E, Sharkey K, Bergink V, Munk-Olsen T, Deligiannidis KM, Payne J, Altemus M, Newport J, Apter G, Devouche E, Viktorin A, Magnusson P, Penninx B, Buist A, Bilszta J, O'Hara M, Stuart S, Brock R, Roza S, Tiemeier H, Guille C, Epperson CN, Kim D, Schmidt P, Martinez P, Di Florio A, Wisner KL, Stowe Z, Jones I, Sullivan PF, Rubinow D, Wildenhaus K, Meltzer-Brody S. Clinical phenotypes of perinatal depression and time of symptom onset: analysis of data from an international consortium. Lancet Psychiatry. 2017 May 03. PMID: 28476427.
      View in: PubMed
    14. Kroll-Desrosiers AR, Nephew BC, Babb JA, Guilarte-Walker Y, Moore Simas TA, Deligiannidis KM. Association of peripartum synthetic oxytocin administration and depressive and anxiety disorders within the first postpartum year. Depress Anxiety. 2017 Feb; 34(2):137-146. PMID: 28133901.
      View in: PubMed
    15. Di Florio A, Putnam K, Altemus M, Apter G, Bergink V, Bilszta J, Brock R, Buist A, Deligiannidis KM, Devouche E, Epperson CN, Guille C, Kim D, Lichtenstein P, Magnusson PK, Martinez P, Munk-Olsen T, Newport J, Payne J, Penninx BW, O'Hara M, Robertson-Blackmore E, Roza SJ, Sharkey KM, Stuart S, Tiemeier H, Viktorin A, Schmidt PJ, Sullivan PF, Stowe ZN, Wisner KL, Jones I, Rubinow DR, Meltzer-Brody S. The impact of education, country, race and ethnicity on the self-report of postpartum depression using the Edinburgh Postnatal Depression Scale. Psychol Med. 2017 Apr; 47(5):787-799. PMID: 27866476.
      View in: PubMed
    16. Jun-O'Connell AH, Butala A, Morales IB, Henninger N, Deligiannidis KM, Byatt N, Ionete C. The Prevalence of Bipolar Disorders and Association With Quality of Life in a Cohort of Patients With Multiple Sclerosis. J Neuropsychiatry Clin Neurosci. 2016 Aug 19; appineuropsych15120403. PMID: 27539374.
      View in: PubMed
    17. Deligiannidis KM, Kroll-Desrosiers AR, Mo S, Nguyen HP, Svenson A, Jaitly N, Hall JE, Barton BA, Rothschild AJ, Shaffer SA. Peripartum neuroactive steroid and ?-aminobutyric acid profiles in women at-risk for postpartum depression. Psychoneuroendocrinology. 2016 Aug; 70:98-107. PMID: 27209438.
      View in: PubMed
    18. Weiss SJ, Muzik M, Deligiannidis KM, Ammerman RT, Guille C, Flynn HA. J Depress Anxiety. Gender differences in suicide risk factors among individuals with mood disorders. 2016; 218(5).
    19. Deligiannidis KM, Kroll-Desrosiers AR, Svenson A, Jaitly N, Barton BA, Hall JE, Rothschild AJ. Cortisol response to the Trier Social Stress Test in pregnant women at risk for postpartum depression. Arch Womens Ment Health. 2016 Oct; 19(5):789-97. PMID: 26951216.
      View in: PubMed
    20. Deligiannidis KM. The physician-scientist workforce in the United States. Acta Psychiatr Scand. 2015 Oct; 132(4):317-8. PMID: 25950491.
      View in: PubMed
    21. Heterogeneity of postpartum depression: a latent class analysis. Lancet Psychiatry. 2015 Jan; 2(1):59-67. PMID: 26359613.
      View in: PubMed
    22. Østergaard SD, Fava M, Rothschild AJ, Deligiannidis KM. The implications of the National Institute of Mental Health Research Domain Criteria for researchers and clinicians. Acta Psychiatr Scand. 2014 Dec; 130(6):409-14. PMID: 25201294.
      View in: PubMed
    23. Babb JA, Deligiannidis KM, Murgatroyd CA, Nephew BC. Peripartum depression and anxiety as an integrative cross domain target for psychiatric preventative measures. Behav Brain Res. 2015 Jan 1; 276:32-44. PMID: 24709228.
      View in: PubMed
    24. Deligiannidis KM, Byatt N, Freeman MP. Pharmacotherapy for mood disorders in pregnancy: a review of pharmacokinetic changes and clinical recommendations for therapeutic drug monitoring. J Clin Psychopharmacol. 2014 Apr; 34(2):244-55. PMID: 24525634.
      View in: PubMed
    25. Deligiannidis KM, Rothschild AJ, Barton BA, Kroll-Desrosiers AR, Meyers BS, Flint AJ, Whyte EM, Mulsant BH. A gender analysis of the study of pharmacotherapy of psychotic depression (STOP-PD): gender and age as predictors of response and treatment-associated changes in body mass index and metabolic measures. J Clin Psychiatry. 2013 Oct; 74(10):1003-9. PMID: 24229753.
      View in: PubMed
    26. Smith EG, Deligiannidis KM, Ulbricht CM, Landolin CS, Patel JK, Rothschild AJ. Antidepressant augmentation using the N-methyl-D-aspartate antagonist memantine: a randomized, double-blind, placebo-controlled trial. J Clin Psychiatry. 2013 Oct; 74(10):966-73. PMID: 24229746.
      View in: PubMed
    27. Deligiannidis KM, Freeman MP. Complementary and alternative medicine therapies for perinatal depression. Best Pract Res Clin Obstet Gynaecol. 2014 Jan; 28(1):85-95. PMID: 24041861.
      View in: PubMed
    28. Deligiannidis KM, Sikoglu EM, Shaffer SA, Frederick B, Svenson AE, Kopoyan A, Kosma CA, Rothschild AJ, Moore CM. GABAergic neuroactive steroids and resting-state functional connectivity in postpartum depression: a preliminary study. J Psychiatr Res. 2013 Jun; 47(6):816-28. PMID: 23499388.
      View in: PubMed
    29. Byatt N, Deligiannidis KM, Freeman MP. Antidepressant use in pregnancy: a critical review focused on risks and controversies. Acta Psychiatr Scand. 2013 Feb; 127(2):94-114. PMID: 23240634.
      View in: PubMed
    30. Deligiannidis KM, Girgis RR, Lau A, Balon R, Zisook S. Psychiatry resident/fellow-initiated and -designed multi-modal psychopharmacology curriculum for major depression. Acad Psychiatry. 2012 Sep 1; 36(5):414-8. PMID: 22983477.
      View in: PubMed
    31. Deligiannidis KM. Psychiatry Issue Briefs. Depression in women during childbearing years: causes, symptoms, challenges and treatment. 2011; 8(1).
    32. Moore Simas T, Byatt N, Deligiannidis KM. Alternative and Complementary Therapies. Clinical Roundup: How do you treat premenstrual syndrome in your practice?. 2011; 17(4):237.
    33. Prabhakar D, Balon R, Deligiannidis, KM, Zisook S. . Revista de Trastornos del Ánimo. The American Society for Clinical Psychopharmacology’s Modules in Depression and Bipolar Disorder: Answering the Call for a Model Curriculum. 2011; 1(7):8-13.
    34. Deligiannidis KM, Freeman MP. Complementary and alternative medicine for the treatment of depressive disorders in women. Psychiatr Clin North Am. 2010 Jun; 33(2):441-63. PMID: 20385346.
      View in: PubMed
    35. Deligiannidis KM. Therapeutic drug monitoring in pregnant and postpartum women: recommendations for SSRIs, lamotrigine, and lithium. J Clin Psychiatry. 2010 May; 71(5):649-50. PMID: 20492855.
      View in: PubMed
    36. Marsh WK, Deligiannidis KM. Current Psychiatry. Sex-related differences in antidepressant response: When to adjust treatment. 2010; 9(5):25-30.
    37. Meyers BS, Flint AJ, Rothschild AJ, Mulsant BH, Whyte EM, Peasley-Miklus C, Papademetriou E, Leon AC, Heo M. A double-blind randomized controlled trial of olanzapine plus sertraline vs olanzapine plus placebo for psychotic depression: the study of pharmacotherapy of psychotic depression (STOP-PD). Arch Gen Psychiatry. 2009 Aug; 66(8):838-47. PMID: 19652123.
      View in: PubMed
    38. Falcón J, Galarneau KM, Weller JL, Ron B, Chen G, Coon SL, Klein DC. Regulation of arylalkylamine N-acetyltransferase-2 (AANAT2, EC in the fish pineal organ: evidence for a role of proteasomal proteolysis. Endocrinology. 2001 May; 142(5):1804-13. PMID: 11316744.
      View in: PubMed
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