Leonard Shultz to Female
This is a "connection" page, showing publications Leonard Shultz has written about Female.
Connection Strength
0.773
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Brehm MA, Kenney LL, Wiles MV, Low BE, Tisch RM, Burzenski L, Mueller C, Greiner DL, Shultz LD. Lack of acute xenogeneic graft- versus-host disease, but retention of T-cell function following engraftment of human peripheral blood mononuclear cells in NSG mice deficient in MHC class I and II expression. FASEB J. 2019 03; 33(3):3137-3151.
Score: 0.034
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Hosur V, Cox ML, Burzenski LM, Riding RL, Alley L, Lyons BL, Kavirayani A, Martin KA, Cox GA, Johnson KR, Shultz LD. Retrotransposon insertion in the T-cell acute lymphocytic leukemia 1 (Tal1) gene is associated with severe renal disease and patchy alopecia in Hairpatches (Hpt) mice. PLoS One. 2013; 8(1):e53426.
Score: 0.023
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Wilson DW, Oslund KL, Lyons B, Foreman O, Burzenski L, Svenson KL, Chase TH, Shultz LD. Inflammatory dilated cardiomyopathy in Abcg5-deficient mice. Toxicol Pathol. 2013 Aug; 41(6):880-92.
Score: 0.023
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Hosur V, Kavirayani A, Riefler J, Carney LM, Lyons B, Gott B, Cox GA, Shultz LD. Dystrophin and dysferlin double mutant mice: a novel model for rhabdomyosarcoma. Cancer Genet. 2012 May; 205(5):232-41.
Score: 0.022
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Foreman O, Kavirayani AM, Griffey SM, Reader R, Shultz LD. Opportunistic bacterial infections in breeding colonies of the NSG mouse strain. Vet Pathol. 2011 Mar; 48(2):495-9.
Score: 0.020
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Pino S, Brehm MA, Covassin-Barberis L, King M, Gott B, Chase TH, Wagner J, Burzenski L, Foreman O, Greiner DL, Shultz LD. Development of novel major histocompatibility complex class I and class II-deficient NOD-SCID IL2R gamma chain knockout mice for modeling human xenogeneic graft-versus-host disease. Methods Mol Biol. 2010; 602:105-17.
Score: 0.019
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Chase TH, Lyons BL, Bronson RT, Foreman O, Donahue LR, Burzenski LM, Gott B, Lane P, Harris B, Ceglarek U, Thiery J, Wittenburg H, Thon JN, Italiano JE, Johnson KR, Shultz LD. The mouse mutation "thrombocytopenia and cardiomyopathy" (trac) disrupts Abcg5: a spontaneous single gene model for human hereditary phytosterolemia/sitosterolemia. Blood. 2010 Feb 11; 115(6):1267-76.
Score: 0.018
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Pearson T, Greiner DL, Shultz LD. Creation of "humanized" mice to study human immunity. Curr Protoc Immunol. 2008 May; Chapter 15:15.21.1-15.21.21.
Score: 0.017
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Lyons BL, Smith RS, Hurd RE, Hawes NL, Burzenski LM, Nusinowitz S, Hasham MG, Chang B, Shultz LD. Deficiency of SHP-1 protein-tyrosine phosphatase in "viable motheaten" mice results in retinal degeneration. Invest Ophthalmol Vis Sci. 2006 Mar; 47(3):1201-9.
Score: 0.014
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Shultz LD, Lyons BL, Burzenski LM, Gott B, Chen X, Chaleff S, Kotb M, Gillies SD, King M, Mangada J, Greiner DL, Handgretinger R. Human lymphoid and myeloid cell development in NOD/LtSz-scid IL2R gamma null mice engrafted with mobilized human hemopoietic stem cells. J Immunol. 2005 May 15; 174(10):6477-89.
Score: 0.014
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Amdare NP, Shultz LD, Greiner DL, DiLorenzo TP. Human insulin as both antigen and protector in type 1 diabetes. Eur J Immunol. 2024 Sep; 54(9):e2350949.
Score: 0.013
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Hasanali ZS, Garfall AL, Burzenski L, Shultz LD, Tang Y, Kadu S, Sheppard NC, Liu W, Dopkin D, Vogl DT, Cohen AD, Waxman AJ, Susanibar-Adaniya SP, Carroll M, Stadtmauer EA, Allman D. Human IL-6 fosters long-term engraftment of patient-derived disease-driving myeloma cells in immunodeficient mice. JCI Insight. 2024 May 07; 9(10).
Score: 0.013
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Joliat MJ, Lang PA, Lyons BL, Burzenski L, Lynes MA, Yi T, Sundberg JP, Shultz LD. Absence of CD5 dramatically reduces progression of pulmonary inflammatory lesions in SHP-1 protein-tyrosine phosphatase-deficient 'viable motheaten' mice. J Autoimmun. 2002 Mar; 18(2):105-17.
Score: 0.011
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Bhatta M, Shenoy GN, Loyall JL, Gray BD, Bapardekar M, Conway A, Minderman H, Kelleher RJ, Carreno BM, Linette G, Shultz LD, Odunsi K, Balu-Iyer SV, Pak KY, Bankert RB. Novel phosphatidylserine-binding molecule enhances antitumor T-cell responses by targeting immunosuppressive exosomes in human tumor microenvironments. J Immunother Cancer. 2021 10; 9(10).
Score: 0.011
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Jiang L, Wang YJ, Zhao J, Uehara M, Hou Q, Kasinath V, Ichimura T, Banouni N, Dai L, Li X, Greiner DL, Shultz LD, Zhang X, Sun ZJ, Curtin I, Vangos NE, Yeoh ZC, Geffken EA, Seo HS, Liu ZX, Heffron GJ, Shah K, Dhe-Paganon S, Abdi R. Direct Tumor Killing and Immunotherapy through Anti-SerpinB9 Therapy. Cell. 2020 11 25; 183(5):1219-1233.e18.
Score: 0.010
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Li P, Lu M, Shi J, Gong Z, Hua L, Li Q, Lim B, Zhang XH, Chen X, Li S, Shultz LD, Ren G. Lung mesenchymal cells elicit lipid storage in neutrophils that fuel breast cancer lung metastasis. Nat Immunol. 2020 11; 21(11):1444-1455.
Score: 0.010
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Li P, Lu M, Shi J, Hua L, Gong Z, Li Q, Shultz LD, Ren G. Dual roles of neutrophils in metastatic colonization are governed by the host NK cell status. Nat Commun. 2020 09 01; 11(1):4387.
Score: 0.010
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Ye C, Yang H, Cheng M, Shultz LD, Greiner DL, Brehm MA, Keck JG. A rapid, sensitive, and reproducible in vivo PBMC humanized murine model for determining therapeutic-related cytokine release syndrome. FASEB J. 2020 09; 34(9):12963-12975.
Score: 0.010
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Dai C, Walker JT, Shostak A, Bouchi Y, Poffenberger G, Hart NJ, Jacobson DA, Calcutt MW, Bottino R, Greiner DL, Shultz LD, McGuinness OP, Dean ED, Powers AC. Dapagliflozin Does Not Directly Affect Human a or ? Cells. Endocrinology. 2020 08 01; 161(8).
Score: 0.010
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Hosur V, Low BE, Li D, Stafford GA, Kohar V, Shultz LD, Wiles MV. Genes adapt to outsmart gene-targeting strategies in mutant mouse strains by skipping exons to reinitiate transcription and translation. Genome Biol. 2020 07 09; 21(1):168.
Score: 0.010
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Shimada-Hiratsuka M, Naito M, Kaizu C, Shuying J, Hasegawa G, Shultz LD. Defective macrophage recruitment and clearance of apoptotic cells in the uterus of osteopetrotic mutant mice lacking macrophage colony-stimulating factor (M-CSF). J Submicrosc Cytol Pathol. 2000 Apr; 32(2):297-307.
Score: 0.010
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Shultz LD, Lang PA, Christianson SW, Gott B, Lyons B, Umeda S, Leiter E, Hesselton R, Wagar EJ, Leif JH, Kollet O, Lapidot T, Greiner DL. NOD/LtSz-Rag1null mice: an immunodeficient and radioresistant model for engraftment of human hematolymphoid cells, HIV infection, and adoptive transfer of NOD mouse diabetogenic T cells. J Immunol. 2000 Mar 01; 164(5):2496-507.
Score: 0.009
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Redick SD, Leehy L, Rittenhouse AR, Blodgett DM, Derr AG, Kucukural A, Garber MG, Shultz LD, Greiner DL, Wang JP, Harlan DM, Bortell R, Jurczyk A. Recovery of viable endocrine-specific cells and transcriptomes from human pancreatic islet-engrafted mice. FASEB J. 2020 01; 34(1):1901-1911.
Score: 0.009
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Wagenblast E, Azkanaz M, Smith SA, Shakib L, McLeod JL, Krivdova G, Ara?jo J, Shultz LD, Gan OI, Dick JE, Lechman ER. Functional profiling of single CRISPR/Cas9-edited human long-term hematopoietic stem cells. Nat Commun. 2019 10 18; 10(1):4730.
Score: 0.009
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Matsuda M, Ono R, Iyoda T, Endo T, Iwasaki M, Tomizawa-Murasawa M, Saito Y, Kaneko A, Shimizu K, Yamada D, Ogonuki N, Watanabe T, Nakayama M, Koseki Y, Kezuka-Shiotani F, Hasegawa T, Yabe H, Kato S, Ogura A, Shultz LD, Ohara O, Taniguchi M, Koseki H, Fujii SI, Ishikawa F. Human NK cell development in hIL-7 and hIL-15 knockin NOD/SCID/IL2rgKO mice. Life Sci Alliance. 2019 04; 2(2).
Score: 0.009
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Bahmani B, Uehara M, Ordikhani F, Li X, Jiang L, Banouni N, Ichimura T, Kasinath V, Eskandari SK, Annabi N, Bromberg JS, Shultz LD, Greiner DL, Abdi R. Ectopic high endothelial venules in pancreatic ductal adenocarcinoma: A unique site for targeted delivery. EBioMedicine. 2018 Dec; 38:79-88.
Score: 0.009
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Brissova M, Haliyur R, Saunders D, Shrestha S, Dai C, Blodgett DM, Bottino R, Campbell-Thompson M, Aramandla R, Poffenberger G, Lindner J, Pan FC, von Herrath MG, Greiner DL, Shultz LD, Sanyoura M, Philipson LH, Atkinson M, Harlan DM, Levy SE, Prasad N, Stein R, Powers AC. a Cell Function and Gene Expression Are Compromised in Type 1 Diabetes. Cell Rep. 2018 03 06; 22(10):2667-2676.
Score: 0.008
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Wang M, Yao LC, Cheng M, Cai D, Martinek J, Pan CX, Shi W, Ma AH, De Vere White RW, Airhart S, Liu ET, Banchereau J, Brehm MA, Greiner DL, Shultz LD, Palucka K, Keck JG. Humanized mice in studying efficacy and mechanisms of PD-1-targeted cancer immunotherapy. FASEB J. 2018 03; 32(3):1537-1549.
Score: 0.008
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Saito Y, Mochizuki Y, Ogahara I, Watanabe T, Hogdal L, Takagi S, Sato K, Kaneko A, Kajita H, Uchida N, Fukami T, Shultz LD, Taniguchi S, Ohara O, Letai AG, Ishikawa F. Overcoming mutational complexity in acute myeloid leukemia by inhibition of critical pathways. Sci Transl Med. 2017 Oct 25; 9(413).
Score: 0.008
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Dai C, Hang Y, Shostak A, Poffenberger G, Hart N, Prasad N, Phillips N, Levy SE, Greiner DL, Shultz LD, Bottino R, Kim SK, Powers AC. Age-dependent human ? cell proliferation induced by glucagon-like peptide 1 and calcineurin signaling. J Clin Invest. 2017 Oct 02; 127(10):3835-3844.
Score: 0.008
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Serreze DV, Chapman HD, Varnum DS, Gerling I, Leiter EH, Shultz LD. Initiation of autoimmune diabetes in NOD/Lt mice is MHC class I-dependent. J Immunol. 1997 Apr 15; 158(8):3978-86.
Score: 0.008
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Miller PH, Rabu G, MacAldaz M, Knapp DJ, Cheung AM, Dhillon K, Nakamichi N, Beer PA, Shultz LD, Humphries RK, Eaves CJ. Analysis of parameters that affect human hematopoietic cell outputs in mutant c-kit-immunodeficient mice. Exp Hematol. 2017 04; 48:41-49.
Score: 0.008
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Sundberg JP, France M, Boggess D, Sundberg BA, Jenson AB, Beamer WG, Shultz LD. Development and progression of psoriasiform dermatitis and systemic lesions in the flaky skin (fsn) mouse mutant. Pathobiology. 1997; 65(5):271-86.
Score: 0.008
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Cheng F, Twardowski L, Reifenberg K, Winter K, Canisius A, Pross E, Fan J, Schmitt E, Shultz LD, Lackner KJ, Torzewski M. Combined B, T and NK Cell Deficiency Accelerates Atherosclerosis in BALB/c Mice. PLoS One. 2016; 11(8):e0157311.
Score: 0.007
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Christianson SW, Greiner DL, Schweitzer IB, Gott B, Beamer GL, Schweitzer PA, Hesselton RM, Shultz LD. Role of natural killer cells on engraftment of human lymphoid cells and on metastasis of human T-lymphoblastoid leukemia cells in C57BL/6J-scid mice and in C57BL/6J-scid bg mice. Cell Immunol. 1996 Aug 01; 171(2):186-99.
Score: 0.007
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Noben-Trauth N, Schweitzer PA, Johnson KR, Wolf SF, Knowles BB, Shultz LD. The interleukin-12 beta subunit (p40) maps to mouse chromosome 11. Mamm Genome. 1996 May; 7(5):392.
Score: 0.007
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Schweitzer PA, Noben-Trauth N, Pelsue SC, Johnson KR, Wolf SF, Shultz LD. Genetic mapping of the IL-12 alpha chain gene (Il12a) on mouse chromosome 3. Mamm Genome. 1996 May; 7(5):394-5.
Score: 0.007
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Serr I, F?rst RW, Achenbach P, Scherm MG, G?kmen F, Haupt F, Sedlmeier EM, Knopff A, Shultz L, Willis RA, Ziegler AG, Daniel C. Type 1 diabetes vaccine candidates promote human Foxp3(+)Treg induction in humanized mice. Nat Commun. 2016 Mar 15; 7:10991.
Score: 0.007
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Najima Y, Tomizawa-Murasawa M, Saito Y, Watanabe T, Ono R, Ochi T, Suzuki N, Fujiwara H, Ohara O, Shultz LD, Yasukawa M, Ishikawa F. Induction of WT1-specific human CD8+ T cells from human HSCs in HLA class I Tg NOD/SCID/IL2rgKO mice. Blood. 2016 Feb 11; 127(6):722-34.
Score: 0.007
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Pelsue SC, Schweitzer PA, Beamer WG, Shultz LD. Mapping of the flaky skin (fsn) mutation on distal mouse chromosome 17. Mamm Genome. 1995 Oct; 6(10):758.
Score: 0.007
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Presa M, Chen YG, Grier AE, Leiter EH, Brehm MA, Greiner DL, Shultz LD, Serreze DV. The Presence and Preferential Activation of Regulatory T Cells Diminish Adoptive Transfer of Autoimmune Diabetes by Polyclonal Nonobese Diabetic (NOD) T Cell Effectors into NSG versus NOD-scid Mice. J Immunol. 2015 Oct 01; 195(7):3011-9.
Score: 0.007
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Tang Z, Dai S, He Y, Doty RA, Shultz LD, Sampson SB, Dai C. MEK guards proteome stability and inhibits tumor-suppressive amyloidogenesis via HSF1. Cell. 2015 Feb 12; 160(4):729-744.
Score: 0.007
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Shultz LD, Schweitzer PA, Christianson SW, Gott B, Schweitzer IB, Tennent B, McKenna S, Mobraaten L, Rajan TV, Greiner DL, et al. Multiple defects in innate and adaptive immunologic function in NOD/LtSz-scid mice. J Immunol. 1995 Jan 01; 154(1):180-91.
Score: 0.007
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Chang C, Goel HL, Gao H, Pursell B, Shultz LD, Greiner DL, Ingerpuu S, Patarroyo M, Cao S, Lim E, Mao J, McKee KK, Yurchenco PD, Mercurio AM. A laminin 511 matrix is regulated by TAZ and functions as the ligand for the a6B?1 integrin to sustain breast cancer stem cells. Genes Dev. 2015 Jan 01; 29(1):1-6.
Score: 0.007
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Aoki Y, Watanabe T, Saito Y, Kuroki Y, Hijikata A, Takagi M, Tomizawa D, Eguchi M, Eguchi-Ishimae M, Kaneko A, Ono R, Sato K, Suzuki N, Fujiki S, Koh K, Ishii E, Shultz LD, Ohara O, Mizutani S, Ishikawa F. Identification of CD34+ and CD34- leukemia-initiating cells in MLL-rearranged human acute lymphoblastic leukemia. Blood. 2015 Feb 05; 125(6):967-80.
Score: 0.007
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Maykel J, Liu JH, Li H, Shultz LD, Greiner DL, Houghton J. NOD-scidIl2rg (tm1Wjl) and NOD-Rag1 (null) Il2rg (tm1Wjl) : a model for stromal cell-tumor cell interaction for human colon cancer. Dig Dis Sci. 2014 Jun; 59(6):1169-79.
Score: 0.006
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Goel HL, Gritsko T, Pursell B, Chang C, Shultz LD, Greiner DL, Norum JH, Toftgard R, Shaw LM, Mercurio AM. Regulated splicing of the a6 integrin cytoplasmic domain determines the fate of breast cancer stem cells. Cell Rep. 2014 May 08; 7(3):747-61.
Score: 0.006
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Potter CS, Wang Z, Silva KA, Kennedy VE, Stearns TM, Burzenski L, Shultz LD, Hogenesch H, Sundberg JP. Chronic proliferative dermatitis in Sharpin null mice: development of an autoinflammatory disease in the absence of B and T lymphocytes and IL4/IL13 signaling. PLoS One. 2014; 9(1):e85666.
Score: 0.006
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Usuda H, Naito M, Umeda S, Takahashi K, Shultz LD. Ultrastructure of macrophages and dendritic cells in osteopetrosis (op) mutant mice lacking macrophage colony-stimulating factor (M-CSF/CSF-1) activity. J Submicrosc Cytol Pathol. 1994 Jan; 26(1):111-9.
Score: 0.006
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Beamer WG, Shultz KL, Tennent BJ, Shultz LD. Granulosa cell tumorigenesis in genetically hypogonadal-immunodeficient mice grafted with ovaries from tumor-susceptible donors. Cancer Res. 1993 Aug 15; 53(16):3741-6.
Score: 0.006
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Sundberg JP, Boggess D, Sundberg BA, Beamer WG, Shultz LD. Epidermal dendritic cell populations in the flaky skin mutant mouse. Immunol Invest. 1993 Jul; 22(5):389-401.
Score: 0.006
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Jim?nez-D?az MB, Viera S, Ib??ez J, Mulet T, Mag?n-Marchal N, Garuti H, G?mez V, Cort?s-Gil L, Mart?nez A, Ferrer S, Fraile MT, Calder?n F, Fern?ndez E, Shultz LD, Leroy D, Wilson DM, Garc?a-Bustos JF, Gamo FJ, Angulo-Barturen I. A new in vivo screening paradigm to accelerate antimalarial drug discovery. PLoS One. 2013; 8(6):e66967.
Score: 0.006
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Yokota SJ, Facciponte JG, Kelleher RJ, Shultz LD, Loyall JL, Parsons RR, Odunsi K, Frelinger JG, Lord EM, Gerber SA, Balu-Iyer SV, Bankert RB. Changes in ovarian tumor cell number, tumor vasculature, and T cell function monitored in vivo using a novel xenograft model. Cancer Immun. 2013; 13:11.
Score: 0.006
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Saito Y, Yuki H, Kuratani M, Hashizume Y, Takagi S, Honma T, Tanaka A, Shirouzu M, Mikuni J, Handa N, Ogahara I, Sone A, Najima Y, Tomabechi Y, Wakiyama M, Uchida N, Tomizawa-Murasawa M, Kaneko A, Tanaka S, Suzuki N, Kajita H, Aoki Y, Ohara O, Shultz LD, Fukami T, Goto T, Taniguchi S, Yokoyama S, Ishikawa F. A pyrrolo-pyrimidine derivative targets human primary AML stem cells in vivo. Sci Transl Med. 2013 Apr 17; 5(181):181ra52.
Score: 0.006
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Goel HL, Pursell B, Chang C, Shaw LM, Mao J, Simin K, Kumar P, Vander Kooi CW, Shultz LD, Greiner DL, Norum JH, Toftgard R, Kuperwasser C, Mercurio AM. GLI1 regulates a novel neuropilin-2/a6?1 integrin based autocrine pathway that contributes to breast cancer initiation. EMBO Mol Med. 2013 Apr; 5(4):488-508.
Score: 0.006
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Hickey RD, Galivo F, Schug J, Brehm MA, Haft A, Wang Y, Benedetti E, Gu G, Magnuson MA, Shultz LD, Lagasse E, Greiner DL, Kaestner KH, Grompe M. Generation of islet-like cells from mouse gall bladder by direct ex vivo reprogramming. Stem Cell Res. 2013 Jul; 11(1):503-15.
Score: 0.006
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Seymour R, Shirley BJ, Hogenesch H, Shultz LD, Sundberg JP. Loss of function of the mouse Sharpin gene results in Peyer's patch regression. PLoS One. 2013; 8(2):e55224.
Score: 0.006
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Shultz LD, Lane PW, Coman DR, Taylor S, Hall E, Lyons B, Wood BG, Schlager G. Hairpatches, a single gene mutation characterized by progressive renal disease and alopecia in the mouse. A potential model for a newly described heritable human disorder. Lab Invest. 1991 Nov; 65(5):588-600.
Score: 0.005
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Bankert RB, Balu-Iyer SV, Odunsi K, Shultz LD, Kelleher RJ, Barnas JL, Simpson-Abelson M, Parsons R, Yokota SJ. Humanized mouse model of ovarian cancer recapitulates patient solid tumor progression, ascites formation, and metastasis. PLoS One. 2011; 6(9):e24420.
Score: 0.005
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Libby SJ, Brehm MA, Greiner DL, Shultz LD, McClelland M, Smith KD, Cookson BT, Karlinsey JE, Kinkel TL, Porwollik S, Canals R, Cummings LA, Fang FC. Humanized nonobese diabetic-scid IL2rgammanull mice are susceptible to lethal Salmonella Typhi infection. Proc Natl Acad Sci U S A. 2010 Aug 31; 107(35):15589-94.
Score: 0.005
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Bernstein JM, Brooks SP, Lehman HK, Pope L, Sands A, Shultz LD, Bankert RB. Human nasal polyp microenvironments maintained in a viable and functional state as xenografts in NOD-scid IL2rgamma(null) mice. Ann Otol Rhinol Laryngol. 2009 Dec; 118(12):866-75.
Score: 0.005
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King MA, Covassin L, Brehm MA, Racki W, Pearson T, Leif J, Laning J, Fodor W, Foreman O, Burzenski L, Chase TH, Gott B, Rossini AA, Bortell R, Shultz LD, Greiner DL. Human peripheral blood leucocyte non-obese diabetic-severe combined immunodeficiency interleukin-2 receptor gamma chain gene mouse model of xenogeneic graft-versus-host-like disease and the role of host major histocompatibility complex. Clin Exp Immunol. 2009 Jul; 157(1):104-18.
Score: 0.005
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Chopra P, Diiorio P, Pino SC, Wilson SB, Phillips NE, Mordes JP, Rossini AA, Greiner DL, Shultz LD, Bortell R. Failure of alpha-galactosylceramide to prevent diabetes in virus-inducible models of type 1 diabetes in the rat. In Vivo. 2009 Mar-Apr; 23(2):195-201.
Score: 0.004
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Van Zant G, Shultz L. Hematologic abnormalities of the immunodeficient mouse mutant, viable motheaten (mev). Exp Hematol. 1989 Feb; 17(2):81-7.
Score: 0.004
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Giassi LJ, Pearson T, Shultz LD, Laning J, Biber K, Kraus M, Woda BA, Schmidt MR, Woodland RT, Rossini AA, Greiner DL. Expanded CD34+ human umbilical cord blood cells generate multiple lymphohematopoietic lineages in NOD-scid IL2rgamma(null) mice. Exp Biol Med (Maywood). 2008 Aug; 233(8):997-1012.
Score: 0.004
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Gaines P, Tien CW, Olins AL, Olins DE, Shultz LD, Carney L, Berliner N. Mouse neutrophils lacking lamin B-receptor expression exhibit aberrant development and lack critical functional responses. Exp Hematol. 2008 Aug; 36(8):965-76.
Score: 0.004
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Seymour RE, Hasham MG, Cox GA, Shultz LD, Hogenesch H, Roopenian DC, Sundberg JP. Spontaneous mutations in the mouse Sharpin gene result in multiorgan inflammation, immune system dysregulation and dermatitis. Genes Immun. 2007 Jul; 8(5):416-21.
Score: 0.004
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Leiter EH, Prochazka M, Shultz LD. Effect of immunodeficiency on diabetogenesis in genetically diabetic (db/db) mice. J Immunol. 1987 May 15; 138(10):3224-9.
Score: 0.004
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Yoshino M, Yamazaki H, Shultz LD, Hayashi S. Constant rate of steady-state self-antigen trafficking from skin to regional lymph nodes. Int Immunol. 2006 Nov; 18(11):1541-8.
Score: 0.004
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Adachi Y, Oyaizu H, Taketani S, Minamino K, Yamaguchi K, Shultz LD, Iwasaki M, Tomita M, Suzuki Y, Nakano K, Koike Y, Yasumizu R, Sata M, Hirama N, Kubota I, Fukuhara S, Ikehara S. Treatment and transfer of emphysema by a new bone marrow transplantation method from normal mice to Tsk mice and vice versa. Stem Cells. 2006 Sep; 24(9):2071-7.
Score: 0.004
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Taube C, Miyahara N, Ott V, Swanson B, Takeda K, Loader J, Shultz LD, Tager AM, Luster AD, Dakhama A, Gelfand EW. The leukotriene B4 receptor (BLT1) is required for effector CD8+ T cell-mediated, mast cell-dependent airway hyperresponsiveness. J Immunol. 2006 Mar 01; 176(5):3157-64.
Score: 0.004
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Thornley TB, Brehm MA, Markees TG, Shultz LD, Mordes JP, Welsh RM, Rossini AA, Greiner DL. TLR agonists abrogate costimulation blockade-induced prolongation of skin allografts. J Immunol. 2006 Feb 01; 176(3):1561-70.
Score: 0.004
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Mikaelian I, Hovick M, Silva KA, Burzenski LM, Shultz LD, Ackert-Bicknell CL, Cox GA, Sundberg JP. Expression of terminal differentiation proteins defines stages of mouse mammary gland development. Vet Pathol. 2006 Jan; 43(1):36-49.
Score: 0.004
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Jaeschke A, Rinc?n M, Doran B, Reilly J, Neuberg D, Greiner DL, Shultz LD, Rossini AA, Flavell RA, Davis RJ. Disruption of the Jnk2 (Mapk9) gene reduces destructive insulitis and diabetes in a mouse model of type I diabetes. Proc Natl Acad Sci U S A. 2005 May 10; 102(19):6931-5.
Score: 0.003
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Gordon EJ, Wicker LS, Peterson LB, Serreze DV, Markees TG, Shultz LD, Rossini AA, Greiner DL, Mordes JP. Autoimmune diabetes and resistance to xenograft transplantation tolerance in NOD mice. Diabetes. 2005 Jan; 54(1):107-15.
Score: 0.003
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Ishikawa F, Yasukawa M, Yoshida S, Nakamura K, Nagatoshi Y, Kanemaru T, Shimoda K, Shimoda S, Miyamoto T, Okamura J, Shultz LD, Harada M. Human cord blood- and bone marrow-derived CD34+ cells regenerate gastrointestinal epithelial cells. FASEB J. 2004 Dec; 18(15):1958-60.
Score: 0.003
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Banuelos SJ, Markees TG, Phillips NE, Appel MC, Cuthbert A, Leif J, Mordes JP, Shultz LD, Rossini AA, Greiner DL. Regulation of skin and islet allograft survival in mice treated with costimulation blockade is mediated by different CD4+ cell subsets and different mechanisms. Transplantation. 2004 Sep 15; 78(5):660-7.
Score: 0.003
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Shultz LD, Coman DR, Bailey CL, Beamer WG, Sidman CL. "Viable motheaten," a new allele at the motheaten locus. I. Pathology. Am J Pathol. 1984 Aug; 116(2):179-92.
Score: 0.003
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Kuzin II, Ugine GD, Barth RK, Shultz LD, Nahm MH, Young FM, Bottaro A. A new murine model of humoral immuno-deficiency specifically affects class switching to T-independent antigens. Eur J Immunol. 2004 Jul; 34(7):1807-16.
Score: 0.003
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Turgeon NA, Banuelos SJ, Shultz LD, Lyons BL, Iwakoshi N, Greiner DL, Mordes JP, Rossini AA, Appel MC. Alloimmune injury and rejection of human skin grafts on human peripheral blood lymphocyte-reconstituted non-obese diabetic severe combined immunodeficient beta2-microglobulin-null mice. Exp Biol Med (Maywood). 2003 Oct; 228(9):1096-104.
Score: 0.003
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Shultz LD, Bailey CL, Coman DR. Hematopoietic stem cell function in motheaten mice. Exp Hematol. 1983 Aug; 11(7):667-80.
Score: 0.003
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Pearson T, Markees TG, Serreze DV, Pierce MA, Marron MP, Wicker LS, Peterson LB, Shultz LD, Mordes JP, Rossini AA, Greiner DL. Genetic disassociation of autoimmunity and resistance to costimulation blockade-induced transplantation tolerance in nonobese diabetic mice. J Immunol. 2003 Jul 01; 171(1):185-95.
Score: 0.003
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Dell'Agnola C, Rabascio C, Mancuso P, Capillo M, Pruneri G, Gobbi A, Minucci S, Ronzoni S, Volorio S, Calabrese L, Tradati N, Martinelli G, Shultz L, Bertolini F. In vitro and in vivo hematopoietic potential of human stem cells residing in muscle tissue. Exp Hematol. 2002 Aug; 30(8):905-14.
Score: 0.003
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Hoffmann K, Dreger CK, Olins AL, Olins DE, Shultz LD, Lucke B, Karl H, Kaps R, M?ller D, Vay? A, Aznar J, Ware RE, Sotelo Cruz N, Lindner TH, Herrmann H, Reis A, Sperling K. Mutations in the gene encoding the lamin B receptor produce an altered nuclear morphology in granulocytes (Pelger-Hu?t anomaly). Nat Genet. 2002 Aug; 31(4):410-4.
Score: 0.003
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Grzanna R, Shultz LD. The contribution of mast cells to the histamine content of the central nervous system: a regional analysis. Life Sci. 1982 Jun 07; 30(23):1959-64.
Score: 0.003
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Shultz LD, Sweet HO, Davisson MT, Coman DR. 'Wasted', a new mutant of the mouse with abnormalities characteristic to ataxia telangiectasia. Nature. 1982 Jun 03; 297(5865):402-4.
Score: 0.003
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Lian ZX, Kita H, Okada T, Hsu T, Shultz LD, Dorshkind K, Ansari AA, Ikehara S, Naiki M, Gershwin ME. Increased frequency of pre-pro B cells in the bone marrow of New Zealand Black (NZB) mice: implications for a developmental block in B cell differentiation. Dev Immunol. 2002 Mar; 9(1):35-45.
Score: 0.003
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Khanna KV, Whaley KJ, Zeitlin L, Moench TR, Mehrazar K, Cone RA, Liao Z, Hildreth JE, Hoen TE, Shultz L, Markham RB. Vaginal transmission of cell-associated HIV-1 in the mouse is blocked by a topical, membrane-modifying agent. J Clin Invest. 2002 Jan; 109(2):205-11.
Score: 0.003
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Lian ZX, Okada T, Kita H, Hsu T, Shultz LD, Dorshkind K, Ansari AA, Naiki M, Ikehara S, Gershwin ME. Age-related alterations in the lymphohematopoietic and B-lineage precursor populations in NZB mice. Stem Cells. 2002; 20(4):293-300.
Score: 0.003
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Ballen KK, Valinski H, Greiner D, Shultz LD, Becker PS, Hsieh CC, Stewart FM, Quesenberry PJ. Variables to predict engraftment of umbilical cord blood into immunodeficient mice: usefulness of the non-obese diabetic--severe combined immunodeficient assay. Br J Haematol. 2001 Jul; 114(1):211-8.
Score: 0.003
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Taguchi N, Hashimoto Y, Hsu T, Ansari AA, Shultz L, Dorshkind K, Ikehara S, Naiki M, Gershwin ME. B cells are selectively associated with thymic cortical but not medullary pathology in NZB mice. J Autoimmun. 2001 Jun; 16(4):393-400.
Score: 0.003
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Taguchi N, Ansari A, Hsu T, Hashimoto Y, Dorshkind K, Shultz L, Naiki M, Gershwin ME. Increased expression of mXBP-1 (TREB-5) in thymic B cells in New Zealand mice. J Autoimmun. 2001 Jun; 16(4):401-10.
Score: 0.003
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Hamelmann E, Takeda K, Haczku A, Cieslewicz G, Shultz L, Hamid Q, Xing Z, Gauldie J, Gelfand EW. Interleukin (IL)-5 but not immunoglobulin E reconstitutes airway inflammation and airway hyperresponsiveness in IL-4-deficient mice. Am J Respir Cell Mol Biol. 2000 Sep; 23(3):327-34.
Score: 0.002
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Schwarze J, Cieslewicz G, Joetham A, Ikemura T, M?kel? MJ, Dakhama A, Shultz LD, Lamers MC, Gelfand EW. Critical roles for interleukin-4 and interleukin-5 during respiratory syncytial virus infection in the development of airway hyperresponsiveness after airway sensitization. Am J Respir Crit Care Med. 2000 Aug; 162(2 Pt 1):380-6.
Score: 0.002
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Sundberg JP, Boggess D, Bascom C, Limberg BJ, Shultz LD, Sundberg BA, King LE, Montagutelli X. Lanceolate hair-J (lahJ): a mouse model for human hair disorders. Exp Dermatol. 2000 Jun; 9(3):206-18.
Score: 0.002
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Taguchi N, Hashimoto Y, Naiki M, Farr AG, Boyd RL, Ansari AA, Shultz LD, Kotzin BL, Dorshkind K, Ikehara S, Gershwin ME. Abnormal thymic expression of epithelial cell adhesion molecule (EP-CAM) in New Zealand Black (NZB) mice. J Autoimmun. 1999 Dec; 13(4):393-404.
Score: 0.002
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Takeoka Y, Taguchi N, Shultz L, Boyd RL, Naiki M, Ansari AA, Gershwin ME. Apoptosis and the thymic microenvironment in murine lupus. J Autoimmun. 1999 Nov; 13(3):325-34.
Score: 0.002
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Markees TG, Serreze DV, Phillips NE, Sorli CH, Gordon EJ, Shultz LD, Noelle RJ, Woda BA, Greiner DL, Mordes JP, Rossini AA. NOD mice have a generalized defect in their response to transplantation tolerance induction. Diabetes. 1999 May; 48(5):967-74.
Score: 0.002
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Schwarze J, Cieslewicz G, Hamelmann E, Joetham A, Shultz LD, Lamers MC, Gelfand EW. IL-5 and eosinophils are essential for the development of airway hyperresponsiveness following acute respiratory syncytial virus infection. J Immunol. 1999 Mar 01; 162(5):2997-3004.
Score: 0.002
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Myint YY, Miyakawa K, Naito M, Shultz LD, Oike Y, Yamamura K, Takahashi K. Granulocyte/macrophage colony-stimulating factor and interleukin-3 correct osteopetrosis in mice with osteopetrosis mutation. Am J Pathol. 1999 Feb; 154(2):553-66.
Score: 0.002
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Miyamoto A, Kunisada T, Yamazaki H, Miyake K, Nishikawa SI, Sudo T, Shultz LD, Hayashi SI. Establishment and characterization of pro-B cell lines from motheaten mutant mouse defective in SHP-1 protein tyrosine phosphatase. Immunol Lett. 1998 Sep; 63(2):75-82.
Score: 0.002
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Vu TN, Lee TX, Ndoye A, Shultz LD, Pittelkow MR, Dahl MV, Lynch PJ, Grando SA. The pathophysiological significance of nondesmoglein targets of pemphigus autoimmunity. Development of antibodies against keratinocyte cholinergic receptors in patients with pemphigus vulgaris and pemphigus foliaceus. Arch Dermatol. 1998 Aug; 134(8):971-80.
Score: 0.002
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Markees TG, Phillips NE, Gordon EJ, Noelle RJ, Shultz LD, Mordes JP, Greiner DL, Rossini AA. Long-term survival of skin allografts induced by donor splenocytes and anti-CD154 antibody in thymectomized mice requires CD4(+) T cells, interferon-gamma, and CTLA4. J Clin Invest. 1998 Jun 01; 101(11):2446-55.
Score: 0.002
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Kapasi ZF, Qin D, Kerr WG, Kosco-Vilbois MH, Shultz LD, Tew JG, Szakal AK. Follicular dendritic cell (FDC) precursors in primary lymphoid tissues. J Immunol. 1998 Feb 01; 160(3):1078-84.
Score: 0.002
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Takeda K, Hamelmann E, Joetham A, Shultz LD, Larsen GL, Irvin CG, Gelfand EW. Development of eosinophilic airway inflammation and airway hyperresponsiveness in mast cell-deficient mice. J Exp Med. 1997 Aug 04; 186(3):449-54.
Score: 0.002
-
Hogan CJ, Shpall EJ, McNulty O, McNiece I, Dick JE, Shultz LD, Keller G. Engraftment and development of human CD34(+)-enriched cells from umbilical cord blood in NOD/LtSz-scid/scid mice. Blood. 1997 Jul 01; 90(1):85-96.
Score: 0.002
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Cashman JD, Lapidot T, Wang JC, Doedens M, Shultz LD, Lansdorp P, Dick JE, Eaves CJ. Kinetic evidence of the regeneration of multilineage hematopoiesis from primitive cells in normal human bone marrow transplanted into immunodeficient mice. Blood. 1997 Jun 15; 89(12):4307-16.
Score: 0.002
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Yoshida H, Hayashi S, Shultz LD, Yamamura K, Nishikawa S, Nishikawa S, Kunisada T. Neural and skin cell-specific expression pattern conferred by steel factor regulatory sequence in transgenic mice. Dev Dyn. 1996 Oct; 207(2):222-32.
Score: 0.002
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Heine D, Passmore HC, Patel V, Shultz LD, Ward-Bailey P, Cook SA, Davisson MT. Effect of the mouse scid mutation on meiotic recombination. Mamm Genome. 1996 Jul; 7(7):497-500.
Score: 0.002
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Zhong RK, Donnenberg AD, Shultz LD, Swerdlow SH, Lee E, Rubin J, Kozii R, Chen J, Griffin DL, Wilson J, Ball ED. Evaluation of monoclonal antibody-mediated anti-acute myeloid leukemia immunotherapy in a SCID/hu model. Leuk Res. 1996 Jul; 20(7):581-9.
Score: 0.002
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Araki M, Fukumatsu Y, Katabuchi H, Shultz LD, Takahashi K, Okamura H. Follicular development and ovulation in macrophage colony-stimulating factor-deficient mice homozygous for the osteopetrosis (op) mutation. Biol Reprod. 1996 Feb; 54(2):478-84.
Score: 0.002
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Lowry PA, Shultz LD, Greiner DL, Hesselton RM, Kittler EL, Tiarks CY, Rao SS, Reilly J, Leif JH, Ramshaw H, Stewart FM, Quesenberry PJ. Improved engraftment of human cord blood stem cells in NOD/LtSz-scid/scid mice after irradiation or multiple-day injections into unirradiated recipients. Biol Blood Marrow Transplant. 1996 Feb; 2(1):15-23.
Score: 0.002
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Blazar BR, Brennan CA, Broxmeyer HE, Shultz LD, Vallera DA. Transgenic mice expressing either bovine growth hormone (bGH) or human GH releasing hormone (hGRH) have increased splenic progenitor cell colony formation and DNA synthesis in vitro and in vivo. Exp Hematol. 1995 Dec; 23(13):1397-406.
Score: 0.002
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Serreze DV, Leiter EH, Hanson MS, Christianson SW, Shultz LD, Hesselton RM, Greiner DL. Emv30null NOD-scid mice. An improved host for adoptive transfer of autoimmune diabetes and growth of human lymphohematopoietic cells. Diabetes. 1995 Dec; 44(12):1392-8.
Score: 0.002
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Beamer WG, Pelsue SC, Shultz LD, Sundberg JP, Barker JE. The flaky skin (fsn) mutation in mice: map location and description of the anemia. Blood. 1995 Oct 15; 86(8):3220-6.
Score: 0.002
-
Green MC, Shultz LD. Motheaten, an immunodeficient mutant of the mouse. I. Genetics and pathology. J Hered. 1975 Sep-Oct; 66(5):250-8.
Score: 0.002
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Buhlmann JE, Foy TM, Aruffo A, Crassi KM, Ledbetter JA, Green WR, Xu JC, Shultz LD, Roopesian D, Flavell RA, et al. In the absence of a CD40 signal, B cells are tolerogenic. Immunity. 1995 Jun; 2(6):645-53.
Score: 0.002
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Rohane PW, Shimada A, Kim DT, Edwards CT, Charlton B, Shultz LD, Fathman CG. Islet-infiltrating lymphocytes from prediabetic NOD mice rapidly transfer diabetes to NOD-scid/scid mice. Diabetes. 1995 May; 44(5):550-4.
Score: 0.002
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Greiner DL, Shultz LD, Yates J, Appel MC, Perdrizet G, Hesselton RM, Schweitzer I, Beamer WG, Shultz KL, Pelsue SC, et al. Improved engraftment of human spleen cells in NOD/LtSz-scid/scid mice as compared with C.B-17-scid/scid mice. Am J Pathol. 1995 Apr; 146(4):888-902.
Score: 0.002
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Rajan TV, Bailis JM, Yates JA, Shultz LD, Greiner DL, Nelson FK. Maternal influence on susceptibility of offspring to Brugia malayi infection in a murine model of filariasis. Acta Trop. 1994 Dec; 58(3-4):283-9.
Score: 0.002
-
Smithson G, Beamer WG, Shultz KL, Christianson SW, Shultz LD, Kincade PW. Increased B lymphopoiesis in genetically sex steroid-deficient hypogonadal (hpg) mice. J Exp Med. 1994 Aug 01; 180(2):717-20.
Score: 0.002
-
Rajan TV, Nelson FK, Killeen N, Shultz LD, Yates JA, Bailis JM, Littman DR, Greiner DL. CD4+ T-lymphocytes are not required for murine resistance to the human filarial parasite, Brugia malayi. Exp Parasitol. 1994 Jun; 78(4):352-60.
Score: 0.002
-
Takahashi K, Umeda S, Shultz LD, Hayashi S, Nishikawa S. Effects of macrophage colony-stimulating factor (M-CSF) on the development, differentiation, and maturation of marginal metallophilic macrophages and marginal zone macrophages in the spleen of osteopetrosis (op) mutant mice lacking functional M-CSF activity. J Leukoc Biol. 1994 May; 55(5):581-8.
Score: 0.002
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Rajan TV, Nelson FK, Shultz LD, Shultz KL, Beamer WG, Yates J, Greiner DL. Influence of gonadal steroids on susceptibility to Brugia malayi in scid mice. Acta Trop. 1994 Apr; 56(4):307-14.
Score: 0.002
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Szomolanyi-Tsuda E, Dundon PL, Joris I, Shultz LD, Woda BA, Welsh RM. Acute, lethal, natural killer cell-resistant myeloproliferative disease induced by polyomavirus in severe combined immunodeficient mice. Am J Pathol. 1994 Feb; 144(2):359-71.
Score: 0.002
-
Kapasi ZF, Kosco-Vilbois MH, Shultz LD, Tew JG, Szakal AK. Cellular origin of follicular dendritic cells. Adv Exp Med Biol. 1994; 355:231-5.
Score: 0.002
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Yeoman H, Gress RE, Bare CV, Leary AG, Boyse EA, Bard J, Shultz LD, Harris DT, DeLuca D. Human bone marrow and umbilical cord blood cells generate CD4+ and CD8+ single-positive T cells in murine fetal thymus organ culture. Proc Natl Acad Sci U S A. 1993 Nov 15; 90(22):10778-82.
Score: 0.002
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Takahashi K, Naito M, Shultz LD, Hayashi S, Nishikawa S. Differentiation of dendritic cell populations in macrophage colony-stimulating factor-deficient mice homozygous for the osteopetrosis (op) mutation. J Leukoc Biol. 1993 Jan; 53(1):19-28.
Score: 0.001
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Prochazka M, Gaskins HR, Shultz LD, Leiter EH. The nonobese diabetic scid mouse: model for spontaneous thymomagenesis associated with immunodeficiency. Proc Natl Acad Sci U S A. 1992 Apr 15; 89(8):3290-4.
Score: 0.001
-
Martin A, Kimura H, Thung S, Fong P, Shultz LD, Davies TF. Characteristics of long-term human thyroid peroxidase autoantibody secretion in scid mice transplanted with lymphocytes from patients with autoimmune thyroiditis. Int Arch Allergy Immunol. 1992; 98(4):317-23.
Score: 0.001
-
Shultz LD, Wilder MS. Cytotoxicity of rabbit blood for Listeria monocytogenes. Infect Immun. 1971 Dec; 4(6):703-8.
Score: 0.001
-
Tennent BJ, Beamer WG, Shultz LD, Adamson ED. Epidermal growth factor receptors in spontaneous ovarian granulosa cell tumors of SWR-derived mice. Int J Cancer. 1989 Sep 15; 44(3):477-82.
Score: 0.001
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Beamer WG, Tennent BJ, Shultz KL, Nadeau JH, Shultz LD, Skow LC. Gene for ovarian granulosa cell tumor susceptibility, Gct, in SWXJ recombinant inbred strains of mice revealed by dehydroepiandrosterone. Cancer Res. 1988 Sep 15; 48(18):5092-5.
Score: 0.001