Hassan Fakih to RNA, Small Interfering
This is a "connection" page, showing publications Hassan Fakih has written about RNA, Small Interfering.
Connection Strength
2.091
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Fakih HH, Zain Ui Abideen M, Rachid MO, Gross KY, Ormsby TJR, Ross VM, Gagnon R, Dahlke C, Furgal RC, Lochmann C, Summers A, Sleiman HF, F?rst SM, Jackson SN, Gordilho JO, Bouix-Peter C, Portal T, Tang Q, Harris JE, Khvorova A, Blanchard C, Alterman JF. Intradermal delivery of lipophilic siRNAs enables prolonged skin retention and sustained gene silencing in a porcine model. Nat Commun. 2026 Feb 03; 17(1).
Score: 0.593
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Fakih HH, Lochmann C, Gagnon R, Summers A, Caiazzi J, Buchwald JE, Tang Q, Maru B, Hildebrand SR, Abideen MZUI, Furgal RC, Gross KY, Yang YS, Cooper D, Monopoli KR, Echeverria D, Shim JH, Yamada K, Alterman JF, Khvorova A. Potent and durable gene modulation in heart and muscle with chemically defined lipophilic siRNAs. Nucleic Acids Res. 2025 Nov 26; 53(22).
Score: 0.586
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Tocheny CE, Buchwald JE, Dahlke CD, Fakih HH, Morgan JS, Summers A, Silva CA, Jackson SO, Lee JS, Card MA, Echeverria D, Peterson C, Mercurio AM, Khvorova A, Shaw LM. Therapeutic delivery of albumin-binding siRNA targeting IRS2 to diverse cell types reduces mammary tumor growth. Mol Ther. 2026 May 06; 34(5):2963-2982.
Score: 0.148
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O'Reilly D, Furgal RC, Ross VM, Luu E, Gross KY, Hariharan V, Summers A, Cooper D, Allen S, Dahlke C, Rachid MO, Chan IL, Fakih HH, Alterman JF, Echeverria D, Watts JK, Khvorova A. Presence of phosphodiester backbone, but not nucleobases, in the guide's 3' terminal region is necessary for RISC loading and target cleavage in vitro and in vivo. Nucleic Acids Res. 2026 Jan 05; 54(1).
Score: 0.148
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Yamada K, Hariharan VN, Caiazzi J, Miller R, Ferguson CM, Sapp E, Fakih HH, Tang Q, Yamada N, Furgal RC, Paquette JD, Biscans A, Bramato BM, McHugh N, Summers A, Lochmann C, Godinho BMDC, Hildebrand S, Jackson SO, Echeverria D, Hassler MR, Alterman JF, DiFiglia M, Aronin N, Khvorova A. Enhancing siRNA efficacy in vivo with extended nucleic acid backbones. Nat Biotechnol. 2025 Jun; 43(6):904-913.
Score: 0.134
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Sarli SL, Fakih HH, Kelly K, Devi G, Rembetsy-Brown JM, McEachern HR, Ferguson CM, Echeverria D, Lee J, Sousa J, Sleiman HF, Khvorova A, Watts JK. Quantifying the activity profile of ASO and siRNA conjugates in glioblastoma xenograft tumors in vivo. Nucleic Acids Res. 2024 05 22; 52(9):4799-4817.
Score: 0.132
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Habibian M, Harikrishna S, Fakhoury J, Barton M, Ageely EA, Cencic R, Fakih HH, Katolik A, Takahashi M, Rossi J, Pelletier J, Gagnon KT, Pradeepkumar PI, Damha MJ. Effect of 2'-5'/3'-5' phosphodiester linkage heterogeneity on RNA interference. Nucleic Acids Res. 2020 05 21; 48(9):4643-4657.
Score: 0.100
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Fakih HH, Fakhoury JJ, Bousmail D, Sleiman HF. Minimalist Design of a Stimuli-Responsive Spherical Nucleic Acid for Conditional Delivery of Oligonucleotide Therapeutics. ACS Appl Mater Interfaces. 2019 Apr 17; 11(15):13912-13920.
Score: 0.091
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Bujold KE, Fakih HH, Sleiman HF. Design Strategy to Access siRNA-Encapsulating DNA "Nanosuitcases" That Can Conditionally Release Their Cargo. Methods Mol Biol. 2019; 1974:69-81.
Score: 0.091
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Blitek M, Le Coz O, Ogor V, Fakih HH, Khvorova A, Goyenvalle A. Efficient Downregulation of Flt-1 Mediated by Splice Switching ASO in Murine Endothelial Cells. Nucleic Acid Ther. 2026 Jun; 36(3):147-157.
Score: 0.037
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Tang Q, Fakih HH, Zain Ui Abideen M, Hildebrand SR, Afshari K, Gross KY, Sousa J, Maebius AS, Bartholdy C, S?gaard PP, Jackerott M, Hariharan V, Summers A, Fan X, Okamura K, Monopoli KR, Cooper DA, Echeverria D, Bramato B, McHugh N, Furgal RC, Dresser K, Winter SJ, Biscans A, Chuprin J, Haddadi NS, Sherman S, Yildiz-Altay ?, Rashighi M, Richmond JM, Bouix-Peter C, Blanchard C, Clauss A, Alterman JF, Khvorova A, Harris JE. Rational design of a JAK1-selective siRNA inhibitor for the modulation of autoimmunity in the skin. Nat Commun. 2023 11 04; 14(1):7099.
Score: 0.032