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Stephen P Baker MScPH

TitleAssistant Professor
InstitutionUniversity of Massachusetts Medical School
DepartmentPopulation and Quantitative Health Sciences
AddressUniversity of Massachusetts Medical School
55 Lake Avenue North
Worcester MA 01655
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    Other Positions
    InstitutionUMMS - School of Medicine
    DepartmentCell and Developmental Biology

    InstitutionUMMS - School of Medicine
    DepartmentPopulation and Quantitative Health Sciences
    DivisionBiostatistics And Health Services Research


    Collapse Biography 
    Collapse education and training
    Worcester State College, Worcester, MA, United StatesBSPSYCHOLOGY
    University of Massachusetts Amherst, Amherst, MA, United StatesMPHBIOSTATISTICS
    University of Massachusetts Amherst School of Public Health, Amherst, MAPhD (abd)Biostatistics

    Collapse Overview 
    Collapse overview
    Academic Appointments
  • 1983-Present, The University of Massachusetts Medical School:
  • 2004-Present, Instructor in Biostatistics, Dept. of Cell Biology
  • 1992-Present, Associate Faculty, Graduate School of Nursing,
  • 1986-2004, Lecturer of Biomedical Sciences in Biostatistics, Graduate School of Biomed¬ical Sciences .
  • Professional Positions
  • 1983-Present, The University of Massachusetts Medical School:
  • 1998-Present, Senior Biostatistician, Academic Computing Services
  • 1997-1998, Director of Research and Evaluation, Office of Clinical Affairs, Executive Office of Health and Human Services, Division of Medical Assistance and The University of Massachusetts Medical School Commonwealth Medicine Program.
  • 1990-1991 Associate Director for Academic Computing Programs, Department of Academic Computing
  • 1983-1997, Biostatistician, Department of Academic Computing.
  • 1980-1983, The University of Massachusetts, Amherst:
  • 1981-1983, Project Statistician, Mastitis Control Program, Lactation and Reproductive Physiology Laboratories, Dept. of Veterinary and Animal Science.
  • 1980-1981, Research Assistant, Biopharmaceutical Research Unit, Department of Biostatistics and Epidemiology, School of Public Health
  • 1973-1980 Astra Pharmaceutical Products, Inc., Framingham Massachusetts:
  • 1976-1980, Clinical Research Monitor, Cardiovascular And Psychotropic Drug Development Programs, Medical Department
  • 1973-1976, Clinical Data Analyst, Pulmonary, Pain Control And Cardiovas¬cular Drug Development Programs, Medical Department
  • Editorial Activities
  • Editorial Board Member
  • Chest
  • Referee:
  • Bioinformatics
  • Chest
  • Clinical Infectious Disease
  • The Journal of Clinical Care Medicine
  • The Journal of Clinical Endocrinology and Metabolism
  • The Journal of Physiology
  • Statistical Research
  • General and Generalized linear mixed models
  • Missing Data problems
  • Multiple Comparisons Procedures
  • Problems in estimation in finite populations.
  • Methods for the analysis of microarray experiments
  • Professional Memberships
  • American Statistical Association
  • The Biometric Society (ENAR)
  • The International Biometric Society



    • Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Velagapudi V, O'Horo JC, Vellanki A, Baker SP, Pidikiti R, Stoff JS, Tighe DA. Computer-assisted image processing 12 lead ECG model to diagnose hyperkalemia. J Electrocardiol. 2017 Jan - Feb; 50(1):131-138. PMID: 27662777.
      View in: PubMed
    2. Smyrnios NA, Lenard R, Rajan S, Newman MS, Baker SP, Thakkar N, Wassef W, Ajmere NK, Irwin RS. Comparison of a self-inflating bulb syringe and a colorimetric CO2 indicator with capnography and radiography to detect the misdirection of naso/orogastric tubes into the airway of critically ill adult patients. Chest. 2015 Jun; 147(6):1523-9. PMID: 25674721.
      View in: PubMed
    3. Walz JM, Ellison RT, Mack DA, Flaherty HM, McIlwaine JK, Whyte KG, Landry KE, Baker SP, Heard SO. The bundle "plus": the effect of a multidisciplinary team approach to eradicate central line-associated bloodstream infections. Anesth Analg. 2015 Apr; 120(4):868-76. PMID: 24149581.
      View in: PubMed
    4. Lilly CM, Landry KE, Sood RN, Ellison RT, Bagley PH, Baker SP, Cody S, Irwin RS. The authors reply. Crit Care Med. 2015 Feb; 43(2):e61-2. PMID: 25599510.
      View in: PubMed
    5. Lilly CM, Landry KE, Sood RN, Dunnington CH, Ellison RT, Bagley PH, Baker SP, Cody S, Irwin RS. Prevalence and test characteristics of national health safety network ventilator-associated events. Crit Care Med. 2014 Sep; 42(9):2019-28. PMID: 24810522.
      View in: PubMed
    6. Lilly CM, McLaughlin JM, Zhao H, Baker SP, Cody S, Irwin RS. A multicenter study of ICU telemedicine reengineering of adult critical care. Chest. 2014 Mar 1; 145(3):500-7. PMID: 24306581.
      View in: PubMed
    7. Ellis KA, Hosseinnezhad A, Ullah A, Vinagre YM, Baker SP, Lilly CM. Prehospital management of evolving critical illness by the primary care provider. Chest. 2013 Oct; 144(4):1216-21. PMID: 23788252.
      View in: PubMed
    8. Vedantham S, Karellas A, Emmons MM, Moss LJ, Hussain S, Baker SP. Dedicated breast CT: geometric design considerations to maximize posterior breast coverage. Phys Med Biol. 2013 Jun 21; 58(12):4099-118. PMID: 23685899.
      View in: PubMed
    9. Silverman J, Baker SP, Lidz CW. A self-assessment survey of the Institutional Animal Care and Use Committee, part 2: structure and organizational functions. Lab Anim (NY). 2012 Oct; 41(10):289-94. PMID: 22992507.
      View in: PubMed
    10. Silverman J, Baker SP, Lidz CW. A self-assessment survey of the Institutional Animal Care and Use Committee, Part 1: animal welfare and protocol compliance. Lab Anim (NY). 2012 Aug; 41(8):230-5. PMID: 22821046.
      View in: PubMed
    11. Henninger N, Lin E, Baker SP, Wakhloo AK, Takhtani D, Moonis M. Leukoaraiosis predicts poor 90-day outcome after acute large cerebral artery occlusion. Cerebrovasc Dis. 2012; 33(6):525-31. PMID: 22538962.
      View in: PubMed
    12. Chin MS, Freniere BB, Lo YC, Saleeby JH, Baker SP, Strom HM, Ignotz RA, Lalikos JF, Fitzgerald TJ. Hyperspectral imaging for early detection of oxygenation and perfusion changes in irradiated skin. J Biomed Opt. 2012 Feb; 17(2):026010. PMID: 22463042.
      View in: PubMed
    13. Jonassen JA, SanAgustin J, Baker SP, Pazour GJ. Disruption of IFT complex A causes cystic kidneys without mitotic spindle misorientation. J Am Soc Nephrol. 2012 Apr; 23(4):641-51. PMID: 22282595.
      View in: PubMed
    14. Corwin MT, Karam AR, Baker SP, Kim YH. Determination of cystic duct patency using hepatobiliary MRI with gadoxetate disodium: is T1 precontrast imaging necessary? J Magn Reson Imaging. 2012 Mar; 35(3):601-6. PMID: 22034256.
      View in: PubMed
    15. Lilly CM, Cody S, Zhao H, Landry K, Baker SP, McIlwaine J, Chandler MW, Irwin RS. Hospital mortality, length of stay, and preventable complications among critically ill patients before and after tele-ICU reengineering of critical care processes. JAMA. 2011 Jun 1; 305(21):2175-83. PMID: 21576622.
      View in: PubMed
    16. Mellios N, Galdzicka M, Ginns E, Baker SP, Rogaev E, Xu J, Akbarian S. Gender-specific reduction of estrogen-sensitive small RNA, miR-30b, in subjects with schizophrenia. Schizophr Bull. 2012 May; 38(3):433-43. PMID: 20732949.
      View in: PubMed
    17. Baker SP, Phillips J, Anderson S, Qiu Q, Shabanowitz J, Smith MM, Yates JR, Hunt DF, Grant PA. Histone H3 Thr 45 phosphorylation is a replication-associated post-translational modification in S. cerevisiae. Nat Cell Biol. 2010 Mar; 12(3):294-8. PMID: 20139971.
      View in: PubMed
    18. Evans BA, Evans JE, Baker SP, Kane K, Swearer J, Hinerfeld D, Caselli R, Rogaeva E, St George-Hyslop P, Moonis M, Pollen DA. Long-term statin therapy and CSF cholesterol levels: implications for Alzheimer's disease. Dement Geriatr Cogn Disord. 2009; 27(6):519-24. PMID: 19478483.
      View in: PubMed
    19. Silverman J, Bays DW, Baker SP. Ammonia and carbon dioxide concentrations in disposable and reusable static mouse cages. Lab Anim (NY). 2009 Jan; 38(1):16-23. PMID: 19112446.
      View in: PubMed
    20. Mellios N, Huang HS, Baker SP, Galdzicka M, Ginns E, Akbarian S. Molecular determinants of dysregulated GABAergic gene expression in the prefrontal cortex of subjects with schizophrenia. Biol Psychiatry. 2009 Jun 15; 65(12):1006-14. PMID: 19121517.
      View in: PubMed
    21. Tresoldi S, Kim YH, Blake MA, Harisinghani MG, Hahn PF, Baker SP, Mueller PR, Kandarpa K. Adult intestinal intussusception: can abdominal MDCT distinguish an intussusception caused by a lead point? Abdom Imaging. 2008 Sep-Oct; 33(5):582-8. PMID: 17924160.
      View in: PubMed
    22. Silverman J, Bays DW, Cooper SF, Baker SP. Ammonia and carbon dioxide concentrations in disposable and reusable ventilated mouse cages. J Am Assoc Lab Anim Sci. 2008 Mar; 47(2):57-62. PMID: 18351723.
      View in: PubMed
    23. Hinerfeld DA, Moonis M, Swearer JM, Baker SP, Caselli RJ, Rogaeva E, St George-Hyslop P, Pollen DA. Statins differentially affect amyloid precursor protein metabolism in presymptomatic PS1 and non-PS1 subjects. Arch Neurol. 2007 Nov; 64(11):1672-3. PMID: 17998454.
      View in: PubMed
    24. Huang HS, Matevossian A, Whittle C, Kim SY, Schumacher A, Baker SP, Akbarian S. Prefrontal dysfunction in schizophrenia involves mixed-lineage leukemia 1-regulated histone methylation at GABAergic gene promoters. J Neurosci. 2007 Oct 17; 27(42):11254-62. PMID: 17942719.
      View in: PubMed
    25. Calvo-Calle JM, Strug I, Nastke MD, Baker SP, Stern LJ. Human CD4+ T cell epitopes from vaccinia virus induced by vaccination or infection. PLoS Pathog. 2007 Oct 12; 3(10):1511-29. PMID: 17937498.
      View in: PubMed
    26. Istvanic S, Yantiss RK, Baker SP, Banner BF. Normal variation in intraepithelial lymphocytes of the terminal ileum. Am J Clin Pathol. 2007 May; 127(5):816-9. PMID: 17439842.
      View in: PubMed
    27. Lai KK, Fontecchio S, Melvin Z, Baker SP. Impact of alcohol-based, waterless hand antiseptic on the incidence of infection and colonization with methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococci. Infect Control Hosp Epidemiol. 2006 Oct; 27(10):1018-24. PMID: 17006807.
      View in: PubMed
    28. De Crescenzo V, Fogarty KE, Zhuge R, Tuft RA, Lifshitz LM, Carmichael J, Bellvé KD, Baker SP, Zissimopoulos S, Lai FA, Lemos JR, Walsh JV. Dihydropyridine receptors and type 1 ryanodine receptors constitute the molecular machinery for voltage-induced Ca2+ release in nerve terminals. J Neurosci. 2006 Jul 19; 26(29):7565-74. PMID: 16855084.
      View in: PubMed
    29. Morse AN, O'dell KK, Howard AE, Baker SP, Aronson MP, Young SB. Midline anterior repair alone vs anterior repair plus vaginal paravaginal repair: a comparison of anatomic and quality of life outcomes. Int Urogynecol J Pelvic Floor Dysfunct. 2007 Mar; 18(3):245-9. PMID: 16823542.
      View in: PubMed
    30. Yousef MM, Yantiss RK, Baker SP, Banner BF. Duodenal intraepithelial lymphocytes in inflammatory disorders of the esophagus and stomach. Clin Gastroenterol Hepatol. 2006 May; 4(5):631-4. PMID: 16630772.
      View in: PubMed
    31. Huang J, Kim YH, Shankar S, Tyagi G, Baker SP. Multidetector CT urography: comparison of two different scanning protocols for improved visualization of the urinary tract. J Comput Assist Tomogr. 2006 Jan-Feb; 30(1):33-6. PMID: 16365569.
      View in: PubMed
    32. Patel PK, Arcangioli B, Baker SP, Bensimon A, Rhind N. DNA replication origins fire stochastically in fission yeast. Mol Biol Cell. 2006 Jan; 17(1):308-16. PMID: 16251353.
      View in: PubMed
    33. Akbarian S, Ruehl MG, Bliven E, Luiz LA, Peranelli AC, Baker SP, Roberts RC, Bunney WE, Conley RC, Jones EG, Tamminga CA, Guo Y. Chromatin alterations associated with down-regulated metabolic gene expression in the prefrontal cortex of subjects with schizophrenia. Arch Gen Psychiatry. 2005 Aug; 62(8):829-40. PMID: 16061760.
      View in: PubMed
    34. Stadler F, Kolb G, Rubusch L, Baker SP, Jones EG, Akbarian S. Histone methylation at gene promoters is associated with developmental regulation and region-specific expression of ionotropic and metabotropic glutamate receptors in human brain. J Neurochem. 2005 Jul; 94(2):324-36. PMID: 15998284.
      View in: PubMed
    35. Aronson MP, Aronson PK, Howard AE, Morse AN, Baker SP, Young SB. Low risk of ureteral obstruction with "deep" (dorsal/posterior) uterosacral ligament suture placement for transvaginal apical suspension. Am J Obstet Gynecol. 2005 May; 192(5):1530-6. PMID: 15902153.
      View in: PubMed
    36. Hake SB, Garcia BA, Kauer M, Baker SP, Shabanowitz J, Hunt DF, Allis CD. Serine 31 phosphorylation of histone variant H3.3 is specific to regions bordering centromeres in metaphase chromosomes. Proc Natl Acad Sci U S A. 2005 May 3; 102(18):6344-9. PMID: 15851689.
      View in: PubMed
    37. Li Y, Ayata G, Baker SP, Banner BF. Cholangitis: a histologic classification based on patterns of injury in liver biopsies. Pathol Res Pract. 2005; 201(8-9):565-72. PMID: 16259109.
      View in: PubMed
    38. Wu X, Arumugam R, Baker SP, Lee MM. Pubertal and adult Leydig cell function in Mullerian inhibiting substance-deficient mice. Endocrinology. 2005 Feb; 146(2):589-95. PMID: 15514087.
      View in: PubMed
    39. Lai KK, Baker SP, Fontecchio SA. Rapid eradication of a cluster of Serratia marcescens in a neonatal intensive care unit: use of epidemiologic chromosome profiling by pulsed-field gel electrophoresis. Infect Control Hosp Epidemiol. 2004 Sep; 25(9):730-4. PMID: 15484796.
      View in: PubMed
    40. Zhuge R, Fogarty KE, Baker SP, McCarron JG, Tuft RA, Lifshitz LM, Walsh JV. Ca(2+) spark sites in smooth muscle cells are numerous and differ in number of ryanodine receptors, large-conductance K(+) channels, and coupling ratio between them. Am J Physiol Cell Physiol. 2004 Dec; 287(6):C1577-88. PMID: 15306542.
      View in: PubMed
    41. Li JM, Singh MJ, Itani M, Vasiliu C, Hendricks G, Baker SP, Hale JE, Rohrer MJ, Cutler BS, Nelson PR. Recombinant human thrombomodulin inhibits arterial neointimal hyperplasia after balloon injury. J Vasc Surg. 2004 May; 39(5):1074-83. PMID: 15111864.
      View in: PubMed
    42. Young SB, Kohorn EI, Braz-Martin S, Baker SP. A survey of the complications of vaginal prolapse surgery performed by members of the Society Of Gynecologic Surgeons. Int Urogynecol J Pelvic Floor Dysfunct. 2004 May-Jun; 15(3):165-70. PMID: 15167994.
      View in: PubMed
    43. Lai KK, Baker SP, Fontecchio SA. Impact of a program of intensive surveillance and interventions targeting ventilated patients in the reduction of ventilator-associated pneumonia and its cost-effectiveness. Infect Control Hosp Epidemiol. 2003 Nov; 24(11):859-63. PMID: 14649776.
      View in: PubMed
    44. Suryanarayanan S, Karellas A, Vedantham S, Ved H, Baker SP, D'Orsi CJ. Flat-panel digital mammography system: contrast-detail comparison between screen-film radiographs and hard-copy images. Radiology. 2002 Dec; 225(3):801-7. PMID: 12461264.
      View in: PubMed
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